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Article ; Online: Hydroxychloroquine + azithromycin treatment in elderly patients.

Gautret, Philippe / Ly, Tran Duc Anh / Raoult, Didier

International journal of antimicrobial agents

2021 Volume 57, Issue 4, Page(s) 106313

MeSH term(s)	Aged ; Azithromycin/adverse effects ; Azithromycin/therapeutic use ; COVID-19/drug therapy ; COVID-19/prevention & control ; Drug Therapy, Combination ; Frail Elderly/statistics & numerical data ; Humans ; Hydroxychloroquine/adverse effects ; Hydroxychloroquine/therapeutic use ; Nursing Homes ; SARS-CoV-2/drug effects
Chemical Substances	Hydroxychloroquine (4QWG6N8QKH) ; Azithromycin (83905-01-5)
Language	English
Publishing date	2021-03-11
Publishing country	Netherlands
Document type	Letter
ZDB-ID	1093977-5
ISSN	1872-7913 ; 0924-8579
ISSN (online)	1872-7913
ISSN	0924-8579
DOI	10.1016/j.ijantimicag.2021.106313
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Zs.A 3368: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Pneumococcal infections and homelessness.

Ly, Tran Duc Anh / Perieres, Lauren / Hoang, VAN Thuan / Dao, Thi Loi / Gautret, Philippe

Journal of preventive medicine and hygiene

2022 Volume 62, Issue 4, Page(s) E950–E957

Abstract: Objective: To assess the prevalence of pneumococcal nasopharyngeal carriage, the role of potential risk factors, and the pneumococcal vaccination coverage among sheltered homeless people in Marseille, France.: Methods: During the winters 2015-2018, ... ...

Abstract	Objective: To assess the prevalence of pneumococcal nasopharyngeal carriage, the role of potential risk factors, and the pneumococcal vaccination coverage among sheltered homeless people in Marseille, France. Methods: During the winters 2015-2018, we enrolled 571 sheltered homeless males and 54 non-homeless controls. Streptococcus pneumoniae was directly searched from nasal/pharyngeal samples using real-time polymerase chain reaction. Results: The homeless people were mostly migrants from African countries, with a mean age of 43 years. Pneumococcal vaccination coverage was low (3.1%). The overall pneumococcal carriage rate was 13.0% and was significantly higher in homeless people (15.3% in 2018) than in controls (3.7%), with p = 0.033. Among homeless people, being aged ≥ 65 years (1.97, 95% CI; 1.01-3.87), living in a specific shelter (OR = 1.80, 95% CI: 1.06-3.05), and having respiratory signs and symptoms at the time of enrolment (OR = 2.55, 95% CI: 1.54-4.21) were independently associated with pneumococcal carriage. Conclusion: Pneumococcal nasopharyngeal carriage, which is a precursor for pneumococcal disease in at-risk individuals, is frequent among French homeless people. Studies conducted in other countries have also reported outbreaks of pneumococcal infections in homeless people. Pneumococcal vaccination should be systematically considered for sheltered homeless people in France, as is being done in Canada since 2008.
MeSH term(s)	Adult ; Carrier State/epidemiology ; Homeless Persons ; Humans ; Infant ; Male ; Nasopharynx ; Pneumococcal Infections/epidemiology ; Pneumococcal Infections/prevention & control ; Pneumococcal Vaccines ; Prevalence ; Streptococcus pneumoniae
Chemical Substances	Pneumococcal Vaccines
Language	English
Publishing date	2022-01-31
Publishing country	Italy
Document type	Journal Article
ZDB-ID	1102926-2
ISSN	2421-4248 ; 1121-2233
ISSN (online)	2421-4248
ISSN	1121-2233
DOI	10.15167/2421-4248/jpmh2021.62.4.1805
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Zs.B 990: Show issues

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Article ; Online: Epidemiological Investigations of Infectious Diseases among Mobile Populations at the University Hospital Institute Mediterranean Infection in Marseille, France.

Dao, Thi Loi / Hoang, Van Thuan / Ly, Tran Duc Anh / Goumballa, Ndiaw / Gautret, Philippe

Journal of epidemiology and global health

2021 Volume 11, Issue 3, Page(s) 271–282

Abstract: We review the most recent work conducted by our group on the circulation of infectious agents in mobile populations, including pilgrims participating in the Hajj (Mecca, Saudi Arabia) and the Grand Magal of Touba (Senegal) pilgrimages, homeless people, ... ...

