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Article ; Online: Evolving pharmacy profession around the globe towards an improved health care

Abdulbaset A. Elfituri / Fathi M. Sherif

Iberoamerican Journal of Medicine, Vol 2, Iss 3, Pp 140-

2020 Volume 141

Keywords	pharmacy ; medicine ; health care ; Medicine (General) ; R5-920
Language	English
Publishing date	2020-04-01T00:00:00Z
Publisher	Emergency Department of Hospital San Pedro (Logroño, Spain)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: RNAi-Based Biofungicides as a Promising Next-Generation Strategy for Controlling Devastating Gray Mold Diseases

Md Tabibul Islam / Sherif M. Sherif

International Journal of Molecular Sciences, Vol 21, Iss 6, p

2020 Volume 2072

Abstract: Botrytis cinerea is one of the most critical agro-economic phytopathogens and has been reported to cause gray mold disease in more than 1000 plant species. Meanwhile, small interfering RNA (siRNA), which induce RNA interference (RNAi), are involved in ... ...

Abstract	Botrytis cinerea is one of the most critical agro-economic phytopathogens and has been reported to cause gray mold disease in more than 1000 plant species. Meanwhile, small interfering RNA (siRNA), which induce RNA interference (RNAi), are involved in both host immunity and pathogen virulence. B. cinerea has been reported to use both siRNA effectors and host RNAi machinery to facilitate the progression of gray mold in host species. Accordingly, RNAi-based biofungicides that use double-stranded RNA (dsRNA) to target essential fungal genes are considered an emerging approach for controlling devastating gray mold diseases. Furthermore, spray-induced gene silencing (SIGS), in which the foliar application of dsRNA is used to silence the pathogen virulence genes, holds great potential as an alternative to host-induced gene silencing (HIGS). Recently, SIGS approaches have attracted research interest, owing to their ability to mitigate both pre- and post-harvest B. cinerea infections. The RNAi-mediated regulation of host immunity and susceptibility in B. cinerea −host interactions are summarized in this review, along with the limitations of the current knowledge of RNAi-based biofungicides, especially regarding SIGS approaches for controlling gray mold diseases under field conditions.
Keywords	botrytis cinerea ; spray-induced gene silencing ; rnai-based biofungicide ; sirna ; dsrna ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
Subject code	571
Language	English
Publishing date	2020-03-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Synthesizing of Novel Bulk (Zr 67 Cu 33 ) 100-x W x (x; 5-30 at%) Glassy Alloys by Spark Plasma Sintering of Mechanically Alloyed Powders

M. Sherif El-Eskandarany / Naser Ali

Molecules, Vol 25, Iss 1906, p

2020 Volume 1906

Abstract: Metallic glassy alloys with their short-range order have received considerable attention since their discovery in 1960′s. The worldwide interest in metallic glassy alloys is attributed to their unique mechanical, physical, and chemical properties, which ... ...

Abstract	Metallic glassy alloys with their short-range order have received considerable attention since their discovery in 1960′s. The worldwide interest in metallic glassy alloys is attributed to their unique mechanical, physical, and chemical properties, which cannot be found together in long-range order alloys of the same compositions. Traditional preparation methods of metallic glasses, such as rapid solidification of melts, always restrict the formation of glassy alloys with large atomic fraction (above 3–5 at%) of high melting point metals (Ta, Mo, W). In this study, (Zr 67 Cu 33 ) 100 − x W x ( x 5–30 at%) metallic glassy alloys were fabricated through a mechanical alloying approach, which starts from the elemental powders. This system shows excellent glass forming ability in a wide range of W (0 ≤ x ≥ 30 at%). We have proposed a spark plasma sintering technique to prepare nearly full-dense large sized (20 × 20 mm) bulk metallic glassy alloys. The as-consolidated bulk metallic glassy alloys were seen to possess high thermal stability when compared with the other metallic glassy systems. This is implied by their high glass transition temperature (722–735 K), wide range of supercooled liquid region (39 K to over 100 K), and high values of crystallization temperature (761 K to 823 K). In addition, the fabricated ternary systems have revealed high microhardness values.
Keywords	solid-state reaction ; glass forming ability ; metastable phase ; powder consolidation ; thermal stability ; microhardness ; Organic chemistry ; QD241-441
Subject code	669 ; 290
Language	English
Publishing date	2020-04-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Radiological hazard assessments of radionuclides in building materials, soils and sands from the Gaza Strip and the north of Sinai Peninsula

Mona M. Abd Elkader / Taeko Shinonaga / Mohamed M. Sherif

Scientific Reports, Vol 11, Iss 1, Pp 1-

2021 Volume 13

Abstract: Abstract Radiological hazards to the residents of the Gaza Strip, Palestine and the north of the Sinai Peninsula, Egypt, were determined using the naturally occurring radionuclides (226Ra, 232Th and 40K) in 69 samples of building materials (demolition ... ...

