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  1. Article ; Online: Math computerized games in the classroom: A number line training in primary school children.

    Lunardon, Maristella / Lucangeli, Daniela / Zorzi, Marco / Sella, Francesco

    Progress in brain research

    2023  Volume 276, Page(s) 1–33

    Abstract: Several studies have shown that the number line can be a useful tool to support early numeracy development. Here, we conducted a school-based training study to evaluate the effectiveness of the software "The Number Line" ("La Linea Dei Numeri"; Tressoldi ...

    Abstract Several studies have shown that the number line can be a useful tool to support early numeracy development. Here, we conducted a school-based training study to evaluate the effectiveness of the software "The Number Line" ("La Linea Dei Numeri"; Tressoldi and Peroni, 2013) in improving children's mathematical skills. We randomly allocated 10 classes of first, second and third graders (N=183) to one of three experimental groups: one group played with The Number Line; the second group played with Labyrinth, a computerized game designed to train attention skills; the third group had no intervention (business-as-usual). At the end of the first training phase, children in The Number Line group completed another training phase playing with Labyrinth, whereas the other two groups played with The Number Line. After playing with The Number Line, all groups displayed more accuracy when placing numbers in the number line task. However, we observed no evident improvement in other mathematical skills. These results suggest that specific training effects emerge even in the school context, although transfer to other numerical skills may be harder to achieve.
    MeSH term(s) Humans ; Child ; Schools ; Mathematics ; Attention ; Parent-Child Relations
    Language English
    Publishing date 2023-01-23
    Publishing country Netherlands
    Document type Journal Article
    ISSN 1875-7855 ; 0079-6123
    ISSN (online) 1875-7855
    ISSN 0079-6123
    DOI 10.1016/bs.pbr.2022.11.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Numeracy Gender Gap in STEM Higher Education: The Role of Neuroticism and Math Anxiety.

    Lunardon, Maristella / Cerni, Tania / Rumiati, Raffaella I

    Frontiers in psychology

    2022  Volume 13, Page(s) 856405

    Abstract: The under-representation of women in Science, Technology, Engineering, and Mathematics (STEM) is ubiquitous and understanding the roots of this phenomenon is mandatory to guarantee social equality and economic growth. In the present study, we ... ...

    Abstract The under-representation of women in Science, Technology, Engineering, and Mathematics (STEM) is ubiquitous and understanding the roots of this phenomenon is mandatory to guarantee social equality and economic growth. In the present study, we investigated the contribution of non-cognitive factors that usually show higher levels in females, such as math anxiety (MA) and neuroticism personality trait, to numeracy competence, a core component in STEM studies. A sample of STEM undergraduate students, balanced for gender (
    Language English
    Publishing date 2022-05-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2022.856405
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Number estimation in Down syndrome: Cognition or experience?

    Lanfranchi, Silvia / Sella, Francesco / Onnivello, Sara / Lunardon, Maristella / Zorzi, Marco

    Research in developmental disabilities

    2022  Volume 131, Page(s) 104363

    Abstract: Background: The ability to place numbers on a visual "number line" is a hallmark of the understanding of numerical magnitude and it is a strong predictor of mathematical achievement.: Aim: We examined whether the performance in the number line ... ...

    Abstract Background: The ability to place numbers on a visual "number line" is a hallmark of the understanding of numerical magnitude and it is a strong predictor of mathematical achievement.
    Aim: We examined whether the performance in the number line estimation task is more driven by mental age or experience with numbers in a sample of Italian children with Down syndrome (DS).
    Method and procedure: Sixty-three children with DS (M
    Outcomes and results: No significant differences emerged between the two groups in terms of accuracy of positioning numbers on the 1-10 and 1-20 interval. In addition, the accuracy on the 1-10 interval was related to the ability to recognize numbers, while the accuracy on the 1-20 line was related to the ability to compare magnitudes.
    Conclusion and implication: Results suggest that in individuals with DS the linear mapping of numbers is driven by mental age, but the accuracy of positioning numbers is also shaped by the experience with symbolic numbers. Therefore, the improvement of numerical estimation abilities should be a target of intervention programs.
    MeSH term(s) Child ; Humans ; Down Syndrome ; Cognition ; Mathematics ; Achievement ; Intelligence
    Language English
    Publishing date 2022-10-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639175-8
    ISSN 1873-3379 ; 0891-4222
    ISSN (online) 1873-3379
    ISSN 0891-4222
    DOI 10.1016/j.ridd.2022.104363
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Low discriminative power of WISC cognitive profile in developmental dyscalculia.