Abstract	We review the most recent work conducted by our group on the circulation of infectious agents in mobile populations, including pilgrims participating in the Hajj (Mecca, Saudi Arabia) and the Grand Magal of Touba (Senegal) pilgrimages, homeless people, and medical students participating in an elective abroad. Using a similar epidemiological study design with standardized questionnaires and molecular assays allows comparison of different populations of travelers. The main infectious pathogens and antibiotic resistance genes linked to travel were identified in certain specific populations of travelers, as well as in a group of homeless migrant people in Marseille. The role of several risk factors has also been demonstrated, allowing identifying individuals at increased risk of disease or pathogen carriage on which to base targeted preventive measures. Such results, together with those obtained through international surveillance networks allow better description of the epidemiology of travel-associated infectious diseases.
MeSH term(s)	Communicable Diseases/epidemiology ; Hospitals, University ; Humans ; Islam ; Saudi Arabia ; Travel ; Travel-Related Illness
Language	English
Publishing date	2021-06-05
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2645324-1
ISSN	2210-6014 ; 2210-6014
ISSN (online)	2210-6014
ISSN	2210-6014
DOI	10.2991/jegh.k.210526.001
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Article ; Online: Annual variations of Haemophilus influenzae carriage among Hajj pilgrims.

Hoang, Van-Thuan / Dao, Thi-Loi / Ly, Tran Duc Anh / Pommier de Santi, Vincent / Gautret, Philippe

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology

2021 Volume 40, Issue 8, Page(s) 1787–1788

MeSH term(s)	Aged ; Carrier State ; Female ; Haemophilus Infections/epidemiology ; Haemophilus Infections/microbiology ; Haemophilus influenzae/isolation & purification ; Humans ; Islam ; Male ; Middle Aged ; Saudi Arabia/epidemiology ; Seasons ; Travel
Language	English
Publishing date	2021-05-28
Publishing country	Germany
Document type	Letter
ZDB-ID	603155-9
ISSN	1435-4373 ; 0934-9723 ; 0722-2211
ISSN (online)	1435-4373
ISSN	0934-9723 ; 0722-2211
DOI	10.1007/s10096-021-04276-5
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Article ; Online: Vaccine-preventable diseases other than tuberculosis, and homelessness: A scoping review of the published literature, 1980 to 2020.

Ly, Tran Duc Anh / Castaneda, Sergei / Hoang, Van Thuan / Dao, Thi Loi / Gautret, Philippe

Vaccine

2021 Volume 39, Issue 8, Page(s) 1205–1224

Abstract: Background: Homelessness may result in the breakdown of regular health services, including routine vaccination programmes. A scoping review was conducted to describe vaccine-preventable diseases (VPD) other than tuberculosis in people experiencing ... ...

Abstract	Background: Homelessness may result in the breakdown of regular health services, including routine vaccination programmes. A scoping review was conducted to describe vaccine-preventable diseases (VPD) other than tuberculosis in people experiencing homelessness (PEH). Methods: We followed the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR). We searched peer-reviewed literature published in English, French, Spanish or Portuguese reporting the outbreak of VPD or VPD prevalence in both infant and adult homeless populations published between 1980 and 2020, using PubMed/Medline, SciELO, Google Scholar, and Web of Science databases. Relevant information from the studies was charted in Microsoft Excel and results were summarised using a descriptive analytical method. Results: Eighty-one articles were included. A high prevalence of past hepatitis B virus (HBV) and hepatitis A virus (HAV) infections were observed through serosurveys, mostly in high income countries or high-middle income countries (USA, Canada, France, Iran or Brazil). Ten outbreaks of HAV infection were also reported, with lethality rates ranging from 0 to 4.8%. The studies identified numerous risk factors positively associated with HBV infection, including older age, homosexual or bisexual practice, injected drug use (IDU), and, with HAV infection including IDU, having sexual partner(s) with a history of unspecified hepatitis, insertive anal penetration, or originating from a country with a high prevalence of anti-HAV antibody. Eleven outbreaks of pneumococcal infection affecting PEH were reported in Canada and USA, with lethality rates from 0 to 15.6%. Six diphtheria outbreaks were reported. Vaccination status was rarely documented in these studies. Conclusions: The literature suggests that homeless populations generally experience a high VPD burden suggesting the need for a national vaccination programme and planning for delivering vaccines in this population.
MeSH term(s)	Adult ; Aged ; Brazil ; Canada ; France ; Homeless Persons ; Humans ; Iran ; Tuberculosis/epidemiology ; Tuberculosis/prevention & control ; Vaccine-Preventable Diseases
Language	English
Publishing date	2021-01-26
Publishing country	Netherlands
Document type	Journal Article ; Review ; Systematic Review
ZDB-ID	605674-x
ISSN	1873-2518 ; 0264-410X
ISSN (online)	1873-2518
ISSN	0264-410X
DOI	10.1016/j.vaccine.2021.01.035
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Zs.A 1930: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 458: Show issues

