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  1. Article ; Online: Successful Recovery of a Catatonic Patient with Severe Pneumonia and Respiratory Failure: Modified Electroconvulsive Therapy Following Tracheotomy.

    Wu, Yuejing / He, Qian / Zhang, Li / Li, Tao / Luo, Fugang

    Actas espanolas de psiquiatria

    2024  Volume 52, Issue 2, Page(s) 183–188

    Abstract: Backgroud: Catatonia encompasses a group of severe psychomotor syndromes affecting patients' motor, speech, and complex behaviors. Common features include rigidity, reduced mobility, speech, sputum production, defecation, and eating. Risks associated ... ...

    Abstract Backgroud: Catatonia encompasses a group of severe psychomotor syndromes affecting patients' motor, speech, and complex behaviors. Common features include rigidity, reduced mobility, speech, sputum production, defecation, and eating. Risks associated with catatonia, such as increased muscle tension and reduced swallowing and coughing reflexes, along with risks from therapeutic approaches like prolonged bed rest and sedative drugs, can elevate the risk of aspiration pneumonia, severe pneumonia, and acute respiratory failure. These complications significantly impede catatonia treatment, leading to poor prognosis and jeopardizing patient safety.
    Case description: In this report, we present a case of catatonia complicated by severe pneumonia and respiratory failure, successfully managed with modified electroconvulsive therapy alongside tracheotomy. We hope this case provides valuable insights for psychiatrists encountering similar scenarios, facilitating the development of rational therapeutic strategies for prompt improvement of patient condition.
    MeSH term(s) Humans ; Electroconvulsive Therapy ; Tracheotomy/adverse effects ; Catatonia/therapy ; Catatonia/drug therapy ; Pneumonia/complications ; Respiratory Insufficiency/complications ; Respiratory Insufficiency/therapy
    Language English
    Publishing date 2024-04-29
    Publishing country Spain
    Document type Case Reports ; Journal Article
    ZDB-ID 1480971-0
    ISSN 1578-2735 ; 1575-071X ; 1139-9287
    ISSN (online) 1578-2735
    ISSN 1575-071X ; 1139-9287
    DOI 10.62641/aep.v52i2.1528
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: IL-6, IL-8 and IL-10 polymorphisms may impact predisposition of Alzheimer's disease: a meta-analysis.

    Yang, Rongmei / Duan, Jinfeng / Luo, Fugang / Tao, Pingyu / Hu, Chenling

    Acta neurologica Belgica

    2020  Volume 121, Issue 6, Page(s) 1505–1512

    Abstract: Gene polymorphisms in interleukin-6 (IL-6), interleukin-8 (IL-8), and interleukin-10 (IL-10) may affect the predisposition of Alzheimer's disease (AD), but the results of the so far published studies remain controversial. The authors conducted this meta- ... ...

    Abstract Gene polymorphisms in interleukin-6 (IL-6), interleukin-8 (IL-8), and interleukin-10 (IL-10) may affect the predisposition of Alzheimer's disease (AD), but the results of the so far published studies remain controversial. The authors conducted this meta-analysis to assess relationships between IL-6/IL-8/IL-10 polymorphisms and predisposition of AD by pooling the findings of so far published studies. A comprehensive search of Pubmed, Embase, Web of Science, and CNKI was endorsed by the authors to identify the already published studies. Forty-five studies were found to be eligible for meta-analyses. The pooled meta-analyses results showed that genotypic frequencies of IL-6 - 174 G/C, IL-6 - 572 G/C and IL-10 - 1082 A/G polymorphisms among patients with AD and controls differed significantly. Moreover, genotypic frequencies of IL-6 - 174 G/C, IL-6 - 572 G/C, and IL-8 - 251 A/T polymorphisms among patients with AD and controls in Asians also differed significantly. But no such genotypic frequencies' differences were observed for IL-10 - 819 C/T and 592 C/A polymorphisms. This meta-analysis suggests that IL-6 - 174 G/C, IL-6 - 572 G/C, and IL-10 - 1082 A/G polymorphisms may affect the predisposition of AD in overall population. Moreover, IL-6 - 174 G/C, IL-6 - 572 G/C, and IL-8 - 251 A/T polymorphisms may affect the predisposition of AD in Asians.
    MeSH term(s) Asians/genetics ; Genetic Predisposition to Disease/epidemiology ; Genetic Predisposition to Disease/genetics ; Humans ; Interleukin-10/genetics ; Interleukin-6/genetics ; Interleukin-8/genetics ; Polymorphism, Single Nucleotide/genetics
    Chemical Substances IL10 protein, human ; IL6 protein, human ; Interleukin-6 ; Interleukin-8 ; Interleukin-10 (130068-27-8)
    Language English
    Publishing date 2020-05-12
    Publishing country Italy
    Document type Journal Article ; Meta-Analysis
    ZDB-ID 127315-2
    ISSN 2240-2993 ; 0300-9009
    ISSN (online) 2240-2993
    ISSN 0300-9009
    DOI 10.1007/s13760-020-01369-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Effect of Non-Alcoholic Fatty Liver Disease on Estimated Glomerular Filtration Rate Could Be Dependent on Age.

    Shen, Zhe / Munker, Stefan / Luo, Fugang / Ma, Han / Yu, Chaohui / Li, Youming

    PloS one

    2015  Volume 10, Issue 6, Page(s) e0130614

    Abstract: There is a gap between the association of non-alcoholic fatty liver disease (NAFLD) and renal function in an apparently healthy population. This study aims to assess whether NAFLD is associated with estimated glomerular filtration rate (eGFR) levels and ... ...

    Abstract There is a gap between the association of non-alcoholic fatty liver disease (NAFLD) and renal function in an apparently healthy population. This study aims to assess whether NAFLD is associated with estimated glomerular filtration rate (eGFR) levels and to understand early changes of eGFR in NAFLD. A cross-sectional study was performed among apparently healthy persons who underwent general health screening including laboratory assessments and hepatic ultrasonography from January 2013 to December 2013 at the First Affiliated Hospital of Zhejiang University, College of Medicine, China. This study included 1,193 subjects with a mean age of 48 years. Prevalence of NAFLD was 31.3%. Mean eGFR was significantly lower in NAFLD than in controls (107 ± 19 mL/min/1.73 m(2) vs. 113 ± 23 mL/min/1.73 m(2), P<0.001). Correlation analysis between eGFR and NAFLD related risk factors revealed an inverse correlation between eGFR levels and some NAFLD risk factors (all P<0.01). All subjects were classified into five phases according to age. Average eGFR levels of NAFLD were lower than controls in three phases for subjects with ≤ 50 years of age (all P<0.05), while there were no significant differences on average eGFR levels between NAFLD and controls in two phases for subjects with >50 years of age (Both P>0.05). The eGFR level is significantly associated with NAFLD and its risk factors in an apparently healthy population. Effects of NAFLD on eGFR could be dependent on age.
    MeSH term(s) Adult ; Age Factors ; China/epidemiology ; Cross-Sectional Studies ; Female ; Glomerular Filtration Rate ; Humans ; Kidney/physiopathology ; Male ; Middle Aged ; Non-alcoholic Fatty Liver Disease/diagnosis ; Non-alcoholic Fatty Liver Disease/epidemiology ; Non-alcoholic Fatty Liver Disease/physiopathology ; Prevalence ; Risk Factors
    Language English
    Publishing date 2015
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0130614
    Database MEDical Literature Analysis and Retrieval System OnLINE

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