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Article ; Online: Application of Virtual Simulation Technology in Chemistry Teaching

Li Zhaoyan / Cao Yuan / Luo Jiancheng

E3S Web of Conferences, Vol 267, p

2021 Volume 02067

Abstract: Nowadays, the application of virtual simulation experiment teaching resources in universities is not systematic and comprehensive enough. Therefore, integrating professional-related virtual simulation experiment teaching resources and constructing ... ...

Abstract	Nowadays, the application of virtual simulation experiment teaching resources in universities is not systematic and comprehensive enough. Therefore, integrating professional-related virtual simulation experiment teaching resources and constructing virtual simulation comprehensive training courses can not only strengthen and expand professional knowledge and improve professional thinking but also strengthen students’ ability to realize innovative thinking. While enriching experimental teaching forms and teaching effects, virtual simulation technology also promotes the integration of experimental teaching and theoretical teaching. The article mainly discusses the application of virtual simulation technology in university chemistry teaching practice and its impact on teaching effects and then summarizes the entry point and expansion form of virtual simulation technology in the curriculum, and serves the promotion of digital and information technology in chemistry teaching application.
Keywords	Environmental sciences ; GE1-350
Subject code	370
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	EDP Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Evaluation and Optimization of Walkability of Children's School Travel Road for Accessibility and Safety Improvement.

Zhao, Jia / Su, Wei / Luo, Jiancheng / Zuo, Jin

International journal of environmental research and public health

2021 Volume 19, Issue 1

Abstract: 1) Background: In the context of a children friendly city, accessibility and safety are the basic needs of children's pedestrian school travel. This study proposes a comprehensive evaluation method of pedestrian accessibility and safety for children's ... ...

Abstract	(1) Background: In the context of a children friendly city, accessibility and safety are the basic needs of children's pedestrian school travel. This study proposes a comprehensive evaluation method of pedestrian accessibility and safety for children's school travel. (2) Methods: Firstly, the school travel network was constructed by simulating the path of children walking to school. Secondly, from the meso and micro dimensions, the impact factors of pedestrian accessibility and safety were combed out, and an evaluation index system was constructed. Finally, pedestrian accessibility and safety were evaluated based on the Space Syntax analysis and ArcGIS spatial analysis, and the results were superimposed and spatially differentiated. The new evaluation method was tested in the Jintang Road area in Hedong District, Tianjin, China. (3) Results: The pedestrian accessibility and safety of children's school travel road in the study area needed to be improved. It was found that the main impact factors were the effective walking width, the spatial connectivity, the visual integration, the obstruction of pedestrian safety, the completeness of crossing facilities and the influence of traffic flow and put forward optimization strategies. After optimized simulation verification, the overall improvement was achieved. (4) Conclusion: The evaluation method is helpful to calculate the pedestrian accessibility and safety of children's school travel, and help decision makers determine the design and management strategies of child-friendly streets.
MeSH term(s)	Accidents, Traffic/prevention & control ; Humans ; Pedestrians ; Safety ; Schools ; Walking
Language	English
Publishing date	2021-12-22
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph19010071
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: PWSC: a novel clustering method based on polynomial weight-adjusted sparse clustering for sparse biomedical data and its application in cancer subtyping.

Zhang, Xiaomeng / Zhang, Hongtao / Wang, Zhihao / Ma, Xiaofei / Luo, Jiancheng / Zhu, Yingying

BMC bioinformatics

2023 Volume 24, Issue 1, Page(s) 490

Abstract: Background: Clustering analysis is widely used to interpret biomedical data and uncover new knowledge and patterns. However, conventional clustering methods are not effective when dealing with sparse biomedical data. To overcome this limitation, we ... ...