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Article ; Online: Respiratory pathogens among ill pilgrims and the potential benefit of using point-of-care rapid molecular diagnostic tools during the Hajj.

Hoang, Van-Thuan / Dao, Thi-Loi / Ly, Tran Duc Anh / Drali, Tassadit / Yezli, Saber / Parola, Philippe / Pommier de Santi, Vincent / Gautret, Philippe

Acta microbiologica et immunologica Hungarica

2022 Volume 69, Issue 4, Page(s) 283–289

Abstract: We investigated respiratory pathogens among ill Hajj pilgrims from Marseille. We also discuss the potential role of point-of-care (POC) rapid molecular diagnostic tools for this purpose. Clinical data were collected using a standardised questionnaire. ... ...

Abstract	We investigated respiratory pathogens among ill Hajj pilgrims from Marseille. We also discuss the potential role of point-of-care (POC) rapid molecular diagnostic tools for this purpose. Clinical data were collected using a standardised questionnaire. Influenza A and B viruses, human rhinovirus and human coronaviruses, Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae and Klebsiella pneumoniae were investigated using real-time PCR in respiratory samples obtained during travel, at the onset of symptoms. 207 participants were included. A cough, expectoration, rhinitis and a sore throat were the most frequent respiratory symptoms, followed by loss of voice and dyspnoea. 38.7% and 25.1% of pilgrims reported a fever and influenza-like symptoms, respectively. 59.4% pilgrims received antibiotics. Rhinovirus (40.6%) was the most frequent pathogen, followed by S. aureus (35.8%) and H. influenzae (30.4%). Virus and bacteria co-infections were identified in 28.5% of participants. 25.1% pilgrims who were positive for respiratory bacteria did not receive antibiotic treatment. In the context of the Hajj pilgrimage, it is important to detect infections that can be easily managed with appropriate treatment, and those that can affect prognosis, requiring hospitalisation. POC rapid molecular diagnostic tools could be used for patient management at small Hajj medical missions and to rationalise antibiotic consumption among Hajj pilgrims.
MeSH term(s)	Humans ; Pathology, Molecular ; Point-of-Care Systems ; Staphylococcus aureus/genetics ; Influenza, Human
Language	English
Publishing date	2022-11-11
Publishing country	Hungary
Document type	Journal Article
ZDB-ID	918256-1
ISSN	1588-2640 ; 1217-8950
ISSN (online)	1588-2640
ISSN	1217-8950
DOI	10.1556/030.2022.01895
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Zs.A 618: Show issues

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Article ; Online: Corrigendum to "Risk factors for symptoms of infection and microbial carriage among French medical students abroad" [International Journal of Infectious Diseases, Vol 100 (2020) Pages 104-111].

Dao, Thi Loi / Canard, Naomie / Hoang, Van Thuan / Ly, Tran Duc Anh / Drali, Tassadit / Ninove, Laetitia / Fenollar, Florence / Raoult, Didier / Parola, Philippe / Marty, Pierre / Gautret, Philippe

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

2023 Volume 134, Page(s) 153

Language	English
Publishing date	2023-06-24
Publishing country	Canada
Document type	Published Erratum
ZDB-ID	1331197-9
ISSN	1878-3511 ; 1201-9712
ISSN (online)	1878-3511
ISSN	1201-9712
DOI	10.1016/j.ijid.2023.06.012
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Article ; Online: Corrigendum to "Infectious disease symptoms and microbial carriage among French medical students travelling abroad: A prospective study" [Travel Med Infect Dis 34 (2020 Mar-Apr) 101548].

