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  1. AU="Lucia Araujo-Chaveron"
  2. AU=Wong D H T AU=Wong D H T
  3. AU="Yassin, Heba A"
  4. AU="Blight, Colin R"
  5. AU="Tang, Jack"
  6. AU="Michael E. Dorcas"
  7. AU="Oliveira, Fernando Rocha de"
  8. AU="Rossmanith, R."
  9. AU="Xi He"
  10. AU="Somenath Mitra"
  11. AU=Zhao Limei AU=Zhao Limei
  12. AU="Feng, Sheau-Line"
  13. AU="Goldman, Nick"
  14. AU="Oumezzine, Ma"
  15. AU="Elena D. Nosyreva"
  16. AU="Birara, Sunita"
  17. AU=Banegas Matthew P. AU=Banegas Matthew P.
  18. AU="Mendelow, Alexander David"
  19. AU="Pereira, Taci"
  20. AU="Natalie Taylor"
  21. AU="Moradi, Tayebeh"
  22. AU="Ramesh C. Santra"
  23. AU="Selvarajah, Aravinda"
  24. AU="Vaisman, Adva"
  25. AU="Rádiková, Žofia"
  26. AU=Poulin Stphane P.

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  1. Artikel ; Online: Perception of the SARS-CoV-2 pandemic by pregnant women during the first lockdown in France

    Lucia Araujo-Chaveron / Alexandra Doncarli / Alexandre J. Vivanti / Benoît Salanave / Linda Lasbeur / Maud Gorza / Jocelyn Raude / Nolwenn Regnault

    Preventive Medicine Reports, Vol 27, Iss , Pp 101807- (2022)

    worry, perceived vulnerability, adoption and maintenance of prevention measures according to the Covimater study

    2022  

    Abstract: Background: We aimed to describe pregnant women’s worry about the SARS-CoV-2 pandemic, the associated reasons, their perceived vulnerability to this infection, and factors influencing continued poor/non-existent or decreased implementation of preventive ... ...

    Abstract Background: We aimed to describe pregnant women’s worry about the SARS-CoV-2 pandemic, the associated reasons, their perceived vulnerability to this infection, and factors influencing continued poor/non-existent or decreased implementation of preventive measures over time. Method: A cross-sectional study was conducted in July 2020 using a web-questionnaire completed by 500 women who were pregnant during the first lockdown in France (March–May 2020). Questions focused on worry caused by the pandemic, perceived vulnerability to infection by SARS-CoV-2 and implementation of preventive measures during and after lockdown. A robust variance Poisson regression model was used to estimate adjusted prevalence ratios (aPR) for perceived vulnerability and continued poor/non-existent or decreased implementation of preventive measures. Results: Participants felt significantly more vulnerable to infection than women of childbearing age who were included in a parallel study on the French general population, but were significantly less worried about the pandemic. Obese participants and those who unsuccessfully sought exchanges with healthcare professionals about their infection risk felt significantly more vulnerable (aPR = 1.32 95%CI[1.05–1.64] and 1.88 [1.43–2.48], respectively). Participants with continued poor/non-existent or decreased implementation of preventive measures two months after the lockdown ended were more likely to have experienced violence during the lockdown (2.06, [1.32–3.22]), or to live in areas less affected by the pandemic (1.66 [1.05–2.62]). A good knowledge of viral transmission (0.54 [0.30–0.97]) and a high perceived vulnerability score (0.66 [0.44–0.99]) were associated with maintained/increased implementation of preventive measures. Conclusions: Our results can guide prevention and support policies for pregnant women during pandemics, current or future.
    Schlagwörter SARS-CoV-2 ; Pregnant women ; Vulnerability ; Behaviour ; Lockdown ; Perception ; Medicine ; R
    Thema/Rubrik (Code) 150
    Sprache Englisch
    Erscheinungsdatum 2022-06-01T00:00:00Z
    Verlag Elsevier
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  2. Artikel ; Online: SARS-CoV-2 variants of concern in children and adolescents with COVID-19

    Nicola Low / Leonie Heron / Myrofora Goutaki / Yin Ting Lam / Arnaud G L'Huillier / Margarethe Wiedenmann / Aziz Mert Ipekci / Lucia Araujo-Chaveron / Nirmala Prajapati / Muhammad Irfanul Alam / Ivan Zhelyazkov

    BMJ Open, Vol 13, Iss

    a systematic review

    2023  Band 10

    Abstract: Objectives Infections by SARS-CoV-2 variants of concern (VOCs) might affect children and adolescents differently than earlier viral lineages. We aimed to address five questions about SARS-CoV-2 VOC infections in children and adolescents: (1) symptoms and ...

