LIVIVO - Search results -

Search results

Result 1 - 10 of total 46

Search options

Article: Challenges in Septic Shock: From New Hemodynamics to Blood Purification Therapies.

Ramasco, Fernando / Nieves-Alonso, Jesús / García-Villabona, Esther / Vallejo, Carmen / Kattan, Eduardo / Méndez, Rosa

2024 Volume 14, Issue 2

Abstract: Sepsis and septic shock are associated with high mortality, with diagnosis and treatment remaining a challenge for clinicians. Their management classically encompasses hemodynamic resuscitation, antibiotic treatment, life support, and focus control; ... ...

Abstract	Sepsis and septic shock are associated with high mortality, with diagnosis and treatment remaining a challenge for clinicians. Their management classically encompasses hemodynamic resuscitation, antibiotic treatment, life support, and focus control; however, there are aspects that have changed. This narrative review highlights current and avant-garde methods of handling patients experiencing septic shock based on the experience of its authors and the best available evidence in a context of uncertainty. Following the first recommendation of the Surviving Sepsis Campaign guidelines, it is recommended that specific sepsis care performance improvement programs are implemented in hospitals, i.e., "Sepsis Code" programs, designed ad hoc, to achieve this goal. Regarding hemodynamics, the importance of perfusion and hemodynamic coherence stand out, which allow for the recognition of different phenotypes, determination of the ideal time for commencing vasopressor treatment, and the appropriate fluid therapy dosage. At present, this is not only important for the initial timing, but also for de-resuscitation, which involves the early weaning of support therapies, directed elimination of fluids, and fluid tolerance concept. Finally, regarding blood purification therapies, those aimed at eliminating endotoxins and cytokines are attractive in the early management of patients in septic shock.
Language	English
Publishing date	2024-02-03
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2662248-8
ISSN	2075-4426
ISSN	2075-4426
DOI	10.3390/jpm14020176
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article: Sepsis Stewardship: The Puzzle of Antibiotic Therapy in the Context of Individualization of Decision Making.

Ramasco, Fernando / Méndez, Rosa / Suarez de la Rica, Alejandro / González de Castro, Rafael / Maseda, Emilio

Journal of personalized medicine

2024 Volume 14, Issue 1

Abstract: The main recent change observed in the field of critical patient infection has been universal awareness of the need to make better use of antimicrobials, especially for the most serious cases, beyond the application of simple and effective formulas or ... ...

Abstract	The main recent change observed in the field of critical patient infection has been universal awareness of the need to make better use of antimicrobials, especially for the most serious cases, beyond the application of simple and effective formulas or rigid protocols. The increase in resistant microorganisms, the quantitative increase in major surgeries and interventional procedures in the highest risk patients, and the appearance of a significant number of new antibiotics in recent years (some very specifically directed against certain mechanisms of resistance and others with a broader spectrum of applications) have led us to shift our questions from "what to deal with" to "how to treat". There has been controversy about how best to approach antibiotic treatment of complex cases of sepsis. The individualized and adjusted dosage, the moment of its administration, the objective, and the selection of the regimen are pointed out as factors of special relevance in a critically ill patient where the frequency of resistant microorganisms, especially among the Enterobacterales group, and the emergence of multiple and diverse antibiotic treatment alternatives have made the appropriate choice of antibiotic treatment more complex, requiring a constant updating of knowledge and the creation of multidisciplinary teams to confront new infections that are difficult to treat. In this article, we have reviewed the phenomenon of the emergence of resistance to antibacterials and we have tried to share some of the ideas, such as stewardship, sparing carbapenems, and organizational, microbiological, pharmacological, and knowledge tools, that we have considered most useful and effective for individualized decision making that takes into account the current context of multidrug resistance. The greatest challenge, therefore, of decision making in this context lies in determining an effective, optimal, and balanced empirical antibiotic treatment.
Language	English
Publishing date	2024-01-18
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2662248-8
ISSN	2075-4426
ISSN	2075-4426
DOI	10.3390/jpm14010106
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Decrease in Mortality after the Implementation of a Hospital Model to Improve Performance in Sepsis Care: Princess Sepsis Code.

