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Article: Health persuasion through emoji: How emoji interacted with information source to predict health behaviors in COVID-19 situation.

Lin, Tingyi S / Luo, Yue

SSM - population health

2023 Volume 21, Page(s) 101343

Abstract: By providing health information through visual communication, public health organizations can effectively guide and persuade people to adopt healthy behaviors, which is critical in the context of public health crises. In this study, drawing upon ... ...

Abstract	By providing health information through visual communication, public health organizations can effectively guide and persuade people to adopt healthy behaviors, which is critical in the context of public health crises. In this study, drawing upon congruity theory and the premise of visual communication, we examined how information source and emoji may shape people's preventive and self-protective behaviors through perceived fear (PF) and perceived controllability (PC). Using a convenience sample of 210 participants, we conducted a 2 (emoji: with versus without) × 2 (information source: official versus unofficial) between-subject experiment. The results indicated that, compared with nonuse, the use of emoji in information resulted in higher PF, stronger preventive behavioral intention (PBI), and lower PC. In addition, a strong interaction effect was observed between emoji and the source of information on PBI. When emoji were added to health information released by an unofficial organization, the text outperformed that from an official agency in persuading people to adopt preventive behaviors. Furthermore, we determined that PF mediated the effect of emoji on PBI, but only for unofficial information sources. These results provide a reference for enhancing the effectiveness of health information including visual cues, such as emoji.
Language	English
Publishing date	2023-01-21
Publishing country	England
Document type	Journal Article
ISSN	2352-8273
ISSN	2352-8273
DOI	10.1016/j.ssmph.2023.101343
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Article ; Online: Management of Venous Access Port to Overcome Kinesiophobia of Patients with Malignant Tumors: A Review.

Duan, Wei / Gu, Hanna / Luo, Yue / Li, Wei

Medical science monitor : international medical journal of experimental and clinical research

2024 Volume 30, Page(s) e943181

Abstract: The number of patients with malignant tumors is increasing in China, and venous access ports have unique advantages for chemotherapy. Currently, China's research on venous access port-mediated kinesiophobia is still in the developing stage. Using the ... ...

Abstract	The number of patients with malignant tumors is increasing in China, and venous access ports have unique advantages for chemotherapy. Currently, China's research on venous access port-mediated kinesiophobia is still in the developing stage. Using the combination of subjective words and freedom words, and based on literature traceability methods, China National Knowledge Infrastructure (CNKI), Wanfang, Vipp, Chinese Biomedical Database (CBM), Web of Science, The COCHRANE LIBRARY, Embase, and PubMed were searched. Relevant articles published from the construction of the database to October 30, 2023, were identified. Based on the many articles and analyses, the methods of assessing kinesiophobia in malignant tumors patients using venous access port, the related influencing factors and the preventive and intervention strategies were collated. We found 33 articles examining kinesiophobia in oncology patients, of which 4 were specifically conducted on patients with malignant tumors using VAPs or PICCs. The relevant preventive and therapeutic experiences regarding kinesiophobia in cancer patients with VAP still need improvement. Nursing staff can use assessment tools such as the Tampa Rating Scale for Kinesiophobia, the Fear Avoidance Beliefs Questionnaire, and the Cancer Fatigue Scale to reasonably and effectively assess kinesiophobia among patients with malignant tumors who use VAPs. Attention should be paid to the mechanisms and roles of demographic factors, pain and foreign body sensation, cancer fatigue, pain management strategies, and other factors influencing kinesiophobia. This study provides advice to nursing staff for the management of VAP. Such considerations may reduce the complications of kinesiophobia and improve the quality of life of patients.
MeSH term(s)	Humans ; Kinesiophobia ; Quality of Life ; Catheterization, Central Venous ; Neoplasms/complications ; Fatigue
Language	English
Publishing date	2024-02-17
Publishing country	United States
Document type	Review ; Journal Article
ZDB-ID	1439041-3
ISSN	1643-3750 ; 1234-1010
ISSN (online)	1643-3750
ISSN	1234-1010
DOI	10.12659/MSM.943181
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Zs.A 4924: Show issues

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Article ; Online: Neurocomputational Substrates Underlying the Effect of Identifiability on Third-Party Punishment.

