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  1. Article: [A study on the effect evaluation of virtual reality on workplace employees' emotional optimization].

    Zhang, L F / Liu, X / Ma, J L / Tang, Z C

    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases

    2022  Volume 40, Issue 3, Page(s) 188–191

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Arousal ; Emotions/physiology ; Heart Rate ; Humans ; Virtual Reality ; Workplace
    Language Chinese
    Publishing date 2022-04-18
    Publishing country China
    Document type Journal Article
    ZDB-ID 1050900-8
    ISSN 1001-9391
    ISSN 1001-9391
    DOI 10.3760/cma.j.cn121094-20201210-00681
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [Genetic analysis of a family with hereditary hemorrhagic telangiectasia caused by endoglin gene mutation].

    Ma, J L / Zhou, Z / Li, Y / Zhang, C / Duan, F H / Wang, G M

    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases

    2023  Volume 46, Issue 9, Page(s) 916–920

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Female ; Humans ; Endoglin/genetics ; Hospitals ; Mutation ; Telangiectasia, Hereditary Hemorrhagic ; Pedigree
    Chemical Substances Endoglin
    Language Chinese
    Publishing date 2023-08-21
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 1027965-9
    ISSN 1001-0939
    ISSN 1001-0939
    DOI 10.3760/cma.j.cn112147-20230530-00272
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Construction of molecular subgroups of ulcerative colitis.

    Ma, J-L / Zhang, H-J / Zhang, C-F / Zhang, Y-Y / Wang, G-M

    European review for medical and pharmacological sciences

    2023  Volume 27, Issue 19, Page(s) 9333–9345

    Abstract: Objective: Ulcerative colitis (UC), a chronic inflammatory disease of the colon with unknown etiology, is characterized by remission and recurrence. At present, a considerable number of UC cases are misdiagnosed or delayed in diagnosis and treatment. We ...

    Abstract Objective: Ulcerative colitis (UC), a chronic inflammatory disease of the colon with unknown etiology, is characterized by remission and recurrence. At present, a considerable number of UC cases are misdiagnosed or delayed in diagnosis and treatment. We aimed to identify UC-related genes to aid the development of drugs for this condition.
    Patients and methods: Transcriptome data of 362 patients with UC and 126 control subjects were obtained from the Gene Expression Omnibus. The 362 patients with UC were subgrouped using unsupervised machine learning. R software was used to analyze the clinical characteristics of the subgroups, screen subgroup-specific genes, assess the relationships between gene modules and clinical characteristics using weighted gene co-expression network analysis, and perform Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses of the subgroups.
    Results: Patients with UC were classified into two subgroups. Genes specific to subgroup I included IL21R, ATP8B2, and PLEKHO1. Severe disease tended to be associated with immune cell infiltration; anti-tumor necrosis factor (TNF)-α antibodies and ustekinumab may have been effective in this subgroup. Subgroup II-specific genes included SLC4A4, EPB41L4B, and PLCE1. Patients in this subgroup had mild clinical conditions; however, their disease was more likely to progress to colorectal cancer. Thus, 5-aminosalicylic acid-based drugs may be effective for the treatment of UC in these patients.
    Conclusions: We divided UC into two molecular subgroups based on transcriptome data, providing molecular evidence for the development of diagnostic methods and individualized treatment strategies for UC.
    MeSH term(s) Humans ; Colitis, Ulcerative/diagnosis ; Colitis, Ulcerative/drug therapy ; Colitis, Ulcerative/genetics ; Mesalamine/therapeutic use ; Gene Expression Profiling ; Tumor Necrosis Factor-alpha/genetics ; Intracellular Signaling Peptides and Proteins/genetics
    Chemical Substances Mesalamine (4Q81I59GXC) ; Tumor Necrosis Factor-alpha ; PLEKHO1 protein, human ; Intracellular Signaling Peptides and Proteins
    Language English
    Publishing date 2023-09-29
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 605550-3
    ISSN 2284-0729 ; 1128-3602 ; 0392-291X
    ISSN (online) 2284-0729
    ISSN 1128-3602 ; 0392-291X
    DOI 10.26355/eurrev_202310_33961
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: [Application value of combined deep inhalation and breath-hold technique guided by four-dimensional CT in preoperative localization of solitary pulmonary nodules].

    Xu, Q T / Guo, J X / Jiangping, Ren / Wang, R S / Ma, J L / Zhou, Jianliang

    Zhonghua yi xue za zhi

    2022  Volume 102, Issue 17, Page(s) 1278–1282

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Breath Holding ; Female ; Four-Dimensional Computed Tomography ; Humans ; Indocyanine Green ; Lung Neoplasms/surgery ; Male ; Multiple Pulmonary Nodules/surgery ; Retrospective Studies ; Solitary Pulmonary Nodule ; Thoracic Surgery, Video-Assisted/methods
    Chemical Substances Indocyanine Green (IX6J1063HV)
    Language Chinese
    Publishing date 2022-04-29
    Publishing country China
    Document type Journal Article
    ZDB-ID 132513-9
    ISSN 0376-2491
    ISSN 0376-2491
    DOI 10.3760/cma.j.cn112137-20211116-02558
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: [Arterial spin labeling in assessment of interstitial fibrosis in renal allografts].