Abstract	Abstract Radiological hazards to the residents of the Gaza Strip, Palestine and the north of the Sinai Peninsula, Egypt, were determined using the naturally occurring radionuclides (226Ra, 232Th and 40K) in 69 samples of building materials (demolition debris, plasters, concretes, from recycling plants and raw cements from suppliers), soils and sands collected in the field. The radiological hazard indices and dose rates calculated with the activity concentrations of radionuclides in those materials determined by gamma-ray spectrometry indicate that the values are all within the global limits recommended by the United Nations Scientific Committee on the Effects of Atomic Radiation 2000 and European Commission 1999. The results of Spearman's correlation and hierarchical cluster analysis for 210Pb in the building materials, soils and sands suggest that the samples include 210Pb from the atmospheric fallout. The medium correlation between 232Th and 40K in demolition debris implies that their activity concentrations are characteristic of the building materials and constituents of the demolition debris. Non-natural ratio of 238U/235U was found in the soil and sand samples collected in the Gaza Strip. Furthermore, 137Cs and 241Am were detected in some soil, sand and demolition debris samples analyzed in this study. The origins of those anthropogenic radionuclides were considered.
Keywords	Medicine ; R ; Science ; Q
Subject code	910
Language	English
Publishing date	2021-12-01T00:00:00Z
Publisher	Nature Portfolio
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Effect of partial replacing of wheat by sea buckthorn (Hippophae rhamnoides L.) fruit residues in broiler diets on performance and skin pigmentation

Ziyad T. BenMahmoud / Bashir M. Sherif / Awatef M. Elfituri

Open Veterinary Journal, Vol 11, Iss 4, Pp 780-

2021 Volume 788

Abstract: Background: Improving poultry products is a constant research topic as the poultry industry aims to provide healthy products to consumers at economic prices and achieve financial profits for breeders. Therefore, recent research has resorted to finding ... ...

Abstract	Background: Improving poultry products is a constant research topic as the poultry industry aims to provide healthy products to consumers at economic prices and achieve financial profits for breeders. Therefore, recent research has resorted to finding cheap natural sources as alternatives to traditional feed and antibiotics. Aim: The experiment was conducted to study the effects of sea buckthorn fruit residues meal on broilers' performance and skin pigmentation. Method: A total of 700 broiler chicks (ROSS 308) were allotted into two groups, and each group comprised of 350 birds divided into 10 replicants, 35 birds to each replicant. The experimental group was fed diets where 15% of the wheat was replaced by sea buckthorn residues meal. The control group was fed diets without any color additive. Feed and water were provided ad-libitum. Results: The sea buckthorn fruit residues contained 21% crude protein (CP) and Metabolisable energy calculated (MEn) was 9.88 MJ/kg. The live body weight was significantly lower than the experimental group (P<0.05) on days 14 and 28. The feed conversion ratio was significantly poorer in the experimental group compared with the control group on days 35 of age (P<0.05). The mortality was higher in the experimental group than in the control group. The DSM Broiler Fan assessed skin color. The skin of the broilers was significantly more yellowish in the experimental group than the control group (103.08 vs. 102.38 scales). The pigmentation of the skin was higher in males than females. Conclusion: The use of sea buckthorn residues in poultry feeding negatively affected the overall performance rate. Mightily, its use in diets depends mainly on the price of feed ingredients. Thus, improving the skin color and biological value of broiler meat can determine its usefulness in broiler feed.
Keywords	sea buckthorn residues ; broilers ; performance ; skin pigmentation ; Zoology ; QL1-991
Subject code	571
Language	English
Publishing date	2021-12-01T00:00:00Z
Publisher	Tripoli University
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Impact of Prolonged Exposure of Eleven Years to Hot Seawater on the Degradation of a Thermoset Composite

Amir Hussain Idrisi / Abdel-Hamid I. Mourad / Muhammad M. Sherif

Polymers, Vol 13, Iss 2154, p

2021 Volume 2154

Abstract: This paper presents a long-term experimental investigation of E-glass/epoxy composites’ durability exposed to seawater at different temperatures. The thermoset composite samples were exposed to 23 °C, 45 °C and 65 °C seawater for a prolonged exposure ... ...

