LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 10

Search options

  1. Article: Atypical Tongue Abscesses Mimicking Submucosal Malignancies: A Review of the Literature Focusing on Diagnostic Challenges.

    Rampi, Andrea / Tettamanti, Alberto / Bertotto, Ilaria / Comini, Lara Valentina / Howardson, Bright Oworae / Luparello, Paolo / Di Santo, Davide / Bondi, Stefano

    Cancers

    2023  Volume 15, Issue 24

    Abstract: Tongue abscesses are rare conditions that usually follow mucosal disruption due to mechanical trauma or foreign body impaction. They typically manifest abruptly as a rapidly growing, hard mass or swelling in the context of tongue muscles; the patient ... ...

    Abstract Tongue abscesses are rare conditions that usually follow mucosal disruption due to mechanical trauma or foreign body impaction. They typically manifest abruptly as a rapidly growing, hard mass or swelling in the context of tongue muscles; the patient frequently complains of pain, difficulties in swallowing or speaking, and fever. Nonetheless, the features of its presentation, together with accurate clinical evaluation, blood tests, and appropriate imaging tests, are usually sufficient to easily discern a tongue abscess from a malignancy. However, in rare cases, they may occur with slowly progressing and subtle symptoms, nuanced objective and laboratory findings, and inconclusive radiological evidence, leading to difficult differential diagnosis with submucosal malignancy. Herein, we review the literature, available on Pubmed, Embase, and Scopus, on publications reporting tongue abscesses, with atypical presentation suggesting an oral tumor. Our review confirms that tongue abscesses may manifest as a slowly growing and moderately painful swelling without purulent discharge and minimal mucosal inflammation; in this case, they may constitute an actual diagnostic challenge with potentially severe impact on correct management. Atypical tongue abscesses must therefore be considered in the differential diagnosis of tongue malignancy with submucosal extension, even when other diagnostic elements suggest a neoplasia; in this case, a deep biopsy under general anesthesia is essential for differential diagnosis, and simultaneous drainage of the necrotic and abscessual material may resolve the condition.
    Language English
    Publishing date 2023-12-17
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers15245871
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Dynamic Study of Oesophageal Function during Phonation: Simple but Effective.

    Santoro, Giovanni Paolo / Maniaci, Antonino / Luparello, Paolo / Ferlito, Salvatore / Cocuzza, Salvatore

    ORL; journal for oto-rhino-laryngology and its related specialties

    2021  Volume 83, Issue 5, Page(s) 304–309

    Abstract: Secondary aphonia significantly affects the quality of life of the laryngectomy patient despite the excellent success of the operation. Vocal rehabilitation often does not achieve the desired results, given the innumerable prognostic variables. Tracheo- ... ...

    Abstract Secondary aphonia significantly affects the quality of life of the laryngectomy patient despite the excellent success of the operation. Vocal rehabilitation often does not achieve the desired results, given the innumerable prognostic variables. Tracheo-oesophageal speech is considered the standard gold method of voice restoration, but a possible spasm of pharyngo-oesophageal segment is the prominent cause of rehabilitation failure. However, the phenomenon is difficult to identify and underestimated, and diagnostic methods are inquisitive or expensive. To propose a phonatory and swallowing evaluation essay of pharynx-oesophageal segment disorders, we conducted a retrospective study from 2012 to 2017 by selecting 6 patients who underwent total laryngectomy and voice prosthesis implantation that suffered from aphonia after surgery. All patients underwent dynamic phonation videofluoroscopy and plexus bath control test with lidocaine hydrochloride. All patients were then referred for treatment with neurotoxin blocker. In all cases, the analysed patients presented an air-trapping phenomenon with the formation of a spasmodic block upstream of an interrupted aerial column. The control test with lidocaine hydrochloride resulted in a transient improvement in speech performance. The neurotoxin block therapy subsequently performed ultimately led to an improvement in the patient's rehabilitation process with a recovery of the phonatory performance. We describe the new use of a barium bolus as a diagnostic tool for identifying neopharynx disorders. Appropriately selected patients with pharynx-oesophageal segment disorders could benefit from a neurotoxin-blocking treatment to improve oesophageal speech.
    MeSH term(s) Humans ; Laryngectomy ; Larynx, Artificial ; Phonation ; Quality of Life ; Retrospective Studies ; Speech, Esophageal
    Language English
    Publishing date 2021-05-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 121482-2
    ISSN 1423-0275 ; 0301-1569
    ISSN (online) 1423-0275
    ISSN 0301-1569
    DOI 10.1159/000513889
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Rhino-oropharingeal osteoradionecrotic soft-tissue and bony defect reconstruction with submental artery island flap: a case report.

