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Article ; Online: Letter to the editor: Prescription right ensuring nurses to reach their fullest potential.

Lyu, Qiyuan / Zeng, Yingchun

International journal of nursing sciences

2021 Volume 8, Issue 2, Page(s) 245

Language	English
Publishing date	2021-03-19
Publishing country	China
Document type	Journal Article
ZDB-ID	2800296-9
ISSN	2352-0132 ; 2352-0132
ISSN (online)	2352-0132
ISSN	2352-0132
DOI	10.1016/j.ijnss.2021.03.009
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Article ; Online: Development and validation of a risk prediction model for frailty in patients with diabetes.

Bu, Fan / Deng, Xiao-Hui / Zhan, Na-Ni / Cheng, Hongtao / Wang, Zi-Lin / Tang, Li / Zhao, Yu / Lyu, Qi-Yuan

BMC geriatrics

2023 Volume 23, Issue 1, Page(s) 172

Abstract: Background: Frailty is the third most common complication of diabetes after macrovascular and microvascular complications. The aim of this study was to develop a validated risk prediction model for frailty in patients with diabetes.: Methods: The ... ...

Abstract	Background: Frailty is the third most common complication of diabetes after macrovascular and microvascular complications. The aim of this study was to develop a validated risk prediction model for frailty in patients with diabetes. Methods: The research used data from the China Health and Retirement Longitudinal Study (CHARLS), a dataset representative of the Chinese population. Twenty-five indicators, including socio-demographic variables, behavioral factors, health status, and mental health parameters, were analyzed in this study. The study cohort was randomly divided into a training set and a validation set at a ratio of 70 to 30%. LASSO regression analysis was used to screen the variables for the best predictors of the model based on a 10-fold cross-validation. The logistic regression model was applied to explore the associated factors of frailty in patients with diabetes. A nomogram was constructed to develop the prediction model. Calibration curves were applied to evaluate the accuracy of the nomogram model. The area under the receiver operating characteristic curve and decision curve analysis were conducted to assess predictive performance. Results: One thousand four hundred thirty-six patients with diabetes from the CHARLS database collected in 2013 (n = 793) and 2015 (n = 643) were included in the final analysis. A total of 145 (10.9%) had frailty symptoms. Multivariate logistic regression analysis showed that marital status, activities of daily living, waist circumference, cognitive function, grip strength, social activity, and depression as predictors of frailty in people with diabetes. These factors were used to construct the nomogram model, which showed good concordance and accuracy. The AUC values of the predictive model and the internal validation set were 0.912 (95%CI 0.887-0.937) and 0.881 (95% CI 0.829-0.934). Hosmer-Lemeshow test values were P = 0.824 and P = 0.608 (both > 0.05). Calibration curves showed significant agreement between the nomogram model and actual observations. ROC and DCA indicated that the nomogram had a good predictive performance. Conclusions: Comprehensive nomogram constructed in this study was a promising and convenient tool to evaluate the risk of frailty in patients with diabetes, and contributed clinicians to screening the high-risk population.
MeSH term(s)	Humans ; Activities of Daily Living ; Frailty/diagnosis ; Frailty/epidemiology ; Longitudinal Studies ; Diabetes Mellitus/diagnosis ; Diabetes Mellitus/epidemiology
Chemical Substances	teloxantrone (96521WL61B)
Language	English
Publishing date	2023-03-27
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2059865-8
ISSN	1471-2318 ; 1471-2318
ISSN (online)	1471-2318
ISSN	1471-2318
DOI	10.1186/s12877-023-03823-3
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Article ; Online: Interaction effect of midday napping duration and depressive symptoms on subjective memory impairment among older people in China: evidence from the China health and retirement longitudinal study database.

Tang, Li / Wang, Ya-Qi / Zhan, Na-Ni / Li, Can-Yang / Zhuang, Zhuang / Lyu, Qi-Yuan / Xiong, Peng

BMC public health

2023 Volume 23, Issue 1, Page(s) 1995

Abstract: Background: Subjective memory impairment (SMI) is common in older people. The aim of this study was to investigate the factors influencing SMI among older people in China, with specific focus on the interaction effect of midday napping duration and ... ...