    Jiang, B / Wan, J Y / Tian, Y Y / Xu, R / Ma, J L / Li, J / Yu, Y X / Hu, L K / Hu, C H / Zhu, M

    Zhonghua yi xue za zhi

    2024  Volume 104, Issue 4, Page(s) 276–281

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Female ; Male ; Humans ; Adult ; Middle Aged ; Kidney Transplantation ; Cross-Sectional Studies ; Kidney ; Fibrosis ; Allografts
    Language Chinese
    Publishing date 2024-01-05
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 132513-9
    ISSN 0376-2491
    ISSN 0376-2491
    DOI 10.3760/cma.j.cn112137-20230726-00095
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [Influence of UCHL5 on proliferation and apoptosis of SW527 breast cancer cells].

    Ding, F / Ma, J L / Wu, X W / Liu, Z H

    Zhonghua zhong liu za zhi [Chinese journal of oncology

    2019  Volume 40, Issue 12, Page(s) 900–904

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Animals ; Apoptosis/genetics ; Breast Neoplasms/metabolism ; Breast Neoplasms/mortality ; Breast Neoplasms/pathology ; Cell Line, Tumor ; Cell Proliferation/genetics ; Down-Regulation ; Female ; Gene Expression Regulation, Neoplastic ; Heterografts ; Humans ; Kaplan-Meier Estimate ; Mice ; Neoplasm Proteins/metabolism ; Neoplasm Recurrence, Local ; Ubiquitin Thiolesterase/metabolism
    Chemical Substances Neoplasm Proteins ; UCHL5 protein, human (EC 3.4.19.12) ; Ubiquitin Thiolesterase (EC 3.4.19.12)
    Language Chinese
    Publishing date 2019-01-03
    Publishing country China
    Document type Journal Article
    ZDB-ID 603424-x
    ISSN 0253-3766
    ISSN 0253-3766
    DOI 10.3760/cma.j.issn.0253-3766.2018.12.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: [Construction of key question list in the evidence-based guidelines for colorectal cancer screening in China].

    Gao, L / Yu, S Q / Zhou, Q X / Ma, J L / Zhan, S Y / Sun, F

    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi

    2020  Volume 41, Issue 2, Page(s) 267–272

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) China ; Colorectal Neoplasms/diagnosis ; Delphi Technique ; Early Detection of Cancer ; Evidence-Based Practice ; Humans ; Practice Guidelines as Topic
    Language Chinese
    Publishing date 2020-03-12
    Publishing country China
    Document type Journal Article
    ZDB-ID 645026-x
    ISSN 0254-6450
    ISSN 0254-6450
    DOI 10.3760/cma.j.issn.0254-6450.2020.02.022
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    Zs.B 3276: Show issues Location:
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  8. Article: [Significance of Hypoxia-related microRNA for Estimating the Cause of Mechanical Asphyxia Death].

    Zeng, Y / Ma, J L / Chen, L

    Fa yi xue za zhi

    2017  Volume 33, Issue 1, Page(s) 38–41

    Abstract: Under hypoxia condition, microRNA （miRNA） can interact with transcription factors for regulating the cell metabolism, angiogenesis, erythropoiesis, cellular proliferation, differentiation and apoptosis. The biological processes above may play an ... ...

    Abstract Under hypoxia condition, microRNA （miRNA） can interact with transcription factors for regulating the cell metabolism, angiogenesis, erythropoiesis, cellular proliferation, differentiation and apoptosis. The biological processes above may play an important role in mechanical asphyxia death. This article reviews the regulating function of miRNA under hypoxia condition and the influence of hypoxia to biosynthesis of miRNA, which may provide some new ideas to the research of miRNA on determining the cause of mechanical asphyxia death in the field of forensic medicine.
    MeSH term(s) Accidents ; Airway Obstruction/physiopathology ; Apoptosis ; Asphyxia/mortality ; Asphyxia/pathology ; Cause of Death ; Death ; Forensic Medicine ; Humans ; Hypoxia/genetics ; Hypoxia/metabolism ; Hypoxia/physiopathology ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Oxygen
    Chemical Substances MicroRNAs ; Oxygen (S88TT14065)
    Language Chinese
    Publishing date 2017-02
    Publishing country China
    Document type Journal Article ; Review
    ISSN 1004-5619
    ISSN 1004-5619
    DOI 10.3969/j.issn.1004-5619.2017.01.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Effect of anti-mullerian hormone on stem cell factor in serum, follicular fluid and ovarian granular cells of polycystic ovarian syndrome patients.