    Abstract Objectives Infections by SARS-CoV-2 variants of concern (VOCs) might affect children and adolescents differently than earlier viral lineages. We aimed to address five questions about SARS-CoV-2 VOC infections in children and adolescents: (1) symptoms and severity, (2) risk factors for severe disease, (3) the risk of infection, (4) the risk of transmission and (5) long-term consequences following a VOC infection.Design Systematic review.Data sources The COVID-19 Open Access Project database was searched up to 1 March 2022 and PubMed was searched up to 9 May 2022.Eligibility criteria We included observational studies about Alpha, Beta, Gamma, Delta and Omicron VOCs among ≤18-year-olds. We included studies in English, German, French, Greek, Italian, Spanish and Turkish.Data extraction and synthesis Two reviewers extracted and verified the data and assessed the risk of bias. We descriptively synthesised the data and assessed the risks of bias at the outcome level.Results We included 53 articles. Most children with any VOC infection presented with mild disease, with more severe disease being described with the Delta or the Gamma VOC. Diabetes and obesity were reported as risk factors for severe disease during the whole pandemic period. The risk of becoming infected with a SARS-CoV-2 VOC seemed to increase with age, while in daycare settings the risk of onward transmission of VOCs was higher for younger than older children or partially vaccinated adults. Long-term symptoms following an infection with a VOC were described in <5% of children and adolescents.Conclusion Overall patterns of SARS-CoV-2 VOC infections in children and adolescents are similar to those of earlier lineages. Comparisons between different pandemic periods, countries and age groups should be improved with complete reporting of relevant contextual factors, including VOCs, vaccination status of study participants and the risk of exposure of the population to SARS-CoV-2.PROSPERO registration number CRD42022295207.
    Schlagwörter Medicine ; R
    Thema/Rubrik (Code) 610
    Sprache Englisch
    Erscheinungsdatum 2023-10-01T00:00:00Z
    Verlag BMJ Publishing Group
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  3. Artikel ; Online: Mental health of pregnant women during the SARS-CoV-2 pandemic in France

    Alexandra Doncarli / Lucia Araujo-Chaveron / Catherine Crenn-Hebert / Marie-Noëlle Vacheron / Christophe Léon / Imane Khireddine / Francis Chin / Alexandra Benachi / Sarah Tebeka / Nolwenn Regnault

    PLoS ONE, Vol 18, Iss

    Evolution of self-perceived psychological state during the first lockdown, and anxiety frequency two months after the lockdown ended

    2023  Band 4

    Abstract: Previous pandemics and related lockdowns have had a deleterious impact on pregnant women’s mental health. We studied the impact of the SARS-CoV-2/Covid-19 pandemic and France’s first lockdown on pregnant women’s mental health. A cross-sectional study was ...

    Abstract Previous pandemics and related lockdowns have had a deleterious impact on pregnant women’s mental health. We studied the impact of the SARS-CoV-2/Covid-19 pandemic and France’s first lockdown on pregnant women’s mental health. A cross-sectional study was conducted in July 2020 using a web-questionnaire completed by 500 adult women who were pregnant during the first lockdown in France (March-May 2020). Questions focused on their self-perceived psychological state and affects they felt before and during the lockdown and anxiety symptomatology (HAD) two months after it ended. A robust variance Poisson regression model was used to estimate adjusted prevalence ratios (aPR) for anxiety and self-perceived psychological state evolution. One in five respondents (21.1%) reported psychological deterioration during lockdown. Associated determinants were: i) little or no social support (self-perceived) (aRP = 1.77, 95%CI[1.18–2.66]), ii) increased workload (1.65, [1.02–2.66]), and iii) poor/moderate knowledge about SARS-CoV-2 transmission (1.60, [1.09–2.35]). Seven percent of women reporting psychological deterioration had access to professional psychological support during lockdown, while 19% did not despite wanting it. Women reported heightened powerlessness (60.3%), frustration (64%) and fear (59.2%) during lockdown. One in seven respondents (14.2%, 95%CI[10.9–18.2]) had anxiety symptoms. Determinants associated: i) at least one pregnancy-related pathology (aPR = 1.82, 95%CI[1.15–2.88]), ii) overweightness or obesity (1.61, [1.07–2.43]), iii) one child under the age of six years in the household during the lockdown (3.26, [1.24–8.53]), iv) little or no social support (self-perceived) during the lockdown (1.66, [1.07–2.58]), v) friend or relatives diagnosed with Covid-19 or with symptoms of the disease (1.66; [1.06–2.60]), vi) no access to medication for psychological distress (2.86, [1.74–4.71]), and vii) unsuccessfully seeking exchanges with healthcare professionals about their pregnancy during the pandemic (1.66, ...
    Schlagwörter Medicine ; R ; Science ; Q
    Thema/Rubrik (Code) 150
    Sprache Englisch
    Erscheinungsdatum 2023-01-01T00:00:00Z
    Verlag Public Library of Science (PLoS)
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  4. Artikel ; Online: Pregnant women's unmet need to communicate with a health professional during the SARS-CoV-2 pandemic lockdown in France