Méndez, Rosa / Figuerola, Angels / Ramasco, Fernando / Chicot, Marta / Pascual, Natalia F / García, Íñigo / von Wernitz, Andrés / Zurita, Nelly D / Semiglia, Auxiliadora / Pizarro, Alberto / Saez, Carmen / Rodríguez, Diego

Journal of personalized medicine

2024 Volume 14, Issue 2

Abstract: Sepsis is a time-dependent disease whose prognosis is influenced by early diagnosis and therapeutic measures. Mortality from sepsis remains high, and for this reason, the guidelines of the Surviving Sepsis Campaign recommend establishing specific care ... ...

Abstract	Sepsis is a time-dependent disease whose prognosis is influenced by early diagnosis and therapeutic measures. Mortality from sepsis remains high, and for this reason, the guidelines of the Surviving Sepsis Campaign recommend establishing specific care programs aimed at patients with sepsis. We present the results of the application of a hospital model to improve performance in sepsis care, called
Language	English
Publishing date	2024-01-29
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662248-8
ISSN	2075-4426
ISSN	2075-4426
DOI	10.3390/jpm14020149
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Removal of tetracyclines from swine manure at full-scale activated sludge treatment plants.

Montes, Nuria / Otero, Marta / Coimbra, Ricardo N / Méndez, Rosa / Martín-Villacorta, Javier

Environmental technology

2015 Volume 36, Issue 13-16, Page(s) 1966–1973

Abstract: The purpose of this study was to investigate the fate of three tetracyclines (TCs), namely oxytetracycline (OTC), chlortetracycline (CTC) and doxycycline (DC) at two different full-scale swine manure-activated sludge treatment plants. Throughout ... ...

Abstract	The purpose of this study was to investigate the fate of three tetracyclines (TCs), namely oxytetracycline (OTC), chlortetracycline (CTC) and doxycycline (DC) at two different full-scale swine manure-activated sludge treatment plants. Throughout treatment, OTC, CTC and DC were removed by 71-76%, 75-80% and 95%, respectively. Removal of these TCs under physical treatment was deniable. On the contrary, the flocculation-coagulation and the secondary clarification resulted in a relevant reduction of the concentration of these TCs.
MeSH term(s)	Animals ; Environmental Pollutants/chemistry ; Environmental Pollutants/isolation & purification ; Environmental Restoration and Remediation/methods ; Flocculation ; Manure/analysis ; Refuse Disposal/methods ; Sewage/analysis ; Sewage/chemistry ; Swine ; Tetracyclines/chemistry ; Tetracyclines/isolation & purification
Chemical Substances	Environmental Pollutants ; Manure ; Sewage ; Tetracyclines
Language	English
Publishing date	2015-07
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	0959-3330
ISSN	0959-3330
DOI	10.1080/09593330.2015.1018338
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Criterios de triaje para reanimación cardiopulmonar y soporte vital avanzado durante la epidemia COVID-19

Real de Asúa, Diego / Galván, Jose María / Iglesias, Judit / Fernández, Julia / Rodríguez, Diego / Albert, Patricia / Méndez, Rosa / Alonso, Tamara / Churruca, María / Salamanca, Jorge / Retana, Bárbara / Casals, Fernando / García, Íñigo / Canabal, Alfonso

Medicina Clínica

Keywords	covid19
Publisher	Elsevier
Document type	Article ; Online
DOI	10.1016/j.medcli.2020.04.009
Database	COVID19

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article ; Online: Zinc Absorption from Fortified Milk Powder in Adolescent Girls.

