Article: [Relationship of serum 25- hydroxy vitamin D and systemic lupus erythematosus].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences
2021 Volume 53, Issue 5, Page(s) 938–941
Abstract: Objective: To investigate the application value of serum 25-hydroxy vitamin D [25(OH)D] in systemic lupus erythematosus (SLE).: Methods: Data of 158 patients with SLE in Department of Rheumatology and Immunology in the People's Hospital of Xinjiang ... ...
Abstract | Objective: To investigate the application value of serum 25-hydroxy vitamin D [25(OH)D] in systemic lupus erythematosus (SLE). Methods: Data of 158 patients with SLE in Department of Rheumatology and Immunology in the People's Hospital of Xinjiang Uygur Autonomous Region from July 2016 to July 2019. All the SLE patients were divided into two groups by SLE scores of the disease activity index (SLEADI): 59 cases of active group (SLEADI > 4), 99 cases of non-active group (SLEDAI ≤4). Fifty healthy people were selected as healthy control group. The patients' general information and their laboratory data including serum 25(OH)D levels were collected. Statistical methods used were Results: (1) A total of 208 cases were included in this study. The level of 25(OH)D in SLE group [10.4(5.6, 15.8) μg/L] was significantly lower than that in healthy control group [25.5(22.8, 32.3) μg/L, Conclusion: The decrease of vitamin D level is related to the disease activity of SLE patients, and may be related to lupus nephritis, which plays an important role in the occurrence and development of SLE. |
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MeSH term(s) | Antibodies, Antinuclear ; Humans ; Lupus Erythematosus, Systemic ; Lupus Nephritis ; Vitamin D/analogs & derivatives |
Chemical Substances | Antibodies, Antinuclear ; Vitamin D (1406-16-2) ; 25-hydroxyvitamin D (A288AR3C9H) |
Language | Chinese |
Publishing date | 2021-10-14 |
Publishing country | China |
Document type | Journal Article |
ZDB-ID | 2452593-5 |
ISSN | 1671-167X |
ISSN | 1671-167X |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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