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  1. Article: Left bundle branch pacing: a promising modality for cardiac resynchronisation therapy.

    Luermans, Justin G L M / Vernooy, Kevin

    Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation

    2023  Volume 31, Issue 4, Page(s) 138–139

    Language English
    Publishing date 2023-03-16
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 2211468-3
    ISSN 1876-6250 ; 1568-5888 ; 0929-7456
    ISSN (online) 1876-6250
    ISSN 1568-5888 ; 0929-7456
    DOI 10.1007/s12471-023-01773-4
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6216: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: Left-sided atrial tachycardia ablation in an atrial-esophageal fistula survivor.

    Chaldoupi, Sevasti-Maria / Maesen, Bart / Linz, Dominik / Luermans, Justin G L M

    HeartRhythm case reports

    2022  Volume 8, Issue 6, Page(s) 428–432

    Language English
    Publishing date 2022-03-18
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2834871-0
    ISSN 2214-0271
    ISSN 2214-0271
    DOI 10.1016/j.hrcr.2022.03.008
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  3. Article ; Online: Impedance drop during focal monopolar pulsed field ablation in the atrium.

    Farnir, Florent I P / Luermans, Justin G L M / Farnir, Frédéric P F J D J / Chaldoupi, Sevasti-Maria / Linz, Dominik

    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing

    2024  

    Language English
    Publishing date 2024-03-18
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1329179-8
    ISSN 1572-8595 ; 1383-875X
    ISSN (online) 1572-8595
    ISSN 1383-875X
    DOI 10.1007/s10840-024-01793-z
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5214: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Innovations and paradigm shifts in atrial fibrillation ablation.

    Mulder, Bart A / Luermans, Justin G L M / Hindricks, Gerhard / Blaauw, Yuri

    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

    2021  Volume 23, Issue 23 Suppl 2, Page(s) ii23–ii27

    Abstract: Treatment of symptomatic atrial fibrillation has seen important changes in the past decades. Advancements have especially been made in the field of non-pharmacological treatment of this disease. Patients in whom a rhythm control strategy is chosen the ... ...

    Abstract Treatment of symptomatic atrial fibrillation has seen important changes in the past decades. Advancements have especially been made in the field of non-pharmacological treatment of this disease. Patients in whom a rhythm control strategy is chosen the place of catheter ablation has become more frontline therapy in the past years. The procedure itself has also seen changes in technologies that can be used, either using point-by-point radiofrequency or one of the single-shot techniques. One of the major limitations that remain is that re-do procedures are often necessary due to incomplete pulmonary vein isolation and/or atrial fibrillation being initiated by other mechanisms than pulmonary vein triggers. Therefore, there is further need for developing ablation tools that reproducibly isolate the pulmonary vein transmurally. Furthermore, addressing the underlying conditions before and after catheter ablation has been shown to be of great importance. In this review, we will give an overview of the evolution of catheter ablation, highlight the latest technologies and their future endeavours, and lifestyle modifications are being discussed as part of the catheter ablation strategy.
    MeSH term(s) Atrial Fibrillation/diagnosis ; Atrial Fibrillation/surgery ; Catheter Ablation/adverse effects ; Humans ; Pulmonary Veins/surgery ; Treatment Outcome
    Language English
    Publishing date 2021-03-22
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1449879-0
    ISSN 1532-2092 ; 1099-5129
    ISSN (online) 1532-2092
    ISSN 1099-5129
    DOI 10.1093/europace/euaa418
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5434: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Left atrial function of patients with atrial fibrillation undergoing thoracoscopic hybrid ablation.

    van der Heijden, Claudia A J / Adriaans, Bouke P / van Kuijk, Sander M J / Luermans, Justin G L M / Chaldoupi, Sevasti-Marisevi / Maessen, Jos G / Bidar, Elham / Maesen, Bart

    Interdisciplinary cardiovascular and thoracic surgery

    2024  Volume 38, Issue 4

    Abstract: Objectives: Thoracoscopic hybrid ablation is an effective and safe rhythm control strategy for patients with complex forms of atrial fibrillation. Its effect on left atrial function has not yet been studied.: Methods: In a retrospective single-centre ...