    Lucia Araujo-Chaveron / Alexandra Doncarli / Catherine Crenn-Hebert / Virginie Demiguel / Julie Boudet-Berquier / Yaya Barry / Maria-Eugênia Gomes Do Espirito Santo / Andréa Guajardo-Villar / Claudie Menguy / Anouk Tabaï / Karine Wyndels / Alexandra Benachi / Nolwenn Regnault

    PLoS ONE, Vol 17, Iss 4, p e

    The Covimater cross-sectional study.

    2022  Band 0266996

    Abstract: During the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic lockdown, communication between pregnant women and health professionals may have become complicated due to restrictions on movement and saturated health services. This could ...

    Abstract During the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic lockdown, communication between pregnant women and health professionals may have become complicated due to restrictions on movement and saturated health services. This could have impacts on pregnancy monitoring and women's wellbeing. We aimed to i) describe the unmet need of pregnant women living in France to communicate with health professionals about the pandemic and their pregnancy during the lockdown, ii) assess the socio-demographic, medical and contextual factors associated with this unmet need. The Covimater cross-sectional study, conducted in July 2020, includes data on 500 adult women's experiences of pregnancy during the first lockdown period in France (i.e., from March to May 2020). The women, all residents in metropolitan France, answered a web-based questionnaire about their conversations with health professionals during the lockdown, as well as their social and medical characteristics. A robust variance Poisson regression model was used to estimate crude or adjusted prevalence ratios (aPRs) for their unmet need to communicate with health professionals about the pandemic and their pregnancy. Forty-one percent of participants reported an unmet need to communicate with a health professional during the lockdown, mainly about the risk of transmitting SARS-CoV-2 to their baby and the consequences for the latter. Factors associated were: i) being professionally inactive (aPR = 1.58,CI95%[(1.14-2.21]), ii) having an educational level below secondary school diploma (1.38,[1.05,-1.81]), iii) having experienced serious arguments/violence (2.12,[1.28-3.52]), iv) being very worried about the pandemic (1.41,[1.11-1.78]), v) being primiparous (1.36,[1.06-1.74]) and vi) having had pregnancy consultations postponed/cancelled by health professionals during the lockdown (1.35,[1.06-1.73]). These results can be used to develop targeted strategies that ensure pregnant women are able to i) communicate with health professionals about the ...
    Schlagwörter Medicine ; R ; Science ; Q
    Thema/Rubrik (Code) 360 ; 300
    Sprache Englisch
    Erscheinungsdatum 2022-01-01T00:00:00Z
    Verlag Public Library of Science (PLoS)
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  5. Artikel ; Online: Outbreaks of publications about emerging infectious diseases

    Aziz Mert Ipekci / Diana Buitrago-Garcia / Kaspar Walter Meili / Fabienne Krauer / Nirmala Prajapati / Shabnam Thapa / Lea Wildisen / Lucia Araujo-Chaveron / Lukas Baumann / Sanam Shah / Tessa Whiteley / Gonzalo Solís-García / Foteini Tsotra / Ivan Zhelyazkov / Hira Imeri / Nicola Low / Michel Jacques Counotte

    BMC Medical Research Methodology, Vol 21, Iss 1, Pp 1-

    the case of SARS-CoV-2 and Zika virus

    2021  Band 9

    Abstract: Abstract Background Outbreaks of infectious diseases generate outbreaks of scientific evidence. In 2016 epidemics of Zika virus emerged, and in 2020, a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a pandemic of coronavirus ... ...

    Abstract Abstract Background Outbreaks of infectious diseases generate outbreaks of scientific evidence. In 2016 epidemics of Zika virus emerged, and in 2020, a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a pandemic of coronavirus disease 2019 (COVID-19). We compared patterns of scientific publications for the two infections to analyse the evolution of the evidence. Methods We annotated publications on Zika virus and SARS-CoV-2 that we collected using living evidence databases according to study design. We used descriptive statistics to categorise and compare study designs over time. Results We found 2286 publications about Zika virus in 2016 and 21,990 about SARS-CoV-2 up to 24 May 2020, of which we analysed a random sample of 5294 (24%). For both infections, there were more epidemiological than laboratory science studies. Amongst epidemiological studies for both infections, case reports, case series and cross-sectional studies emerged first, cohort and case-control studies were published later. Trials were the last to emerge. The number of preprints was much higher for SARS-CoV-2 than for Zika virus. Conclusions Similarities in the overall pattern of publications might be generalizable, whereas differences are compatible with differences in the characteristics of a disease. Understanding how evidence accumulates during disease outbreaks helps us understand which types of public health questions we can answer and when.
    Schlagwörter Medicine (General) ; R5-920
    Sprache Englisch
    Erscheinungsdatum 2021-03-01T00:00:00Z
    Verlag BMC
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  6. Artikel ; Online: Occurrence and transmission potential of asymptomatic and presymptomatic SARS-CoV-2 infections

    Diana Buitrago-Garcia / Aziz Mert Ipekci / Leonie Heron / Hira Imeri / Lucia Araujo-Chaveron / Ingrid Arevalo-Rodriguez / Agustín Ciapponi / Muge Cevik / Anthony Hauser / Muhammad Irfanul Alam / Kaspar Meili / Eric A Meyerowitz / Nirmala Prajapati / Xueting Qiu / Aaron Richterman / William Gildardo Robles-Rodriguez / Shabnam Thapa / Ivan Zhelyazkov / Georgia Salanti /
    Nicola Low

    PLoS Medicine, Vol 19, Iss 5, p e

    Update of a living systematic review and meta-analysis.

    2022  Band 1003987

    Abstract: Background Debate about the level of asymptomatic Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection continues. The amount of evidence is increasing and study designs have changed over time. We updated a living systematic review to ... ...

    Abstract Background Debate about the level of asymptomatic Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection continues. The amount of evidence is increasing and study designs have changed over time. We updated a living systematic review to address 3 questions: (1) Among people who become infected with SARS-CoV-2, what proportion does not experience symptoms at all during their infection? (2) What is the infectiousness of asymptomatic and presymptomatic, compared with symptomatic, SARS-CoV-2 infection? (3) What proportion of SARS-CoV-2 transmission in a population is accounted for by people who are asymptomatic or presymptomatic? Methods and findings The protocol was first published on 1 April 2020 and last updated on 18 June 2021. We searched PubMed, Embase, bioRxiv, and medRxiv, aggregated in a database of SARS-CoV-2 literature, most recently on 6 July 2021. Studies of people with PCR-diagnosed SARS-CoV-2, which documented symptom status at the beginning and end of follow-up, or mathematical modelling studies were included. Studies restricted to people already diagnosed, of single individuals or families, or without sufficient follow-up were excluded. One reviewer extracted data and a second verified the extraction, with disagreement resolved by discussion or a third reviewer. Risk of bias in empirical studies was assessed with a bespoke checklist and modelling studies with a published checklist. All data syntheses were done using random effects models. Review question (1): We included 130 studies. Heterogeneity was high so we did not estimate a mean proportion of asymptomatic infections overall (interquartile range (IQR) 14% to 50%, prediction interval 2% to 90%), or in 84 studies based on screening of defined populations (IQR 20% to 65%, prediction interval 4% to 94%). In 46 studies based on contact or outbreak investigations, the summary proportion asymptomatic was 19% (95% confidence interval (CI) 15% to 25%, prediction interval 2% to 70%). (2) The secondary attack rate in contacts of people ...
    Schlagwörter Medicine ; R
    Thema/Rubrik (Code) 150 ; 306
    Sprache Englisch
    Erscheinungsdatum 2022-05-01T00:00:00Z
    Verlag Public Library of Science (PLoS)
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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