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Book ; Online: Chapter 4 PREDICTING RESPONSES OF GEO-ECOLOGICALCARBONATE REEF SYSTEMS TO CLIMATE CHANGE:A CONCEPTUAL MODEL AND REVIEW

BROWNE, NICOLA K. / CUTTLER, MICHAEL / MOON, KATIE / MORGAN, KYLE / ROSS, CLAIRE L. / CASTRO-SANGUINO, CAROLINA / KENNEDY, EMMA / HARRIS, DAN / BARNES, PETER / BAUMAN, ANDREW / BEETHAM, EDDIE / BONESSO, JOSHUA / BOZEC, YVES-MARIE / CORNWALL, CHRISTOPHER / DEE, SHANNON / DECARLO, THOMAS / D'OLIVO, JUAN P. / DOROPOULOS, CHRISTOPHER / EVANS, RICHARD D. /

EYRE, BRADLEY / GATENBY, PETER / GONZALEZ, MANUEL / HAMYLTON, SARAH / HANSEN, JEFF / LOWE, RYAN

2021

Keywords	bic Book Industry Communication ; oceanography, climate change, reefs, marine science, marine conservation, marine research
Size	1 electronic resource (143 pages)
Publisher	Taylor and Francis
Document type	Book ; Online
Note	English[eng] ; Open Access
HBZ-ID	HT021291011
ISBN	9780367685225 ; 0367685221
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article ; Online: Liposomal Bupivacaine for Pediatric Celiac Plexus Block: A Case Report of Refractory Constipation Management.

Morgan, Kyle J / Prajapati, Hasmukh J / Frett, Michael J

A&A practice

2021 Volume 15, Issue 8, Page(s) e01518

Abstract: Liposomal bupivacaine is a long-acting amide local anesthetic with a limited list of indications. At the time of publication, use is limited to field block and surgical wound infiltration and, more recently, interscalene nerve block. Although commonly ... ...

Abstract	Liposomal bupivacaine is a long-acting amide local anesthetic with a limited list of indications. At the time of publication, use is limited to field block and surgical wound infiltration and, more recently, interscalene nerve block. Although commonly used in adults, less is known about the safety and efficacy in pediatric patients. We present the use of liposomal bupivacaine for pediatric celiac plexus block in a 12-year-old boy suffering from gastrointestinal complications (eg, pain, constipation, and ileus) after bone marrow transplantation. Celiac plexus block utilizing liposomal bupivacaine was successfully used to palliate his pain and to normalize bowel function.
MeSH term(s)	Anesthetics, Local ; Bupivacaine ; Celiac Plexus ; Child ; Constipation/drug therapy ; Humans ; Male ; Pain, Postoperative
Chemical Substances	Anesthetics, Local ; Bupivacaine (Y8335394RO)
Language	English
Publishing date	2021-08-23
Publishing country	United States
Document type	Case Reports ; Journal Article
ISSN	2575-3126
ISSN (online)	2575-3126
DOI	10.1213/XAA.0000000000001518
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Physics-constrained, low-dimensional models for magnetohydrodynamics: First-principles and data-driven approaches.

Kaptanoglu, Alan A / Morgan, Kyle D / Hansen, Chris J / Brunton, Steven L

Physical review. E

2021 Volume 104, Issue 1-2, Page(s) 15206

Abstract: Plasmas are highly nonlinear and multiscale, motivating a hierarchy of models to understand and describe their behavior. However, there is a scarcity of plasma models of lower fidelity than magnetohydrodynamics (MHD), although these reduced models hold ... ...

Abstract	Plasmas are highly nonlinear and multiscale, motivating a hierarchy of models to understand and describe their behavior. However, there is a scarcity of plasma models of lower fidelity than magnetohydrodynamics (MHD), although these reduced models hold promise for understanding key physical mechanisms, efficient computation, and real-time optimization and control. Galerkin models, obtained by projection of the MHD equations onto a truncated modal basis, and data-driven models, obtained by modern machine learning and system identification, can furnish this gap in the lower levels of the model hierarchy. This work develops a reduced-order modeling framework for compressible plasmas, leveraging decades of progress in projection-based and data-driven modeling of fluids. We begin by formalizing projection-based model reduction for nonlinear MHD systems. To avoid separate modal decompositions for the magnetic, velocity, and pressure fields, we introduce an energy inner product to synthesize all of the fields into a dimensionally consistent, reduced-order basis. Next, we obtain an analytic model by Galerkin projection of the Hall-MHD equations onto these modes. We illustrate how global conservation laws constrain the model parameters, revealing symmetries that can be enforced in data-driven models, directly connecting these models to the underlying physics. We demonstrate the effectiveness of this approach on data from high-fidelity numerical simulations of a three-dimensional spheromak experiment. This manuscript builds a bridge to the extensive Galerkin literature in fluid mechanics and facilitates future principled development of projection-based and data-driven models for plasmas.
Language	English
Publishing date	2021-08-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	2844562-4
ISSN	2470-0053 ; 2470-0045
ISSN (online)	2470-0053
ISSN	2470-0045
DOI	10.1103/PhysRevE.104.015206
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Epidural blood patch for post-dural puncture headaches in adult and paediatric patients with malignancies: a review.