    Lunardon, Maristella / Decarli, Gisella / Sella, Francesco / Lanfranchi, Silvia / Gerola, Silvia / Cossu, Giuseppe / Zorzi, Marco

    Research in developmental disabilities

    2023  Volume 136, Page(s) 104478

    Abstract: Background: The role of domain-general cognitive abilities in the etiology of Developmental Dyscalculia (DD) is a hotly debated issue.: Aims: In the present study, we tested whether WISC-IV cognitive profiles can be useful to single out DD.: ... ...

    Abstract Background: The role of domain-general cognitive abilities in the etiology of Developmental Dyscalculia (DD) is a hotly debated issue.
    Aims: In the present study, we tested whether WISC-IV cognitive profiles can be useful to single out DD.
    Methods and procedures: Using a stringent 2-SD cutoff in a standardized numeracy battery, we identified children with DD (N = 43) within a clinical sample referred for assessment of learning disability and compared them in terms of WISC cognitive indexes to the remaining children without DD (N = 100) employing cross-validated logistic regression.
    Outcomes and results: Both groups showed higher Verbal Comprehension and Perceptual Reasoning than Working Memory and Processing Speed, and DD scores were generally lower. Predictive accuracy of WISC indexes in identifying DD individuals was low (AUC = 0.67) and it dropped to chance level in discriminating DD from selected controls (N = 43) with average math performance but matched on global IQ. The inclusion of a visuospatial memory score as an additional predictor did not improve classification accuracy.
    Conclusions and implications: These results demonstrate that cognitive profiles do not reliably discriminate DD from non-DD children, thereby weakening the appeal of domain-general accounts.
    MeSH term(s) Child ; Humans ; Dyscalculia/diagnosis ; Dyscalculia/psychology ; Learning Disabilities ; Memory, Short-Term ; Wechsler Scales ; Comprehension
    Language English
    Publishing date 2023-03-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639175-8
    ISSN 1873-3379 ; 0891-4222
    ISSN (online) 1873-3379
    ISSN 0891-4222
    DOI 10.1016/j.ridd.2023.104478
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Training basic numerical skills in children with Down syndrome using the computerized game "The Number Race".

    Sella, Francesco / Onnivello, Sara / Lunardon, Maristella / Lanfranchi, Silvia / Zorzi, Marco

    Scientific reports

    2021  Volume 11, Issue 1, Page(s) 2087

    Abstract: Individuals with Down syndrome (DS) present reduced basic numerical skills, which have a negative impact on everyday numeracy and mathematical learning. Here, we evaluated the efficacy of the adaptive (non-commercial) computerized game "The Number Race" ... ...

    Abstract Individuals with Down syndrome (DS) present reduced basic numerical skills, which have a negative impact on everyday numeracy and mathematical learning. Here, we evaluated the efficacy of the adaptive (non-commercial) computerized game "The Number Race" in improving basic numerical skills in children with DS. The experimental group (EG; N = 30, M
    MeSH term(s) Child ; Child, Preschool ; Down Syndrome/psychology ; Female ; Humans ; Male ; Mathematics ; Reading ; Video Games
    Language English
    Publishing date 2021-01-22
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-020-78801-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Parent-based training of basic number skills in children with Down syndrome using an adaptive computer game.

    Lanfranchi, Silvia / Onnivello, Sara / Lunardon, Maristella / Sella, Francesco / Zorzi, Marco

    Research in developmental disabilities

    2021  Volume 112, Page(s) 103919

    Abstract: Background: Numeracy is an area of difficulty for children with Down syndrome (DS). It has been demonstrated that The Number Race, a non-commercial adaptive computer game designed to foster basic mathematical abilities, represents a promising instrument ...