Abstract	Background: Subjective memory impairment (SMI) is common in older people. The aim of this study was to investigate the factors influencing SMI among older people in China, with specific focus on the interaction effect of midday napping duration and depressive symptoms on the risk of SMI. Methods: Using a dataset representative of the Chinese population from a longitudinal study of health and retirement in China, subjects with SMI were screened using the question "how do you feel about your memory now?" and the Mini-Mental State Examination. A logistic regression model was applied to explore the factors affecting SMI. Additive and multiplicative models were used to analyze the interaction effect of midday napping duration and depressive symptoms on the risk of SMI. Results: We enrolled 8,254 subjects included and the incidence of SMI was 63.9%. Depressive symptoms, nap time, and physical activity were influencing factors of SMI. Midday napping duration and depressive symptoms had positive additive interaction effects on the risk of SMI. When extended-length naps and depressive symptoms coexisted, the risk of SMI was 1.06 times greater than that for either alone (RERI, relative excess risk due to interaction = 0.27, 95% CI = 0.07-0.43; AP, attributable proportion = 0.14, 95% CI = 0.01-0.23; S, synergy index = 1.06, 95% CI = 0.57-1.62). When short naps and depressive symptoms coexisted, the risk of SMI was 1.2 times higher than that for either alone (RERI = 0.12, 95% CI=-0.14-0.39; AP = 0.13, 95% CI=-0.07-0.22; S = 1.20, 95% CI = 0.79-1.82). Limitations: Since this was a cross-sectional study, the cause-and-effect relationships between the associated variables cannot be inferred. Conclusions: The interaction effect that exists between nap time and depressive symptoms in older people is important for the identification and early intervention of people at risk for SMI.
MeSH term(s)	Humans ; Aged ; Longitudinal Studies ; Risk Factors ; Depression/epidemiology ; Retirement ; Cross-Sectional Studies ; Sleep ; China/epidemiology
Language	English
Publishing date	2023-10-13
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2041338-5
ISSN	1471-2458 ; 1471-2458
ISSN (online)	1471-2458
ISSN	1471-2458
DOI	10.1186/s12889-023-16928-6
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Article ; Online: Effect of a fall within three months of admission on delirium in critically Ill elderly patients: a population-based cohort study.

Bu, Fan / Cheng, Hong-Tao / Wang, Zi-Lin / Hou, Yu-Shan / Zhuang, Zhuang / Li, Can-Yang / Wang, Ya-Qi / Zhang, Yue / Lyu, Jun / Lyu, Qi-Yuan

Aging clinical and experimental research

2024 Volume 36, Issue 1, Page(s) 111

Abstract: Background: Delirium is common among elderly patients in the intensive care unit (ICU) and is associated with prolonged hospitalization, increased healthcare costs, and increased risk of death. Understanding the potential risk factors and early ... ...

Abstract	Background: Delirium is common among elderly patients in the intensive care unit (ICU) and is associated with prolonged hospitalization, increased healthcare costs, and increased risk of death. Understanding the potential risk factors and early prevention of delirium is critical to facilitate timely intervention that may reverse or mitigate the harmful consequences of delirium. Aim: To clarify the effects of pre-admission falls on ICU outcomes, primarily delirium, and secondarily pressure injuries and urinary tract infections. Methods: The study relied on data sourced from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database. Statistical tests (Wilcoxon rank-sum or chi-squared) compared cohort characteristics. Logistic regression was employed to investigate the association between a history of falls and delirium, as well as secondary outcomes, while Kaplan-Meier survival curves were used to assess short-term survival in delirium and non-delirium patients. Results: Study encompassed 22,547 participants. Delirium incidence was 40%, significantly higher in patients with a history of falls (54.4% vs. 34.5%, p < 0.001). Logistic regression, controlling for confounders, not only confirmed that a history of falls elevates the odds of delirium (OR: 2.11; 95% CI: 1.97-2.26; p < 0.001) but also showed it increases the incidence of urinary tract infections (OR:1.50; 95% CI:1.40-1.62; p < 0.001) and pressure injuries (OR:1.36; 95% CI:1.26-1.47; p < 0.001). Elderly delirium patients exhibited lower 30-, 180-, and 360-day survival rates than non-delirium counterparts (all p < 0.001). Conclusions: The study reveals that history of falls significantly heighten the risk of delirium and other adverse outcomes in elderly ICU patients, leading to decreased short-term survival rates. This emphasizes the critical need for early interventions and could inform future strategies to manage and prevent these conditions in ICU settings.
MeSH term(s)	Humans ; Delirium/epidemiology ; Aged ; Accidental Falls/statistics & numerical data ; Female ; Male ; Critical Illness ; Aged, 80 and over ; Intensive Care Units ; Cohort Studies ; Risk Factors ; Hospitalization ; Incidence ; Urinary Tract Infections/epidemiology
Language	English
Publishing date	2024-05-14
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2104785-6
ISSN	1720-8319 ; 1594-0667
ISSN (online)	1720-8319
ISSN	1594-0667
DOI	10.1007/s40520-024-02740-8
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Article ; Online: Self-esteem and family functioning mediates the association of symptom severity and parental affiliate stigma among families with children with ASD.

Lyu, Qi-Yuan / Yu, Xiao-Xue / Wang, Jia-le / Wang, Xin-Yu / Ke, Qi-Qi / Liu, Dan / Yang, Qiao-Hong

Journal of pediatric nursing

2022 Volume 66, Page(s) e122–e129

Abstract: Purpose: To investigate the level of affiliate stigma among parents of children with autism spectrum disorder and to explore the mediating role of self-esteem and family functioning.: Design and methods: A cross-sectional study was conducted in a ... ...

Abstract	Purpose: To investigate the level of affiliate stigma among parents of children with autism spectrum disorder and to explore the mediating role of self-esteem and family functioning. Design and methods: A cross-sectional study was conducted in a large regional hospital and two childhood rehabilitation centers in Guangdong, China. Data related to demographics, parental self-esteem, family functioning, and affiliate stigma were collected from 180 parents of children diagnosed with ASD. We used t-tests, analysis of variance, and correlation analysis to explore the related factors of parental affiliate stigma. Path analysis was used to determine the mediating roles of self-esteem and family functioning in the relationship between symptom severity and affiliate stigma. Results: Parents of children with autism spectrum disorder in China experienced low self-esteem, family functioning, and high affiliate stigma. Symptom severity was negatively correlated with self-esteem and family functioning. Self-esteem and family functioning were significantly negatively correlated with affiliate stigma. Symptom severity was positively correlated with affiliate stigma. Self-esteem and family functioning mediated the relationship between symptom severity and affiliate stigma. Conclusions: Symptom severity affects parental affiliate stigma among families with children with ASD. Self-esteem and family functioning are the two mediators in the relationship. We should take steps to improve self-esteem and family functioning in order to alleviate parental affiliate stigma. Practice implications: This study emphasizes the importance of the influence of ASD severity and family functioning on affiliate stigma. In clinical practice, psychological support should be provided for parents of children with ASD to improve their mental health.
MeSH term(s)	Autism Spectrum Disorder ; Child ; Cross-Sectional Studies ; Humans ; Parents ; Self Concept ; Social Stigma
Language	English
Publishing date	2022-05-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	632731-x
ISSN	1532-8449 ; 0882-5963
ISSN (online)	1532-8449
ISSN	0882-5963
DOI	10.1016/j.pedn.2022.04.019
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Zs.B 2871: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Association between bidirectional intergenerational support and successful aging in China: Evidence from CHARLS 2018.

Zhao, Yu / Tang, Li / Zeng, Qing-Wei / Bu, Fan / Zhan, Na-Ni / Wang, Zi-Lin / Deng, Xiao-Hui / Lyu, Qi-Yuan

Geriatric nursing (New York, N.Y.)

2022 Volume 49, Page(s) 81–88

Abstract: Aging has gradually accelerated in China, and achieving successful aging of older adults has become a public health concern. Intergenerational support is crucial for Chinese older adults in later life due to the culture of filial piety. However, the ... ...

Abstract	Aging has gradually accelerated in China, and achieving successful aging of older adults has become a public health concern. Intergenerational support is crucial for Chinese older adults in later life due to the culture of filial piety. However, the association between successful aging and intergenerational support remains poorly understood in China. This study aimed to examine the association between patterns of intergenerational support and successful aging of older adults in China. The present study is a secondary analysis of data obtained from the follow-up survey of the China Health and Retirement Longitudinal Study 2018. Data were analyzed using descriptive statistics and logistic regressions. Bidirectional intergenerational support was associated with successful aging in the participants. In addition, there was an association between different intergenerational financial, caring, and emotional support patterns and elements of successful aging.
MeSH term(s)	Humans ; Aged ; Longitudinal Studies ; Aging ; Retirement ; Surveys and Questionnaires ; China ; Intergenerational Relations
Language	English
Publishing date	2022-11-28
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	632559-2
ISSN	1528-3984 ; 0197-4572
ISSN (online)	1528-3984
ISSN	0197-4572
DOI	10.1016/j.gerinurse.2022.11.010
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Article ; Online: Health literacy and quality of life of patients with coronary heart disease in Tibet, China: The mediating role of self-efficacy and self-management.

Liu, An-Kang / Liu, Yu-Yao / Su, Jin / Gao, Jing / Dong, Li-Juan / Lyu, Qi-Yuan / Yang, Qiao-Hong

Heart & lung : the journal of critical care

2022 Volume 57, Page(s) 271–276

Abstract: Background: The disease burden of coronary heart disease patients in Tibet, China, ranks high in the country. Due to the local culture and environment, patients with coronary heart disease have increased risk factors for the disease, and their survival ... ...

Abstract	Background: The disease burden of coronary heart disease patients in Tibet, China, ranks high in the country. Due to the local culture and environment, patients with coronary heart disease have increased risk factors for the disease, and their survival is worrisome. Objectives: The purpose of this study was to determine the relationship between health literacy and quality of life for patients with coronary heart disease in Tibet, China, and to explore the mediating roles of self-efficacy and self-management. Methods: A cross-sectional study was conducted from August 2020 to July 2021 in Tibet. A total of 258 patients with coronary heart disease in Tibet participated. Self-reported questionnaires were used to assess health literacy, self-efficacy, self-management, and quality of life. Pearson correlation analysis and the SPSS PROCESS macro were used to analyze the data. Results: The mean total score for the health literacy of patients with coronary heart disease in Tibet was 3.59 ± 0.80 points, showing the existence of a limited level of literacy. The quality of life was of an average level, with scores of 57.20 ± 21.70 points and 63.63 ± 20.66 points for physical and mental status, respectively. Self-efficacy and self-management mediated the relationship between health literacy and quality of life. Conclusions: Self-efficacy and self-management mediate the relationship between health literacy and quality of life. Targeted interventions for health literacy, self-efficacy, and self-management skills are important to improve the quality of life of Tibetan patients with coronary heart disease.
MeSH term(s)	Humans ; Health Literacy ; Quality of Life ; Self Efficacy ; Self-Management ; Tibet/epidemiology ; Cross-Sectional Studies ; Surveys and Questionnaires ; Coronary Disease/epidemiology ; China/epidemiology
Language	English
Publishing date	2022-10-29
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	193129-5
ISSN	1527-3288 ; 0147-9563
ISSN (online)	1527-3288
ISSN	0147-9563
DOI	10.1016/j.hrtlng.2022.10.009
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Article: A self-administered immersive virtual reality tool for assessing cognitive impairment in patients with cancer.

Zeng, Yingchun / Guan, Qiongyao / Su, Yan / Huang, Qiubo / Zhao, Jun / Wu, Minghui / Guo, Qiaohong / Lyu, Qiyuan / Zhuang, Yiyu / Cheng, Andy Sk

Asia-Pacific journal of oncology nursing

2023 Volume 10, Issue 3, Page(s) 100205

Abstract: Objective: This study was aimed at exploring the feasibility and validity of a self-administered immersive virtual reality (VR) tool designed to assess cognitive impairment in patients with cancer.: Methods: In a cross-sectional survey study, an ... ...

Abstract	Objective: This study was aimed at exploring the feasibility and validity of a self-administered immersive virtual reality (VR) tool designed to assess cognitive impairment in patients with cancer. Methods: In a cross-sectional survey study, an immersive tool was used to rate the previously recommended core assessment domains of cancer-related cognitive impairment-comprising attention, verbal learning memory, processing speed, executive function and verbal fluency-via an interactive VR scenario. Results: A total of 165 patients with cancer participated in this study. The participants' mean age was 47.74 years (SD = 10.59). Common cancer types included lung, liver, breast and colorectal cancer, and most patients were in early disease stages ( Conclusions: Given its demonstrated validity, and the patients' high presence scores and minimal sickness scores, this VR-based cognition assessment tool is a feasible and acceptable instrument for measuring cognitive impairment in patients with cancer. However, further psychometric assessments should be implemented in clinical settings.
Language	English
Publishing date	2023-02-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	2984639-0
ISSN	2349-6673 ; 2347-5625
ISSN (online)	2349-6673
ISSN	2347-5625
DOI	10.1016/j.apjon.2023.100205
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Article ; Online: Perceived Family Impact During Children's Hospitalization for Treatment of Acute Lymphoblastic Leukemia: A Cross-sectional Study.

Lyu, Qi-Yuan / Wong, Frances K Y / You, Li-Ming / Li, Xian-Wen

Cancer nursing

2020 Volume 43, Issue 6, Page(s) 489–497

Abstract: Background: Improved survival rates of acute lymphoblastic leukemia (ALL) in children are often associated with repeated and prolonged hospitalization, creating an immensely stressful situation for the family.: Objective: The aims of this study were ... ...