    Zhang, J-F / Yu, C-M / Yan, L-L / Ma, J-L

    European review for medical and pharmacological sciences

    2018  Volume 22, Issue 22, Page(s) 7877–7882

    Abstract: Objective: Polycystic ovarian syndrome (PCOS) is a common disorder in gynecological practice. Anti-mullerian hormone (AMH) and ovarian granular stem cell factor (SCF) participate in the occurrence and progression of PCOS. This study aimed to investigate ...

    Abstract Objective: Polycystic ovarian syndrome (PCOS) is a common disorder in gynecological practice. Anti-mullerian hormone (AMH) and ovarian granular stem cell factor (SCF) participate in the occurrence and progression of PCOS. This study aimed to investigate the expression of AMH and SCF in PCOS patients and attempt to analyze the effect of AMH on SCF.
    Patients and methods: Both PCOS and non-PCOS patients who received in vitro fertilization (IVF) in our hospital were recruited for measuring AMH and SCF levels in serum, ovarian follicular fluid and granular cells by using enzyme-linked immunosorbent assay (ELISA). Immunohistochemistry (IHC) and Real-time PCR were employed to quantify mRNA and protein levels of SCF in ovarian granular cells after treatment using different dosages of AMH.
    Results: AMH levels in serum, follicular fluid and granular cells in PCOS patients were significantly elevated, whilst SCF level was significantly decreased (p<0.05 in both cases). Therefore, there was a negative correlation between AMH and SCF level (p<0.05). In 5 ng/ml, 10 ng/ml and 15 ng/ml group, SCF protein positive rate was gradually decreased and was significantly lower compared to that of blank control (p<0.05). After treatment using AMH for 12, 24 and 48 h, SCF mRNA expression in the granular cell was significantly decreased (p<0.05). With higher dosage, SCF mRNA was gradually down-regulated in granular cells (p<0.05).
    Conclusions: High level of AMH and low level of SCF existed in serum, follicular fluid, and granular cells in PCOS patients. AMH exhibited negative regulatory effects on SCF.
    MeSH term(s) Adult ; Anti-Mullerian Hormone/blood ; Anti-Mullerian Hormone/metabolism ; Anti-Mullerian Hormone/pharmacology ; Case-Control Studies ; Dose-Response Relationship, Drug ; Down-Regulation ; Female ; Follicle Stimulating Hormone/blood ; Follicular Fluid/metabolism ; Granulosa Cells/metabolism ; Humans ; Luteinizing Hormone/blood ; Polycystic Ovary Syndrome/blood ; Polycystic Ovary Syndrome/metabolism ; Stem Cell Factor/blood ; Stem Cell Factor/metabolism
    Chemical Substances Stem Cell Factor ; Anti-Mullerian Hormone (80497-65-0) ; Luteinizing Hormone (9002-67-9) ; Follicle Stimulating Hormone (9002-68-0)
    Language English
    Publishing date 2018-12-11
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 605550-3
    ISSN 2284-0729 ; 1128-3602 ; 0392-291X
    ISSN (online) 2284-0729
    ISSN 1128-3602 ; 0392-291X
    DOI 10.26355/eurrev_201811_16413
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    Zs.A 1887: Show issues Location:
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  10. Article: [Research Progress on Estimation of Early Postmortem Interval].

    Tao, L / Ma, J L / Chen, L

    Fa yi xue za zhi

    2016  Volume 32, Issue 6, Page(s) 444–447

    Abstract: Estimation of postmortem interval （PMI） is very important for judging the nature of cases, restricting the scope of investigation and suspect, which is always the emphasis and difficulty for forensic pathology. Early postmortem interval is the time ... ...

    Abstract Estimation of postmortem interval （PMI） is very important for judging the nature of cases, restricting the scope of investigation and suspect, which is always the emphasis and difficulty for forensic pathology. Early postmortem interval is the time between 0 and 24 hours after death. Due to the shorter time after the case occurred, precisely estimating early postmortem interval can help solve crimes, which has important significance in forensic medicine. In recent years, series of advanced methods and technologies are used to estimate the early PMI by the internal and overseas scholars who work in the forensic area. This paper reviews the research progress on fluids biochemistry, supravital reactions, metabolomics, imageology and the degradation rule of genetic material to provide a new idea to the study and application for estimation of early PMI.
    MeSH term(s) Autopsy ; Forensic Medicine ; Forensic Pathology ; Humans ; Postmortem Changes ; Time Factors
    Language Chinese
    Publishing date 2016-12
    Publishing country China
    Document type Journal Article ; Review
    ISSN 1004-5619
    ISSN 1004-5619
    DOI 10.3969/j.issn.1004-5619.2016.06.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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