Abstract	This paper presents a long-term experimental investigation of E-glass/epoxy composites’ durability exposed to seawater at different temperatures. The thermoset composite samples were exposed to 23 °C, 45 °C and 65 °C seawater for a prolonged exposure time of 11 years. The mechanical performance as a function of exposure time was evaluated and a strength-based technique was used to assess the durability of the composites. The experimental results revealed that the tensile strength of E-glass/epoxy composite was reduced by 8.2%, 29.7%, and 54.4% after immersion in seawater for 11 years at 23 °C, 45 °C, and 65 °C, respectively. The prolonged immersion in seawater resulted in the plasticization and swelling in the composite. This accelerated the rate of debonding between the fibers and matrix. The failure analysis was conducted to investigate the failure mode of the samples. SEM micrographs illustrated a correlation between the fiber/matrix debonding, potholing, fiber pull-out, river line marks and matrix cracking with deterioration in the tensile characteristics of the thermoset composite.
Keywords	E-glass/epoxy composite ; seawater ; durability ; mechanical properties ; microstructural analysis ; Organic chemistry ; QD241-441
Language	English
Publishing date	2021-06-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Fall Applications of Ethephon Modulates Gene Networks Controlling Bud Development during Dormancy in Peach ( Prunus Persica )

Jianyang Liu / Md Tabibul Islam / Suzanne Laliberte / David C. Haak / Sherif M. Sherif

International Journal of Molecular Sciences, Vol 23, Iss 6801, p

2022 Volume 6801

Abstract: Ethephon (ET) is an ethylene-releasing plant growth regulator (PGR) that can delay the bloom time in Prunus, thus reducing the risk of spring frost, which is exacerbated by global climate change. However, the adoption of ET is hindered by its detrimental ...

Abstract	Ethephon (ET) is an ethylene-releasing plant growth regulator (PGR) that can delay the bloom time in Prunus, thus reducing the risk of spring frost, which is exacerbated by global climate change. However, the adoption of ET is hindered by its detrimental effects on tree health. Little knowledge is available regarding the mechanism of how ET shifts dormancy and flowering phenology in peach. This study aimed to further characterize the dormancy regulation network at the transcriptional level by profiling the gene expression of dormant peach buds from ET-treated and untreated trees using RNA-Seq data. The results revealed that ET triggered stress responses during endodormancy, delaying biological processes related to cell division and intercellular transportation, which are essential for the floral organ development. During ecodormancy, ET mainly impeded pathways related to antioxidants and cell wall formation, both of which are closely associated with dormancy release and budburst. In contrast, the expression of dormancy-associated MADS (DAM) genes remained relatively unaffected by ET, suggesting their conserved nature. The findings of this study signify the importance of floral organogenesis during dormancy and shed light on several key processes that are subject to the influence of ET, therefore opening up new avenues for the development of effective strategies to mitigate frost risks.
Keywords	peach ; bud dormancy ; ethylene ; transcriptome ; bloom ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
Subject code	580
Language	English
Publishing date	2022-06-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Synthesis, and characterization of metallic glassy Cu–Zr–Ni powders decorated with big cube Zr2Ni nanoparticles for potential antibiofilm coating applications

Ahmad Aldhameer / M. Sherif El-Eskandarany / Mohmmad Banyan / Fahad Alajmi / Mohamed Kishk

Scientific Reports, Vol 12, Iss 1, Pp 1-

2022 Volume 19

Abstract: Abstract Biofilms, are significant component that contributes to the development of chronic infections, especially when medical devices are involved. This issue offers a huge challenge for the medical community since standard antibiotics are only capable ...

Abstract	Abstract Biofilms, are significant component that contributes to the development of chronic infections, especially when medical devices are involved. This issue offers a huge challenge for the medical community since standard antibiotics are only capable of eradicating biofilms to a very limited degree. The prevention of biofilm formation have led to the development of a variety of coating methods and new materials. These methods are intended to coat surfaces in such a way as to inhibit the formation of biofilm. Metallic glassy alloys, in particular, alloys that include copper and titanium metals have gained popularity as desirable antibacterial coating. Meanwhile, there has been a rise in the use of the cold spray coating technique due to the fact that it is a proper approach for processing temperature-sensitive materials. The present study was carried out in part with the intention of developing a new antibiofilm metallic glassy consisting of ternary Cu–Zr–Ni using mechanical alloying technique. The spherical powders that comprised the end-product were utilized as feedstock materials for cold spray coatings to stainless steel surfaces at low temperature. When compared to stainless steel, substrates coated with metallic glassy were able to significantly reduce the formation of biofilm by at least one log.
Keywords	Medicine ; R ; Science ; Q
Subject code	620
Language	English
Publishing date	2022-08-01T00:00:00Z
Publisher	Nature Portfolio
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Protective effect of vitamin C against thiamethoxam-induced toxicity in male rats

Ibrahim A. Hamed / Refat M. Sherif / El-Sayed A. El-Sheikh / Ahmed M. Aldawek / Aly A. Shalaby

Open Veterinary Journal, Vol 13, Iss 10, Pp 1334-

2023 Volume 1345

Abstract: Background: Thiamethoxam (THM) is a neonicotinoid insecticide used to control different insect pests on fruits, vegetables, and field crops. The misuse and continuous exposure to THM cause many harmful effects on health and the reproductive system. Aim: ... ...