    Lucattelli, Elena / Menichini, Giulio / Luparello, Paolo / Boschi, Andrea / Maggiore, Giandomenico / Innocenti, Marco / Innocenti, Alessandro

    British journal of neurosurgery

    2021  Volume 37, Issue 6, Page(s) 1850–1852

    Abstract: Background: The submental artery island flap is widely used in head and neck reconstruction, since it is easy and quick to harvest, and it can be successfully used for the coverage of perioral, intraoral and facial defects. We used this technique for ... ...

    Abstract Background: The submental artery island flap is widely used in head and neck reconstruction, since it is easy and quick to harvest, and it can be successfully used for the coverage of perioral, intraoral and facial defects. We used this technique for the reconstruction of a complex soft-tissue and bony defect of rhino-oropharinx.
    Case report: Osteoradionecrosis of rhino-oropharingeal posterior wall with C2 necrotic body exposure occurred in a 77-year-old woman. After the failure of reconstruction with a Hadad-Bassagasteguy flap, a submental island flap with cervical spine stabilization was planned to be performed in a one-stage operation. The anterior arc of C1 and odontoid process of C2 were removed and, according to the defect size, a submental island flap was designed in an elliptical fashion. The flap was rotated 180° and tunnelized under the left parapharingeal-prevertebral space, then it was positioned in the rhino-oropharinx and fixed with reabsorbable sutures. The donor site was closed primarily. No peri- or post-operative complications occurred, neither in the recipient nor in the donor-site. At the latest follow-up, 15 months postoperatively, the patient was able to speak without any impairment and started swallowing rehabilitation with good results and an aesthetically satisfactory outcome.
    Conclusion: The submental island flap may be a reliable and versatile flap for reconstruction of head and neck defects, even though in the rhino-oropharingeal posterior wall.
    MeSH term(s) Female ; Humans ; Aged ; Plastic Surgery Procedures ; Osteoradionecrosis/surgery ; Surgical Flaps ; Neck/surgery ; Arteries/surgery ; Treatment Outcome
    Language English
    Publishing date 2021-06-29
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 639029-8
    ISSN 1360-046X ; 0268-8697
    ISSN (online) 1360-046X
    ISSN 0268-8697
    DOI 10.1080/02688697.2021.1941758
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Current evidence on diagnosis and treatment of parotid gland lymphomas: a systematic review.

    Di Santo, Davide / Bramati, Chiara / Festa, Bianca Maria / Pace, Gian Marco / Comini, Lara Valentina / Luparello, Paolo / Cascardi, Eliano / Galizia, Danilo / Galli, Andrea / De Virgilio, Armando / Giordano, Leone / Bondi, Stefano

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

    2023  Volume 280, Issue 12, Page(s) 5219–5227

    Abstract: Background and purpose: Parotid gland lymphoma (PGL) is a rare and challenging diagnosis. Different lymphomas can develop in the parotid gland, with the most common being the mucosa-associated lymphoid tissue (MALT) lymphoma, which originates directly ... ...

