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  1. Article ; Online: Global existence and stability of the classical solution to a density-dependent prey-predator model with indirect prey-taxis.

    Luo, Yong

    Mathematical biosciences and engineering : MBE

    2021  Volume 18, Issue 5, Page(s) 6672–6699

    Abstract: We study the existence of global unique classical solution to a density-dependent prey-predator population system with indirect prey-taxis effect. With two Lyapunov functions appropriately constructed, we then show that the solution can asymptotically ... ...

    Abstract We study the existence of global unique classical solution to a density-dependent prey-predator population system with indirect prey-taxis effect. With two Lyapunov functions appropriately constructed, we then show that the solution can asymptotically approach prey-only state or coexistence state of the system under suitable conditions. Moreover, linearized analysis on the system at these two constant steady states shows their linear instability criterion. By numerical simulation we find that some density-dependent prey-taxis and predators' diffusion may either flatten the spatial one-dimensional patterns which exist in non-density-dependent case, or break the spatial two-dimensional distribution similarity which occurs in non-density-dependent case between predators and chemoattractants (released by prey).
    MeSH term(s) Animals ; Computer Simulation ; Diffusion ; Ecosystem ; Models, Biological ; Population Dynamics ; Predatory Behavior
    Language English
    Publishing date 2021-09-13
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2265126-3
    ISSN 1551-0018 ; 1551-0018
    ISSN (online) 1551-0018
    ISSN 1551-0018
    DOI 10.3934/mbe.2021331
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Unusual case of retroperitoneal hematoma and duodenal ulcerative bleeding after nephrectomy: Case report.

    Luo, Yong / Li, Qing / Liao, Zhanchen / Luo, Zhigang

    Medicine

    2024  Volume 103, Issue 5, Page(s) e33765

    Abstract: Rationale: Retroperitoneal hematomas are relatively common in patients undergoing nephrectomy. Herein, we report an unusual case involving a giant retroperitoneal hematoma and subsequent duodenal ulcerative bleeding following a radical nephrectomy.: ... ...

    Abstract Rationale: Retroperitoneal hematomas are relatively common in patients undergoing nephrectomy. Herein, we report an unusual case involving a giant retroperitoneal hematoma and subsequent duodenal ulcerative bleeding following a radical nephrectomy.
    Patient concerns: A 77-year-old woman was admitted to our hospital for lower back pain, and she had severe right hydronephrosis and a urinary tract infection.
    Diagnoses: The patient was diagnosed and confirmed as high-grade urothelial carcinoma.
    Interventions: After ineffective conservative treatments, a right radical nephrectomy and ureteral stump resection were performed. The patient received proton pump inhibitors to prevent stress ulcer formation and bleeding. On the first day post-surgery, she had normal gastrointestinal (GI) endoscopy findings. On the second day post-surgery, abdominal computed tomography revealed a retroperitoneal hematoma. Notably, 14 days post-surgery, massive GI bleeding occurred, and GI endoscopy identified an almost perforated ulcer in the bulbar and descending duodenum.
    Outcomes: The patient died on day 15 after surgery.
    Lessons: Duodenal ulceration and bleeding might occur following a retroperitoneal hematoma in patients treated with nephrectomy. Timely intervention may prevent duodenal ulcers and complications, and thus could be a promising life-saving intercession.
    MeSH term(s) Female ; Humans ; Aged ; Ulcer/surgery ; Ulcer/complications ; Carcinoma, Transitional Cell/pathology ; Urinary Bladder Neoplasms/pathology ; Duodenum/pathology ; Gastrointestinal Hemorrhage/surgery ; Gastrointestinal Hemorrhage/complications ; Hematoma/etiology ; Hematoma/surgery ; Hematoma/diagnosis ; Duodenal Ulcer/complications ; Duodenal Ulcer/surgery ; Nephrectomy/adverse effects ; Peritoneal Diseases/surgery
    Language English
    Publishing date 2024-02-02
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000033765
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.171: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Article: Editorial: Photocatalytic functionalization of inert or unsaturated bonds.