Abstract	Background: Improved survival rates of acute lymphoblastic leukemia (ALL) in children are often associated with repeated and prolonged hospitalization, creating an immensely stressful situation for the family. Objective: The aims of this study were to assess perceived family impact and coping during the child's hospitalization for ALL treatment and identify potential predictors of perceived family impact. Interventions/methods: A total of 212 families with children hospitalized participated. The hospitalization impact and coping scales were used to assess perceived family impact and coping, respectively. Results: The mean (SD) total score for perceived family impact was 88.11 (22.39); social impact received the highest average score. The mean (SD) total score for family coping was 39.02 (9.84). A significant decrease in family coping was associated with more readmissions. Predictors of perceived family impact were severity of the child's illness, total days of all admissions, and coping, accounting for 37% of the observed variance. Conclusions: Families were moderately affected by children's hospitalizations; social functioning was most affected. Families' perceived coping effectiveness decreased as the readmissions increased. The higher risk category a child's diagnosis is, the longer a child's hospitalization is, and the less perceived coping effectiveness, the higher family perceived impact. Implications for practice: The findings provide a direction for the development of family-centered supportive intervention programs. Nurses should be aware that the total days of admission and severity of a child's illness are significant factors associated with perceived family impact and likely justify special attention. Family coping enhancement interventions could alleviate perceived family impact.
MeSH term(s)	Adaptation, Psychological ; Adolescent ; Adult ; Child ; Child, Preschool ; Cross-Sectional Studies ; Family/psychology ; Female ; Hong Kong ; Hospitalization ; Hospitals, Pediatric ; Humans ; Infant ; Male ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/psychology ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/therapy ; Socioeconomic Factors ; Stress, Psychological
Language	English
Publishing date	2020-10-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	391995-x
ISSN	1538-9804 ; 0162-220X
ISSN (online)	1538-9804
ISSN	0162-220X
DOI	10.1097/NCC.0000000000000720
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Article ; Online: Factors Associated With Colorectal Cancer Screening Among First-Degree Relatives of Patients With Colorectal Cancer in China.

Du, Qianqian / Chen, Jingyu / Meng, Ya / Gong, Ni / Wu, Xiaodan / Lyu, Qiyuan / Zhang, Yiheng / Wu, Xiaoyu / Zhang, Meifen

Cancer nursing

2021 Volume 45, Issue 2, Page(s) E447–E453

Abstract: Background: First-degree relatives of patients with colorectal cancer have an elevated risk of colorectal cancer. However, the behavior and factors potential influencing first-degree relatives regarding colorectal cancer screening in China remain ... ...

Abstract	Background: First-degree relatives of patients with colorectal cancer have an elevated risk of colorectal cancer. However, the behavior and factors potential influencing first-degree relatives regarding colorectal cancer screening in China remain unknown. Objective: The aim of this study was to explore the screening behavior and related factors of first-degree relatives of colorectal cancer patients. Methods: A cross-sectional design was applied, and 201 first-degree relatives participated from August 2018 to July 2019. Data were collected about demographic information, the "Colorectal Cancer Perceptions Scale," and screening behavior of first-degree relatives. Factors associated with screening behavior were identified using logistic regression analysis. Results: Only 18.9% of first-degree relatives had participated in colonoscopy screening. Two Health Belief Model factors were the influencing factors of their participation in colorectal cancer screening. Higher possibility of colorectal cancer screening of first-degree relatives was associated with higher perceived susceptibility (odds ratio, 1.224; 95% confidence interval, 1.075-1.395) and lower perception of barriers (odds ratio, 0.880; 95% confidence interval, 0.820-0.944) of first-degree relatives. Conclusions: Participation in colorectal cancer screening by first-degree relatives requires improvement; perceived susceptibility and perception of barriers were the most important predictors. Implications for practice: Health professionals can enhance awareness of colorectal cancer susceptibility and address barriers to colorectal cancer screening among first-degree relatives at both individual and social levels.
MeSH term(s)	Colonoscopy ; Colorectal Neoplasms/diagnosis ; Colorectal Neoplasms/genetics ; Colorectal Neoplasms/prevention & control ; Cross-Sectional Studies ; Early Detection of Cancer ; Humans ; Mass Screening
Language	English
Publishing date	2021-07-23
Publishing country	United States
Document type	Journal Article
ZDB-ID	391995-x
ISSN	1538-9804 ; 0162-220X
ISSN (online)	1538-9804
ISSN	0162-220X
DOI	10.1097/NCC.0000000000000985
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