Feng, Chunliang / Tian, Xia / Luo, Yue-Jia

The Journal of neuroscience : the official journal of the Society for Neuroscience

2023 Volume 43, Issue 47, Page(s) 8018–8031

Abstract: The identifiable target effect refers to the preference for helping identified victims and punishing identifiable perpetrators compared with equivalent but unidentifiable counterparts. The identifiable target effect is often attributed to the heightened ... ...

Abstract	The identifiable target effect refers to the preference for helping identified victims and punishing identifiable perpetrators compared with equivalent but unidentifiable counterparts. The identifiable target effect is often attributed to the heightened moral emotions evoked by identified targets. However, the specific neurocognitive processes that mediate and/or modulate this effect remain largely unknown. Here, we combined a third-party punishment game with brain imaging and computational modeling to unravel the neurocomputational underpinnings of the identifiable transgressor effect. Human participants (males and females) acted as bystanders and punished identified or anonymous wrongdoers. Participants were more punitive toward identified wrongdoers than anonymous wrongdoers because they took a vicarious perspective of victims and adopted lower reference points of inequity (i.e., more stringent norms) in the identified context than in the unidentified context. Accordingly, there were larger activity of the ventral anterior insula, more distinct multivariate neural patterns in the dorsal anterior insula and dorsal anterior cingulate cortex, and lower strength between ventral anterior insula and dorsolateral PFC and between dorsal anterior insula and ventral striatum connectivity in response to identified transgressors than anonymous transgressors. These findings implicate the interplay of expectancy violations, emotions, and self-interest in the identifiability effect. Last, individual differences in the identifiability effect were associated with empathic concern/social dominance orientation, activity in the precuneus/cuneus and temporo-parietal junction, and intrinsic functional connectivity of the dorsolateral PFC. Together, our work is the first to uncover the neurocomputational processes mediating identifiable transgressor effect and to characterize psychophysiological profiles modulating the effect.
MeSH term(s)	Male ; Female ; Humans ; Punishment/psychology ; Brain/diagnostic imaging ; Brain/physiology ; Emotions/physiology ; Brain Mapping ; Empathy ; Magnetic Resonance Imaging
Language	English
Publishing date	2023-11-22
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	604637-x
ISSN	1529-2401 ; 0270-6474
ISSN (online)	1529-2401
ISSN	0270-6474
DOI	10.1523/JNEUROSCI.0460-23.2023
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Zs.A 1668: Show issues

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Article ; Online: Silencing circUSP48 suppresses osteosarcoma progression by regulating the miR-335/ smad nuclear interacting protein 1 pathway.

Luo, Yue / Yang, Bo / Yuan, Xiaopin / Zheng, Jian

Journal of clinical laboratory analysis

2023 Volume 37, Issue 2, Page(s) e24828

Abstract: Background: Circular RNAs (circRNAs) can have a critical function in the multi-processes of osteosarcoma (OS). Nevertheless, whether circUSP48 is involved in OS progression remains unclear.: Methods: In the current work, the expression of circUSP48, ... ...

Abstract	Background: Circular RNAs (circRNAs) can have a critical function in the multi-processes of osteosarcoma (OS). Nevertheless, whether circUSP48 is involved in OS progression remains unclear. Methods: In the current work, the expression of circUSP48, miR-335 and SNIP1 in OS cell lines and tissues were evaluated using qRT-PCR. Then, Sanger sequencing, RNase R treatment and FISH assay were performed for circUSP48 validation. Furthermore, the function and potential mechanisms of circUSP48 in OS were investigated by performing loss-of-function experiments. Results: Silencing circUSP48 could suppress proliferation, invasion as well as migration of OS cells in vitro, also inhibiting the growth of tumor in vivo. Importantly, circUSP48 promoted OS malignancy by sponging miR-335 to upregulate SNIP1. Conclusion: Overall, these findings suggested that circUSP48 acted as an oncogene in OS, which might become a new target for OS therapy.
MeSH term(s)	Humans ; MicroRNAs/metabolism ; Cell Proliferation ; Apoptosis ; Cell Movement ; Osteosarcoma/genetics ; Bone Neoplasms/genetics ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic
Chemical Substances	MicroRNAs ; MIRN335 microRNA, human
Language	English
Publishing date	2023-01-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	645095-7
ISSN	1098-2825 ; 0887-8013
ISSN (online)	1098-2825
ISSN	0887-8013
DOI	10.1002/jcla.24828
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Zs.A 2471: Show issues

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Article ; Online: Comparative effectiveness and safety of intravenous methylprednisolone and tacrolimus monotherapy in ocular myasthenia gravis with unsatisfactory prednisone responses: a retrospective study.

