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  1. Article: [Relationship of serum 25- hydroxy vitamin D and systemic lupus erythematosus].

    Zou, J M / Wu, L J / Luo, C N / Shi, Y M / Wu, X

    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences

    2021  Volume 53, Issue 5, Page(s) 938–941

    Abstract: Objective: To investigate the application value of serum 25-hydroxy vitamin D [25(OH)D] in systemic lupus erythematosus (SLE).: Methods: Data of 158 patients with SLE in Department of Rheumatology and Immunology in the People's Hospital of Xinjiang ... ...

    Abstract Objective: To investigate the application value of serum 25-hydroxy vitamin D [25(OH)D] in systemic lupus erythematosus (SLE).
    Methods: Data of 158 patients with SLE in Department of Rheumatology and Immunology in the People's Hospital of Xinjiang Uygur Autonomous Region from July 2016 to July 2019. All the SLE patients were divided into two groups by SLE scores of the disease activity index (SLEADI): 59 cases of active group (SLEADI > 4), 99 cases of non-active group (SLEDAI ≤4). Fifty healthy people were selected as healthy control group. The patients' general information and their laboratory data including serum 25(OH)D levels were collected. Statistical methods used were
    Results: (1) A total of 208 cases were included in this study. The level of 25(OH)D in SLE group [10.4(5.6, 15.8) μg/L] was significantly lower than that in healthy control group [25.5(22.8, 32.3) μg/L,
    Conclusion: The decrease of vitamin D level is related to the disease activity of SLE patients, and may be related to lupus nephritis, which plays an important role in the occurrence and development of SLE.
    MeSH term(s) Antibodies, Antinuclear ; Humans ; Lupus Erythematosus, Systemic ; Lupus Nephritis ; Vitamin D/analogs & derivatives
    Chemical Substances Antibodies, Antinuclear ; Vitamin D (1406-16-2) ; 25-hydroxyvitamin D (A288AR3C9H)
    Language Chinese
    Publishing date 2021-10-14
    Publishing country China
    Document type Journal Article
    ZDB-ID 2452593-5
    ISSN 1671-167X
    ISSN 1671-167X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [Clinical features of patients with Rhupus syndrome].

    Li, Z F / Wu, X / Wu, L J / Luo, C N / Shi, Y M / Zhong, Y / Chen, X M / Meng, X Y

    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences

    2021  Volume 53, Issue 5, Page(s) 933–937

    Abstract: Objective: To investigate the clinical and serological features of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) overlap syndrome (Rhupus syndrome).: Methods: We retrospectively reviewed the medical records of 21 patients with ... ...

    Abstract Objective: To investigate the clinical and serological features of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) overlap syndrome (Rhupus syndrome).
    Methods: We retrospectively reviewed the medical records of 21 patients with Rhupus syndrome who were hospitalized at Department of Rheumatology and Immunology, People's Hospital of Xinjiang Uygur Autonomous Region between January 2010 and January 2018. We compared the joint involvement, autoantibodies and clinical manifestations of Rhupus syndrome with 81 cases of RA-alone and 51 cases of SLE-alone.
    Results: In 21 patients with Rhupus syndrome, there are 3 males and 18 females. Compared with the SLE-alone group, the patients with Rhupus syndrome were older [(49.43±11.66)
    Conclusion: Rhupus syndrome is an overlapping syndrome in which RA and SLE coexist. Most of the diseases occur in RA and the related manifestations of RA are more serious than those of SLE. The incidence of Rhupus syndrome may be related to the change of sex hormone levels.
    MeSH term(s) Adult ; Antibodies, Antinuclear ; Arthritis, Rheumatoid/complications ; Arthritis, Rheumatoid/epidemiology ; Autoantibodies ; Female ; Humans ; Lupus Erythematosus, Systemic/complications ; Lupus Erythematosus, Systemic/epidemiology ; Male ; Middle Aged ; Retrospective Studies
    Chemical Substances Antibodies, Antinuclear ; Autoantibodies
    Language Chinese
    Publishing date 2021-10-14
    Publishing country China
    Document type Journal Article
    ZDB-ID 2452593-5
    ISSN 1671-167X
    ISSN 1671-167X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: [Value of musculoskeletal ultrasound in assessing the disease activity in rheumatoid arthritis].