Morgan, Kyle J / Mohan, Rahul / Karol, Seth E / Flerlage, Jamie

British journal of anaesthesia

2021 Volume 126, Issue 6, Page(s) 1200–1207

Abstract: Many anaesthetists are hesitant to perform epidural blood patch in patients with cancer because of the potential risk of seeding the CNS with malignant cells. Recent evidence suggests that anaesthetists may view malignancy as a relative contraindication ... ...

Abstract	Many anaesthetists are hesitant to perform epidural blood patch in patients with cancer because of the potential risk of seeding the CNS with malignant cells. Recent evidence suggests that anaesthetists may view malignancy as a relative contraindication to epidural blood patch rather than an absolute contraindication. This review article summarises the clinical dilemma, reviews the existing literature, and proposes a treatment algorithm that includes the utilisation of for the management of post-dural puncture headache in the oncology population.
MeSH term(s)	Adolescent ; Adult ; Age Factors ; Blood Patch, Epidural/adverse effects ; Child ; Clinical Decision-Making ; Contraindications, Procedure ; Decision Support Techniques ; Female ; Humans ; Male ; Middle Aged ; Neoplasm Seeding ; Neoplasms/complications ; Neoplasms/diagnosis ; Post-Dural Puncture Headache/complications ; Post-Dural Puncture Headache/diagnosis ; Post-Dural Puncture Headache/therapy ; Risk Assessment ; Risk Factors ; Treatment Outcome ; Young Adult
Language	English
Publishing date	2021-02-19
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	80074-0
ISSN	1471-6771 ; 0007-0912
ISSN (online)	1471-6771
ISSN	0007-0912
DOI	10.1016/j.bja.2020.11.041
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Palliative Sedation Therapy Practice Comparison - A Survey of Pediatric Palliative Care and Pain Management Specialists.

Cuviello, Andrea / Ang, Nicholas / Morgan, Kyle / Baker, Justin N / Anghelescu, Doralina L

The American journal of hospice & palliative care

2022 Volume 40, Issue 9, Page(s) 977–986

Abstract: ... ...

Abstract	Context
MeSH term(s)	Humans ; Child ; Palliative Care/methods ; Pain Management ; Hypnotics and Sedatives/therapeutic use ; Benzodiazepines/therapeutic use ; Surveys and Questionnaires
Chemical Substances	Hypnotics and Sedatives ; Benzodiazepines (12794-10-4)
Language	English
Publishing date	2022-12-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	1074344-3
ISSN	1938-2715 ; 1049-9091
ISSN (online)	1938-2715
ISSN	1049-9091
DOI	10.1177/10499091221138298
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Article: Palliative Sedation Therapy in Pediatrics: An Algorithm and Clinical Practice Update.

Cuviello, Andrea / Johnson, Liza-Marie / Morgan, Kyle J / Anghelescu, Doralina L / Baker, Justin N

Children (Basel, Switzerland)

2022 Volume 9, Issue 12

Abstract: Palliative sedation therapy (PST) is an important clinical intervention for pediatric patients with refractory symptoms and suffering during the end-of-life (EOL) period. Variations in PST implementation including medication selection, limited literature ...