Zhang, Kai-Yue / Duan, Wei-Wei / Luo, Yue-Bei / Li, Yi / Hu, Jue / Yang, Huan

Orphanet journal of rare diseases

2024 Volume 19, Issue 1, Page(s) 19

Abstract: Background: Oral prednisone has been recognized as the first-line therapy for the treatment of ocular myasthenia gravis (OMG). However, its long-term use is complicated by numerous adverse effects and is ineffective for some OMG patients in reaching ... ...

Abstract	Background: Oral prednisone has been recognized as the first-line therapy for the treatment of ocular myasthenia gravis (OMG). However, its long-term use is complicated by numerous adverse effects and is ineffective for some OMG patients in reaching remission. This study aimed to evaluate the effectiveness and safety of intravenous methylprednisolone (IVMP) and tacrolimus monotherapy for OMG patients with unsatisfactory responses to conventional prednisone therapy. Methods: We retrospectively reviewed 57 OMG patients who had not achieved satisfactory improvement after prednisone therapy and thereby received IVMP or tacrolimus monotherapy for at least 6 months. Ocular symptoms were evaluated by the ocular-quantitative MG (QMG) score at each time point. A ≥ 2-point fall in ocular QMG score was defined as the cut-off point to indicate clinical improvement. Logistic regression analysis was performed to identify factors associated with the efficacy of IVMP at discharge. Adverse events were recorded. Results: Both IVMP and tacrolimus monotherapy demonstrated significant clinical efficacy, with no statistical differences observed at the study endpoint. The proportions of patients who reached the cut-off point for efficacy evaluation were higher in the IVMP group than in the tacrolimus group (1, 3, and 6 months: 51.7% (15/29) vs 12.0% (3/25), p = 0.002; 69.0% (20/29) vs 40.0% (10/25), p = 0.033; 69.0% (20/29) vs 46.4% (13/28), p = 0.085, respectively). Multivariate logistics analysis showed that high ocular QMG scores at baseline indicated favourable responses to IVMP treatment (OR = 1.781; 95% CI 1.066-2.975; p = 0.028). All the adverse events were transient and tolerable. Conclusion: Our findings suggest that both IVMP and tacrolimus monotherapy hold promise as viable treatment options for OMG patients with unsatisfactory responses to oral prednisone. The study supports the safety and effectiveness of both therapies, with IVMP exhibiting faster improvement and favourable efficacy in patients with high ocular QMG scores.
MeSH term(s)	Humans ; Prednisone/therapeutic use ; Retrospective Studies ; Methylprednisolone/therapeutic use ; Tacrolimus/therapeutic use ; Myasthenia Gravis/drug therapy ; Treatment Outcome
Chemical Substances	Prednisone (VB0R961HZT) ; Methylprednisolone (X4W7ZR7023) ; Tacrolimus (WM0HAQ4WNM)
Language	English
Publishing date	2024-01-19
Publishing country	England
Document type	Journal Article
ZDB-ID	2225857-7
ISSN	1750-1172 ; 1750-1172
ISSN (online)	1750-1172
ISSN	1750-1172
DOI	10.1186/s13023-024-03025-z
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Dynamic Organization of Large-scale Functional Brain Networks Supports Interactions Between Emotion and Executive Control.

Geng, Haiyang / Xu, Pengfei / Aleman, Andre / Qin, Shaozheng / Luo, Yue-Jia

Neuroscience bulletin

2024

Abstract: Emotion and executive control are often conceptualized as two distinct modes of human brain functioning. Little, however, is known about how the dynamic organization of large-scale functional brain networks that support flexible emotion processing and ... ...