    Shi, Y M / Wu, L J / Wang, W J / Luo, C N / Chen, Y J

    Zhonghua yi xue za zhi

    2019  Volume 99, Issue 13, Page(s) 1008–1011

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Arthritis, Rheumatoid/diagnostic imaging ; Humans ; Retrospective Studies ; Severity of Illness Index ; Synovitis ; Ultrasonography
    Language Chinese
    Publishing date 2019-04-06
    Publishing country China
    Document type Journal Article
    ZDB-ID 132513-9
    ISSN 0376-2491
    ISSN 0376-2491
    DOI 10.3760/cma.j.issn.0376-2491.2019.13.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: [The diagnostic value of serum KL-6 in connective tissue disease associated interstitial lung disease].

    Wu, X / Wu, L J / Luo, C N / Shi, Y M / Zou, J M / Meng, X Y

    Zhonghua yi xue za zhi

    2019  Volume 99, Issue 40, Page(s) 3172–3175

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Biomarkers ; Connective Tissue Diseases/diagnosis ; Humans ; Lung Diseases, Interstitial/diagnosis ; Mucin-1/blood ; Risk Factors
    Chemical Substances Biomarkers ; MUC1 protein, human ; Mucin-1
    Language Chinese
    Publishing date 2019-11-06
    Publishing country China
    Document type Journal Article
    ZDB-ID 132513-9
    ISSN 0376-2491
    ISSN 0376-2491
    DOI 10.3760/cma.j.issn.0376-2491.2019.40.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: [Multicenter performance of the different classification criteria for rheumatoid arthritis].

    Luo, C N / Li, Z F / Wu, L J / Chen, H J / Yang, C M / Xu, W H / Liu, X L / Tang, W / Qiao, P / Rena, B

    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences

    2020  Volume 52, Issue 5, Page(s) 897–901

    Abstract: Objective: To evaluate the classification criteria of early rheumatoid arthritis (ERA) and compare the sensitivity and specificity with the criteria of 1987 American College of Rheumatology (ACR) criteria and 2010 ACR/European League Against Rheumatism ( ...

    Abstract Objective: To evaluate the classification criteria of early rheumatoid arthritis (ERA) and compare the sensitivity and specificity with the criteria of 1987 American College of Rheumatology (ACR) criteria and 2010 ACR/European League Against Rheumatism (EULAR).
    Methods: Patients from 4 hospitals, aged more than 16 years, with arthritis, whose disease duration was ≤1 year, and with ≥1 joint pain and swelling were enrolled in the study. The indicators including clinical manifestations, laboratory tests and imaging examinations were observed. The ERA patients were dignosed by two experienced rheumatologists based on the clinical features, drug therapy information and radiography features.
    Results: (1) A total of 325 patients with arthritis were enrolled, including 98 males (30.15%) and 227 females (69.85%), The average age was (47.53±14.44) years, and the median disease duration was 5 (2, 8) months. Finally, 236 patients were dignosed with ERA, and 89 patients were dignosed with other diseases (Non-ERA, including osteoarthritis, reactive arthritis, undifferentiated arthritis, spondyloarthritis, etc). (2) The sensitivity of ERA criteria was 87.29%, and the specificity was 84.37%. The sensitivity was higher than that of 1987 ACR criteria (
    Conclusion: The sensitivity of ERA classification criteria in the diagnosis of ERA was higher than that of 1987 ACR criteria, and was equivalent to that of 2010 ACR/EULAR criteria. There is no significant difference in specificity between these three criteria. The ERA criteria can also identify patients with RA at a very early stage in arthritis with disease duration ≤3 months.
    MeSH term(s) Adolescent ; Adult ; Arthritis, Rheumatoid/diagnosis ; Arthritis, Rheumatoid/diagnostic imaging ; Female ; Humans ; Male ; Middle Aged ; Osteoarthritis ; Radiography ; Rheumatology ; Sensitivity and Specificity ; United States
    Language Chinese
    Publishing date 2020-10-13
    Publishing country China
    Document type Journal Article ; Multicenter Study
    ZDB-ID 2452593-5
    ISSN 1671-167X
    ISSN 1671-167X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [The clinical significance of serum autoantibodies and HLA-B(27) molecule testing in Uygur patients with human immunodeficiency virus infection].