Abstract	Palliative sedation therapy (PST) is an important clinical intervention for pediatric patients with refractory symptoms and suffering during the end-of-life (EOL) period. Variations in PST implementation including medication selection, limited literature regarding feasibility in various clinical settings, particularly non-intensive care units, and lack of education on evolving definitions and ideal practices may all contribute to the current underutilization of this valuable resource. We therefore offer a clinical algorithm for identifying appropriate patients for PST, ensuring all other modalities for symptom management have been considered and/or optimized, and present a guideline for PST implementation that can be adapted and individualized based on institutional experience and resource availability. Furthermore, through case-based clinical scenarios, we demonstrate how to incorporate this algorithm into EOL practice.
Language	English
Publishing date	2022-12-01
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2732685-8
ISSN	2227-9067
ISSN	2227-9067
DOI	10.3390/children9121887
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Article ; Online: Low-dose ketamine infusions reduce opioid use in pediatric and young adult oncology patients.

Anghelescu, Doralina L / Ryan, Stephanie / Wu, Diana / Morgan, Kyle J / Patni, Tushar / Li, Yimei

Pediatric blood & cancer

2022 Volume 69, Issue 9, Page(s) e29693

Abstract: Background: Ketamine is an NMDA-receptor antagonist with analgesic and opioid-sparing properties. Although well studied in adults, more robust evidence supporting ketamine's use for pediatric pain management is needed. This retrospective study evaluates ...

Abstract	Background: Ketamine is an NMDA-receptor antagonist with analgesic and opioid-sparing properties. Although well studied in adults, more robust evidence supporting ketamine's use for pediatric pain management is needed. This retrospective study evaluates ketamine's opioid-sparing effectiveness in pediatric and young adult oncology and hematology patients. Procedure: Continuous ketamine infusions administered for pain management between 2010-2020 were reviewed. Data including demographic characteristics, oncology/hematology and pain diagnoses, concurrent pain medications, and ketamine infusions' dose and duration were collected. Opioid consumption data based on delivery via patient-controlled analgesia were collected 1 day before (D1), all days during (cumulatively named D2), and 1 day after (D3) ketamine infusions and calculated as morphine-equivalent doses (mg/kg/day). Data were reported for the entire study group as well as for distinct oncology and end-of-life categories, and short-term acute pain circumstances which included vaso-occlusive crises in hematology patients. Side effects were reviewed. Results: Significantly lower daily opioid consumption was noted in the oncology group, while decreases were not significant in the end-of-life group and in the overall study population. The acute pain group did not show an opioid reduction associated with the ketamine infusions. A largely tolerable side-effect profile was observed, with no differences among each group's incidence. Conclusions: Ketamine infusions were associated with significantly reduced opioid consumption for oncology patients. The opioid-sparing effects of ketamine may vary according to clinical diagnoses and circumstances of use. Overall, low-dose ketamine infusions present an acceptable safety profile in pediatric and young adult patients; nevertheless, individual risks and benefits should be considered.
MeSH term(s)	Acute Pain/drug therapy ; Analgesics/therapeutic use ; Analgesics, Opioid/therapeutic use ; Child ; Death ; Humans ; Infusions, Intravenous ; Ketamine/therapeutic use ; Morphine/therapeutic use ; Neoplasms/complications ; Neoplasms/drug therapy ; Opioid-Related Disorders ; Pain, Postoperative/chemically induced ; Pain, Postoperative/drug therapy ; Retrospective Studies ; Young Adult
Chemical Substances	Analgesics ; Analgesics, Opioid ; Ketamine (690G0D6V8H) ; Morphine (76I7G6D29C)
Language	English
Publishing date	2022-04-04
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
ZDB-ID	2131448-2
ISSN	1545-5017 ; 1545-5009
ISSN (online)	1545-5017
ISSN	1545-5009
DOI	10.1002/pbc.29693
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: A Review of Adult and Pediatric Neuropathic Pain Assessment Tools.

Morgan, Kyle J / Anghelescu, Doralina L

The Clinical journal of pain

2017 Volume 33, Issue 9, Page(s) 844–852

Abstract: Objectives: To identify and summarize the tools currently available for diagnosing and assessing neuropathic pain (NP) in adults and children and to identify areas where further research is required to address deficiencies in the existing tools.: ... ...

