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  1. Article ; Online: Bayesian-Based Probabilistic Risk Assessment of Fipronil in Food: A Case Study in Taiwan.

    Luo, Yu-Syuan

    Toxics

    2023  Volume 11, Issue 8

    Abstract: Fipronil, a broad-spectrum insecticide, is widely used in agriculture and veterinary practices. Fipronil-induced neurotoxicity and potential adverse effects on humans and aquatic organisms have raised health concerns. Monitoring programs have been ... ...

    Abstract Fipronil, a broad-spectrum insecticide, is widely used in agriculture and veterinary practices. Fipronil-induced neurotoxicity and potential adverse effects on humans and aquatic organisms have raised health concerns. Monitoring programs have been implemented globally to assess fipronil residues in food, including fruits, vegetables, and animal products. However, previous exposure assessments have often focused on specific food categories or subsets of items, resulting in limited insights into the overall health risks. Additionally, the large number of non-detect fipronil residues in food has introduced uncertainties in exposure assessment. To address these issues, a probabilistic exposure assessment and dose-response analysis were adopted in this study, considering the sample distribution below the detection limit to better characterize uncertainties and population variability in health risk assessments. The estimated fipronil exposure to the general public ranges from 6.38 × 10
    Language English
    Publishing date 2023-08-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2733883-6
    ISSN 2305-6304 ; 2305-6304
    ISSN (online) 2305-6304
    ISSN 2305-6304
    DOI 10.3390/toxics11080677
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Indian monsoon drove the dispersal of the

    Luo, Yu-Fa / Li, Shu-Qiang

    Zoological research

    2024  Volume 45, Issue 1, Page(s) 152–159

    Abstract: We examined the global biogeography of ... ...

    Abstract We examined the global biogeography of the
    MeSH term(s) Animals ; Spiders/genetics
    Language English
    Publishing date 2024-02-07
    Publishing country China
    Document type Journal Article
    ISSN 2095-8137
    ISSN 2095-8137
    DOI 10.24272/j.issn.2095-8137.2023.364
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: [Current Situation and Advances in Diagnosing Triple-negative Breast Cancer Using Ultrasound].

    Luo, Yu-Kun

    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae

    2021  Volume 43, Issue 3, Page(s) 309–313

    Abstract: Triple-negative breast cancer is a complex type of breast cancer,the most common malignant tumor in women.Since the early image features of triple-negative breast cancer appear benign tumor with rapid growth,this cancer has progressed into the middle and ...

    Abstract Triple-negative breast cancer is a complex type of breast cancer,the most common malignant tumor in women.Since the early image features of triple-negative breast cancer appear benign tumor with rapid growth,this cancer has progressed into the middle and late stages once diagnosed,which leads to high mortality.Therefore,the diagnosis of triple-negative breast cancer has always been a clinical difficulty.This article summarizes the role of ultrasound in the diagnosis and treatment of triple-negative breast cancer.The extracted multi-mode ultrasound features will facilitate the early detection of this cancer and improve the prognosis of these patients.
    Language Chinese
    Publishing date 2021-06-21
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 604853-5
    ISSN 1000-503X
    ISSN 1000-503X
    DOI 10.3881/j.issn.1000-503X.13917
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Protocol for the Generation of Human EPS-Blastoids Using a Three-Dimensional Two-Step Induction System.

    Luo, Yu-Xin / Yu, Yang

    Methods in molecular biology (Clifton, N.J.)

    2023  Volume 2767, Page(s) 27–41

    Abstract: Stem cell-derived embryos in vitro allow the exploration of the very early stages of human embryogenesis in vitro and are thus promising for widespread applications in developmental biology, related developmental disease modeling, and drug discovery. ... ...

    Abstract Stem cell-derived embryos in vitro allow the exploration of the very early stages of human embryogenesis in vitro and are thus promising for widespread applications in developmental biology, related developmental disease modeling, and drug discovery. Several cell resources have been utilized, with different efficiencies and methods for generating human blastoids, a structure similar to natural blastocysts. Human EPS cells were reported to contribute to the embryonic and extraembryonic lineages and therefore can be a practical and efficient cell resource for constructing human blastoids. Here, we developed a three-dimensional, two-step induction system for generating human blastoids using human EPS cells. According to morphological and transcriptomic analysis, EPS-blastoids recapitulate the key developmental processes and cell lineages of human blastocysts. Moreover, in vitro extended culture for 8 and 10 days of EPS-blastoids can result in postimplantation embryonic structures. In this chapter, we describe a protocol that covers the generation, maintenance, and developmental phenocopying of human EPS blastoids.
    MeSH term(s) Humans ; Blastocyst ; Embryo, Mammalian ; Cell Lineage ; Stem Cells ; Gene Expression Profiling
    Language English
    Publishing date 2023-02-06
    Publishing country United States
    Document type Journal Article
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/7651_2022_471
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Light People: Prof. Sir John Pendry, father of metamaterials, spoke about the future of meta.

