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  1. Article ; Online: Light regularity: illuminating opportunities to enhance adolescent health.

    Lunsford-Avery, Jessica R

    Sleep

    2023  Volume 46, Issue 8

    MeSH term(s) Humans ; Adolescent ; Adolescent Health ; Sleep
    Language English
    Publishing date 2023-03-28
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 424441-2
    ISSN 1550-9109 ; 0161-8105
    ISSN (online) 1550-9109
    ISSN 0161-8105
    DOI 10.1093/sleep/zsad086
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  2. Article ; Online: CBT insomnia treatment provides insights into psychosis causes and prevention in adolescents.

    Lunsford-Avery, Jessica R

    The lancet. Psychiatry

    2023  Volume 10, Issue 9, Page(s) 657–658

    MeSH term(s) Humans ; Adolescent ; Sleep Initiation and Maintenance Disorders/therapy ; Psychotic Disorders/prevention & control ; Treatment Outcome ; Sleep
    Language English
    Publishing date 2023-08-07
    Publishing country England
    Document type Journal Article ; Comment
    ISSN 2215-0374
    ISSN (online) 2215-0374
    DOI 10.1016/S2215-0366(23)00254-7
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  3. Article ; Online: Behavioral Treatment of Insomnia and Sleep Disturbances in School-Aged Children and Adolescents.

    Lunsford-Avery, Jessica R / Bidopia, Tatyana / Jackson, Leah / Sloan, Jessica Solis

    The Psychiatric clinics of North America

    2024  Volume 47, Issue 1, Page(s) 103–120

    Abstract: Insomnia and related sleep disturbances are prevalent among youth and are associated with adverse consequences, including poorer psychiatric functioning. Behavioral sleep interventions, ranging from brief educational interventions to behavioral therapies ...

    Abstract Insomnia and related sleep disturbances are prevalent among youth and are associated with adverse consequences, including poorer psychiatric functioning. Behavioral sleep interventions, ranging from brief educational interventions to behavioral therapies (cognitive behavior therapy-insomnia), are associated with positive outcomes for pediatric sleep health. In addition, sleep interventions may improve psychiatric health for children and adolescents with neurodevelopmental and internalizing disorders. Additional research is necessary to clarify the efficacy of these interventions over the long-term and across demographic groups; however, evidence suggests incorporating behavioral sleep strategies may prove beneficial to pediatric patients with sleep disturbances and related psychiatric complaints.
    MeSH term(s) Humans ; Adolescent ; Child ; Sleep Initiation and Maintenance Disorders/therapy ; Treatment Outcome ; Behavior Therapy ; Cognitive Behavioral Therapy ; Sleep
    Language English
    Publishing date 2024-02-01
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 431518-2
    ISSN 1558-3147 ; 0193-953X
    ISSN (online) 1558-3147
    ISSN 0193-953X
    DOI 10.1016/j.psc.2023.06.007
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  4. Article ; Online: Pediatric Sleep as the Foundation for Healthy Sleep Across the Life Span.

    Baroni, Argelinda / Lunsford-Avery, Jessica R

    The Psychiatric clinics of North America

    2023  Volume 47, Issue 1, Page(s) xiii–xv

    MeSH term(s) Humans ; Child ; Longevity ; Sleep
    Language English
    Publishing date 2023-11-10
    Publishing country United States
    Document type Editorial
    ZDB-ID 431518-2
    ISSN 1558-3147 ; 0193-953X
    ISSN (online) 1558-3147
    ISSN 0193-953X
    DOI 10.1016/j.psc.2023.10.001
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  5. Article ; Online: Sleep Physiology and Neurocognition Among Adolescents With Attention-Deficit/Hyperactivity Disorder.

    Lunsford-Avery, Jessica R / Carskadon, Mary A / Kollins, Scott H / Krystal, Andrew D

    Journal of the American Academy of Child and Adolescent Psychiatry

    2024  

    Abstract: Objective: Few studies have characterized the nature of sleep problems among adolescents with attention-deficit/hyperactivity disorder (ADHD) using polysomnography (PSG). Additionally, although adolescents with ADHD and adolescents with sleep ... ...