Méndez, Rosa O / Hambidge, Michael / Baker, Mark / Salgado, Sergio A / Ruiz, Joaquín / García, Hugo S / Calderón de la Barca, Ana M

Biological trace element research

2015 Volume 168, Issue 1, Page(s) 61–66

Abstract: Zinc (Zn) is essential for development, growth, and reproduction. The Mexican government subsidizes micronutrient-fortified milk for risk groups, with positive effect on the targeted groups' plasma Zn level, inferring a good absorption is achieved ... ...

Abstract	Zinc (Zn) is essential for development, growth, and reproduction. The Mexican government subsidizes micronutrient-fortified milk for risk groups, with positive effect on the targeted groups' plasma Zn level, inferring a good absorption is achieved although it has not being measured. The aim of this study was to determine the impact of micronutrient-fortified milk intake during 27 days on Zn absorption in adolescent girls from northwest Mexico. Therefore, Zn absorption was evaluated in 14 healthy adolescent girls (14.1 years old) with adequate plasma Zn levels, before and after 27 days of fortified Zn milk intake. Fractional Zn absorption (FZA) was calculated from urinary ratios of stable isotopic Zn tracers administered orally and intravenously on days 0 and 27, and total absorbed Zn (TZA) was calculated. At the beginning, Zn intake was 6.8 ± 0.85 mg/d (mean ± SE), and 50 % of the adolescent girls did not achieve their requirement (7.3 mg/d). Additionally, FZA was negatively correlated with Zn intake (r =-0.61, p = 0.02), while TZA (1.06 mg/d) was insufficient to cover the physiologic requirements of adolescent girls (3.02 mg/d). At the end of the intervention, all the girls reached the Zn intake recommendation and TZA, 3.09 mg/d, which was enough to meet the physiological requirement for 57 % of the adolescent girls. Therefore, the low Zn intake and the Zn status of adolescent girls were positively impacted by Zn-fortified milk intake and its good absorption rate.
MeSH term(s)	Adolescent ; Animals ; Dairy Products ; Diet ; Female ; Food, Fortified ; Humans ; Intestinal Absorption ; Mexico ; Milk/metabolism ; Zinc/pharmacokinetics ; Zinc/urine ; Zinc Isotopes
Chemical Substances	Zinc Isotopes ; Zinc (J41CSQ7QDS)
Language	English
Publishing date	2015-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	445336-0
ISSN	1559-0720 ; 0163-4984
ISSN (online)	1559-0720
ISSN	0163-4984
DOI	10.1007/s12011-015-0356-x
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.B 2323: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Zinc fortification decreases ZIP1 gene expression of some adolescent females with appropriate plasma zinc levels.

Méndez, Rosa O / Santiago, Alejandra / Yepiz-Plascencia, Gloria / Peregrino-Uriarte, Alma B / de la Barca, Ana M Calderón / García, Hugo S

Nutrients

2014 Volume 6, Issue 6, Page(s) 2229–2239

Abstract: Zinc homeostasis is achieved after intake variation by changes in the expression levels of zinc transporters. The aim of this study was to evaluate dietary intake (by 24-h recall), absorption, plasma zinc (by absorption spectrophotometry) and the ... ...