    Guo, Chenzi / Luo, Yu

    Light, science & applications

    2023  Volume 12, Issue 1, Page(s) 45

    Abstract: Editorial: When consulting with the Marconi company in 1995, Prof. Sir John Pendry uncovered exotic structures that gave negative permittivity and negative permeability, respectively. In 1999, Prof. Pendry introduced split ring resonators (SRRs), and ... ...

    Abstract Editorial: When consulting with the Marconi company in 1995, Prof. Sir John Pendry uncovered exotic structures that gave negative permittivity and negative permeability, respectively. In 1999, Prof. Pendry introduced split ring resonators (SRRs), and later in 2000, Prof. David Smith and Prof. Sheldon Schultz experimentally showed that periodic array of SRRs and continuous wires previously proposed by Prof. Pendry could exhibit simultaneously negative values of effective permeability and permittivity at the same frequency. Shortly after, Prof. Pendry revealed that a slab of material with simultaneous negative permittivity and permeability could challenge the Abbé diffraction limit on traditional lenses and focus all Fourier components of a point object onto a perfect image, leading to a "perfect lens". The vision of a perfect lens attracted extensive research interest and opened a new field which was later widely known as metamaterials. Now two decades on, the explosion of metamaterials has revolutionized numerous researches in physics, materials science, chemistry, and engineering. To shed light on the research direction of metamaterials, Light: Science & Applications invited Sir John Pendry, father and living legend of metamaterials, to speak about the future of metamaterials. The original interview can be accessed in Supplementary video.
    Language English
    Publishing date 2023-02-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 2662628-7
    ISSN 2047-7538 ; 2047-7538
    ISSN (online) 2047-7538
    ISSN 2047-7538
    DOI 10.1038/s41377-023-01082-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The Role of Nucleoporins in Cardiac Tissue Development and Disease.

    Chen, Xiaocong / Shi, Rui / Luo, Yu / Xu, Liang

    Frontiers in bioscience (Landmark edition)

    2024  Volume 28, Issue 12, Page(s) 350

    Abstract: Nuclear pore complexes (NPCs) are intricate intracellular structures composed of approximately 30 nuclear pore proteins (NUPs) that regulate the transport of materials between the nucleus and cytoplasm in eukaryotic cells. The heart is a crucial organ ... ...

    Abstract Nuclear pore complexes (NPCs) are intricate intracellular structures composed of approximately 30 nuclear pore proteins (NUPs) that regulate the transport of materials between the nucleus and cytoplasm in eukaryotic cells. The heart is a crucial organ for sustaining the vital functions of the body, pumping blood rich in nutrients and energy to all organs and tissues. Recent studies have shown that NPCs play pivotal roles not only in normal cardiac physiological processes such as myocardial cell proliferation and differentiation but also in various pathological processes such as ischemic and hypoxic myocardial injury. Due to their mass and complicated nature, the structures of NPCs have been challenging to identify by the scientific community. With the development of cryo-electron microscopy and advanced sampling techniques, researchers have made significant progress in understanding the structures of NPCs. This review aims to summarize the latest research on the structural aspects of NPCs and their roles in cardiac physiology and pathology, increase the understanding of the intricate mechanisms of NPC actions, provide valuable insights into the pathogenesis of heart diseases and describe the development of potential novel therapeutic strategies.
    MeSH term(s) Nuclear Pore Complex Proteins/analysis ; Nuclear Pore Complex Proteins/chemistry ; Nuclear Pore Complex Proteins/metabolism ; Active Transport, Cell Nucleus/physiology ; Cryoelectron Microscopy ; Nuclear Pore/chemistry ; Nuclear Pore/metabolism ; Cytoplasm/metabolism
    Chemical Substances Nuclear Pore Complex Proteins
    Language English
    Publishing date 2024-01-04
    Publishing country Singapore
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2704569-9
    ISSN 2768-6698 ; 2768-6698
    ISSN (online) 2768-6698
    ISSN 2768-6698
    DOI 10.31083/j.fbl2812350
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Exosome-derived lncRNA A1BG-AS1 attenuates the progression of prostate cancer depending on ZC3H13-mediated m6A modification.

    Yang, Zhi / Luo, Yu / Zhang, Fan / Ma, Likun

    Cell division

    2024  Volume 19, Issue 1, Page(s) 5

    Abstract: Background: Exosome-derived long non-coding RNAs (lncRNAs) and N6-methyladenosine (m: Methods: PCa cell exosomes were extracted, exosomal marker proteins (CD63, CD9) were detected utilizing western blotting, and exosomes with overexpressing A1BG-AS1 ... ...

    Abstract Background: Exosome-derived long non-coding RNAs (lncRNAs) and N6-methyladenosine (m
    Methods: PCa cell exosomes were extracted, exosomal marker proteins (CD63, CD9) were detected utilizing western blotting, and exosomes with overexpressing A1BG-AS1 were co-cultured with targeted PCa cells. qRT-PCR was used to detect A1BG-AS1 expression and m
    Results: We observed that A1BG-AS1 and ZC3H13 expression was restricted in PCa tumors. The invasion, proliferation and migratory capacities of PCa cells could be inhibited by up-regulating A1BG-AS1 or by co-culturing with exosomes that up-regulate A1BG-AS1. Additionally, ZC3H13 promoted stable A1BG-AS1 expression by regulating the m
    Conclusion: Exosomal A1BG-AS1 was m
    Language English
    Publishing date 2024-02-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 2236097-9
    ISSN 1747-1028
    ISSN 1747-1028
    DOI 10.1186/s13008-024-00110-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Using behavioral interventions to reduce single-use produce bags

    Luo, Yu / Zhao, Jiaying

    Resources, Conservation & Recycling. 2023 June, v. 193 p.106942-

    2023  

    Abstract: Plastic pollution is a major conservation challenge. Current policies have primarily focused on plastic bags but neglected produce bags which are a pervasive source of packaging in grocery stores. To reduce produce bag use, we designed and tested 12 ... ...

    Abstract Plastic pollution is a major conservation challenge. Current policies have primarily focused on plastic bags but neglected produce bags which are a pervasive source of packaging in grocery stores. To reduce produce bag use, we designed and tested 12 behavioral interventions in a simulated online shopping task. Each intervention reduced produce bag use by 9.2% to 48.7% against the control condition. Among the 12, the most effective interventions included using an indirect incentive or punishment (via donations to an environmental organization), reminding people of the positive consequence of not using produce bags, using normative messaging, drawing attention to the no produce bag option, and reminding or visualizing the negative consequence of using produce bags. These interventions were more effective for liberal participants than conservatives or independents. These findings provide new evidence for effective behavioral interventions and heterogenous effects in encouraging people to reduce produce bag use to curb plastic pollution.
    Keywords design ; e-commerce ; grocery stores ; issues and policy ; organizations ; packaging ; people ; plastic bags ; pollution ; recycling ; testing ; Plastic pollution ; Behavior change ; Nudge ; Sludge ; Experiments
    Language English
    Dates of publication 2023-06
    Publishing place Elsevier B.V.
    Document type Article ; Online
    ZDB-ID 1498716-8
    ISSN 0921-3449
    ISSN 0921-3449
    DOI 10.1016/j.resconrec.2023.106942
    Database NAL-Catalogue (AGRICOLA)

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  9. Article ; Online: How to cushion economic recession caused by the COVID-19 pandemic: Fiscal or monetary policies?

    Wu, Ya / Luo, Yu

    Frontiers in public health

    2022  Volume 10, Page(s) 960655

    Abstract: The outbreak of the COVID-19 pandemic has brought the global economy to a crisis: how to choose the optimal policy tools to cope with the external impacts has attracted worldwide attention. The research evaluates the effects of China's fiscal and ... ...

    Abstract The outbreak of the COVID-19 pandemic has brought the global economy to a crisis: how to choose the optimal policy tools to cope with the external impacts has attracted worldwide attention. The research evaluates the effects of China's fiscal and monetary policies in promoting economic recovery by establishing a CGE model. Five representative countermeasures such as exempting value-added tax (VAT) and cutting loan rates are studied. The results indicate that: from the aspect of fiscal policies, increasing investment shows a better effect in boosting economy compared with exempting VAT and increasing medical care expenditures; however, the policy also causes price inflation (+0.45%) and crowding-out of enterprise investment (-0.03%). From the aspect of monetary policies, providing targeted loans to enterprises has a better boosting effect on economy compared with cutting loan rates. In the choice between fiscal or monetary policies, fiscal policies exert better effects (household income, +0.95%) when taking the improvement of residents' welfare as the objective. If taking promoting recovery of enterprises and boosting the economy as objectives, monetary policies are found to be better (GDP, +1.99%). Therefore, fiscal and monetary policies should be guided by different objectives and allowed to work in a synergistic manner.
    MeSH term(s) Humans ; Economic Recession ; COVID-19/epidemiology ; Pandemics ; Policy
    Language English
    Publishing date 2022-10-28
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2022.960655
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Association Between Germline

    Luo, Yu / Pan, Ru / Rao, Hui / Chen, Xing / Yang, Haikun

    International journal of general medicine

    2024  Volume 17, Page(s) 75–84

    Abstract: Objective: To investigate the relationship between : Methods: Patients diagnosed with ovarian cancer between January 2018 and July 2023 who underwent : Results: A total of 284 ovarian cancer patients were collected, and the subjects were divided ... ...

    Abstract Objective: To investigate the relationship between
    Methods: Patients diagnosed with ovarian cancer between January 2018 and July 2023 who underwent
    Results: A total of 284 ovarian cancer patients were collected, and the subjects were divided into two groups, 197 non-carriers and 87
    Conclusion: Patients with
    Language English
    Publishing date 2024-01-11
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2452220-X
    ISSN 1178-7074
    ISSN 1178-7074
    DOI 10.2147/IJGM.S445660
    Database MEDical Literature Analysis and Retrieval System OnLINE

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