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Article ; Online: The genetic diversity of Plasmodium vivax

Wanessa Christina de Souza-Neiras / Luciane Moreno Storti de Melo / Ricardo Luiz Dantas Machado

Memórias do Instituto Oswaldo Cruz., Vol 102, Iss 3, Pp 245-

a review

2007  Volume 254

Abstract: The genetic diversity of Plasmodium vivax has been investigated in several malaria-endemic areas, including the Brazilian Amazon region, where this is currently the most prevalent species causing malaria in humans. This review summarizes current views on ...

Abstract The genetic diversity of Plasmodium vivax has been investigated in several malaria-endemic areas, including the Brazilian Amazon region, where this is currently the most prevalent species causing malaria in humans. This review summarizes current views on the use of molecular markers to examine P. vivax populations, with a focus on studies performed in Brazilian research laboratories. We emphasize the importance of phylogenetic studies on this parasite and discuss the perspectives created by our increasing understanding of genetic diversity and population structure of this parasite for the development of new control strategies, including vaccines, and more effective drugs for the treatment of P. vivax malaria.
Keywords malaria ; Plasmodium vivax ; genetic diversity ; molecular markers ; phylogeny ; evolution ; Arctic medicine. Tropical medicine ; RC955-962 ; Microbiology ; QR1-502
Language English
Publishing date 2007-06-01T00:00:00Z
Publisher Instituto Oswaldo Cruz, Ministério da Saúde
Document type Article ; Online
Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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