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  1. Article ; Conference proceedings: UNDERWATER ENDOSCOPIC SUBMUCOSAL DISSECTION OF A RECURRENT COLONIC ADENOMA

    Luglio, G. / Cecinato, P.

    Endoscopy

    2022  Volume 54, Issue S 01

    Event/congress ESGE Days 2022, Prague, Czech Republic, 2022-04-28
    Language English
    Publishing date 2022-04-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/s-0042-1744826
    Database Thieme publisher's database

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  2. Article ; Online: Surgical Techniques and Risk of Postoperative Recurrence in CD: A Game Changer?

    Luglio, Gaetano / Kono, Toru

    Inflammatory intestinal diseases

    2021  Volume 7, Issue 1, Page(s) 21–27

    Abstract: Background: Since its first description, the role of surgery in Crohn's disease (CD) has always been controversial; in fact, it has been mainly considered as a gastroenterological disease for long time. Nevertheless, despite great advances in medical ... ...

    Abstract Background: Since its first description, the role of surgery in Crohn's disease (CD) has always been controversial; in fact, it has been mainly considered as a gastroenterological disease for long time. Nevertheless, despite great advances in medical therapy, up to 70-80% of patients with CD will require surgery in their lifetime and up to 30% of them will undergo repeated surgeries due to recurrences. For these reasons, the idea of surgery as a tool in the therapeutic armamentarium to consider even in the early stage of the disease has progressively spread in the last decades, even corroborated by reports showing how primary surgery is able to definitively treat around half of the patients at long-term follow-up. More surgeons are nowadays more and more involved in developing techniques to reduce recurrences that have always been considered as part of the natural history of the disease so far.
    Summary: In this review, we will go through the role of surgery in the management of CD, showing the potential benefits of an early surgical approach as well as the impact of surgical research in the natural history of the disease. From this standpoint, we will show the role of different anastomotic configurations, emphasizing how more and more data are definitively establishing the impact of the novel Kono-S anastomosis in reducing endoscopic and surgical recurrence. Mesentery-based surgery is a novel and appealing surgical perspective, but more data are required.
    Key messages: Surgery has demonstrated to be a crucial tool in the therapeutic armamentarium for the management of CD. Early surgery and novel surgical techniques, such as the Kono-S anastomosis, may have an impact on the natural history of the disease, including the possibility to prevent recurrences.
    Language English
    Publishing date 2021-05-21
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2817967-5
    ISSN 2296-9365 ; 2296-9403
    ISSN (online) 2296-9365
    ISSN 2296-9403
    DOI 10.1159/000515372
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Potential Diagnostic Role of Hepcidin in Anemic Patients Affected by Inflammatory Bowel Disease: A Systematic Review.

    Ferrari, Fabiana / Carini, Mattia / Zanella, Isabella / Treglia, Giorgio / Luglio, Gaetano / Bresciani, Roberto / Biasiotto, Giorgio

    Diagnostics (Basel, Switzerland)

    2024  Volume 14, Issue 4

    Abstract: Background: Anemia is the main extraintestinal comorbidity of Inflammatory Bowel Disease (IBD). Differentiating the type of anemia in these disorders is still a challenge. Hepcidin could be a promising biomarker to identify iron deficiency anemia (IDA), ...

    Abstract Background: Anemia is the main extraintestinal comorbidity of Inflammatory Bowel Disease (IBD). Differentiating the type of anemia in these disorders is still a challenge. Hepcidin could be a promising biomarker to identify iron deficiency anemia (IDA), anemia of chronic disease (ACD) and the concomitant presence of both IDA and ACD.
    Methods: To evaluate the potential role of hepcidin dosage in the management of anemia in IBD patients, we performed a systematic review by a comprehensive literature analysis of original papers reporting the dosage of hepcidin in IBD patients. In all the articles reviewed, the dosage of ferritin was reported, and the correlation between hepcidin and ferritin has been used to compare these two biomarkers.
    Results: A total of 12 articles concerning the dosage of hepcidin in IBD were included, comprising in total of 976 patients. The results of the hepcidin values in IBD patients when compared with controls were conflicting. In fact, four articles described an increase in this biomarker, three showed a decrease and five did not find significant differences. The correlation with ferritin was positive and significant. In three studies, some differences between hepcidin dosages and ferritin levels indicate a possible role when IDA and ACD could be present at the same time.
    Conclusions: Considering the contradictory data of the studies, the diagnostic role of hepcidin as a biomarker remains elusive in IBD patients. These differences could be due to the clinical characteristics of the patients enrolled that should be better defined in the future. A suitable clinical trial should be designed to outline the possible role of hepcidin in differentiating IDA, ACD and concomitant IDA and ACD in IBD patients. At the moment, ferritin still remains the best marker to diagnose these conditions, in addition to hemoglobin, transferrin saturation and CRP as recommended by the ECCO guidelines.
    Language English
    Publishing date 2024-02-09
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics14040375
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  4. Article ; Conference proceedings: Does Underwater endoscopic submucosal dissection increase dissection speed in right colonic adenomas? A single center experience