    Abstract Objective: Few studies have characterized the nature of sleep problems among adolescents with attention-deficit/hyperactivity disorder (ADHD) using polysomnography (PSG). Additionally, although adolescents with ADHD and adolescents with sleep disturbances display similar neurocognitive deficits, the role of sleep in contributing to neurocognitive impairment in adolescent ADHD is unknown. This study investigated differences in PSG-measured sleep among adolescents with ADHD compared with non-psychiatric controls and associations with neurocognition.
    Method: Medication-free adolescents aged 13 to 17 (N = 62, n = 31 with ADHD; mean age = 15.3 years; 50% female) completed a diagnostic evaluation, 3 nights of ambulatory PSG, the Cambridge Neuropsychological Test Automated Battery, and subjective reports of sleep and executive functioning. Linear regressions covarying for age, sex, and pubertal status examined group differences in sleep indices, and partial Pearson correlations assessed relations between sleep and neurocognition.
    Results: Although adolescents with ADHD did not exhibit differences in PSG-measured sleep duration, awakenings, or latency (ps > .05) compared with non-psychiatric controls, they displayed lower slow wave sleep percentage (β = -.40) and non-rapid eye movement (NREM) electroencephalogram (EEG) delta power (β = -.29). They also exhibited greater stage 2 percentage (β = .41), NREM EEG sigma power (β = .41), and elevated self-reported sleep disturbances (ps < .05). Lower NREM EEG delta power, increased high-frequency power, and slower decline in NREM EEG delta power overnight were associated with poorer neurocognition among adolescents with ADHD.
    Conclusions: Adolescents with ADHD reported more sleep disturbances than non-psychiatric controls and exhibited differences in sleep stage distribution and NREM sleep EEG frequency. Sleep-EEG spectral indices were associated with impaired neurocognition, suggesting that physiological sleep processes may underlie neurocognitive deficits in ADHD. Future studies may clarify whether sleep plays a causal role in neurocognitive impairments in adolescent ADHD and whether interventions normalizing sleep improve neurocognition.
    Clinical trial registration information: Sleep Dysfunction and Neurocognitive Outcomes in Adolescent ADHD; https://clinicaltrials.gov/; NCT02897362.
    Diversity & inclusion statement: We worked to ensure sex and gender balance in the recruitment of human participants. We worked to ensure race, ethnic, and/or other types of diversity in the recruitment of human participants. We worked to ensure that the study questionnaires were prepared in an inclusive way. One or more of the authors of this paper self-identifies as a member of one or more historically underrepresented sexual and/or gender groups in science. We actively worked to promote sex and gender balance in our author group. While citing references scientifically relevant for this work, we also actively worked to promote sex and gender balance in our reference list.
    Language English
    Publishing date 2024-03-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 392535-3
    ISSN 1527-5418 ; 0890-8567
    ISSN (online) 1527-5418
    ISSN 0890-8567
    DOI 10.1016/j.jaac.2024.03.005
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  6. Article: Overnight Delta Dynamics Associated with Daytime Psychomotor Performance in Adults with Insomnia and Healthy Controls.

    Lunsford-Avery, Jessica R / Edinger, Jack D / Krystal, Andrew D

    Nature and science of sleep

    2022  Volume 14, Page(s) 217–230

    Abstract: Purpose: Sleep is vital to cognition, yet underlying mechanisms remain unclear. Although sleep duration and continuity are two well-established contributors, additional factors-including homeostatic sleep drive processes-may also underlie cognition- ... ...

    Abstract Purpose: Sleep is vital to cognition, yet underlying mechanisms remain unclear. Although sleep duration and continuity are two well-established contributors, additional factors-including homeostatic sleep drive processes-may also underlie cognition-related sleep restoration. This study investigates the relative contributions of sleep EEG factors to psychomotor functioning in adults with insomnia and healthy controls (HC) to identify the most significant sleep factors supporting psychomotor functioning.
    Materials and methods: Adults with insomnia (
    Results: In addition to greater wake after sleep onset (WASO;
    Conclusion: Findings suggest that, in addition to sleep duration and continuity, processes related to recovery from and dissipation of homeostatic sleep drive may support psychomotor performance and broadly support daytime functioning in individuals with and without insomnia. Future research may examine overnight delta dynamics as transdiagnostic processes supporting cognition-related sleep restoration across a range of clinical populations.
    Language English
    Publishing date 2022-02-17
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2587468-8
    ISSN 1179-1608
    ISSN 1179-1608
    DOI 10.2147/NSS.S330939
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  7. Article ; Online: Psychiatric comorbidities and prescribing tendencies of sleep medications and related medications in young people with insomnia: a United States commercial claims-based analysis.

