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  1. Article ; Online: The COVID-19 Pandemic and Ophthalmic Care

    Seán R. O’Connor / Charlene Treanor / Elizabeth Ward / Robin A. Wickens / Abby O’Connell / Lucy A. Culliford / Chris A. Rogers / Eleanor A. Gidman / Tunde Peto / Paul C. Knox / Benjamin J. L. Burton / Andrew J. Lotery / Sobha Sivaprasad / Barnaby C. Reeves / Ruth E. Hogg / Michael Donnelly / MONARCH Study Group

    International Journal of Environmental Research and Public Health, Vol 19, Iss 9488, p

    A Qualitative Study of Patients with Neovascular Age-Related Macular Degeneration (nAMD)

    2022  Volume 9488

    Abstract: Concerns have been expressed about the relationship between reduced levels of health care utilisation and the COVID-19 pandemic. This study aimed to elicit and explore the views of patients with neovascular age-related macular degeneration (nAMD) ... ...

    Abstract Concerns have been expressed about the relationship between reduced levels of health care utilisation and the COVID-19 pandemic. This study aimed to elicit and explore the views of patients with neovascular age-related macular degeneration (nAMD) regarding the COVID-19 pandemic and their ophthalmic care. Semi-structured telephone interviews were conducted with thirty-five patients with nAMD taking part in a larger diagnostic accuracy study of home-monitoring tests. Participants were recruited using maximum variation sampling to capture a range of key characteristics including age, gender and time since initial treatment. Transcribed interview data were analysed using a deductive and inductive thematic approach. Three themes emerged from the analysis: i. access to eye clinic care. ii. COVID-19-mitigating factors and care delivery and iii. social and personal circumstances. Participants reported anxieties about cancelled or delayed appointments, limited communication from clinic-based services about appointments, and the impact of this on their ongoing care. Despite these concerns, there was apprehension about attending appointments due to infection risk and a perception that nAMD patients are a ‘high risk’ group. Views of those who attended clinics during the study period were, however, positive, with social distancing and infection control measures providing reassurance. These findings contribute to our understanding about experiences of patients with nAMD during the COVID-19 pandemic and may have potential implications for future planning of care services in similar circumstances. Innovative approaches may be required to address issues related to access to care, including concerns about delayed or cancelled appointments.
    Keywords COVID-19 ; patient perspective ; ophthalmic care ; qualitative methods ; Medicine ; R
    Subject code 360
    Language English
    Publishing date 2022-08-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: A mixed-methods feasibility and external pilot study to inform a large pragmatic randomised controlled trial of the effects of surgical wound dressing strategies on surgical site infections (Bluebelle Phase B)

    The Bluebelle Study Group / Barnaby C. Reeves / Lazaros Andronis / Jane M. Blazeby / Natalie S. Blencowe / Melanie Calvert / Joanna Coast / Tim Draycott / Jenny L. Donovan / Rachael Gooberman-Hill / Robert J. Longman / Laura Magill / Jonathan M. Mathers / Thomas D. Pinkney / Chris A. Rogers / Leila Rooshenas / Andrew Torrance / Nicky J. Welton / Mark Woodward /
    Kate Ashton / Katarzyna D. Bera / Gemma L. Clayton / Lucy A. Culliford / Jo C. Dumville / Daisy Elliott / Lucy Ellis / Hannah Gould-Brown / Rhiannon C. Macefield / Christel McMullan / Caroline Pope / Dimitrios Siassakos / Sean Strong / Helen Talbot

    Trials, Vol 18, Iss 1, Pp 1-

    study protocol for a randomised controlled trial

    2017  Volume 12

    Abstract: Abstract Background Surgical site infections (SSIs) are common, occurring in up to 25% of > 4 million operations performed in England each year. Previous trials of the effect of wound dressings on the risk of developing a SSI are of poor quality and ... ...

    Abstract Abstract Background Surgical site infections (SSIs) are common, occurring in up to 25% of > 4 million operations performed in England each year. Previous trials of the effect of wound dressings on the risk of developing a SSI are of poor quality and underpowered. Methods/Design This study is a feasibility and pilot trial to examine the feasibility of a full trial that will compare simple dressings, no dressing and tissue-glue as a dressing. It is examining the overall acceptability of trial participation, identifying opportunities for refinement, testing the feasibility of and validating new outcome tools to assess SSI, wound management issues and patients’ wound symptom experiences. It is also exploring methods for avoiding performance bias and blinding outcome assessors by testing the feasibility of collecting wound photographs taken in theatre immediately after wound closure and, at 4–8 weeks after surgery, taken by participants themselves or their carers. Finally, it is identifying the main cost drivers for an economic evaluation of dressing types. Integrated qualitative research is exploring acceptability and reasons for non-adherence to allocation. Adults undergoing primary elective or unplanned abdominal general surgery or Caesarean section are eligible. The main exclusion criteria are abdominal or other major surgery less than three months before the index operation or contraindication to dressing allocation. The trial is scheduled to recruit for nine months. The findings will be used to inform the design of a main trial. Discussion This pilot trial is the first pragmatic study to randomise participants to no dressing or tissue-glue as a dressing versus a simple dressing. Early evidence from the ongoing pilot shows that recruitment is proceeding well and that the interventions are acceptable to participants. Combined with the qualitative findings, the findings will inform whether a main, large trial is feasible and, if so, how it should be designed. Trial registration ISRCTN49328913 . Registered on 20 ...
    Keywords Pilot study ; Feasibility study ; Randomised controlled trial ; Wound dressing ; Abdominal surgery ; Caesarean section ; Medicine (General) ; R5-920
    Language English
    Publishing date 2017-08-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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