    Luo, Yong / Zhan, Gu / Cong, Xuefeng / Zhang, Hang

    Frontiers in chemistry

    2024  Volume 12, Page(s) 1372572

    Language English
    Publishing date 2024-02-07
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2711776-5
    ISSN 2296-2646
    ISSN 2296-2646
    DOI 10.3389/fchem.2024.1372572
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Integrated phase separation in microliter droplets for ultratrace-enriching biomarker analysis.

    Zha, Qihao / Luo, Yong / Liu, Conghui / Xu, Tailin

    Lab on a chip

    2024  Volume 24, Issue 6, Page(s) 1775–1781

    Abstract: Ultratrace-enriching biomarker analysis is an effective method for achieving highly accurate and enhanced sensitive detection. In this study, we have developed an enrichment detection platform by combining a minipillar array with an aqueous two-phase ... ...

    Abstract Ultratrace-enriching biomarker analysis is an effective method for achieving highly accurate and enhanced sensitive detection. In this study, we have developed an enrichment detection platform by combining a minipillar array with an aqueous two-phase system (ATPS) for ultratrace enriching biomarker analysis. After optimizing the enrichment conditions of ATPS, target miRNAs at ultratrace levels specifically accumulate in the DEX-rich phase, which significantly increases the target miRNA concentration-related fluorescence intensity. Compared to non-enriched miRNA in the single-phase PEG solution, the detection limit of ATPS-enriched miRNA had improved more than 200-fold. The ATPS-based enrichment detection strategy offers a novel and convenient approach for the simultaneous detection of biomarkers with ultratrace.
    MeSH term(s) Phase Separation ; MicroRNAs ; Biomarkers ; Polyethylene Glycols
    Chemical Substances MicroRNAs ; Biomarkers ; Polyethylene Glycols (3WJQ0SDW1A)
    Language English
    Publishing date 2024-03-12
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2056646-3
    ISSN 1473-0189 ; 1473-0197
    ISSN (online) 1473-0189
    ISSN 1473-0197
    DOI 10.1039/d3lc00953j
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Identification of a Necroptosis-Related Prognostic Index and Associated Regulatory Axis in Kidney Renal Clear Cell Carcinoma.

    Luo, Yong / Zhang, Guian

    International journal of general medicine

    2022  Volume 15, Page(s) 5407–5423

    Abstract: Background: Kidney renal clear cell carcinoma (KIRC) is one of the most common aggressive malignancies in the genitourinary system with the high degree of immune infiltration. However, the role of necroptosis-related genes in the immune infiltration of ... ...

    Abstract Background: Kidney renal clear cell carcinoma (KIRC) is one of the most common aggressive malignancies in the genitourinary system with the high degree of immune infiltration. However, the role of necroptosis-related genes in the immune infiltration of KIRC and the impact on overall survival have not been adequately studied.
    Methods: Differentially expressed necroptosis-related genes were identified based on The Cancer Genome Atlas (TCGA). Then, we constructed a necroptosis-related prognostic index (NRPI) through Lasso Cox regression analysis. The KIRC patients were divided into NRPI-high and NRPI-low groups by the median. Univariate and multivariate Cox regression analyses were used to determine NRPI as an independent prognostic factor. The role of NRPI was assessed through nomogram, GO/KEGG enrichment analyses, and immune cells infiltration. The efficacy of immunotherapy in KIRC patients was evaluated by TIDE. The immunohistochemistry was performed to verify the difference in protein expression between tumor samples and normal tissues from our hospital.
    Results: We found that NRPI-high patients had higher mortality. The multivariate Cox regression between the signature and multiple clinicopathological characteristics proved that NRPI could effectively and independently predict the prognosis of KIRC. The protein expression of three necroptosis-related genes constituting NRPI was significantly different between tumor and normal tissues. NRPI was closely related to immunologically relevant pathways and functions. The tumor microenvironment and immune infiltrating cells showed clear distinctions in NRPI-high and NRPI-low patients. The analysis of clinical treatments found that NRPI-low patients responded better to immunotherapy, while NRPI-high patients were more sensitive to targeted therapy. Furthermore, we identified a lncRNAs/miRNA/mRNA regulatory axis for KIRC.
    Conclusion: In general, NRPI was a promising biomarker in predicting the prognosis and responses to treatments in KIRC.
    Language English
    Publishing date 2022-06-03
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2452220-X
    ISSN 1178-7074
    ISSN 1178-7074
    DOI 10.2147/IJGM.S367173
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Circular RNA PVT1 promotes progression of thyroid cancer by competitively binding miR-384.