Abstract	Emotion and executive control are often conceptualized as two distinct modes of human brain functioning. Little, however, is known about how the dynamic organization of large-scale functional brain networks that support flexible emotion processing and executive control, especially their interactions. The amygdala and prefrontal systems have long been thought to play crucial roles in these processes. Recent advances in human neuroimaging studies have begun to delineate functional organization principles among the large-scale brain networks underlying emotion, executive control, and their interactions. Here, we propose a dynamic brain network model to account for interactive competition between emotion and executive control by reviewing recent resting-state and task-related neuroimaging studies using network-based approaches. In this model, dynamic interactions among the executive control network, the salience network, the default mode network, and sensorimotor networks enable dynamic processes of emotion and support flexible executive control of multiple processes; neural oscillations across multiple frequency bands and the locus coeruleus-norepinephrine pathway serve as communicational mechanisms underlying dynamic synergy among large-scale functional brain networks. This model has important implications for understanding how the dynamic organization of complex brain systems and networks empowers flexible cognitive and affective functions.
Language	English
Publishing date	2024-01-23
Publishing country	Singapore
Document type	Journal Article ; Review
ZDB-ID	2419741-5
ISSN	1995-8218 ; 1673-7067
ISSN (online)	1995-8218
ISSN	1673-7067
DOI	10.1007/s12264-023-01168-w
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Zs.A 6734: Show issues

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Article ; Online: Hypoglycemic effects and associated mechanisms of resveratrol and related stilbenes in diet.

Peng, Jie / Lu, Chenyang / Luo, Yue / Su, Xiurong / Li, Shiming / Ho, Chi-Tang

Food & function

2024 Volume 15, Issue 5, Page(s) 2381–2405

Abstract: Hyperglycemia has become a global health problem due to changes in diet and lifestyle. Most importantly, persistent hyperglycemia can eventually develop into type II diabetes. While the usage of current drugs is limited by their side effects, stilbenes ... ...

Abstract	Hyperglycemia has become a global health problem due to changes in diet and lifestyle. Most importantly, persistent hyperglycemia can eventually develop into type II diabetes. While the usage of current drugs is limited by their side effects, stilbenes derived from fruits and herbal/dietary plants are considered as important phytochemicals with potential hypoglycemic properties. Herein, the most common stilbenoids in consumed foods,
MeSH term(s)	Humans ; Hypoglycemic Agents/pharmacology ; Resveratrol/pharmacology ; Diabetes Mellitus, Type 2 ; Diet ; Hyperglycemia ; Stilbenes/pharmacology ; Stilbenes/chemistry ; Insulins
Chemical Substances	Hypoglycemic Agents ; Resveratrol (Q369O8926L) ; Stilbenes ; Insulins
Language	English
Publishing date	2024-03-04
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2612033-1
ISSN	2042-650X ; 2042-6496
ISSN (online)	2042-650X
ISSN	2042-6496
DOI	10.1039/d3fo04761j
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Z 7872: Show issues

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Article ; Online: Unveiling cell subpopulations in T1D mouse islets using single-cell RNA sequencing.

Yang, Huan / Luo, Junming / Liu, Xuyang / Luo, Yue / Lai, Xiaoyang / Zou, Fang

American journal of physiology. Endocrinology and metabolism

2024

Abstract: Type 1 diabetes (T1D) is an autoimmune disease characterized by the destruction of β cells by immune cells. The interactions among cells within the islets may be closely linked to the pathogenesis of T1D. In this study, we utilized single-cell RNA ... ...

Abstract	Type 1 diabetes (T1D) is an autoimmune disease characterized by the destruction of β cells by immune cells. The interactions among cells within the islets may be closely linked to the pathogenesis of T1D. In this study, we utilized single-cell RNA sequencing (scRNA-seq) to analyze the cellular heterogeneity within the islets of a T1D mouse model. We established a T1D mouse model induced by streptozotocin and identified cell subpopulations using scRNA-seq technology. Our results revealed 11 major cell types in the pancreatic islets of T1D mice, with heterogeneity observed in the alpha and beta cell subgroups, which may play a crucial role in the progression of T1D. Flow cytometry further confirmed a mature alpha and beta cell reduction in T1D mice. Overall, our scRNA-seq analysis provided insights into the cellular heterogeneity of T1D islet tissue and highlighted the potential importance of alpha and beta cells in developing T1D. NEW & NOTEWORTHY Created a comprehensive single-cell atlas of pancreatic islets in a T1D mouse model using scRNA-seq. Identified 11 major cell types in the islets, highlighting the role of alpha and beta cells in T1D. Revealed significant reduction in maturity alpha and beta cells in T1D mice through flow cytometry. Demonstrated the heterogeneity of alpha and beta cells, potentially crucial for T1D progression. Provided new insights for understanding and treating T1D by studying cell subtype changes and functions.
Language	English
Publishing date	2024-03-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	603841-4
ISSN	1522-1555 ; 0193-1849
ISSN (online)	1522-1555
ISSN	0193-1849
DOI	10.1152/ajpendo.00323.2023
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Uc I Zs.89: Show issues

