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Article ; Online: Pharmacogenetic variants influence vitamin K anticoagulant dosing in patients with mechanical prosthetic heart valves.

Koshy, Linda / Vb, Raghu / M, Madhuma / Ben, Midhuna P / Kishor, Pritam / Sudhakaran, P R / Abdullakutty, Jabir / Venugopal, K / Zachariah, Geevar / Mohanan, P P / Harikrishnan, S / G, Sanjay

Pharmacogenomics

2022  Volume 23, Issue 8, Page(s) 475–485

Abstract: Background: ...

Abstract Background:
MeSH term(s) Anticoagulants ; Cytochrome P-450 CYP2C9/genetics ; Genotype ; Heart Valves/surgery ; Humans ; Pharmacogenomic Variants ; Polymorphism, Single Nucleotide ; Vitamin K ; Vitamin K Epoxide Reductases/genetics
Chemical Substances Anticoagulants ; Vitamin K (12001-79-5) ; Cytochrome P-450 CYP2C9 (EC 1.14.13.-) ; VKORC1 protein, human (EC 1.17.4.4) ; Vitamin K Epoxide Reductases (EC 1.17.4.4)
Language English
Publishing date 2022-05-24
Publishing country England
Document type Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID 2019513-8
ISSN 1744-8042 ; 1462-2416
ISSN (online) 1744-8042
ISSN 1462-2416
DOI 10.2217/pgs-2022-0014
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Zs.A 5247: Show issues Location:
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