Dao, Thi Loi / Hoang, Van Thuan / Ly, Tran Duc Anh / Magmoun, Amal / Canard, Naomie / Drali, Tassadit / Fenollar, Florence / Ninove, Laetitia / Raoult, Didier / Parola, Philippe / Courjon, Johan / Gautret, Philippe

Travel medicine and infectious disease

2023 Volume 54, Page(s) 102609

Language	English
Publishing date	2023-08-08
Publishing country	Netherlands
Document type	Published Erratum
ZDB-ID	2170891-5
ISSN	1873-0442 ; 1477-8939
ISSN (online)	1873-0442
ISSN	1477-8939
DOI	10.1016/j.tmaid.2023.102609
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Article ; Online: Corrigendum to "Acquisition of multidrug-resistant bacteria and colistin resistance genes in French medical students on internships abroad" [Travel Med Infect Dis. 39 (2021 Jan-Feb) 101940].

Dao, Thi Loi / Hoang, Van Thuan / Magmoun, Amal / Ly, Tran Duc Anh / Baron, Sophie Alexandra / Hadjadj, Linda / Canard, Naomie / Drali, Tassadit / Gouriet, Frédérique / Raoult, Didier / Parola, Philippe / Marty, Pierre / Rolain, Jean-Marc / Gautret, Philippe

Travel medicine and infectious disease

2023 Volume 54, Page(s) 102610

Language	English
Publishing date	2023-08-08
Publishing country	Netherlands
Document type	Published Erratum
ZDB-ID	2170891-5
ISSN	1873-0442 ; 1477-8939
ISSN (online)	1873-0442
ISSN	1477-8939
DOI	10.1016/j.tmaid.2023.102610
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Article: Molecular investigation and genetic diversity of Pediculus and Pthirus lice in France

Amanzougaghene, Nadia / Mediannikov, Oleg / Ly, Tran Duc Anh / Gautret, Philippe / Davoust, Bernard / Fenollar, Florence / Izri, Arezki

Parasites & vectors. 2020 Dec., v. 13, no. 1

2020

Abstract: BACKGROUND: Humans are parasitized by three types of lice: body, head and pubic lice. As their common names imply, each type colonizes a specific region of the body. The body louse is the only recognized disease vector. However, an increasing awareness ... ...

Abstract	BACKGROUND: Humans are parasitized by three types of lice: body, head and pubic lice. As their common names imply, each type colonizes a specific region of the body. The body louse is the only recognized disease vector. However, an increasing awareness of head lice as a vector has emerged recently whereas the status of pubic lice as a vector is not known since it has received little attention. METHODS: Here, we assessed the occurrence of bacterial pathogens in 107 body lice, 33 head lice and 63 pubic lice from Marseille and Bobigny (France) using molecular methods. RESULTS: Results show that all body lice samples belonged to the cytb Clade A whereas head lice samples belonged to Clades A and B. DNA of Bartonella quintana was detected in 7.5% of body lice samples and, for the first time to our knowledge, in 3.1% of pubic lice samples. Coxiella burnetii, which is not usually associated with transmission by louse, was detected in 3.7% of body lice samples and 3% of head lice samples. To the best of our knowledge, this is the first report of C. burnetii in Pediculus lice infesting humans in France. Acinetobacter DNA was detected in 21.5% of body lice samples, 6% of head lice samples and 9.5% of pubic lice samples. Five species were identified with A. baumannii being the most prevalent. CONCLUSIONS: Our study is the first to report the presence of B. quintana in pubic lice. This is also the first report of the presence of DNA of C. burnetii in body lice and head lice in France. Further efforts on the vectorial role of human lice are needed, most importantly the role of pubic lice as a disease vector should be further investigated.
Keywords	Acinetobacter baumannii ; Bartonella quintana ; Coxiella burnetii ; DNA ; Pediculus humanus capitis ; Pthirus pubis ; common names ; disease vectors ; genetic variation ; humans ; lice ; parasitism ; pathogens ; France
Language	English
Dates of publication	2020-12
Size	p. 177.
Publishing place	BioMed Central
Document type	Article
ZDB-ID	2409480-8
ISSN	1756-3305
ISSN	1756-3305
DOI	10.1186/s13071-020-04036-y
Database	NAL-Catalogue (AGRICOLA)

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