Abstract	Zinc homeostasis is achieved after intake variation by changes in the expression levels of zinc transporters. The aim of this study was to evaluate dietary intake (by 24-h recall), absorption, plasma zinc (by absorption spectrophotometry) and the expression levels (by quantitative PCR), of the transporters ZIP1 (zinc importer) and ZnT1 (zinc exporter) in peripheral white blood cells from 24 adolescent girls before and after drinking zinc-fortified milk for 27 day. Zinc intake increased (p < 0.001) from 10.5 ± 3.9 mg/day to 17.6 ± 4.4 mg/day, and its estimated absorption from 3.1 ± 1.2 to 5.3 ± 1.3 mg/day. Mean plasma zinc concentration remained unchanged (p > 0.05) near 150 µg/dL, but increased by 31 µg/dL (p < 0.05) for 6/24 adolescents (group A) and decreased by 25 µg/dL (p < 0.05) for other 6/24 adolescents (group B). Expression of ZIP1 in blood leukocytes was reduced 1.4-fold (p < 0.006) in group A, while for the expression of ZnT1 there was no difference after intervention (p = 0.39). An increase of dietary zinc after 27-days consumption of fortified-milk did not increase (p > 0.05) the plasma level of adolescent girls but for 6/24 participants from group A in spite of the formerly appropriation, which cellular zinc uptake decreased as assessed by reduction of the expression of ZIP1.
MeSH term(s)	Adolescent ; Animals ; Cation Transport Proteins/genetics ; Cation Transport Proteins/metabolism ; Child ; Female ; Food, Fortified ; Gene Expression Regulation/drug effects ; Homeostasis ; Humans ; Milk/chemistry ; Zinc/administration & dosage ; Zinc/blood
Chemical Substances	Cation Transport Proteins ; SLC30A1 protein, human ; SLC39A1 protein, human ; Zinc (J41CSQ7QDS)
Language	English
Publishing date	2014-06-11
Publishing country	Switzerland
Document type	Clinical Trial ; Journal Article
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu6062229
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Zinc Fortification Decreases ZIP1 Gene Expression of Some Adolescent Females with Appropriate Plasma Zinc Levels

Méndez, Rosa O / Santiago, Alejandra / Yepiz-Plascencia, Gloria / Peregrino-Uriarte, Alma B / Barca, Ana M. Calderón de la / García, Hugo S

Nutrients. 2014 June 11, v. 6, no. 6

2014

Abstract	Zinc homeostasis is achieved after intake variation by changes in the expression levels of zinc transporters. The aim of this study was to evaluate dietary intake (by 24-h recall), absorption, plasma zinc (by absorption spectrophotometry) and the expression levels (by quantitative PCR), of the transporters ZIP1 (zinc importer) and ZnT1 (zinc exporter) in peripheral white blood cells from 24 adolescent girls before and after drinking zinc-fortified milk for 27 day. Zinc intake increased (p < 0.001) from 10.5 ± 3.9 mg/day to 17.6 ± 4.4 mg/day, and its estimated absorption from 3.1 ± 1.2 to 5.3 ± 1.3 mg/day. Mean plasma zinc concentration remained unchanged (p > 0.05) near 150 μg/dL, but increased by 31 μg/dL (p < 0.05) for 6/24 adolescents (group A) and decreased by 25 μg/dL (p < 0.05) for other 6/24 adolescents (group B). Expression of ZIP1 in blood leukocytes was reduced 1.4-fold (p < 0.006) in group A, while for the expression of ZnT1 there was no difference after intervention (p = 0.39). An increase of dietary zinc after 27-days consumption of fortified-milk did not increase (p > 0.05) the plasma level of adolescent girls but for 6/24 participants from group A in spite of the formerly appropriation, which cellular zinc uptake decreased as assessed by reduction of the expression of ZIP1.
Keywords	absorption ; adolescents ; blood plasma ; drinking ; females ; food intake ; fortified foods ; gene expression ; girls ; homeostasis ; leukocytes ; milk ; quantitative polymerase chain reaction ; spectroscopy ; transporters ; zinc
Language	English
Dates of publication	2014-0611
Size	p. 2229-2239.
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2518386-2
ISSN	2072-6643
ISSN	2072-6643
DOI	10.3390/nu6062229
Database	NAL-Catalogue (AGRICOLA)

Order via subito

Article ; Online: Criterios de triaje para reanimación cardiopulmonar y soporte vital avanzado durante la epidemia COVID-19

Real de Asúa, Diego / Galván, Jose María / Iglesias, Judit / Fernández, Julia / María Galván, Jose / Diego Rodríguez / Albert, Patricia / Méndez, Rosa / Alonso, Tamara / Churruca, María / Salamanca, Jorge / Retana, Bárbara / Casals, Fernando / García, Íñigo / Canabal, Alfonso