    Cecinato, P. / Luglio, G. / Ciranni, F. / Coppini, F. / Lucarini, M. / Bassi, F. / Sassatelli, R.

    Endoscopy

    2023  Volume 55, Issue S 02

    Event/congress ESGE Days 2023, Dublin, Ireland, 2023-04-20
    Language English
    Publishing date 2023-04-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/s-0043-1766002
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  5. Article ; Conference proceedings: Underwater peroral esophageal myotomy to prevent insufflation related complications

    Luglio, G. / Cecinato, P. / Ciranni, F. / Bassi, F. / Di Marco, M. / Sassatelli, R.

    Endoscopy

    2023  Volume 55, Issue S 02

    Event/congress ESGE Days 2023, Dublin, Ireland, 2023-04-20
    Language English
    Publishing date 2023-04-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/s-0043-1765337
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  6. Article ; Online: Ultrasonographic diagnosis of ileo-ileal intussusception secondary to Vanek's tumor.

    Rispo, A / De Sire, R / D'Armiento, M / De Bonis, L / Tropeano, F P / Ricciolino, S / Nardone, G / Luglio, G

    European review for medical and pharmacological sciences

    2022  Volume 26, Issue 2, Page(s) 350–353

    Abstract: Intussusception is a common condition of bowel obstruction in pediatric patients. However, 5% of all cases occur in adults, mostly aged over fifty, with no difference based on sex, representing about 1% of all causes of bowel obstruction. Compared to ... ...

    Abstract Intussusception is a common condition of bowel obstruction in pediatric patients. However, 5% of all cases occur in adults, mostly aged over fifty, with no difference based on sex, representing about 1% of all causes of bowel obstruction. Compared to pediatric population, it is triggered by a pathologic lead point in about 85% of cases, represented in 60% of cases by malignant and benign neoplasms. Among these neoplasms, an inflammatory fibroid polyp (IFP), a benign neoplastic submucosal lesion also known as Vanek's tumor, is considered a very uncommon cause of adult intussusception. Clinical presentation could differ by location and size of tumor, and may include abdominal pain, nausea, vomiting, diarrhea or constipation, bleeding, weight loss, palpable abdominal mass, bowel obstruction, and gastrointestinal bleeding. Considering its common and non-specific symptoms, radiologic imaging plays a key role in the diagnosis of an IFP, especially computed tomography (CT) scan, which represents the most sensitive modality to confirm intussusception. However, bowel sonography (BS) has become an accurate procedure in various pathological intestinal diseases, also including intussusception. In this paper, we report a rare case of ileo-ileal intussusception secondary to Vanek's tumor diagnosed by BS.
    MeSH term(s) Adult ; Aged ; Child ; Humans ; Ileal Diseases/diagnosis ; Ileal Diseases/etiology ; Ileal Diseases/pathology ; Ileum/pathology ; Intestinal Obstruction/complications ; Intestinal Polyps/pathology ; Intussusception/diagnostic imaging ; Intussusception/etiology ; Neoplasms/pathology
    Language English
    Publishing date 2022-02-03
    Publishing country Italy
    Document type Case Reports ; Journal Article
    ZDB-ID 605550-3
    ISSN 2284-0729 ; 1128-3602 ; 0392-291X
    ISSN (online) 2284-0729
    ISSN 1128-3602 ; 0392-291X
    DOI 10.26355/eurrev_202201_27859
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Editorial: Abdominal and Perianal Fistulizing Crohn's Disease: Imaging, Surgical Techniques and Basic Research.

    Luglio, Gaetano / Tropeano, Francesca Paola / Pagano, Gianluca / Cricrì, Michele

    Frontiers in surgery

    2022  Volume 9, Page(s) 952874

    Language English
    Publishing date 2022-06-28
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2773823-1
    ISSN 2296-875X
    ISSN 2296-875X
    DOI 10.3389/fsurg.2022.952874
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  8. Article ; Online: Stapled versus handsewn methods for ileocolic anastomoses.

