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  1. Book ; Thesis: Infektionsrisiko durch Schimmelpilze im Wohnbereich bei immunbeeinträchtigten Personen

    Müller, Dominik

    2018  

    Author's details vorgelegt von Dominik Müller
    Language German
    Size VII, 137, vi Blätter, Diagramme, 30 cm
    Publishing place Freiburg i. Br
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Albert-Ludwigs-Universität Freiburg i. Br., 2018
    HBZ-ID HT020173625
    Database Catalogue ZB MED Medicine, Health

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  2. Book ; Thesis: Die Bedeutung von gastrointestinalen und metabolischen Erkrankungen für die Komposition und Stabilität der Darmmikrobiota

    Frost, Fabian Burkhard / Völker, Uwe / Bruns, Tony / Müller, Dominik N.

    2021  

    Institution Universität Greifswald
    Author's details vorgelegt von Dr. med. Fabian Burkhard Frost ; 1. Gutachter: Prof. Dr. rer. nat. Uwe Völker, Greifswald, 2. Gutachter: Prof. Dr. med. habil. Tony Bruns, Aachen, 3. Gutachter: Prof. Dr. rer. nat. Dominik N. Müller, Berlin
    Language German ; English
    Size 26 Seiten, 54 ungezählte Seiten, Illustrationen (farbig), Diagramme (farbig)
    Publishing place Greifswald
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Habilitationsschrift, Universitätsmedizin der Universität Greifswald, 2021
    Note Literaturverzeichnis: Seite 21-25. - Literaturangaben
    HBZ-ID HT021297083
    Database Catalogue ZB MED Medicine, Health

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  3. Book ; Thesis: Effekt einer transendokardialen, kathetergestützten Injektion von Stromal cell derived factor 1 alpha auf die myokardiale Perfusion im chronischen Herzinfarktmodell im Schwein

    Müller, Dominik

    2014  

    Author's details vorgelegt von Dominik Müller
    Language German
    Size 66 S. : Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Aachen, Techn. Hochsch., Diss., 2014
    HBZ-ID HT018284640
    Database Catalogue ZB MED Medicine, Health

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  4. Book ; Thesis: Analyse der Apoptose-induzierenden Wirkung des Notch-Antagonisten Hairless in Drosophila melanogaster (Meigen)

    Müller, Dominik

    (Berichte aus der Biologie)

    2005  

    Author's details Dominik Müller
    Series title Berichte aus der Biologie
    Keywords Taufliege ; Apoptosis ; Signaltransduktion ; Gen notch
    Subject Notch ; Notch-Rezeptor ; Notch-Signalweg ; Signalübertragung ; Signalvermittlung ; Apoptose ; Programmierter Zelltod ; Drosophila fasciata ; Drosophila melanogaster ; Kleine Essigfliege ; Kleine Obstfliege ; Kleine Taufliege
    Language German
    Size IX, 169 S., Ill., graph. Darst., 21 cm, 275 gr.
    Publisher Shaker
    Publishing place Aachen
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Hohenheim, Univ., Diss., 2005
    Note Zsfassung in engl. Sprache
    HBZ-ID HT014999664
    ISBN 3-8322-4724-6 ; 978-3-8322-4724-9
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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  5. Article: Behandle deinen Patienten und nicht Covid-19!

    Müller, Dominik

    Allgemeine Homöopathische Zeitung

    2021  Volume 266, Issue 01, Page(s) 21–38

    Abstract: Die homöopathischen Behandlungsverläufe (ambulant / stationär) von 4 Patienten, die sich mit Covid-19 infiziert haben, werden vorgestellt. Wichtige Aspekte wie die Häufigkeit von Follow-ups, Erfassung von Vitalparametern, Möglichkeiten der Arzneiwahl, ... ...

    Abstract Die homöopathischen Behandlungsverläufe (ambulant / stationär) von 4 Patienten, die sich mit Covid-19 infiziert haben, werden vorgestellt. Wichtige Aspekte wie die Häufigkeit von Follow-ups, Erfassung von Vitalparametern, Möglichkeiten der Arzneiwahl, Differenzialdiagnose, Potenzhöhe und Häufigkeit der Arzneigabe werden diskutiert.
    Keywords Covid-19 ; Homöopathie ; Pneumonie ; Hochpotenz ; Komplementärmedizin ; Covid-19 ; homeopathy ; pneumonia ; high potency ; complementary medicine
    Language German
    Publishing date 2021-01-01
    Publisher Karl F. Haug Verlag in Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2124175-2
    ISSN 1439-8990 ; 1438-2563
    ISSN (online) 1439-8990
    ISSN 1438-2563
    DOI 10.1055/a-1312-2952
    Database Thieme publisher's database

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  6. Article ; Online: Urinary Acidification Does Not Explain the Absence of Nephrocalcinosis in a Mouse Model of Familial Hypomagnesaemia with Hypercalciuria and Nephrocalcinosis (FHHNC).

    Al-Shebel, Amr / Michel, Geert / Breiderhoff, Tilman / Müller, Dominik

    International journal of molecular sciences

    2024  Volume 25, Issue 3

    Abstract: Patients with mutations ... ...

    Abstract Patients with mutations in
    MeSH term(s) Humans ; Animals ; Mice ; Hypercalciuria/genetics ; Nephrocalcinosis/genetics ; Calcium ; Salts ; Magnesium ; Hydrogen-Ion Concentration ; Claudins/genetics
    Chemical Substances Calcium (SY7Q814VUP) ; Salts ; Magnesium (I38ZP9992A) ; Claudins
    Language English
    Publishing date 2024-02-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25031779
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: MIScnn: a framework for medical image segmentation with convolutional neural networks and deep learning.