    Abstract Background and purpose: Parotid gland lymphoma (PGL) is a rare and challenging diagnosis. Different lymphomas can develop in the parotid gland, with the most common being the mucosa-associated lymphoid tissue (MALT) lymphoma, which originates directly from the glandular parenchyma. Other histologic subtypes arise from both intraglandular and extraglandular parotid lymph nodes. A consensus on diagnosis and treatment of PGL is still lacking, and published data is scarce and heterogeneous.
    Methods: We performed a systematic review of the literature, including studies published after 2001, when the WHO classification of lymphoid tumours was introduced.
    Results: Twenty retrospective studies were included in the analyses, eight of which focused exclusively on MALT lymphomas. Final analysis included 612 cases of PGL, with a 1.68:1 F/M ratio. MALT lymphoma was the most common histology, followed by follicular and diffuse large B-cell lymphoma. Most cases were low stages (IE/IIE acc. Ann Arbour, 76.5%) and only 10% of patients presented with symptoms, most commonly pain (4.8%) and B symptoms (2.2%). A high prevalence of associated autoimmune diseases was found, particularly Sjögren's syndrome, that affected up to 70% of patients with MALT lymphoma. In most cases diagnosis was achieved through parotidectomy (57.5%), or open biopsy (31.2%). Treatment strategies were either surgical, non-surgical or a combination of modalities. Surgery as a single-modality treatment was reported in about 20% of patients, supposing it might be a valuable option for selected patients.
    Conclusions: Our review showed that the diagnosis and treatment of PGLs is far from being standardized and needs further, more homogeneous reports to reach consensus.
    MeSH term(s) Humans ; Parotid Gland/pathology ; Lymphoma, B-Cell, Marginal Zone/diagnosis ; Lymphoma, B-Cell, Marginal Zone/therapy ; Lymphoma, B-Cell, Marginal Zone/complications ; Retrospective Studies ; Salivary Glands/pathology ; Sjogren's Syndrome/complications ; Sjogren's Syndrome/diagnosis ; Parotid Neoplasms/diagnosis ; Parotid Neoplasms/surgery
    Language English
    Publishing date 2023-08-28
    Publishing country Germany
    Document type Systematic Review ; Journal Article ; Review
    ZDB-ID 1017359-6
    ISSN 1434-4726 ; 0937-4477
    ISSN (online) 1434-4726
    ISSN 0937-4477
    DOI 10.1007/s00405-023-08206-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: Conservative treatment for advanced T3-T4 laryngeal cancer: meta-analysis of key oncological outcomes.

    Mannelli, Giuditta / Lazio, Maria Silvia / Luparello, Paolo / Gallo, Oreste

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

    2018  Volume 275, Issue 1, Page(s) 27–38

    Abstract: Goal: Controversies exist regarding the treatment of advanced laryngeal carcinomas. The purpose of this systematic review was to evaluate the oncologic outcomes of both transoral laser and open partial laryngectomies for advanced (T3-T4) squamous cell ... ...

    Abstract Goal: Controversies exist regarding the treatment of advanced laryngeal carcinomas. The purpose of this systematic review was to evaluate the oncologic outcomes of both transoral laser and open partial laryngectomies for advanced (T3-T4) squamous cell laryngeal cancers management.
    Introduction: A systematic review of literature was led searching for articles mentioning the following terms: advanced (T3-T4) laryngeal cancer AND laser; AND open partial laryngectomy; AND transoral laser microsurgery; AND cordectomy; AND conservative surgery; AND tracheohyoidopexy or tracheohyoidoepiglottopexy; AND supratracheal partial laryngectomy; AND supracricoid partial laryngectomy; AND cricohyoidopexy or cricohyoidoepiglottopexy. Then a quantitative analysis was carried on papers published after 1980.
    Discussion: The search identified 110 publications, and a total of 21 articles satisfied inclusion criteria and were selected for quantitative synthesis. 10 out of 21 studies had a good quality score, 10 were fair and only one rated a poor score. The pooled disease-free survival (DFS) was 79% (95% CI 74-85), and pooled overall survival (OS) was 71% (95% CI 64-78) at 5 years from all 1921 patients included in the study, with significant heterogeneity (I
    Conclusion: The two surgical techniques are both valid conservative surgical options for advanced laryngeal cancer treatment.
    MeSH term(s) Conservative Treatment/methods ; Humans ; Laryngeal Neoplasms/mortality ; Laryngeal Neoplasms/pathology ; Laryngeal Neoplasms/surgery ; Laryngectomy/methods ; Laser Therapy/methods ; Neoplasm Staging ; Survival Analysis ; Treatment Outcome
    Language English
    Publishing date 2018-01
    Publishing country Germany
    Document type Journal Article ; Meta-Analysis ; Review
    ZDB-ID 1017359-6
    ISSN 1434-4726 ; 0937-4477
    ISSN (online) 1434-4726
    ISSN 0937-4477
    DOI 10.1007/s00405-017-4799-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Myotomy of sternocleidomastoid muscle as a secondary procedure in laryngectomized patients.

    Santoro, Giovanni Paolo / Luparello, Paolo / Lazio, Maria Silvia / Comini, Lara Valentina / Martelli, Federica / Cannavicci, Angelo

    Head & neck

    2019  Volume 41, Issue 10, Page(s) 3743–3746

    Abstract: Background: The application of specific devices to seal the tracheal stoma in laryngectomized patients is critical for optimal pulmonary and phonatory rehabilitation. Indeed, an excessive stomal depth is one of the main causes of rehabilitation failure. ...