    Bushnell, Greta / Ivanenko, Anna / Horton, Daniel B / Lunsford-Avery, Jessica R / Posner, Jonathan / Gerhard, Tobias / Suarez, Elizabeth / Olfson, Mark

    Sleep

    2024  Volume 47, Issue 5

    Abstract: Study objectives: To characterize children and youth newly diagnosed with insomnia and to describe their use of sleep and other related prescription medications.: Methods: Within a commercial claims database (January 1, 2016-December 31, 2021), we ... ...

    Abstract Study objectives: To characterize children and youth newly diagnosed with insomnia and to describe their use of sleep and other related prescription medications.
    Methods: Within a commercial claims database (January 1, 2016-December 31, 2021), we identified children and youth (2-24 years) with a newly recorded insomnia diagnosis (G47.0x; F51.0x) and examined psychiatric diagnoses in the prior 6 months. We evaluated sleep and related prescription medications dispensed in the week after new insomnia diagnoses (i.e. trazodone, other antidepressants, hydroxyzine, alpha-agonists, benzodiazepines, non-benzodiazepine hypnotics "z-drugs," antipsychotics, and others). Analyses were stratified by age and psychiatric comorbidities.
    Results: Among 68 698 children and 108 118 older youth (18-24 years) with a new insomnia diagnosis, three-quarters had a diagnosed comorbid psychiatric condition; anxiety disorders, depression, and ADHD were the most common. Among those without comorbid psychiatric diagnoses, 20.2% of children and 37.4% of older youth had a sleep or related medication dispensed in the following week. In children without a comorbid psychiatric diagnosis, alpha-agonists, hydroxyzine, and trazodone were the most common medications; in older youth, trazodone was the most common medication followed by hydroxyzine, z-drugs, and SSRIs. Sleep and related prescription medications were more commonly dispensed to those with psychiatric comorbidities. From 2017 to 2021, there was an increase in hydroxyzine prescriptions following a new insomnia diagnosis and decline in z-drug and benzodiazepine prescriptions.
    Conclusions: Our findings from a nationwide sample of young people with insomnia highlight the high prevalence of psychiatric comorbidities and variety of sleep and related medications they receive. Characterizing prescribing tendencies informs guideline development and future research.
    MeSH term(s) Humans ; Adolescent ; Sleep Initiation and Maintenance Disorders/drug therapy ; Sleep Initiation and Maintenance Disorders/epidemiology ; Male ; Female ; United States/epidemiology ; Child ; Comorbidity ; Young Adult ; Hypnotics and Sedatives/therapeutic use ; Mental Disorders/drug therapy ; Mental Disorders/epidemiology ; Trazodone/therapeutic use ; Child, Preschool ; Practice Patterns, Physicians'/statistics & numerical data ; Hydroxyzine/therapeutic use ; Antidepressive Agents/therapeutic use ; Benzodiazepines/therapeutic use ; Drug Prescriptions/statistics & numerical data
    Chemical Substances Hypnotics and Sedatives ; Trazodone (YBK48BXK30) ; Hydroxyzine (30S50YM8OG) ; Antidepressive Agents ; Benzodiazepines (12794-10-4)
    Language English
    Publishing date 2024-03-04
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 424441-2
    ISSN 1550-9109 ; 0161-8105
    ISSN (online) 1550-9109
    ISSN 0161-8105
    DOI 10.1093/sleep/zsae057
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  8. Article ; Online: Pediatric Sleep Disorders: A Unique Opportunity for Child and Adolescent Psychiatry.

    Lunsford-Avery, Jessica R / Baroni, Argelinda

    Child and adolescent psychiatric clinics of North America

    2020  Volume 30, Issue 1, Page(s) xv–xvii

    MeSH term(s) Adolescent ; Adolescent Psychiatry ; Child ; Child Psychiatry ; Family ; Humans ; Sleep Wake Disorders/diagnosis ; Sleep Wake Disorders/therapy
    Language English
    Publishing date 2020-10-27
    Publishing country United States
    Document type Editorial
    ZDB-ID 1313996-4
    ISSN 1558-0490 ; 1056-4993
    ISSN (online) 1558-0490
    ISSN 1056-4993
    DOI 10.1016/j.chc.2020.10.001
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  9. Article ; Online: The relationship between stress responding in family context and stress sensitivity with sleep dysfunction in individuals at clinical high-risk for psychosis.