Abstract	Background: Thiamethoxam (THM) is a neonicotinoid insecticide used to control different insect pests on fruits, vegetables, and field crops. The misuse and continuous exposure to THM cause many harmful effects on health and the reproductive system. Aim: This work aims to investigate the efficiency of vitamin C (vit C) in reducing or eliminating the harmful effects of THM on testes, liver, and kidney of male rats. Methods: Forty eight sexually mature male Wister albino rats (weight: 170-190 g; age: 10-11 weeks) randomly allocated into six groups (8 males/group). Control group was orally given distilled water, vit. C group orally treated with 200 mg/kg b.wt of vit C, group 1/10 of THM LD50 orally treated with 156.3 mg/kg b.wt of THM, group 1/20 of THM LD50 orally with 78.15 mg/kg b.wt of THM, group 1/10 of THM LD50 + vit. C orally treated with 156.3 mg/kg b.wt of THM + 200 mg/kg b.wt of vit. C, group 1/20 of THM LD50 + vit. C orally treated with 78.15 mg/kg b.wt of THM + 200 mg/kg b.wt of vit. C. All groups were treated for five days per week for a whole period of 58 days. Blood samples were collected at the end of the experiment and serum was extracted for liver and kidney function and antioxidants measurements. Reproductive organs (testis, epididymis, and seminal vesicles) were collected and weighted in the end of the experiment. Results: The results showed that groups exposed to 1/10 and 1/20 of THM LD50 significantly (p [Open Vet J 2023; 13(10.000): 1334-1345]
Keywords	thiamethoxam ; vitamin c ; oxidative stress ; antioxidant ; Zoology ; QL1-991
Language	English
Publishing date	2023-10-01T00:00:00Z
Publisher	Tripoli University
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Effect of Al 2 O 3 and NiO Nanoparticle Additions on the Structure and Corrosion Behavior of Sn—4% Zn Alloy Coating Carbon Steel

Ghada A. Alshammri / Naglaa Fathy / Shereen Mohammed Al-Shomar / Alhulw H. Alshammari / El-Sayed M. Sherif / Mohamed Ramadan

Sustainability, Vol 15, Iss 2511, p

2023 Volume 2511

Abstract: The application of a higher corrosion resistance coating modified with nano additions can effectively decrease or prevent corrosion from occurring. In the present work, a novel method is successfully developed for the modification of carbon steel ... ...

Abstract	The application of a higher corrosion resistance coating modified with nano additions can effectively decrease or prevent corrosion from occurring. In the present work, a novel method is successfully developed for the modification of carbon steel surfaces aiming for high corrosion resistance using Sn—4% Zn alloy/nanoparticle composite (NiO+ Al 2 O 3 ) coating. Sn—4% Zn alloy/nanoparticle composite (NiO+ Al 2 O 3 ) coatings were deposed on carbon steel using a direct tinning process that involved a power mixture of Sn—4% Zn alloy along with a flux mixture. Regular coating and interface structures were achieved by individual Al 2 O 3 and both NiO and Al 2 O 3 nanoparticle combined additions in the Sn-Zn coating. The maximum coating thickness of 70 ± 1.8 µm was achieved for Al 2 O 3 nanoparticles in the Sn-Zn coating. Interfacial intermetallic layer thickness decreased with all used nanoparticle additions in individual and hybrid conditions. The minimum intermetallic layer thickness of about 2.29 ± 0.28 µm was achieved for Al 2 O 3 nanoparticles in the Sn—Zn coating. Polarization and impedance measurements were used to investigate the influence of the incorporated Al 2 O 3 , NiO, and hybrid Al 2 O 3 /NiO nanoparticles on the passivation of the low-carbon steel (LCS) corrosion and the coated Sn—Zn LCS in sodium chloride solution. It was found that the presence of Al 2 O 3 , NiO, and Al 2 O 3 /NiO nanoparticles remarkably improved the corrosion resistance. The corrosion measurements confirmed that the corrosion resistance of the coated Sn-Zn carbon steel was increased in the presence of these nanoparticles in the following order: Al 2 O 3 /NiO > NiO > Al 2 O 3 .
Keywords	low-carbon steel ; microstructure ; corrosion passivation ; nanoparticles ; Sn-Zn coating ; NiO ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
Subject code	669 ; 290
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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