    Abstract Background: Numeracy is an area of difficulty for children with Down syndrome (DS). It has been demonstrated that The Number Race, a non-commercial adaptive computer game designed to foster basic mathematical abilities, represents a promising instrument to enhance these skills in children with DS when delivered by an expert in a clinical setting.
    Aims: In the present study, we assessed the efficacy of The Number Race when administered at home by properly instructed and remotely supervised parents.
    Methods and procedures: Basic numerical skills were assessed before and after training, as well as at three-months follow-up. Performance of children with DS who worked at home with the parent (PG) was compared with that of children who received the training by an expert (EG). For both groups, the training lasted ten weeks, with two weekly sessions of 20-30 min.
    Outcomes and results: Results show that both groups improved across various measures of numerical proficiency, including the overall score of the numeracy assessment battery, while only the EG showed an improvement in a measure of mental calculation. The improvements were maintained three months after the end of the training.
    Conclusions and implications: These findings confirm the efficacy of The Number Race and extend it to an home-based setting, whereby parents administer the training with external supervision.
    MeSH term(s) Aptitude ; Child ; Cognition ; Down Syndrome ; Humans ; Video Games
    Language English
    Publishing date 2021-03-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639175-8
    ISSN 1873-3379 ; 0891-4222
    ISSN (online) 1873-3379
    ISSN 0891-4222
    DOI 10.1016/j.ridd.2021.103919
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Catalytic Activity of Defect-Engineered Transition Me tal Dichalcogenides Mapped with Atomic-Scale Precision by Electrochemical Scanning Tunneling Microscopy.

    Lunardon, Marco / Kosmala, Tomasz / Ghorbani-Asl, Mahdi / Krasheninnikov, Arkady V / Kolekar, Sadhu / Durante, Christian / Batzill, Matthias / Agnoli, Stefano / Granozzi, Gaetano

    ACS energy letters

    2023  Volume 8, Issue 2, Page(s) 972–980

    Abstract: Unraveling structure-activity relationships is a key objective of catalysis. Unfortunately, the intrinsic complexity and structural heterogeneity of materials stand in the way of this goal, mainly because the activity measurements are area-averaged and ... ...

    Abstract Unraveling structure-activity relationships is a key objective of catalysis. Unfortunately, the intrinsic complexity and structural heterogeneity of materials stand in the way of this goal, mainly because the activity measurements are area-averaged and therefore contain information coming from different surface sites. This limitation can be surpassed by the analysis of the noise in the current of electrochemical scanning tunneling microscopy (EC-STM). Herein, we apply this strategy to investigate the catalytic activity toward the hydrogen evolution reaction of monolayer films of MoSe
    Language English
    Publishing date 2023-01-16
    Publishing country United States
    Document type Journal Article
    ISSN 2380-8195
    ISSN 2380-8195
    DOI 10.1021/acsenergylett.2c02599
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  8. Article ; Online: Production and characterization of

    Morselli, L / Donzella, A / Arzenton, A / Asti, M / Bortolussi, S / Corradetti, S / D'Agostino, G / Di Luzio, M / Ferrari, M / Gandini, A / Lunardon, M / Villa, V / Salvini, A / Zangrando, L / Zenoni, A / Andrighetto, A

    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine

    2023  Volume 197, Page(s) 110798

    Abstract: Radio Pharmaceutical Therapy (RPT) comes forth as a promising technique to treat a wide range of tumors while ensuring low collateral damage to nearby healthy tissues. This kind of cancer therapy exploits the radiation following the decay of a specific ... ...

    Abstract Radio Pharmaceutical Therapy (RPT) comes forth as a promising technique to treat a wide range of tumors while ensuring low collateral damage to nearby healthy tissues. This kind of cancer therapy exploits the radiation following the decay of a specific radionuclide to deliver a lethal dose to tumor tissues. In the framework of the ISOLPHARM project of INFN,
    MeSH term(s) Radioisotopes ; Dose-Response Relationship, Radiation ; Radiopharmaceuticals/therapeutic use ; Nuclear Reactors
    Chemical Substances Vita Mark II ; Radioisotopes ; Radiopharmaceuticals
    Language English
    Publishing date 2023-03-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 1142596-9
    ISSN 1872-9800 ; 0883-2889 ; 0969-8043
    ISSN (online) 1872-9800
    ISSN 0883-2889 ; 0969-8043
    DOI 10.1016/j.apradiso.2023.110798
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Development of implantation substrates for the collection of radionuclides of medical interest produced via ISOL technique at INFN-LNL.

