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  1. Article ; Online: Realization of Supersymmetry and Its Spontaneous Breaking in Quantum Hall Edges.

    Ma, Ken K W / Wang, Ruojun / Yang, Kun

    Physical review letters

    2021  Volume 126, Issue 20, Page(s) 206801

    Abstract: Supersymmetry (SUSY) relating bosons and fermions plays an important role in unifying different fundamental interactions in particle physics. Since no superpartners of elementary particles have been observed, SUSY, if present, must be broken at low- ... ...

    Abstract Supersymmetry (SUSY) relating bosons and fermions plays an important role in unifying different fundamental interactions in particle physics. Since no superpartners of elementary particles have been observed, SUSY, if present, must be broken at low-energy. This makes it important to understand how SUSY is realized and broken, and study their consequences. We show that an N=(1,0) SUSY, arguably the simplest type, can be realized at the edge of the Moore-Read quantum Hall state. Depending on the absence or presence of edge reconstruction, both SUSY-preserving and SUSY broken phases can be realized in the same system, allowing for their unified description. The significance of the gapless fermionic Goldstino mode in the SUSY broken phase is discussed.
    Language English
    Publishing date 2021-06-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.126.206801
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Thermal Equilibration on the Edges of Topological Liquids.

    Ma, Ken K W / Feldman, D E

    Physical review letters

    2020  Volume 125, Issue 1, Page(s) 16801

    Abstract: Thermal conductance has emerged as a powerful probe of topological order in the quantum Hall effect and beyond. The interpretation of experiments crucially depends on the ratio of the sample size and the equilibration length, on which energy exchange ... ...

    Abstract Thermal conductance has emerged as a powerful probe of topological order in the quantum Hall effect and beyond. The interpretation of experiments crucially depends on the ratio of the sample size and the equilibration length, on which energy exchange among contrapropagating chiral modes becomes significant. We show that at low temperatures the equilibration length diverges as 1/T^{2} for almost all Abelian and non-Abelian topological orders. A faster 1/T^{4} divergence is present on the edges of the non-Abelian PH-Pfaffian and negative-flux Read-Rezayi liquids. We address experimental consequences of the 1/T^{2} and 1/T^{4} laws in a sample, shorter than the equilibration length.
    Language English
    Publishing date 2020-07-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.125.016801
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Methicillin-sensitive Staphylococcus aureus chorioamnionitis and foetal death after mechanical induction of labour: a case report.

    Iruloh, Chibuike Godson / Bonner, Samantha / Ma, Ken

    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology

    2017  Volume 38, Issue 2, Page(s) 285–286

    MeSH term(s) Adult ; Catheterization/adverse effects ; Catheterization/methods ; Chorioamnionitis/microbiology ; Female ; Fetal Death/etiology ; Fetal Diseases/microbiology ; Gestational Age ; Humans ; Labor, Induced/adverse effects ; Lung/embryology ; Lung/microbiology ; Methicillin ; Pakistan/ethnology ; Pregnancy ; Staphylococcal Infections/complications ; Staphylococcal Infections/microbiology ; Staphylococcus aureus/drug effects ; Staphylococcus aureus/isolation & purification ; United Kingdom
    Chemical Substances Methicillin (Q91FH1328A)
    Language English
    Publishing date 2017-09-13
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 604639-3
    ISSN 1364-6893 ; 0144-3615
    ISSN (online) 1364-6893
    ISSN 0144-3615
    DOI 10.1080/01443615.2017.1343809
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A Prospective Study to Identify Rates of SARS-CoV-2 Virus in the Peritoneum and Lower Genital Tract of Patients Having Surgery: An Observational Study.

    Jones, Dominique / Faluyi, David / Hamilton, Sarah / Stylianides, Nicholas / Ma, Ken / Duff, Sarah / Machin, Nicholas / Edmondson, Richard J

    Journal of minimally invasive gynecology

    2021  Volume 28, Issue 9, Page(s) 1633–1636

    Abstract: Study objective: The risks to surgeons of carrying out aerosol-generating procedures during the coronavirus disease 2019 (COVID-19) pandemic are unknown. To start to define these risks, in a systematic manner, we investigated the presence of severe ... ...