Abstract	Background: Clustering analysis is widely used to interpret biomedical data and uncover new knowledge and patterns. However, conventional clustering methods are not effective when dealing with sparse biomedical data. To overcome this limitation, we propose a hierarchical clustering method called polynomial weight-adjusted sparse clustering (PWSC). Results: The PWSC algorithm adjusts feature weights using a polynomial function, redefines the distances between samples, and performs hierarchical clustering analysis based on these adjusted distances. Additionally, we incorporate a consensus clustering approach to determine the optimal number of classifications. This consensus approach utilizes relative change in the cumulative distribution function to identify the best number of clusters, resulting in more stable clustering results. Leveraging the PWSC algorithm, we successfully classified a cohort of gastric cancer patients, enabling categorization of patients carrying different types of altered genes. Further evaluation using Entropy showed a significant improvement (p = 2.905e-05), while using the Calinski-Harabasz index demonstrates a remarkable 100% improvement in the quality of the best classification compared to conventional algorithms. Similarly, significantly increased entropy (p = 0.0336) and comparable CHI, were observed when classifying another colorectal cancer cohort with microbial abundance. The above attempts in cancer subtyping demonstrate that PWSC is highly applicable to different types of biomedical data. To facilitate its application, we have developed a user-friendly tool that implements the PWSC algorithm, which canbe accessed at http://pwsc.aiyimed.com/ . Conclusions: PWSC addresses the limitations of conventional approaches when clustering sparse biomedical data. By adjusting feature weights and employing consensus clustering, we achieve improved clustering results compared to conventional methods. The PWSC algorithm provides a valuable tool for researchers in the field, enabling more accurate and stable clustering analysis. Its application can enhance our understanding of complex biological systems and contribute to advancements in various biomedical disciplines.
MeSH term(s)	Humans ; Algorithms ; Cluster Analysis ; Stomach Neoplasms
Language	English
Publishing date	2023-12-21
Publishing country	England
Document type	Journal Article
ZDB-ID	2041484-5
ISSN	1471-2105 ; 1471-2105
ISSN (online)	1471-2105
ISSN	1471-2105
DOI	10.1186/s12859-023-05595-4
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Optimization of FFPE preparation and identification of gene attributes associated with RNA degradation.

Lin, Yu / Dong, Zhou-Huan / Ye, Ting-Yue / Yang, Jing-Min / Xie, Mei / Luo, Jian-Cheng / Gao, Jie / Guo, An-Yuan

NAR genomics and bioinformatics

2024 Volume 6, Issue 1, Page(s) lqae008

Abstract: Formalin-fixed paraffin-embedded (FFPE) tissues are widely available specimens for clinical studies. However, RNA degradation in FFPE tissues often restricts their utility. In this study, we determined optimal FFPE preparation conditions, including ... ...

Abstract	Formalin-fixed paraffin-embedded (FFPE) tissues are widely available specimens for clinical studies. However, RNA degradation in FFPE tissues often restricts their utility. In this study, we determined optimal FFPE preparation conditions, including tissue ischemia at 4°C (<48 h) or 25°C for a short time (0.5 h), 48-h fixation at 25°C and sampling from FFPE scrolls instead of sections. Notably, we observed an increase in intronic reads and a significant change in gene rank based on expression level in the FFPE as opposed to fresh-frozen (FF) samples. Additionally, we found that more reads were mapped to genes associated with chemical stimulus in FFPE samples. Furthermore, we demonstrated that more degraded genes in FFPE samples were enriched in genes with short transcripts and high free energy. Besides, we found 40 housekeeping genes exhibited stable expression in FF and FFPE samples across various tissues. Moreover, our study showed that FFPE samples yielded comparable results to FF samples in dimensionality reduction and pathway analyses between case and control samples. Our study established the optimal conditions for FFPE preparation and identified gene attributes associated with degradation, which would provide useful clues for the utility of FFPE tissues in clinical practice and research.
Language	English
Publishing date	2024-01-31
Publishing country	England
Document type	Journal Article
ISSN	2631-9268
ISSN (online)	2631-9268
DOI	10.1093/nargab/lqae008
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Article ; Online: Competition and Cooperation among Different Attractive Forces in Solutions of Inorganic-Organic Hybrids Containing Macroionic Clusters.

Luo, Jiancheng / Liu, Tianbo

Langmuir : the ACS journal of surfaces and colloids

2019 Volume 35, Issue 24, Page(s) 7603–7616

Abstract: Hybrids composed of nanoscale inorganic clusters and organic ligands are ideal models for understanding the different attractive forces during the self-assembly processes of complex macromolecules in solution. The counterion-mediated attraction induced ... ...