    Abstract Background: The application of specific devices to seal the tracheal stoma in laryngectomized patients is critical for optimal pulmonary and phonatory rehabilitation. Indeed, an excessive stomal depth is one of the main causes of rehabilitation failure. In this context, division of the sternal heads of the sternocleidomastoid muscle (SCM) is a common technique, usually performed during the laryngectomy.
    Methods: We perform a myotomy of the sternal head of the SCM in deep and narrow tracheal stoma as a secondary procedure under local anesthesia, and here we describe the surgical steps of this procedure.
    Results: The medium depth of the stoma is reduced, and no procedure-specific complications have been observed. Postoperative morphological features show a flattening of the peristomal area, and all patients have begun regular use of appropriate patches and filters.
    Conclusions: Secondary section of SCM is a safe, simple, and effective procedure in total laryngectomies with deep and narrow stoma.
    MeSH term(s) Adult ; Female ; Follow-Up Studies ; Humans ; Laryngeal Neoplasms/pathology ; Laryngeal Neoplasms/surgery ; Laryngectomy/adverse effects ; Laryngectomy/methods ; Male ; Middle Aged ; Myotomy/methods ; Neck Muscles/surgery ; Patient Safety ; Quality of Life ; Reoperation/methods ; Surgical Stomas ; Treatment Outcome
    Language English
    Publishing date 2019-07-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 645165-2
    ISSN 1097-0347 ; 0148-6403 ; 1043-3074
    ISSN (online) 1097-0347
    ISSN 0148-6403 ; 1043-3074
    DOI 10.1002/hed.25852
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Outcomes of endoscopic sinus surgery in adult lung transplant patients with cystic fibrosis.

    Luparello, Paolo / Lazio, Maria S / Voltolini, Luca / Borchi, Beatrice / Taccetti, Giovanni / Maggiore, Giandomenico

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

    2019  Volume 276, Issue 5, Page(s) 1341–1347

    Abstract: Purpose: Cystic Fibrosis (CF) is the most common autosomal recessive disease in Caucasian population. Due to its pathological mechanism, chronic rhino sinusitis (CRS) associated or not with nasal polyposis usually occurs in adults and affects close to ... ...

    Abstract Purpose: Cystic Fibrosis (CF) is the most common autosomal recessive disease in Caucasian population. Due to its pathological mechanism, chronic rhino sinusitis (CRS) associated or not with nasal polyposis usually occurs in adults and affects close to one-half of all CF patients. The goal of our work was to evaluate the impact of Endoscopic Sinus Surgery (ESS) in the quality of life (QoL) of the CF patients and demonstrate an improvement of the functional outcomes in the patients underwent the surgical procedure rather than in the not treated ones, particulary in lung transplant patients.
    Methods: We studied 54 adult patients affected by CF. Lund-Kennedy, Lund-Mackay scores, and SNOT-22 were analysed. 14 had lung transplant and 9 had both lung tranplant and ESS procedures.
    Results: 22 (40.7%) out of 54 CF patients underwent ESS. This group presented more likely complaints consistent with CRS. Lund-Kennedy and Lund-Mackay scores appeared higher in the ESS group: 10 (range of 6-12) and 15 (range of 12-20), respectively. SNOT-22 showed median values for non-ESS and ESS group of 20 (range of 3-68) and 40 (range of 10-73), respectively.
    Conclusions: ESS represents the best option to improve clinical QoL of CF patients who do not response to conventional medical therapy, with a stabilization of respiratory function after transplantation.
    MeSH term(s) Adult ; Chronic Disease ; Cystic Fibrosis/complications ; Cystic Fibrosis/psychology ; Cystic Fibrosis/surgery ; Endoscopy/methods ; Female ; Humans ; Lung Transplantation/adverse effects ; Lung Transplantation/methods ; Male ; Middle Aged ; Nasal Polyps/complications ; Nasal Polyps/surgery ; Paranasal Sinuses/pathology ; Paranasal Sinuses/radiation effects ; Paranasal Sinuses/surgery ; Quality of Life ; Rhinitis/complications ; Rhinitis/surgery ; Sinusitis/complications ; Sinusitis/surgery ; Treatment Outcome ; Young Adult
    Language English
    Publishing date 2019-01-28
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1017359-6
    ISSN 1434-4726 ; 0937-4477
    ISSN (online) 1434-4726
    ISSN 0937-4477
    DOI 10.1007/s00405-019-05308-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Quality of Life and Impact of Endoscopic Sinus Surgery in Adult Patients With Cystic Fibrosis.