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Article: A Narrative Review of Diabetic Macroangiopathy: From Molecular Mechanism to Therapeutic Approaches.

Yin, Jiacheng / Fu, Xiaoxu / Luo, Yue / Leng, Yuling / Ao, Lianjun / Xie, Chunguang

Diabetes therapy : research, treatment and education of diabetes and related disorders

2024 Volume 15, Issue 3, Page(s) 585–609

Abstract: Diabetic macroangiopathy, a prevalent and severe complication of diabetes mellitus, significantly contributes to the increased morbidity and mortality rates among affected individuals. This complex disorder involves multifaceted molecular mechanisms that ...

Abstract	Diabetic macroangiopathy, a prevalent and severe complication of diabetes mellitus, significantly contributes to the increased morbidity and mortality rates among affected individuals. This complex disorder involves multifaceted molecular mechanisms that lead to the dysfunction and damage of large blood vessels, including atherosclerosis (AS) and peripheral arterial disease. Understanding the intricate pathways underlying the development and progression of diabetic macroangiopathy is crucial for the development of effective therapeutic interventions. This review aims to shed light on the molecular mechanism implicated in the pathogenesis of diabetic macroangiopathy. We delve into the intricate interplay of chronic inflammation, oxidative stress, endothelial dysfunction, and dysregulated angiogenesis, all of which contribute to the vascular complications observed in this disorder. By exploring the molecular mechanism involved in the disease we provide insight into potential therapeutic targets and strategies. Moreover, we discuss the current therapeutic approaches used for treating diabetic macroangiopathy, including glycemic control, lipid-lowering agents, and vascular interventions.
Language	English
Publishing date	2024-02-02
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2566702-6
ISSN	1869-6961 ; 1869-6953
ISSN (online)	1869-6961
ISSN	1869-6953
DOI	10.1007/s13300-024-01532-7
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Article ; Online: Reading anxiety modulates the functional connectivity of the reading-related network during adult reading.

Li, Hehui / Yuan, Binke / Luo, Yue-Jia / Liu, Jie

Brain and language

2023 Volume 242, Page(s) 105278

Abstract: Researchers have studied cognitive and linguistic skills in predicting reading abilities, but the impact of affective factors such as anxiety on reading at the neurobiological level is not well understood. Here, we used functional magnetic resonance ... ...

Abstract	Researchers have studied cognitive and linguistic skills in predicting reading abilities, but the impact of affective factors such as anxiety on reading at the neurobiological level is not well understood. Here, we used functional magnetic resonance imaging to investigate the neural correlates of reading anxiety in adult readers performing a semantic judgment task. The results showed that reading anxiety was significantly correlated with response time but not with accuracy. Neurobiologically, functional connectivity strength rather than activation level of semantic-related areas significantly predicted reading anxiety. Activation of regions (i.e., the right putamen and right precentral gyrus) external to the semantic-related areas positively correlated with reading anxiety levels. These findings suggest that reading anxiety influences adult reading by modulating functional connections of semantic-related areas and brain activation of semantic-unrelated areas. This study provides insights into the neural mechanisms underlying reading anxiety experienced by adult readers.
MeSH term(s)	Humans ; Adult ; Reading ; Brain Mapping/methods ; Brain/diagnostic imaging ; Brain/physiology ; Cognition/physiology ; Anxiety/diagnostic imaging ; Magnetic Resonance Imaging/methods
Language	English
Publishing date	2023-05-18
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	7448-2
ISSN	1090-2155 ; 0093-934X
ISSN (online)	1090-2155
ISSN	0093-934X
DOI	10.1016/j.bandl.2023.105278
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