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  1. AU="Márquez-Sánchez, M T"
  2. AU="Remy, Séverine"
  3. AU="van der Stoel, Miesje M"
  4. AU="Hifumi, Toru"
  5. AU="Jie Chen"
  6. AU="Ballarin, Barbara"
  7. AU="Thiel, Nadine"
  8. AU="Gerti Pishtari"
  9. AU="Alexander Hammers, ProfPhD"
  10. AU="Dessimoz, Christophe"
  11. AU="Planchuelo-Gómez, Álvaro"
  12. AU="McKay, Lindsay G A"
  13. AU="Laude, Marie-Charlotte"
  14. AU="Hale, Lillian V A"
  15. AU="Hassan Hartman"
  16. AU="Song, Mengwei"
  17. AU="Yimin Geng"
  18. AU="Wang, Chang-Sheng"
  19. AU="Doyle, Andrew D"
  20. AU="Redpath, Sophie H A"
  21. AU="Hopman, Maria Te"
  22. AU="Pomputius, William"
  23. AU="Agrawal, Sonali"
  24. AU="Martinez, Luis R"
  25. AU="Passoni, Lorena"
  26. AU="Slimani, Wafa"
  27. AU="Jin, J"
  28. AU="Xia, Hongmin"
  29. AU="Akdemir, İrem"
  30. AU=Ciccone Giovannino

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  1. Artikel ; Online: The impact of psychiatric pathology on the prognosis and survival of men with prostate cancer undergoing radical prostatectomy.

    Cózar-Ortiz, J D / Cózar-Olmo, J M / Álvarez-Ossorio-Fernández, J L / Esteban-Fuertes, M / Chantada-Abal, V / Valverde-Martínez, L S / Márquez-Sánchez, M T / Padilla-Fernández, B Y / Lorenzo-Gómez, M F

    Actas urologicas espanolas

    2022  Band 46, Heft 10, Seite(n) 646–652

    Abstract: Introduction and objective: Cancer-specific anxiety is the most frequently reported psychological response after radical prostatectomy (RP). We evaluated the prevalence of pretreatment psychiatric pathology in patients with prostate cancer undergoing RP ...

    Abstract Introduction and objective: Cancer-specific anxiety is the most frequently reported psychological response after radical prostatectomy (RP). We evaluated the prevalence of pretreatment psychiatric pathology in patients with prostate cancer undergoing RP and identified the effects of psychiatric diagnoses on their survival and prognosis.
    Material and methods: Retrospective multicenter observational study including 1078 men treated with RP for organ-confined prostate cancer. Groups: GP: patients with psychiatric pathology prior to RP; GNP: patients without psychiatric pathology prior to RP. Urological, oncological and psychiatric variables, descriptive statistics and multivariate analysis were included.
    Results: 37.94% of patients presented a psychiatric diagnosis. Adjuvant radiotherapy was required in 27.83% and hormone therapy in 23.38%; being more frequent in GP. Cancer-specific survival was higher in GNP. Anxiety, depression, insomnia, smoking, psychosis and alcoholism were the most frequent. Low TNM and low presence of LUTS and SUI increased the probability of absence of psychiatric pathology. Fatigue, erectile dysfunction and cognitive impairment after RP with RT and/or HT were higher in GP. Older age and higher PSA at diagnosis increased the relative risk of psychiatric pathology and worse outcome. The most frequently related factors were RP, PSA, age and survival time.
    Conclusions: Psychiatric pathology is present in patients undergoing radical prostatectomy for prostate cancer, with a high impact on survival and prognostic outcomes.
    Mesh-Begriff(e) Humans ; Male ; Prostatic Neoplasms/surgery
    Sprache Spanisch
    Erscheinungsdatum 2022-10-20
    Erscheinungsland Spain
    Dokumenttyp Multicenter Study ; Observational Study ; Journal Article
    ISSN 2173-5786
    ISSN (online) 2173-5786
    DOI 10.1016/j.acuroe.2022.10.003
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Impact of organ confined prostate cancer treatment on quality of life.

    Alvarez-Ossorio-Rodal, A / Padilla-Fernandez, B / Muller-Arteaga, C A / Miglioni, F / Alvarez-Ossorio-Fernandez, J L / Valverde-Martínez, S / Marquez-Sanchez, M T / Flores-Fraile, M C / Linares-Mesa, N A / Miron-Canelo, J A / Garcia-Cenador, M B / Lorenzo-Gomez, M F

    Actas urologicas espanolas

    2020  Band 44, Heft 9, Seite(n) 630–636

    Abstract: Introduction: Prostate cancer (PCa) is the second most common male cancer in the world. Its incidence is estimated to grow to 1.7 million new cases and 499,000 new deaths by 2030. Treatment of OCPC can affect patients physically and mentally, as well as ...