    Müller, Dominik / Kramer, Frank

    BMC medical imaging

    2021  Volume 21, Issue 1, Page(s) 12

    Abstract: Background: The increased availability and usage of modern medical imaging induced a strong need for automatic medical image segmentation. Still, current image segmentation platforms do not provide the required functionalities for plain setup of medical ...

    Abstract Background: The increased availability and usage of modern medical imaging induced a strong need for automatic medical image segmentation. Still, current image segmentation platforms do not provide the required functionalities for plain setup of medical image segmentation pipelines. Already implemented pipelines are commonly standalone software, optimized on a specific public data set. Therefore, this paper introduces the open-source Python library MIScnn.
    Implementation: The aim of MIScnn is to provide an intuitive API allowing fast building of medical image segmentation pipelines including data I/O, preprocessing, data augmentation, patch-wise analysis, metrics, a library with state-of-the-art deep learning models and model utilization like training, prediction, as well as fully automatic evaluation (e.g. cross-validation). Similarly, high configurability and multiple open interfaces allow full pipeline customization.
    Results: Running a cross-validation with MIScnn on the Kidney Tumor Segmentation Challenge 2019 data set (multi-class semantic segmentation with 300 CT scans) resulted into a powerful predictor based on the standard 3D U-Net model.
    Conclusions: With this experiment, we could show that the MIScnn framework enables researchers to rapidly set up a complete medical image segmentation pipeline by using just a few lines of code. The source code for MIScnn is available in the Git repository: https://github.com/frankkramer-lab/MIScnn .
    MeSH term(s) Deep Learning ; Humans ; Image Processing, Computer-Assisted/methods ; Kidney Neoplasms/diagnostic imaging ; Neural Networks, Computer ; Software Design ; Software Validation
    Language English
    Publishing date 2021-01-18
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2061975-3
    ISSN 1471-2342 ; 1471-2342
    ISSN (online) 1471-2342
    ISSN 1471-2342
    DOI 10.1186/s12880-020-00543-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book ; Thesis: Analyse des Patientenguts der Herztransplantations-Warteliste

    Müller, Dominik

    klinische Parameter und Untersuchungsergebnisse

    1998  

    Author's details vorgelegt von Dominik Müller
    Language German
    Size 77 S. : graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Frankfurt (Main), Univ., Diss., 1999
    HBZ-ID HT012767641
    Database Catalogue ZB MED Medicine, Health

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  9. Article ; Online: Potentielle Nephrotoxizität der Kombinationstherapie von Vancomycin und Piperacillin-Tazobactam: Empfehlungen der AG ABS der DGPI unter Beteiligung von Experten der GPN.

    Martin, Luise / Pecar, Alenka / Baltaci, Yeliz / Simon, Arne / Kohl, Stefan / Müller, Dominik / Forster, Johannes

    Klinische Padiatrie

    2024  

    Abstract: The combination of vancomycin and piperacillin/tazobactam (V+P/T) is used for empirical antibiotic treatment of severe infections, especially in immunocompromised patients and those colonized with multidrug-resistant bacteria. Nephrotoxicity is a ... ...

    Title translation Potential Nephrotoxicity of Combination of Vancomycin and Piperacillin-Tazobactam: Recommendations from the AG ABS of the DGPI supported by experts of the GPN.
    Abstract The combination of vancomycin and piperacillin/tazobactam (V+P/T) is used for empirical antibiotic treatment of severe infections, especially in immunocompromised patients and those colonized with multidrug-resistant bacteria. Nephrotoxicity is a frequently observed adverse effect of vancomycin. Its risk can be reduced by therapeutic drug monitoring and adjusted dosing. Piperacillin/tazobactam (P/T) rarely causes interstitial nephritis. The results of retrospective cohort studies in children predominantly show a low, clinically irrelevant, additive nephrotoxicity (defined as an increase in creatinine in the serum) of both substances. Due to the limitations of the existing publications, the ABS working group of the DGPI and experts of the GPN do not recommend against the use of P/T plus vancomycin. Preclinical studies and a prospective study with adult patients, which evaluated different renal function tests as well as clinical outcomes, do not support previous findings of additive nephrotoxicity. Time-restricted use of V+P/T can minimize exposure and the potential risk of nephrotoxicity. Local guidelines, developed in collaboration with the antibiotic stewardship team, should define the indications for empirical and targeted use of P/T and V+P/T. When using combination therapy with V+P/T, kidney function should be monitored through clinical parameters (volume status, balancing, blood pressure) as well as additional laboratory tests such as serum creatinine and cystatin C.
    Language German
    Publishing date 2024-03-08
    Publishing country Germany
    Document type English Abstract ; Journal Article
    ZDB-ID 120650-3
    ISSN 1439-3824 ; 0300-8630
    ISSN (online) 1439-3824
    ISSN 0300-8630
    DOI 10.1055/a-2244-7698
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Salt sensitivity includes effects on immune cell signalling and metabolism.

    Müller, Dominik N / Geisberger, Sabrina / Kleinewietfeld, Markus / Jantsch, Jonathan

    Nature reviews. Immunology

    2023  Volume 23, Issue 6, Page(s) 341–342

    MeSH term(s) Humans ; Sodium Chloride/pharmacology ; Signal Transduction ; Hypertension
    Chemical Substances Sodium Chloride (451W47IQ8X)
    Language English
    Publishing date 2023-04-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 2062776-2
    ISSN 1474-1741 ; 1474-1733
    ISSN (online) 1474-1741
    ISSN 1474-1733
    DOI 10.1038/s41577-023-00881-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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