    Luglio, Gaetano / Corcione, Francesco

    Techniques in coloproctology

    2019  Volume 23, Issue 11, Page(s) 1093–1095

    Abstract: Background: This is the first systematic review specifically investigating ileocolic anastomosis.: Objectives: To compare outcomes of ileocolic anastomoses performed using stapling and handsewn techniques. The hypothesis tested was that the stapling ... ...

    Abstract Background: This is the first systematic review specifically investigating ileocolic anastomosis.
    Objectives: To compare outcomes of ileocolic anastomoses performed using stapling and handsewn techniques. The hypothesis tested was that the stapling technique is associated with fewer complications.
    Search strategy: MEDLINE, EMBASE, Cochrane Colorectal Cancer Group specialised register SR-COLOCA, and Cochrane Library were searched for randomised controlled trials comparing the use of a linear cutter stapler with any type of suturing technique for ileocolic anastomoses in adults from 1970 to 2005. Selection criteria were randomised controlled trials comparing the use of linear cutter stapler (isoperistaltic side to side or functional end to end) with any type of suturing technique in adults. Regarding data collection and analysis, eligible studies were selected and their methodological quality assessed. Sub-group analyses for cancer and inflammatory bowel disease as indication for ileocolic anastomoses were performed.
    Results: Six trials (including one unpublished) with 955 ileocolic participants were included. The three largest trials had adequate allocation concealment. Stapled anastomosis was associated with significantly fewer anastomotic leaks compared with the handsewn technique (S = 5/357, HS = 36/598, OR 0.34 [0.14, 0.82] p = 0.02). For the sub-group of 825 cancer patients in four studies, stapled anastomosis led to significantly fewer anastomotic leaks (S = 4/300, HS = 35/525, OR 0.28 [0.10, 0.75] p = 0.01). There were very less Crohn's disease patients to perform a sub-group analysis. All other outcomes showed no significant difference.
    Conclusions: Stapled functional end-to-end ileocolic anastomosis is associated with fewer leaks than handsewn anastomosis.
    MeSH term(s) Anastomosis, Surgical/adverse effects ; Anastomosis, Surgical/methods ; Anastomotic Leak/etiology ; Colon/surgery ; Humans ; Ileum/surgery ; Randomized Controlled Trials as Topic ; Surgical Stapling/adverse effects ; Surgical Stapling/methods
    Language English
    Publishing date 2019-11-15
    Publishing country Italy
    Document type Comparative Study ; Journal Article ; Systematic Review
    ZDB-ID 2083309-X
    ISSN 1128-045X ; 1123-6337
    ISSN (online) 1128-045X
    ISSN 1123-6337
    DOI 10.1007/s10151-019-02105-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Conference proceedings: Factors affecting dissection speed in endoscopic submucosal dissection (ESD) of colorectal superficial lesions

    Cecinato, P. / Lucarini, M. / Costetti, M. / Luglio, G. / Azzolini, F. / Lisotti, A. / Fusaroli, P. / Sassatelli, R.

    Endoscopy

    2023  Volume 55, Issue S 02

    Event/congress ESGE Days 2023, Dublin, Ireland, 2023-04-20
    Language English
    Publishing date 2023-04-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/s-0043-1765742
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  10. Article ; Online: Medical Education in Naples, Italy, at the Time of SARS-CoV-2

    Pagano, Gianluca / Luglio, Gaetano

    International Journal of Medical Students; Vol. 8 No.; 51-53 ; 2076-6327

    2020  Volume 1

    Abstract: SARS-CoV-2 pandemic dramatically changed our daytime routine. Our university world was deeply affected by this emergency situation and had to guarantee the teaching activity with online lessons and exams. While it is true that even in non-emergency ... ...

    Abstract SARS-CoV-2 pandemic dramatically changed our daytime routine. Our university world was deeply affected by this emergency situation and had to guarantee the teaching activity with online lessons and exams. While it is true that even in non-emergency conditions online teching is an integral part of many universities, the same cannot be said for graduation ceremonies. And what about students' clinical practice and research activity?In the present article, we will discuss about the experiences of a final-year medical student and of a young assistant professor of Surgery.
    Keywords Online graduation ; SARS-CoV-2 ; Coronavirus ; Online teaching ; Medical graduates ; Pandemic ; Medical students ; Quarantine ; covid19
    Language English
    Publishing date 2020-04-30
    Publisher University Library System, University of Pittsburgh
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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