    Ristanovic, Ivanka / Haase, Claudia M / Lunsford-Avery, Jessica R / Mittal, Vijay A

    Journal of psychiatric research

    2022  Volume 149, Page(s) 194–200

    Abstract: Stress and sleep have been implicated in the etiology of psychosis, and literature suggests they are closely related. Two distinct domains of stress associated with sleep dysfunction in the general population are responsivity to environmental stressors ... ...

    Abstract Stress and sleep have been implicated in the etiology of psychosis, and literature suggests they are closely related. Two distinct domains of stress associated with sleep dysfunction in the general population are responsivity to environmental stressors and stress sensitivity. However, to date, no research has examined relationships between these stress domains and sleep dysfunction in individuals at clinical high-risk (CHR) for psychosis. A total of 57 CHR (mean age = 18.89, SD = 1.82) and 61 healthy control (HC; mean age = 18.34, SD = 2.41) adolescents and young adults completed a measure of emerging stress intolerance. A subset of participants (CHR = 50, HC = 49) completed a measure indexing responsivity to family stressors - an integral context for this developmental stage overlapping with the psychosis-risk period. Sleep efficiency, continuity, and duration were objectively assessed by actigraphy (CHR = 38, HC = 36). Partial correlations with age and sex as covariates were conducted in both groups separately to examine relationships between stress and sleep. Results indicated that automatic maladaptive responsivity to family stressors was associated with disrupted sleep in the CHR but not HC group. Specifically, greater involuntary engagement was associated with poorer sleep efficiency (r = -.42) but not sleep continuity (r = 0.31) and duration (r = .-19). Interestingly, both adaptative and maladaptive voluntary responses to stressors (engagement and disengagement coping) were not associated with sleep. Finally, impaired stress tolerance was associated with sleep efficiency (r = -0.47), continuity (r = 0.37), and duration (r = -0.43). Taken together, findings provided important groundwork for understanding the role of the relationship between involuntary maladaptive responsivity to family stressors and stress sensitivity with sleep in psychosis etiology.
    MeSH term(s) Actigraphy ; Adaptation, Psychological ; Adolescent ; Humans ; Prodromal Symptoms ; Psychotic Disorders ; Sleep ; Sleep Wake Disorders/complications ; Young Adult
    Language English
    Publishing date 2022-03-02
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 3148-3
    ISSN 1879-1379 ; 0022-3956
    ISSN (online) 1879-1379
    ISSN 0022-3956
    DOI 10.1016/j.jpsychires.2022.02.038
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  10. Article ; Online: Behavioral Treatment of Insomnia and Sleep Disturbances in School-Aged Children and Adolescents.

    Lunsford-Avery, Jessica R / Bidopia, Tatyana / Jackson, Leah / Sloan, Jessica Solis

    Child and adolescent psychiatric clinics of North America

    2020  Volume 30, Issue 1, Page(s) 101–116

    Abstract: Insomnia and related sleep disturbances are prevalent among youth and are associated with adverse consequences, including poorer psychiatric functioning. Behavioral sleep interventions, ranging from brief educational interventions to behavioral therapies ...

    Abstract Insomnia and related sleep disturbances are prevalent among youth and are associated with adverse consequences, including poorer psychiatric functioning. Behavioral sleep interventions, ranging from brief educational interventions to behavioral therapies (cognitive behavior therapy-insomnia), are associated with positive outcomes for pediatric sleep health. In addition, sleep interventions may improve psychiatric health for children and adolescents with neurodevelopmental and internalizing disorders. Additional research is necessary to clarify the efficacy of these interventions over the long-term and across demographic groups; however, evidence suggests incorporating behavioral sleep strategies may prove beneficial to pediatric patients with sleep disturbances and related psychiatric complaints.
    MeSH term(s) Adolescent ; Child ; Humans ; Schools ; Sleep ; Sleep Initiation and Maintenance Disorders/therapy ; Sleep Wake Disorders/therapy ; Treatment Outcome
    Language English
    Publishing date 2020-10-21
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 1313996-4
    ISSN 1558-0490 ; 1056-4993
    ISSN (online) 1558-0490
    ISSN 1056-4993
    DOI 10.1016/j.chc.2020.08.006
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