    Ballan, M / Vettorato, E / Morselli, L / Tosato, M / Nardella, S / Borgna, F / Corradetti, S / Monetti, A / Lunardon, M / Zenoni, A / Di Marco, V / Realdon, N / Andrighetto, A

    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine

    2021  Volume 175, Page(s) 109795

    Abstract: Accelerator-based techniques with electromagnetic mass separation are considered among the most innovative and promising strategies to produce non-conventional radionuclides for nuclear medicine. Such approach was successfully used at CERN, where the ... ...

    Abstract Accelerator-based techniques with electromagnetic mass separation are considered among the most innovative and promising strategies to produce non-conventional radionuclides for nuclear medicine. Such approach was successfully used at CERN, where the dedicated MEDICIS facility was built, and at TRIUMF, where the ISAC radioactive beam facility was used to produce unconventional α-emitters. In such framework, the Legnaro National Laboratories of the Italian Institute of Nuclear Physics (INFN-LNL) proposed the ISOLPHARM project (ISOL technique for radioPHARMaceuticals), which will exploit radionuclides producible with the SPES (Selective Production of Exotic Species) ISOL (Isotope Separation On-Line) facility to develop novel radiopharmaceuticals. The ISOL technique utilizes the irradiation with a primary beam of particles/nuclei of a production target where radionuclides are produced. A radioactive ion beam is subsequently extracted from the production target unit, and transported up to an analyzing magnet, where non-isobaric contaminants are filtered out. The so-obtained purified radioactive beam is dumped onto an implantation substrate, referred as collection target. Then, the desired nuclides can be chemically harvested from the collected isobars, and the isotopically pure atom collection can be employed to radiolabel high specific activity radiopharmaceuticals. Metallic deposition targets in the form of coated metal foils were mostly used at TRIUMF and CERN. At ISOLPHARM, a different approach is under investigation which foresees the use of soluble cold-pressed collection targets, possibly facilitating the chemical purification process of the collected radionuclides. In this study, the production and characterization of some of the ISOLPHARM collection targets is presented, in particular, soluble salts (NaCl and NaNO3) and organic materials widely used for pharmaceutical tablets production are considered. All such materials proved to be potentially suitable as collection targets, since solid samples were easily produced and resulted compatible with the vacuum conditions required for the ion implantation process. Furthermore, some of the selected substrates were used for proof-of-concept deposition tests with stable silver, to prove their suitability as ISOLPHARM deposition substrates for silver-111, a promising candidate for radiotherapy. Such tests highlighted possible scenarios useful for the development of new alternative materials, as the use of insoluble organic targets.
    MeSH term(s) Nuclear Medicine/methods ; Radioisotopes/chemistry ; Radioisotopes/isolation & purification ; Radionuclide Imaging
    Chemical Substances Radioisotopes
    Language English
    Publishing date 2021-05-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 1142596-9
    ISSN 1872-9800 ; 0883-2889 ; 0969-8043
    ISSN (online) 1872-9800
    ISSN 0883-2889 ; 0969-8043
    DOI 10.1016/j.apradiso.2021.109795
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Biodistribution Assessment of a Novel

    Pavone, Anna Maria / Benfante, Viviana / Giaccone, Paolo / Stefano, Alessandro / Torrisi, Filippo / Russo, Vincenzo / Serafini, Davide / Richiusa, Selene / Pometti, Marco / Scopelliti, Fabrizio / Ippolito, Massimo / Giannone, Antonino Giulio / Cabibi, Daniela / Asti, Mattia / Vettorato, Elisa / Morselli, Luca / Merone, Mario / Lunardon, Marcello / Andrighetto, Alberto /
    Tuttolomondo, Antonino / Cammarata, Francesco Paolo / Verona, Marco / Marzaro, Giovanni / Mastrotto, Francesca / Parenti, Rosalba / Russo, Giorgio / Comelli, Albert

    Life (Basel, Switzerland)

    2024  Volume 14, Issue 3

    Abstract: The aim of the present study consists of the evaluation of the biodistribution of a ... ...

    Abstract The aim of the present study consists of the evaluation of the biodistribution of a novel
    Language English
    Publishing date 2024-03-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662250-6
    ISSN 2075-1729
    ISSN 2075-1729
    DOI 10.3390/life14030409
    Database MEDical Literature Analysis and Retrieval System OnLINE

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