    Abstract Study objective: The risks to surgeons of carrying out aerosol-generating procedures during the coronavirus disease 2019 (COVID-19) pandemic are unknown. To start to define these risks, in a systematic manner, we investigated the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus in the abdominal fluid and lower genital tract of patients undergoing surgery.
    Design: Prospective cross-sectional observational study.
    Setting: Single, large United Kingdom hospital.
    Patients: Total of 113 patients undergoing abdominal surgery or instrumentation of the lower genital tract.
    Interventions: We took COVID-19 swabs from the peritoneal cavity and from the vagina from all eligible patients. Results were stratified by preoperative COVID-19 status.
    Measurements and main results: In patients who were presumed COVID-19 negative at the time of surgery, SARS-CoV-2 virus RNA was detected in 0 of 102 peritoneal samples and 0 of 98 vaginal samples. Both cohorts included 4 patients who were antibody positive but nasopharyngeal swab test negative at the time of surgery. Peritoneal and vaginal swabs were also negative in 1 patient who had a positive nasopharyngeal swab immediately before surgery.
    Conclusion: The presence of SARS-CoV-2 RNA in the abdominal fluid or lower genital tract of presumed negative patients is nil or extremely low. These data will inform surgeons of the risks of restarting laparoscopic surgery at a time when COVID-19 is endemic in the population.
    MeSH term(s) COVID-19 ; Cross-Sectional Studies ; Female ; Humans ; Peritoneum ; Prospective Studies ; RNA, Viral ; SARS-CoV-2 ; Vagina
    Chemical Substances RNA, Viral
    Language English
    Publishing date 2021-02-11
    Publishing country United States
    Document type Journal Article ; Observational Study
    ZDB-ID 2186934-0
    ISSN 1553-4669 ; 1553-4650
    ISSN (online) 1553-4669
    ISSN 1553-4650
    DOI 10.1016/j.jmig.2021.02.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Differential contribution of inhibitory phosphorylation of CDC2 and CDK2 for unperturbed cell cycle control and DNA integrity checkpoints.

    Chow, Jeremy P H / Siu, Wai Yi / Ho, Horace T B / Ma, Ken Hoi Tang / Ho, Chui Chui / Poon, Randy Y C

    The Journal of biological chemistry

    2003  Volume 278, Issue 42, Page(s) 40815–40828

    Abstract: Inhibition of cyclin-dependent kinases (CDKs) by Thr14/Tyr15 phosphorylation is critical for normal cell cycle progression and is a converging event for several cell cycle checkpoints. In this study, we compared the relative contribution of inhibitory ... ...

    Abstract Inhibition of cyclin-dependent kinases (CDKs) by Thr14/Tyr15 phosphorylation is critical for normal cell cycle progression and is a converging event for several cell cycle checkpoints. In this study, we compared the relative contribution of inhibitory phosphorylation for cyclin A/B1-CDC2 and cyclin A/E-CDK2 complexes. We found that inhibitory phosphorylation plays a major role in the regulation of CDC2 but only a minor role for CDK2 during the unperturbed cell cycle of HeLa cells. The relative importance of inhibitory phosphorylation of CDC2 and CDK2 may reflect their distinct cellular functions. Despite this, expression of nonphosphorylation mutants of both CDC2 and CDK2 triggered unscheduled histone H3 phosphorylation early in the cell cycle and was cytotoxic. DNA damage by a radiomimetic drug or replication block by hydroxyurea stimulated a buildup of cyclin B1 but was accompanied by an increase of inhibitory phosphorylation of CDC2. After DNA damage and replication block, all cyclin-CDK pairs that control S phase and mitosis were to different degrees inhibited by phosphorylation. Ectopic expression of nonphosphorylated CDC2 stimulated DNA replication, histone H3 phosphorylation, and cell division even after DNA damage. Similarly, a nonphosphorylation mutant of CDK2, but not CDK4, disrupted the G2 DNA damage checkpoint. Finally, CDC25A, CDC25B, a dominant-negative CHK1, but not CDC25C or a dominant-negative WEE1, stimulated histone H3 phosphorylation after DNA damage. These data suggest differential contributions for the various regulators of Thr14/Tyr15 phosphorylation in normal cell cycle and during the DNA damage checkpoint.
    MeSH term(s) Bromodeoxyuridine/pharmacology ; CDC2 Protein Kinase/metabolism ; CDC2-CDC28 Kinases/metabolism ; Cell Cycle ; Cell Cycle Proteins ; Coloring Agents/pharmacology ; Cyclin-Dependent Kinase 2 ; DNA/chemistry ; DNA/metabolism ; DNA Damage ; Flow Cytometry ; Genes, Dominant ; HeLa Cells ; Histones/metabolism ; Humans ; Hydroxyurea/pharmacology ; Mitosis ; Mutation ; Nuclear Proteins ; Phosphorylation ; Protein-Tyrosine Kinases/metabolism ; Thymidine/metabolism ; Time Factors
    Chemical Substances Cell Cycle Proteins ; Coloring Agents ; Histones ; Nuclear Proteins ; DNA (9007-49-2) ; Protein-Tyrosine Kinases (EC 2.7.10.1) ; WEE1 protein, human (EC 2.7.10.2) ; CDC2 Protein Kinase (EC 2.7.11.22) ; CDC2-CDC28 Kinases (EC 2.7.11.22) ; CDK2 protein, human (EC 2.7.11.22) ; Cyclin-Dependent Kinase 2 (EC 2.7.11.22) ; Bromodeoxyuridine (G34N38R2N1) ; Thymidine (VC2W18DGKR) ; Hydroxyurea (X6Q56QN5QC)
    Language English
    Publishing date 2003-08-11
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2997-x
    ISSN 1083-351X ; 0021-9258
    ISSN (online) 1083-351X
    ISSN 0021-9258
    DOI 10.1074/jbc.M306683200
    Database MEDical Literature Analysis and Retrieval System OnLINE

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