Abstract	Hybrids composed of nanoscale inorganic clusters and organic ligands are ideal models for understanding the different attractive forces during the self-assembly processes of complex macromolecules in solution. The counterion-mediated attraction induced by electrostatic interaction from the large, hydrophilic macroionic clusters can compete or cooperate with other types of attractive forces such as hydrophobic interactions, hydrogen bonding, π-π stacking, and cation-π interactions from the organic ligands, consequently determining the solution behaviors of the hybrid molecules including their self-assembly process and the final supramolecular structures. The incorporation of organic ligands also leads to interesting responsive behaviors to external stimuli. Through the manipulation of the hybrid composition, architecture, topology, and solution conditions (e.g., solvent polarity, pH, and temperature), versatile self-assembled morphologies can be achieved, providing new scientific opportunities and potential applications.
Language	English
Publishing date	2019-06-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	2005937-1
ISSN	1520-5827 ; 0743-7463
ISSN (online)	1520-5827
ISSN	0743-7463
DOI	10.1021/acs.langmuir.9b00480
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Article: Competition and Cooperation among Different Attractive Forces in Solutions of Inorganic–Organic Hybrids Containing Macroionic Clusters

Luo, Jiancheng / Liu, Tianbo

Langmuir. 2019 May 22, v. 35, no. 24

2019

Abstract	Hybrids composed of nanoscale inorganic clusters and organic ligands are ideal models for understanding the different attractive forces during the self-assembly processes of complex macromolecules in solution. The counterion-mediated attraction induced by electrostatic interaction from the large, hydrophilic macroionic clusters can compete or cooperate with other types of attractive forces such as hydrophobic interactions, hydrogen bonding, π–π stacking, and cation−π interactions from the organic ligands, consequently determining the solution behaviors of the hybrid molecules including their self-assembly process and the final supramolecular structures. The incorporation of organic ligands also leads to interesting responsive behaviors to external stimuli. Through the manipulation of the hybrid composition, architecture, topology, and solution conditions (e.g., solvent polarity, pH, and temperature), versatile self-assembled morphologies can be achieved, providing new scientific opportunities and potential applications.
Keywords	electrostatic interactions ; hydrogen bonding ; hydrophilicity ; hydrophobic bonding ; ligands ; models ; pH ; solvents ; temperature ; topology
Language	English
Dates of publication	2019-0522
Size	p. 7603-7616.
Publishing place	American Chemical Society
Document type	Article
ZDB-ID	2005937-1
ISSN	1520-5827 ; 0743-7463
ISSN (online)	1520-5827
ISSN	0743-7463
DOI	10.1021/acs.langmuir.9b00480
Database	NAL-Catalogue (AGRICOLA)

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Article: Farmland parcel-based crop classification in cloudy/rainy mountains using Sentinel-1 and Sentinel-2 based deep learning

Sun, Yingwei / Li, Zhao-Liang / Luo, Jiancheng / Wu, Tianjun / Liu, Niantang

International journal of remote sensing. 2022 Feb. 01, v. 43, no. 3

2022

Abstract: Multitemporal remote sensing data, especially those for key phenological periods, play an important role in crop classification. However, cloudy/rainy climate conditions can easily lead to a lack of valid optical data, leading to crop classification ... ...

Abstract	Multitemporal remote sensing data, especially those for key phenological periods, play an important role in crop classification. However, cloudy/rainy climate conditions can easily lead to a lack of valid optical data, leading to crop classification difficulties. A general solution is taking advantage of all-weather synthetic aperture radar (SAR) datasets. In practice, SAR and optical datasets are often applied in the agricultural field by the method of image fusion, but it is difficult to apply when the number of optical images is too small. To solve this problem, this research proposes a data-transfer and feature-optimize-based method, which deploy an RNN-based encoding-decoding network to add additional data to the ‘optical’ temporal features at the farmland parcel scale and improve the utilization of optical fragments. On the basis of this method, we mitigate inconsistencies in spatial scale among different datasets and optimize the time-series parameters without expert knowledge in the crop classification procedure. The experimental results illustrate the crop classification accuracy of this method, which achieves a 4.1% improvement over the traditional approach and is especially effective for dryland crops (e.g. corn and rapeseed). Thus, this research demonstrates the effectiveness of the combined use of optical and SAR data for similar applications in cloudy/rainy mountainous areas.
Keywords	agricultural land ; arid lands ; corn ; data collection ; expert opinion ; mountains ; phenology ; rapeseed ; synthetic aperture radar ; time series analysis
Language	English
Dates of publication	2022-0201
Size	p. 1054-1073.
Publishing place	Taylor & Francis
Document type	Article
ZDB-ID	1497529-4
ISSN	1366-5901 ; 0143-1161
ISSN (online)	1366-5901
ISSN	0143-1161
DOI	10.1080/01431161.2022.2032458
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Dual-site catalysis for sustainable polymers to replace current commodity polymers - carbonylative copolymerization of ethylene, ethylene oxide, and tetrahydrofuran.