    Chen, X M / Luo, C N / Wu, L J / Shi, Y M / Wu, X / Meng, X Y / Lei, X / Liu, Y / Reyimujiang, Yimiti / Gulimire, Kare / Wang, T Y / Xia, F F

    Zhonghua nei ke za zhi

    2020  Volume 59, Issue 3, Page(s) 195–199

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Adult ; Anti-Citrullinated Protein Antibodies/blood ; Antibodies, Antinuclear/blood ; Antiretroviral Therapy, Highly Active ; Autoantibodies/blood ; Autoimmunity ; CD4 Lymphocyte Count ; China ; Female ; HIV Infections/blood ; HIV Infections/ethnology ; HIV Infections/immunology ; HLA-B27 Antigen/blood ; Humans ; Male ; Middle Aged ; Young Adult
    Chemical Substances Anti-Citrullinated Protein Antibodies ; Antibodies, Antinuclear ; Autoantibodies ; HLA-B27 Antigen ; anti-extractable nuclear antigen antibodies
    Language Chinese
    Publishing date 2020-03-07
    Publishing country China
    Document type Journal Article
    ZDB-ID 754223-9
    ISSN 0578-1426
    ISSN 0578-1426
    DOI 10.3760/cma.j.issn.0578-1426.2020.03.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Characterization of silencing suppressor p24 of Grapevine leafroll-associated virus 2

    Li MingJun / Zhang, J. o / Feng, M. g / Wang, X. n / Luo, C. n / Wang, Q. / Cheng, Y.

    Molecular Plant Pathology

    2018  Volume 19, Issue 2, Page(s) 355–368

    Abstract: argonaute protein; grapevine leafroll-associated virus 2; p24; RNA silencing suppressor; self-interaction. ...

    Institution Department of Pomology/Laboratory of Stress Physiology and Molecular Biology for Tree Fruits, a Key Laboratory of Beijing Municipality, China Agricultural University, Beijing 100193, China
    Abstract argonaute protein; grapevine leafroll-associated virus 2; p24; RNA silencing suppressor; self-interaction.
    Language English
    Document type Article
    ZDB-ID 2020755-4
    ISSN 1364-3703 ; 1464-6722
    ISSN (online) 1364-3703
    ISSN 1464-6722
    DOI 10.1111/mpp.12525
    Database Viticulture and Oenology Abstracts

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  8. Article: Adsorptive stripping voltammetric determination of antimony.

    Zhou, C L / Lu, Y / Li, X L / Luo, C N / Zhang, Z W / You, J M

    Talanta

    2006  Volume 46, Issue 6, Page(s) 1531–1536

    Abstract: A new method is described for the determination of antimony based on the cathodic adsorptive stripping of Sb(III) complexed with 2',3,4',5,7-pentahydroxyflavone(morin) at a static mercury drop electrode (SMDE). The reduction current of the adsorbed ... ...

    Abstract A new method is described for the determination of antimony based on the cathodic adsorptive stripping of Sb(III) complexed with 2',3,4',5,7-pentahydroxyflavone(morin) at a static mercury drop electrode (SMDE). The reduction current of the adsorbed antimony complex was measured by 1.5th-order derivative linear-sweep adsorption voltammetry. The peak potential is at -0.51 V (vs. SCE). The effects of various parameters on the response are discussed. The optimized analytical conditions were found to be: supporting electrolyte, chloroacetic acid (0.04 mol/l, pH 2.3); concentration of morin, 5x10(-6) mol/l; accumulation potential, -0.25 V (vs. SCE); scan rate, 100 mV/s. The limit of detection and the linear range were 7x10(-10) mol/l and 1.0x10(-9) approximately 3.0x10(-7) mol/l Sb(III) for a 2-min accumulation time, respectively. This method has been applied to the determination of Sb(III) in steel and brass samples and satisfactory results were obtained. The adsorptive voltammetric characteristics and composition of the Sb(III)-morin complex were studied.
    Language English
    Publishing date 2006-01-23
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1500969-5
    ISSN 1873-3573 ; 0039-9140
    ISSN (online) 1873-3573
    ISSN 0039-9140
    DOI 10.1016/s0039-9140(98)00026-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Berbamine inhibits IL-2 receptor expression, but spares IL-2 production and its mRNA expression.