    Abstract Objectives: Thoracoscopic hybrid ablation is an effective and safe rhythm control strategy for patients with complex forms of atrial fibrillation. Its effect on left atrial function has not yet been studied.
    Methods: In a retrospective single-centre analysis of patients undergoing thoracoscopic hybrid ablation, the left atrial emptying fraction was calculated using the biplane modified Simpson method in the apical 2- and 4-chamber views on transthoracic echocardiography. Left atrial strain (reservoir, conduction and contractility) was quantified using dedicated software.
    Results: Sixty-seven patients were included (mean age 64 years, long-standing persistent atrial fibrillation in 69%, median atrial fibrillation history duration 64 months). At baseline, left atrial function and contractility were poor. The reservoir and contractile strain improved postprocedure compared to baseline [15 (standard deviation (SD): 8) and 17 (SD: 6); P = 0.013; 3 (SD: 5) and 4 (SD: 4), P = 0.008], whereas the left atrial volume indexed to the body surface area was reduced [51 ml/m2 (SD: 14) and 47 ml/m2 (SD: 18), P = 0.0024]. In patients with preoperative (long-standing) persistent atrial fibrillation and in patients with rhythm restoration, improvements in the emptying fraction, (reservoir and contractile) strain and the left ventricular ejection fraction were observed, whereas the left atrial volume decreased (P < 0.05).
    Conclusions: In this cohort of patients with severely diseased left atria, improvement in left atrial contractility and in the emptying fraction after thoracoscopic hybrid ablation for atrial fibrillation in patients with persistent atrial fibrillation is mainly due to rhythm restoration. Interestingly, the procedure itself also results in improved left atrial reservoir strain and reversed left atrial remodelling by reducing left atrial volume.
    Language English
    Publishing date 2024-04-02
    Publishing country England
    Document type Journal Article
    ISSN 2753-670X
    ISSN (online) 2753-670X
    DOI 10.1093/icvts/ivae061
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  6. Article: Successful thoracoscopic clipping of a thrombus-containing left atrial appendage.

    Vroomen, Mindy / Luermans, Justin G L M / Meir, Mark La / Maesen, Bart

    International journal of cardiology. Heart & vasculature

    2020  Volume 26, Page(s) 100460

    Language English
    Publishing date 2020-01-05
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 2818464-6
    ISSN 2352-9067
    ISSN 2352-9067
    DOI 10.1016/j.ijcha.2019.100460
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  7. Article: Multi-modal characterization of the left atrium by a fully automated integration of pre-procedural cardiac imaging and electro-anatomical mapping.

    Hermans, Ben J M / Bijvoet, Geertruida P / Holtackers, Robert J / Mihl, Casper / Luermans, Justin G L M / Maesen, Bart / Vernooy, Kevin / Linz, Dominik / Chaldoupi, Sevasti-Maria / Schotten, Ulrich

    International journal of cardiology. Heart & vasculature

    2023  Volume 49, Page(s) 101276

    Abstract: Background: The combination of information obtained from pre-procedural cardiac imaging and electro-anatomical mapping (EAM) can potentially help to locate new ablation targets. In this study we developed and evaluated a fully automated technique to ... ...