Abstract	Objectives: To identify and summarize the tools currently available for diagnosing and assessing neuropathic pain (NP) in adults and children and to identify areas where further research is required to address deficiencies in the existing tools. Methods: A review of journal articles pertaining to the diagnosis and assessment of NP was conducted. Results: We identified 11 tools for assessing NP in adults and 4 for assessing NP in pediatric patients. Conclusions: This article summarizes the various screening and assessment tools available to clinicians for evaluating NP. Despite the availability of the 15 tools discussed, a deficiency remains, particularly in the pediatric realm. To date, there is no well-validated NP assessment tool for children younger than 5 years, no pediatric NP screening tool that has been validated outside the domain of chemotherapy-induced peripheral neuropathy, and no consistent recommendation regarding the optimal tool to use with pediatric patients who have chronic pain. These areas, as well as others, would benefit from further research and development.
Language	English
Publishing date	2017-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	632582-8
ISSN	1536-5409 ; 0749-8047
ISSN (online)	1536-5409
ISSN	0749-8047
DOI	10.1097/AJP.0000000000000476
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Turbid Coral Reefs: Past, Present and Future—A Review

Zweifler (Zvifler), Adi / O’Leary, Michael / Morgan, Kyle / Browne, Nicola K.

Diversity. 2021 June 07, v. 13, no. 6

2021

Abstract: Increasing evidence suggests that coral reefs exposed to elevated turbidity may be more resilient to climate change impacts and serve as an important conservation hotspot. However, logistical difficulties in studying turbid environments have led to poor ... ...

Abstract	Increasing evidence suggests that coral reefs exposed to elevated turbidity may be more resilient to climate change impacts and serve as an important conservation hotspot. However, logistical difficulties in studying turbid environments have led to poor representation of these reef types within the scientific literature, with studies using different methods and definitions to characterize turbid reefs. Here we review the geological origins and growth histories of turbid reefs from the Holocene (past), their current ecological and environmental states (present), and their potential responses and resilience to increasing local and global pressures (future). We classify turbid reefs using new descriptors based on their turbidity regime (persistent, fluctuating, transitional) and sources of sediment input (natural versus anthropogenic). Further, by comparing the composition, function and resilience of two of the most studied turbid reefs, Paluma Shoals Reef Complex, Australia (natural turbidity) and Singapore reefs (anthropogenic turbidity), we found them to be two distinct types of turbid reefs with different conservation status. As the geographic range of turbid reefs is expected to increase due to local and global stressors, improving our understanding of their responses to environmental change will be central to global coral reef conservation efforts.
Keywords	Holocene epoch ; Singapore ; climate change ; conservation status ; coral reefs ; corals ; geographical distribution ; sediments ; turbidity ; Australia
Language	English
Dates of publication	2021-0607
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2518137-3
ISSN	1424-2818
ISSN	1424-2818
DOI	10.3390/d13060251
Database	NAL-Catalogue (AGRICOLA)

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Book ; Online: Importance of tides and winds in influencing the nonstationary behaviour of coastal currents in offshore Singapore

Puah, Jun Yu / Haigh, Ivan D. / Lallemant, David / Morgan, Kyle / Peng, Dongju / Watanabe, Masashi / Switzer, Adam D.

eISSN:

2024

Abstract: Coastal currents significantly impact port activities, coastal landform morphodynamics and ecosystem functioning. It is therefore necessary to understand the physical characteristics and natural variability of these currents within coastal settings. ... ...

Abstract	Coastal currents significantly impact port activities, coastal landform morphodynamics and ecosystem functioning. It is therefore necessary to understand the physical characteristics and natural variability of these currents within coastal settings. Traditional methods such as harmonic analysis assume stationarity of tide-driven currents and thus may not be applicable to systems modulated by variable nontidal inputs and processes. Here we deployed eight tilt current meters at shallow (< 5 m) coral reef environments in southern Singapore. Tilt current meters were positioned around the reefs at the main compass bearings to analyse the spatiotemporal variability of coastal currents in the frequency domain for one year (March 2018 to March 2019). Tidal motions were the primary mechanism of current flow on reefs and account for between 14–45 % of total variance across all sites, with diurnal currents having either similar or greater proportion of energy than semidiurnal currents. In Singapore, the diurnal wind stress, characteristic of the land–sea breeze, strengthens during the monsoons, and its effect on currents was investigated using wavelet coherence. Findings suggest that currents and wind stress were highly correlated at the diurnal and subtidal frequencies during the monsoons with a varying time lag of up to 6 hours with respect to both the phase and the antiphase. We find that wind forcing was responsible for the observed seasonal variations in the diurnal K 1 tidal constituent, its amplitude derived from short-term harmonic analysis. Given the importance of wind, we thus require longer time-series datasets to examine how atmospheric phenomena affect currents at greater time scales to improve predictions.
Subject code	551
Language	English
Publishing date	2024-01-19
Publishing country	de
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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