    Lazio, Maria S / Luparello, Paolo / Mannelli, Giuditta / Santoro, Giovanni P / Bresci, Silvia / Braggion, Cesare / Gallo, Oreste / Maggiore, Giandomenico

    American journal of rhinology & allergy

    2019  Volume 33, Issue 4, Page(s) 413–419

    MeSH term(s) Adult ; Chronic Disease ; Cystic Fibrosis/psychology ; Cystic Fibrosis/surgery ; Female ; Humans ; Male ; Natural Orifice Endoscopic Surgery ; Quality of Life ; Rhinitis/psychology ; Rhinitis/surgery ; Sinusitis/psychology ; Sinusitis/surgery ; Surveys and Questionnaires ; Treatment Outcome
    Language English
    Publishing date 2019-04-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2482804-X
    ISSN 1945-8932 ; 1945-8924
    ISSN (online) 1945-8932
    ISSN 1945-8924
    DOI 10.1177/1945892419839260
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: A new, easy, and swift technique for minor salivary gland biopsy in Sjogren's syndrome.

    Comini, Lara Valentina / Lazio, Maria Silvia / Taverna, Cecilia / Luparello, Paolo / Maggiore, Giandomenico / Martelli, Federica / Novelli, Luca / Santoro, Giovanni Paolo

    The Laryngoscope

    2019  Volume 130, Issue 4, Page(s) 873–875

    MeSH term(s) Biopsy/methods ; Humans ; Lip ; Needles ; Salivary Glands, Minor/pathology ; Sjogren's Syndrome/pathology
    Language English
    Publishing date 2019-06-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80180-x
    ISSN 1531-4995 ; 0023-852X
    ISSN (online) 1531-4995
    ISSN 0023-852X
    DOI 10.1002/lary.28094
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: The surgical treatment of cerebrospinal fistula: Qualitative and quantitative analysis of indications and results.

    Iavarone, Alessandra / Luparello, Paolo / Lazio, Maria Silvia / Comini, Lara Valentina / Martelli, Federica / De Luca, Oliviero / Santoro, Giovanni Paolo / Santoro, Roberto / Alderotti, Giammarco / Mannelli, Giuditta

    Head & neck

    2019  Volume 42, Issue 2, Page(s) 344–356

    Abstract: Cerebrospinal fistula might occur in different ways. CSF closure techniques have undergone significant evolution that has led to the consolidation of the transnasal endoscopic approach. Despite the existence of multiple publications, meaningful ... ...

    Abstract Cerebrospinal fistula might occur in different ways. CSF closure techniques have undergone significant evolution that has led to the consolidation of the transnasal endoscopic approach. Despite the existence of multiple publications, meaningful information is still lacking in clinical practice and the literature about the ideal method, material, and timing for repair of CSF. The purpose of this review was to summarize the success rate of endoscopic CSF leak repair as well as whether specific techniques or materials influence the primary success rate through a review of the latest advancements in endoscopic CSF management published in the past 10 years. The principles of multilayer reconstructions and the routine use of vascularized flaps in expanded endonasal surgery have reduced postoperative CSF leaks' failure rates between 5% and 10% (4% in this meta-analysis). Effective endoscopic anterior skull base (ASB) closure may be achieved by multiple reconstructive techniques, which should be tailored case by case according to the patient and defect conditions.
    MeSH term(s) Cerebrospinal Fluid Leak/etiology ; Cerebrospinal Fluid Leak/surgery ; Endoscopy ; Fistula ; Humans ; Reconstructive Surgical Procedures ; Retrospective Studies ; Skull Base/surgery ; Surgical Flaps
    Language English
    Publishing date 2019-11-04
    Publishing country United States
    Document type Journal Article ; Meta-Analysis ; Review
    ZDB-ID 645165-2
    ISSN 1097-0347 ; 0148-6403 ; 1043-3074
    ISSN (online) 1097-0347
    ISSN 0148-6403 ; 1043-3074
    DOI 10.1002/hed.25981
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top