    Titelübersetzung Impacto en la calidad de vida del tratamiento del cáncer de próstata organoconfinado.
    Abstract Introduction: Prostate cancer (PCa) is the second most common male cancer in the world. Its incidence is estimated to grow to 1.7 million new cases and 499,000 new deaths by 2030. Treatment of OCPC can affect patients physically and mentally, as well as their close relationships and their job or career, which conditions health-related quality of life (QoL).
    Objective: Evaluate the impact on QoL attributable to the treatment for Organ Confined Prostate Cancer (OCPC).
    Materials and methods: Prospective multicenter observational study of 406 patients with OCPC treated from January 2015 to June 2018. The sample was divided into four study groups, according to the type of treatment: radical prostatectomy (RP) (GA), external radiotherapy (ERT) (GB), brachytherapy (BT) (GC) and other treatments different from monotherapy with RP, ERT or BT (GD).
    Results: The age in GC was lower, the mean Prostate Specific Antigen (PSA) of all patients was 8.13 ng/ml, the group with the highest mean PSA was GB with a mean of 10.43 ng/dL, the mean Tumor Stage (TNM) was 3.82, and GD had the lowest post treatment quality of life.
    Conclusion: OCPC treatment affects QoL. Curative monotherapies, specifically RP and BT, have less effect on QoL than external radiotherapy or other therapeutic alternatives. Urinary incontinence and fistulas secondary to OCPC have the highest impact on QOL impairment. The internationally validated SF 36 questionnaire is a useful cross-sectional measure of QOL to compare the impact of OCPC treatment modalities.
    Mesh-Begriff(e) Aged ; Humans ; Male ; Middle Aged ; Prospective Studies ; Prostatic Neoplasms/pathology ; Prostatic Neoplasms/therapy ; Quality of Life
    Sprache Spanisch
    Erscheinungsdatum 2020-09-17
    Erscheinungsland Spain
    Dokumenttyp Journal Article ; Multicenter Study ; Observational Study ; Research Support, Non-U.S. Gov't
    ISSN 2173-5786
    ISSN (online) 2173-5786
    DOI 10.1016/j.acuro.2020.05.002
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: The influence of smoking on bacterial resistance after vaccine or antibiotic prophylaxis against recurrent urinary tract infections.

    Lorenzo-Gómez, M F / Santos-Antunes, M T / Nieto-Huertos, A / Lorenzo-Gómez, A / Marquez-Sanchez, M T / Flores-Fraile, M C / Valverde-Martinez, L S / González-Casado, I / García-Cenador, M B / Mirón-Canelo, J A / Padilla-Fernández, B

    Actas urologicas espanolas

    2020  Band 44, Heft 7, Seite(n) 497–504

    Abstract: Introduction: The influence of tobacco on the microbiological spectrum, resistance-sensitivity pattern and evolution in patients with recurrent urinary tract infections (RUTI) is analyzed. Evaluation of the effect of polyvalent bacterial vaccine on the ... ...

    Titelübersetzung Influencia del tabaquismo en la resistencia bacteriana después de la profilaxis frente a infecciones urinarias recurrentes con antibiótico o con vacuna.
    Abstract Introduction: The influence of tobacco on the microbiological spectrum, resistance-sensitivity pattern and evolution in patients with recurrent urinary tract infections (RUTI) is analyzed. Evaluation of the effect of polyvalent bacterial vaccine on the prevention of RUTI and smoking status.
    Material and methods: Retrospective multicenter study of 855 women with RUTI receiving suppressive antibiotic treatment or bacterial vaccine between 2009 and 2013. Group A (GA): Antibiotic (n=495); Subgroups: GA1 non-smoker (n=417), GA2 smoker (n=78). Group B (GB): Vaccine (n=360); Subgroups: GB1 non-smoker (n=263), GB2 smoker (n=97).
    Variables: Age, pre-treatment UTI, disease-free time (DFT), microbial species, sensitivity and resistance. Follow-up at 3, 6 and 12 months with culture and SF-36 questionnaire.
    Results: Mean age 56.51 years (18-75), similar between groups (P=.2257). No difference in the number of pretreatment UTIs (P=.1329) or in the distribution of the bacterial spectrum (P=.7471). DFT was higher in subgroups B compared with A. Urine cultures in GA1: E. coli 62.71% with 8.10% resistance (33% quinolones; 33% cotrimoxazole; 33% quinolones + cotrimoxazole); in GA2 E. coli 61.53% with 75% resistance (16.66% quinolones; 33.33% quinolones + cotrimoxazole; 16.66% amoxicillin-clavulanate; 16.66% erythromycin + phosphomycin + clindamycin) (P=.0133). There were no differences between patients of GA treated with cotrimoxazole and nitrofurantoin (P=.8724). Urine cultures in GB1: E. coli 47.36% with 22.22% resistance (5.55% ciprofloxacin; 5.55% cotrimoxazole; 5.55% ciprofloxacin + cotrimoxazole; 5.55% amoxicillin/clavulanic acid). In GB2 E. coli 70.02% with 61.90% resistances (30.76% quinolones; 30.76% cotrimoxazole; 30.76% quinolones + cotrimoxazole; 17.69% amoxicillin-clavulanic acid) (P=.0144).
    Conclusions: The development of bacterial resistance is more frequent among women with smoking habits and recurrent urinary infections. This could influence a worse response to preventive treatments, either with antibiotics or vaccines.
    Mesh-Begriff(e) Adolescent ; Adult ; Aged ; Antibiotic Prophylaxis ; Bacterial Infections/drug therapy ; Bacterial Infections/prevention & control ; Bacterial Vaccines ; Drug Resistance, Bacterial ; Female ; Humans ; Middle Aged ; Recurrence ; Retrospective Studies ; Smoking/adverse effects ; Urinary Tract Infections/drug therapy ; Urinary Tract Infections/microbiology ; Young Adult
    Chemische Substanzen Bacterial Vaccines
    Sprache Spanisch
    Erscheinungsdatum 2020-06-25
    Erscheinungsland Spain
    Dokumenttyp Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
    ISSN 2173-5786
    ISSN (online) 2173-5786
    DOI 10.1016/j.acuro.2020.04.002
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Volltext online

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