    Abstract Background: The combination of information obtained from pre-procedural cardiac imaging and electro-anatomical mapping (EAM) can potentially help to locate new ablation targets. In this study we developed and evaluated a fully automated technique to align left atrial (LA) anatomies obtained from CT- and MRI-scans with LA anatomies obtained from EAM.
    Methods: Twenty-one patients scheduled for a pulmonary vein (PV) isolation with a pre-procedural MRI were enrolled. Additionally, a recent computed tomography (CT) scan was available in 12 patients. LA anatomies were segmented from MRI-scans using ADAS-AF (Galgo Medical, Barcelona) and from the CT-scans using Slicer3D. MRI and CT anatomies were aligned with the EAM anatomy using an iterative closest plane-to-plane algorithm. Initially, the algorithm included the PVs, LA appendage and mitral valve anulus as they are the most distinctive landmarks. Subsequently, the algorithm was applied again, excluding these structures, with only three iterative steps to refine the alignment of the true LA surface. The result of the alignments was quantified by the Euclidian distance between the aligned anatomies after excluding PVs, LA appendage and mitral anulus.
    Results: Our algorithm successfully aligned 20/21 MRI anatomies and 11/12 CT anatomies with the corresponding EAM anatomies. The average median residual distances were 1.9 ± 0.6 mm and 2.5 ± 0.8 mm for MRI and CT anatomies respectively. The average LA surface with a residual distance less than 5.00 mm was 89 ± 9% and 89 ± 10% for MRI and CT anatomies respectively.
    Conclusion: An iterative closest plane-to-plane algorithm is a reliable method to automatically align pre-procedural cardiac images with anatomies acquired during ablation procedures.
    Language English
    Publishing date 2023-10-11
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 2818464-6
    ISSN 2352-9067
    ISSN 2352-9067
    DOI 10.1016/j.ijcha.2023.101276
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  8. Article: Left Bundle Branch Area Pacing and Atrioventricular Node Ablation in a Single-Procedure Approach for Elderly Patients with Symptomatic Atrial Fibrillation.

    Rijks, Jesse H J / Lankveld, Theo / Manusama, Randolph / Broers, Bernard / Stipdonk, Antonius M W van / Chaldoupi, Sevasti Maria / Bekke, Rachel M A Ter / Schotten, Ulrich / Linz, Dominik / Luermans, Justin G L M / Vernooy, Kevin

    Journal of clinical medicine

    2023  Volume 12, Issue 12

    Abstract: Background: Implantation of a permanent pacemaker and atrioventricular (AV) node ablation (pace-and-ablate) is an established approach for rate and symptom control in elderly patients with symptomatic atrial fibrillation (AF). Left bundle branch area ... ...

    Abstract Background: Implantation of a permanent pacemaker and atrioventricular (AV) node ablation (pace-and-ablate) is an established approach for rate and symptom control in elderly patients with symptomatic atrial fibrillation (AF). Left bundle branch area pacing (LBBAP) is a physiological pacing strategy that might overcome right ventricular pacing-induced dyssynchrony. In this study, the feasibility and safety of performing LBBAP and AV node ablation in a single procedure in the elderly was investigated.
    Methods: Consecutive patients with symptomatic AF referred for pace-and-ablate underwent the treatment in a single procedure. Data on procedure-related complications and lead stability were collected at regular follow-up at one day, ten days and six weeks after the procedure and continued every six months thereafter.
    Results: 25 patients (mean age 79.2 ± 4.2 years) were included and underwent successful LBBAP. In 22 (88%) patients, AV node ablation and LBBAP were performed in the same procedure. AV node ablation was postponed in two patients due to lead-stability concerns and in one patient on their own request. No complications related to the single-procedure approach were observed with no lead-stability issues at follow-up.
    Conclusions: LBBAP combined with AV node ablation in a single procedure is feasible and safe in elderly patients with symptomatic AF.
    Language English
    Publishing date 2023-06-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12124028
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  9. Article: Hybrid atrial fibrillation ablation.

    van der Heijden, Claudia A J / Aerts, Luca / Chaldoupi, Sevasti-Marisevi / van Cruchten, Cas / Kawczynski, Michal / Heuts, Samuel / Bidar, Elham / Luermans, Justin G L M / Maesen, Bart

    Annals of cardiothoracic surgery

    2023  Volume 13, Issue 1, Page(s) 54–70

    Abstract: In this state-of-the art review on hybrid atrial fibrillation (AF) ablation, we briefly focus on the pathophysiology of AF, the rationale for the hybrid approach, its technical aspects and the efficacy and safety outcomes after hybrid AF ablation, both ... ...