    Hua, Tebo / Luo, Yong

    Experimental and therapeutic medicine

    2022  Volume 24, Issue 4, Page(s) 629

    Abstract: Plasmacytoma variant translocation 1 circular RNA (circPVT1) is involved in the initiation and development of several types of cancer. However, the underlying molecular role of circPVT1 in tumorigenesis of thyroid cancer remains to be elucidated. In the ... ...

    Abstract Plasmacytoma variant translocation 1 circular RNA (circPVT1) is involved in the initiation and development of several types of cancer. However, the underlying molecular role of circPVT1 in tumorigenesis of thyroid cancer remains to be elucidated. In the present study, relative expression of circPVT1 was markedly upregulated in thyroid cancer compared with adjacent normal tissue. circPVT1 expression was associated with clinical stage and lymph node metastasis. Furthermore, Cell Counting Kit-8, colony formation and Transwell chamber assays demonstrated that knockdown of circPVT1 decreased proliferation, migration and invasion of thyroid cancer cells
    Language English
    Publishing date 2022-08-19
    Publishing country Greece
    Document type Journal Article
    ZDB-ID 2683844-8
    ISSN 1792-1015 ; 1792-0981
    ISSN (online) 1792-1015
    ISSN 1792-0981
    DOI 10.3892/etm.2022.11566
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Influence of water on mechanical behavior of surrounding rock in hard-rock tunnels: An experimental simulation

    Luo, Yong

    Engineering geology. 2020 Nov., v. 277

    2020  

    Abstract: To investigate the influence of water on the mechanical behavior of rock surrounding hard-rock tunnels, a series of uniaxial and true-triaxial compression tests were performed on red sandstone samples with two different water contents (natural water ... ...

    Abstract To investigate the influence of water on the mechanical behavior of rock surrounding hard-rock tunnels, a series of uniaxial and true-triaxial compression tests were performed on red sandstone samples with two different water contents (natural water content (NWC) and saturated water content (SWC)). The samples taken were cubic samples containing a circular hole and cylindrical samples. During the true-triaxial tests, hole failure was monitored and recorded in real-time with in-house developed monitoring equipment. The effects of water on the stress, energy, and fracture characteristics of rock failure in hard-rock tunnel were determined. The results indicate that, after reaching the SWC state, the strength and elastic modulus of red sandstone were reduced, and the shear characteristics became more obvious. The failure mode of the NWC holes was primarily slab ejection, while the failure mode of the SWC holes was primarily slab flaking. Water changes the mesoscopic mechanism of spalling and exhibits a double effect on hard-rock tunnels. The mechanisms of water on rockburst prevention are to reduce residual elastic strain energy, avoid excessive concentration of strain energy, and increase rockburst resistance. The ratio of the far-field maximum principal stress to the uniaxial compressive strength can be used as an index to evaluate the stability of hard-rock tunnels. The results help to rethink the influence of water on underground hard rock engineering, such as the failure mechanism of surrounding rock and the analysis of tunnel (or caverns) stability in water-rich stratum, and the mechanism of water on the rockburst prevention.
    Keywords compression strength ; energy ; equipment ; mechanical properties ; modulus of elasticity ; sandstone ; water content
    Language English
    Dates of publication 2020-11
    Publishing place Elsevier B.V.
    Document type Article
    Note NAL-AP-2-clean
    ISSN 0013-7952
    DOI 10.1016/j.enggeo.2020.105816
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: A New Strategy for the Regulation of Neuroinflammation: Exosomes Derived from Mesenchymal Stem Cells.

    Ge, Ying / Wu, Jingjing / Zhang, Li / Huang, Nanqu / Luo, Yong

    Cellular and molecular neurobiology

    2024  Volume 44, Issue 1, Page(s) 24

    Abstract: Neuroinflammation is an important pathogenesis of neurological diseases and causes a series of physiopathological changes, such as abnormal activation of glial cells, neuronal degeneration and death, and disruption of the blood‒brain barrier. Therefore, ... ...