Dai, Yiwei / Luo, Jiancheng / Liu, Tianbo / Jia, Li

Chemical communications (Cambridge, England)

2020 Volume 56, Issue 97, Page(s) 15341–15344

Abstract: Zwitterionic Ni(ii)-catalyzed carbonylative copolymerization of ethylene and cyclic ethers for the synthesis of photolytically and hydrolytically degradable polymers is reported. The segmented tetrapolymer products are composed of polyketone segments ... ...

Abstract	Zwitterionic Ni(ii)-catalyzed carbonylative copolymerization of ethylene and cyclic ethers for the synthesis of photolytically and hydrolytically degradable polymers is reported. The segmented tetrapolymer products are composed of polyketone segments from alternating enchainments of CO and ethylene and poly(ether-co-ester) segments from non-alternating enchainments of CO, ethylene oxide, and tetrahydrofuran. Plastic and elastic products can be obtained via the general synthetic platform with the appropriate choice of catalyst and polymerization conditions.
Language	English
Publishing date	2020-11-24
Publishing country	England
Document type	Journal Article
ZDB-ID	1472881-3
ISSN	1364-548X ; 1359-7345 ; 0009-241X
ISSN (online)	1364-548X
ISSN	1359-7345 ; 0009-241X
DOI	10.1039/d0cc05657j
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Evaluation of Walking Comfort in Children's School Travel at Street Scale: A Case Study in Tianjin (China).

Zuo, Jin / Mu, Tong / Xiao, Tian-Yi / Luo, Jian-Cheng

International journal of environmental research and public health

2021 Volume 18, Issue 19

Abstract: 1) Background: school travel is an important part of a child's daily activities. A comfortable walking environment can encourage children to walk to school. The existing methods of evaluating walking environments are not specific to children's walks to ... ...

Abstract	(1) Background: school travel is an important part of a child's daily activities. A comfortable walking environment can encourage children to walk to school. The existing methods of evaluating walking environments are not specific to children's walks to school. (2) Methods: this study proposes a method of evaluating walking comfort in children traveling to school at street scale. Related indexes were selected that reflect children's school travel behavior and their needs in street environments based on walking environment audit tools. Factor analysis was then used to calculate the relative weight of each index. (3) Results: the new evaluation method was tested in the neighborhoods around the First Central Primary School in Hedong District, Tianjin, China. The walking comfort for children's school travel was evaluated in eight indexes: effective street width; street flatness; street cleanliness; interface diversity; buffer; shade coverage; green looking ratio; and sound decibels. Different classes and types of streets were found to have various vulnerabilities. (4) Conclusions: this evaluation method can accurately locate the weak spots in streets to improve the local policymakers' perception of street environments, which can greatly facilitate the implementation of precise measures to promote children walking to school.
MeSH term(s)	Child ; China ; Humans ; Residence Characteristics ; Schools ; Travel ; Walking
Language	English
Publishing date	2021-09-29
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph181910292
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Ductile adhesive elastomers with force-triggered ultra-high adhesion strength.

Zhao, Xiao / Demchuk, Zoriana / Tian, Jia / Luo, Jiancheng / Li, Bingrui / Cao, Ke / Sokolov, Alexei P / Hun, Diana / Saito, Tomonori / Cao, Peng-Fei

Materials horizons

2024 Volume 11, Issue 4, Page(s) 969–977

Abstract: Elastomers play a vital role in many forthcoming advanced technologies in which their adhesive properties determine materials' interface performance. Despite great success in improving the adhesive properties of elastomers, permanent adhesives tend to ... ...

Abstract	Elastomers play a vital role in many forthcoming advanced technologies in which their adhesive properties determine materials' interface performance. Despite great success in improving the adhesive properties of elastomers, permanent adhesives tend to stick to the surfaces prematurely or result in poor contact depending on the installation method. Thus, elastomers with on-demand adhesion that is not limited to being triggered by UV light or heat, which may not be practical for scenarios that do not allow an additional external source, provide a solution to various challenges in conventional adhesive elastomers. Herein, we report a novel, ready-to-use, ultra high-strength, ductile adhesive elastomer with an on-demand adhesion feature that can be easily triggered by a compression force. The precursor is mainly composed of a capsule-separated, two-component curing system. After a force-trigger and curing process, the ductile adhesive elastomer exhibits a peel strength and a lap shear strength of 1.2 × 10
Language	English
Publishing date	2024-02-19
Publishing country	England
Document type	Journal Article
ZDB-ID	2744250-0
ISSN	2051-6355 ; 2051-6347
ISSN (online)	2051-6355
ISSN	2051-6347
DOI	10.1039/d3mh01280h
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