    Abstract In this state-of-the art review on hybrid atrial fibrillation (AF) ablation, we briefly focus on the pathophysiology of AF, the rationale for the hybrid approach, its technical aspects and the efficacy and safety outcomes after hybrid AF ablation, both from meta-analyses and randomized control trial data. Also, we performed a systematic search to provide a provisional overview of real-world hybrid AF ablation efficacy and safety outcomes. Furthermore, we give an insight into the 'Maastricht approach', an approach that allows us to tailor the ablation procedure to the individual patient. Finally, we reflect on future perspectives with the objective to continue improving our thoracoscopic hybrid AF ablation approach. Based on the review of the available literature, we believe it is fair to state that thoracoscopic hybrid AF ablation is a valid alternative to catheter ablation for the treatment of patients with more persistent forms of AF.
    Language English
    Publishing date 2023-12-13
    Publishing country China
    Document type Journal Article ; Review
    ZDB-ID 2713627-9
    ISSN 2304-1021 ; 2225-319X
    ISSN (online) 2304-1021
    ISSN 2225-319X
    DOI 10.21037/acs-2023-afm-0129
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  10. Article ; Online: Epicardial box lesion using bipolar biparietal radiofrequency and multimodality scar evaluation-a case series.

    Bijvoet, Geertruida Petronella / Chaldoupi, Sevasti-Maria / Bidar, Elham / Holtackers, Robert J / Luermans, Justin G L M / Maesen, Bart

    European heart journal. Case reports

    2021  Volume 6, Issue 1, Page(s) ytab530

    Abstract: Background: Surgical epicardial atrial fibrillation (AF) ablation can be performed as a stand-alone (thoracoscopic) procedure or concomitant to other cardiac surgery. In hybrid AF ablation thoracoscopic surgical epicardial ablation is combined with a ... ...

    Abstract Background: Surgical epicardial atrial fibrillation (AF) ablation can be performed as a stand-alone (thoracoscopic) procedure or concomitant to other cardiac surgery. In hybrid AF ablation thoracoscopic surgical epicardial ablation is combined with a percutaneous endocardial ablation. The Medtronic Gemini-S clamp is a surgical tool that uses irrigated bipolar biparietal radiofrequency (RF) energy applied with two clamp lesions that overlap to create one epicardial box lesion including the posterior left atrial wall and the pulmonary veins.
    Case summary: We describe three patients with therapy-refractory persistent AF and different stages of atrial remodelling in whom the Medtronic Cardioblate Gemini-S Irrigated RF Surgical Ablation System was used for hybrid AF ablation. Acute endocardial validation at the end of the hybrid ablation revealed a complete box lesion in all three cases. At 2-year follow-up, two out of three patients had recurrence of atrial arrhythmias. Invasive electro-anatomical mapping confirmed the persistence of the box lesion, and the mechanism of arrhythmia recurrence in both patients was unrelated to posterior left atrium or the pulmonary veins. The third patient has been without arrhythmia symptoms since the ablation procedure. A three-dimensional late gadolinium enhancement magnetic resonance imaging illustrates the ablation scar non-invasively in two cases.
    Discussion: Thoracoscopic biparietal RF AF ablation with the Medtronic Cardioblate Gemini-S Irrigated RF Surgical Ablation System results in permanent transmural scar formation, irrespective of the stage of atrial remodelling, as shown in this small population by means of multimodality scar evaluation.
    Language English
    Publishing date 2021-12-27
    Publishing country England
    Document type Case Reports
    ISSN 2514-2119
    ISSN (online) 2514-2119
    DOI 10.1093/ehjcr/ytab530
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