    Abstract Neuroinflammation is an important pathogenesis of neurological diseases and causes a series of physiopathological changes, such as abnormal activation of glial cells, neuronal degeneration and death, and disruption of the blood‒brain barrier. Therefore, modulating inflammation may be an important therapeutic tool for treating neurological diseases. Mesenchymal stem cells (MSCs), as pluripotent stem cells, have great therapeutic potential for neurological diseases due to their regenerative ability, immunity, and ability to regulate inflammation. However, recent studies have shown that MSC-derived exosomes (MSC-Exos) play a major role in this process and play a key role in neuroprotection by regulating neuroglia. This review summarizes the recent progress made in regulating neuroinflammation by focusing on the mechanisms by which MSC-Exos are involved in the regulation of glial cells through signaling pathways such as the TLR, NF-κB, MAPK, STAT, and NLRP3 pathways to provide some references for subsequent research and therapy.
    MeSH term(s) Humans ; Neuroinflammatory Diseases ; Exosomes ; Inflammation ; Mesenchymal Stem Cells ; Blood-Brain Barrier
    Language English
    Publishing date 2024-02-19
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 283404-2
    ISSN 1573-6830 ; 0272-4340
    ISSN (online) 1573-6830
    ISSN 0272-4340
    DOI 10.1007/s10571-024-01460-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1727: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article: Survey on Latent Infection of Canker-Causing Pathogens in Budwood and Young Trees from Almond and Prune Nurseries in California.

    Luo, Yong / Niederholzer, Franz / Camiletti, Boris X / Michailides, Themis J

    Plant disease

    2024  Volume 108, Issue 3, Page(s) 550–557

    Abstract: Almond band canker and prune Cytospora canker have become more severe in the last decade, especially in young orchards, in California. To test our hypothesis that young trees from nurseries could carry the canker-causing pathogens at latency phase to new ...

    Abstract Almond band canker and prune Cytospora canker have become more severe in the last decade, especially in young orchards, in California. To test our hypothesis that young trees from nurseries could carry the canker-causing pathogens at latency phase to new orchards through transplanting, a multiyear survey on latent infection of canker-causing pathogens of budwood and young trees of almond and prune nurseries in California was conducted. A total of more than 1,730 samples including shoots of rootstocks and scions and grafting union cuttings were collected from 11 nurseries. A real-time quantitative PCR assay was applied to quantify the latent infection levels by six canker-causing pathogen taxa:
    MeSH term(s) Humans ; Prunus dulcis/genetics ; Trees ; Nurseries, Infant ; Plant Diseases ; California
    Language English
    Publishing date 2024-02-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 754182-x
    ISSN 0191-2917
    ISSN 0191-2917
    DOI 10.1094/PDIS-07-23-1449-SR
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 2043: Show issues

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  10. Article: Neuroprotective effect of tanshinone IIA-modified mesenchymal stem cells in a lipopolysaccharide-induced neuroinflammation model.

    Wu, Jingjing / Chen, Jian / Ge, Ying / Huang, Nanqu / Luo, Yong

    Heliyon

    2024  Volume 10, Issue 8, Page(s) e29424

    Abstract: In this study, the neuroprotective potential of tanshinone IIA (TIIA)-modified mesenchymal stem cells (MSC) were investigated using a murine model of lipopolysaccharide (LPS)-induced neuroinflammation. The cognitive performance of the mice was assessed ... ...

    Abstract In this study, the neuroprotective potential of tanshinone IIA (TIIA)-modified mesenchymal stem cells (MSC) were investigated using a murine model of lipopolysaccharide (LPS)-induced neuroinflammation. The cognitive performance of the mice was assessed using the Y-maze and Morris water maze tests, while immunofluorescence and Western blot analyses were employed to evaluate the hippocampal expression of pertinent markers and inflammatory factors, respectively. The results from the behavioral experiments demonstrated discernible differences in learning and memory abilities between the model group and the control group (
    Language English
    Publishing date 2024-04-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e29424
    Database MEDical Literature Analysis and Retrieval System OnLINE

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