    Luo, C N / Bien, Q Y / Lin, X / Wan, L W / Xiao, P G

    Phytomedicine : international journal of phytotherapy and phytopharmacology

    1998  Volume 5, Issue 4, Page(s) 269–273

    Abstract: The purpose of this paper was to elucidate the mechanism of action of berbamine on the T-lymphocyte mediated immune responses. Effects of berbamine on IL-2 production, IL-2 receptor expression and the interaction between IL-2 and IL-2 receptor were ... ...

    Abstract The purpose of this paper was to elucidate the mechanism of action of berbamine on the T-lymphocyte mediated immune responses. Effects of berbamine on IL-2 production, IL-2 receptor expression and the interaction between IL-2 and IL-2 receptor were observed. The results clearly demonstrated that berbamine suppressed the expression of IL-2 receptors on PHA induced T-blast cells, but did not alter the production of IL-2 of mouse splenic cells and human tonsil lymphocytes. Futhermore, the results also showed that berbamine at higher concentrations had a slight inhibitory effect on the interaction between IL-2 and IL-2 receptors, and addition of exogenous IL-2 did not reverse the inhibitory action of berbamine on T-cell proliferation.
    Language English
    Publishing date 1998-08
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1205240-1
    ISSN 1618-095X ; 0944-7113
    ISSN (online) 1618-095X
    ISSN 0944-7113
    DOI 10.1016/S0944-7113(98)80065-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Effect of berbamine on T-cell mediated immunity and the prevention of rejection on skin transplants in mice.

    Luo, C N / Lin, X / Li, W K / Pu, F / Wang, L W / Xie, S S / Xiao, P G

    Journal of ethnopharmacology

    1998  Volume 59, Issue 3, Page(s) 211–215

    Abstract: Berbamine, an ingredient of Berberis, which itself is widely utilized in Chinese folk-medicine has been used as a source of leukogenics, anti-arrhythmics and anti-hypertensives. In recent years, the immunosuppressive effects of berbamine has been ... ...

    Abstract Berbamine, an ingredient of Berberis, which itself is widely utilized in Chinese folk-medicine has been used as a source of leukogenics, anti-arrhythmics and anti-hypertensives. In recent years, the immunosuppressive effects of berbamine has been demonstrated. In order to further investigate the value of berbamine as an immunosuppressive agent, the delayed type hypersensitivity reaction (DTH) response with sheep red blood cells (SRBC), the mixed lymphocyte reaction (MLR) and a skin model of allograft rejection on mice were studied. Berbamine showed suppressive effects on DTH and MLR and significantly prolonged allograft survival compared with untreated transplanted mice. The results indicate that berbamine may be a potential agent in clinical transplantation.
    MeSH term(s) Alkaloids/pharmacology ; Animals ; Benzylisoquinolines ; Graft Rejection/prevention & control ; Immunity, Cellular/drug effects ; Immunosuppressive Agents/pharmacology ; Lymphocyte Culture Test, Mixed ; Medicine, Chinese Traditional ; Mice ; Plants, Medicinal/chemistry ; Skin Transplantation/immunology ; T-Lymphocytes/drug effects ; T-Lymphocytes/immunology
    Chemical Substances Alkaloids ; Benzylisoquinolines ; Immunosuppressive Agents ; berbamine (V5KM4XJ0WM)
    Language English
    Publishing date 1998-03-22
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 134511-4
    ISSN 1872-7573 ; 0378-8741
    ISSN (online) 1872-7573
    ISSN 0378-8741
    DOI 10.1016/s0378-8741(97)00117-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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