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  1. Article ; Online: Disseminated intravascular coagulation in perinatal medicine

    M. A. Mingalimov / K. N. Grigorieva / M. V. Tretyakova / I. Elalamy / Kh. G. Sultangadzhieva / V. O. Bitsadze / J. Kh. Khizroeva / A. D. Makatsariya

    Акушерство, гинекология и репродукция, Vol 14, Iss 1, Pp 56-

    2020  Volume 68

    Abstract: Introduction. Disseminated intravascular coagulation (DIC) is an acquired syndrome characterized by intravascular activation of blood clotting without specific localization and arising from various causes. DIC is the most complex and high-priority ... ...

    Abstract Introduction. Disseminated intravascular coagulation (DIC) is an acquired syndrome characterized by intravascular activation of blood clotting without specific localization and arising from various causes. DIC is the most complex and high-priority problem in contemporary clinical medicine including obstetrics and perinatology. DIC significance is related to its peak perinatal mortality, as well as a large rate of complications during childbirth and postpartum period.Aim: to conduct comprehensive data assessment related to DIC pathogenesis and management in pregnant women and newborns.Materials and methods. A search for DIC-related publications within the past 10 years was conducted in international research databases: Scientific Electronic Library Online eLibrary, Google Scholar, ScienceDirect, Cochrane Library, PubMed/Medline. The data regarding DIC diagnostic criteria and markers, as well as current approach to its treatment are presented.Results. DIC may be considered as one of the causes resulting in massive obstetric bleeding. The majority of pregnancy-related complications is manifested as preeclampsia, premature detachment of normally situated placenta and anaphylactoid syndrome of pregnancy. Any massive bleeding should be perceived as hemorrhage resulting from the DIC progression.Conclusion. Knowledge of the DIC pathogenetic mechanisms is necessary for conducting a differential diagnosis and applying timely treatment.
    Keywords disseminated intravascular coagulation ; dic ; perinatal medicine ; thromboses ; hemostatic disorders ; anticoagulant therapy ; gestation ; neonatal thromboses ; Gynecology and obstetrics ; RG1-991
    Subject code 610
    Language Russian
    Publishing date 2020-04-01T00:00:00Z
    Publisher IRBIS LLC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Coronavirus disease (COVID-19) and disseminated intravascular coagulation syndrome

    A. D. Makatsariya / K. N. Grigoreva / M. A. Mingalimov / V. O. Bitsadze / J. Kh. Khizroeva / M. V. Tretyakova / I. Elalamy / A. S. Shkoda / V. B. Nemirovskiy / D. V. Blinov / D. V. Mitryuk

    Акушерство, гинекология и репродукция, Vol 0, Iss

    2020  

    Abstract: COVID-19 is an infectious disease caused by the beta coronavirus SARS-CoV-2, which became widespread worldwide in 2020. In most severe patients, the clinical picture begins with respiratory failure, then progressing to polyorgan failure. The most adverse ...

    Abstract COVID-19 is an infectious disease caused by the beta coronavirus SARS-CoV-2, which became widespread worldwide in 2020. In most severe patients, the clinical picture begins with respiratory failure, then progressing to polyorgan failure. The most adverse prognostic sign is the development of coagulopathy. Based on the analysis of clinical data available to date, 71.4% of those who died and 0.6% of those who survived showed signs of explicit disseminated intravascular coagulation syndrome (DIC-syndrome). Monitoring of D-dimer, prothrombin time (PT), platelet and fibrinogen count are important for determining treatment and indications for hospitalization among patients with COVID-19. If these parameters deteriorate, more "aggressive" intensive care should be performed. Lowmolecular weight heparin (LMWH) should be administered to all patients with diagnosed COVID-19 infection (including non-critical patients) who require hospitalization if these patients have no contraindications for LMWH.
    Keywords sars-cov-2 ; covid-19 ; coronavirus ; disseminated intravascular coagulation syndrome ; dicsyndrome ; anticoagulant therapy ; low molecular weight heparin ; lmwh ; Gynecology and obstetrics ; RG1-991 ; covid19
    Subject code 610
    Language Russian
    Publishing date 2020-04-01T00:00:00Z
    Publisher IRBIS LLC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

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