Medicina Clínica

2020 Volume 155, Issue 5, Page(s) 215–219

Keywords	General Medicine ; covid19
Language	Spanish
Publisher	Elsevier BV
Publishing country	us
Document type	Article ; Online
ZDB-ID	411607-0
ISSN	1578-8989 ; 0025-7753
ISSN (online)	1578-8989
ISSN	0025-7753
DOI	10.1016/j.medcli.2020.04.009
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

In stock of ZB MED Cologne/Königswinter

Ua VI Zs.279: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Could giardiasis be a risk factor for low zinc status in schoolchildren from northwestern Mexico? A cross-sectional study with longitudinal follow-up.

Quihui, Luis / Morales, Gloria G / Méndez, Rosa O / Leyva, Johanna G / Esparza, Julián / Valencia, Mauro E

BMC public health

2010 Volume 10, Issue 1, Page(s) 85

Abstract: Background: Both giardiasis and zinc deficiency are serious health problems worldwide. In Mexico, the prevalence of G. intestinalis was estimated at 32% in 1994. It remains a health problem in northwestern Mexico. Recent surveys (1987, 1995, and 1999) ... ...

Abstract	Background: Both giardiasis and zinc deficiency are serious health problems worldwide. In Mexico, the prevalence of G. intestinalis was estimated at 32% in 1994. It remains a health problem in northwestern Mexico. Recent surveys (1987, 1995, and 1999) reported zinc deficiency in the Mexican population. The association of giardiasis and malabsorption of micronutrients has been well documented, although the association with zinc remains controversial. This study investigated the association between giardiasis and zinc deficiency in schoolchildren from northwestern Mexico. Methods: We combined a cross-sectional design with a longitudinal follow-up six months after parasite treatment. The baseline sample consisted of 114 schoolchildren (mean age 8.8 yr) from seven suburban public schools, grouped as Giardia-free (n = 65, 57%) and Giardia-infected (n = 49, 43%). Three stool analyses per child were done using Faust's method. Children with giardiasis received secnidazole. Serum zinc was determined by atomic absorption spectrophotometry. Height and weight were measured. Socioeconomic information was obtained in an oral questionnaire, and daily zinc intake was assessed using 24 hour-recalls. Pearson's correlation and ANCOVA and paired t-test analyses were used to determine the association between giardiasis and zinc status. Results: Longitudinal analysis demonstrated a significant increase of the mean serum zinc levels in the Giardia-infected group six months after treatment (13.78 vs. 19.24 mumol/L mumol/L; p = 0.001), although no difference was found between the Giardia-free and the Giardia-infected groups (p = 0.86) in the baseline analysis. Z scores for W/A and H/A were lower in the Giardia-infected than in the Giardia-free group (p < 0.05). No difference was observed in the socioeconomic characteristics and mean daily intakes of zinc between the groups (p > 0.05). Conclusions: Giardiasis may be a risk factor for zinc deficiency in schoolchildren from northwestern Mexico.
MeSH term(s)	Antiprotozoal Agents/therapeutic use ; Child ; Cross-Sectional Studies ; Deficiency Diseases/etiology ; Female ; Follow-Up Studies ; Giardiasis/complications ; Giardiasis/drug therapy ; Humans ; Male ; Metronidazole/analogs & derivatives ; Metronidazole/therapeutic use ; Mexico ; Nutritional Status ; Schools ; Socioeconomic Factors ; Surveys and Questionnaires ; Zinc/blood ; Zinc/deficiency
Chemical Substances	Antiprotozoal Agents ; Metronidazole (140QMO216E) ; Zinc (J41CSQ7QDS) ; secnidazole (R3459K699K)
Language	English
Publishing date	2010-02-20
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1471-2458
ISSN (online)	1471-2458
DOI	10.1186/1471-2458-10-85
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED