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  1. AU="Ma, Penglei"
  2. AU="Monteleone, Pedro Augusto Araújo"
  3. AU="Sakuma, Ikki"
  4. AU="Cherniack, Andrew D."
  5. AU="Beitollahi, Hadi"
  6. AU="Hai-Tao Tang"
  7. AU=Rouse Benjamin AU=Rouse Benjamin
  8. AU="Rabensteiner, Toni"
  9. AU="Chowdhury, Forhad Uddin Hassan" AU="Chowdhury, Forhad Uddin Hassan"
  10. AU=Verdone Loredana AU=Verdone Loredana
  11. AU="Venegas, M"
  12. AU="Burtnick, Mary N"
  13. AU=Frisoni Giovanni B
  14. AU="Dhiraj Kumar"
  15. AU="Isaac S. Lee"
  16. AU="Bals, Julia"
  17. AU="Rovira-Clavé, Xavier"
  18. AU="Den Boer, Monique L"
  19. AU="Potts, T."
  20. AU="Cifuentes-Diaz, Carmen"
  21. AU="Alvim, Ricardo G"
  22. AU="Barron II, Joseph C"
  23. AU="Godin, Shea-Lee"
  24. AU="Leng, Chengcai"
  25. AU="Hyslop, Brian W"
  26. AU="Suzanne Fischer"
  27. AU="Aboelata, Noha"
  28. AU="Chiang, Sarah N"
  29. AU="Wessel, Kristin M"
  30. AU="Wilson, Jenna M"
  31. AU="Goines, Paula"
  32. AU=Ippolito Mariachiara AU=Ippolito Mariachiara
  33. AU="Jose Chauca"
  34. AU="Asih, Puji B S"
  35. AU="Dsane-Selby, Lydia"
  36. AU="Tolossa, Tadesse"
  37. AU="Erdal Bedir"

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  1. Artikel ; Online: Exosomal miR-331-3p derived from chemoresistant osteosarcoma cells induces chemoresistance through autophagy.

    Meng, Chenyang / Yang, Yun / Feng, Wei / Ma, Penglei / Bai, Rui

    Journal of orthopaedic surgery and research

    2023  Band 18, Heft 1, Seite(n) 892

    Abstract: Background: Osteosarcoma is a common malignant bone tumor, and chemotherapy can effectively improve the prognosis. MicroRNA-331 (MiR-331) is associated with poor cancer outcomes. However, the role of miR-331 in osteosarcoma remains to be explored.: ... ...

    Abstract Background: Osteosarcoma is a common malignant bone tumor, and chemotherapy can effectively improve the prognosis. MicroRNA-331 (MiR-331) is associated with poor cancer outcomes. However, the role of miR-331 in osteosarcoma remains to be explored.
    Methods: Drug-resistant osteosarcoma cells were cultured, and their exosomes were purified. The secretion and uptake of exosomes by drug-resistant osteosarcoma and osteosarcoma cells were confirmed using a fluorescence tracking assay and Transwell experiments. The effects of drug-resistant exosomes on cell proliferation were determined using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. siRNA-Drosha and neutral sphingomyelinase inhibitor GW4869 were used to determine the transfer of miRNAs. qRT-PCR and western blotting were used to detect the role of autophagy in the regulation of drug-resistant cell-derived exosomal miR-331-3p.
    Results: Exosomal miR-331-3p levels in drug-resistant cells were higher than in exosomes from osteosarcoma cells. The exosomes secreted by the drug-resistant osteosarcoma cells could be absorbed by osteosarcoma cells, leading to acquired drug resistance in previously non-resistance cells. Inhibition of miRNAs resulted in reduced transmission of drug resistance transmission by exosomes. Exosomes from drug-resistant osteosarcoma cells transfected with siRNA-Drosha or treated by GW4869 could not enhance the proliferation of MG63 and HOS cells. Finally, miR-331-3p in the exosomes secreted by drug-resistant osteosarcoma cells could induce autophagy of osteosarcoma cells, allowing them to acquire drug resistance. The inhibition of miR-331-3p decreased drug resistance of osteosarcoma cells.
    Conclusion: Exosomes secreted from chemoresistant osteosarcoma cells promote drug resistance through miR-331-3p and autophagy. Inhibition of miR-331-3p could be used to alleviate drug resistance in osteosarcoma.
    Mesh-Begriff(e) Humans ; Drug Resistance, Neoplasm/genetics ; MicroRNAs/genetics ; Osteosarcoma/drug therapy ; Osteosarcoma/genetics ; RNA, Small Interfering ; Bone Neoplasms/drug therapy ; Bone Neoplasms/genetics ; Autophagy/genetics ; Cell Proliferation/genetics ; Cell Line, Tumor
    Chemische Substanzen MicroRNAs ; RNA, Small Interfering ; MIRN331 microRNA, human
    Sprache Englisch
    Erscheinungsdatum 2023-11-22
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2252548-8
    ISSN 1749-799X ; 1749-799X
    ISSN (online) 1749-799X
    ISSN 1749-799X
    DOI 10.1186/s13018-023-04338-8
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  2. Artikel ; Online: Rac2 enhances activation of microglia and astrocytes, inflammatory response, and apoptosis via activating JNK signaling pathway and suppressing SIRT1 expression in chronic constriction injury-induced neuropathic pain.

    An, Min / Qiu, Yi / Wang, Caixia / Ma, Penglei / Ding, Yumei

    Journal of neuropathology and experimental neurology

    2023  Band 82, Heft 5, Seite(n) 419–426

    Abstract: Neuropathic pain (NP) is pain caused by injury or dysfunction of the somatosensory system. The role of Rac2, a member of the Rac family, which is expressed in neutrophils, macrophages, and adult T cells, in NP remains unclear. Using a chronic ... ...

    Abstract Neuropathic pain (NP) is pain caused by injury or dysfunction of the somatosensory system. The role of Rac2, a member of the Rac family, which is expressed in neutrophils, macrophages, and adult T cells, in NP remains unclear. Using a chronic constriction injury (CCI)-induced NP model in rats, we found that Rac2 expression was elevated in rats with CCI-induced NP and that overexpression of Rac2 aggravated the NP. Rac2 overexpression also aggravated the inflammatory response, induced activation of microglia and astrocytes, and enhanced apoptosis whereas knockdown of Rac2 had the opposite effects. Rac2 suppressed SIRT1 expression via activating the c-Jun N-terminal kinase (JNK) signaling pathway. In rescue experiments, SRT1720, an activator of SIRT1, reversed the effect of Rac2 on glial activation, inflammatory response, and apoptosis. These findings indicate that Rac2 enhances the activation of microglia and astrocytes, inflammatory response, and apoptosis via activating the JNK signaling pathway and suppressing SIRT1 expression in CCI-induced NP.
    Mesh-Begriff(e) Rats ; Animals ; Microglia/metabolism ; Astrocytes/metabolism ; Rats, Sprague-Dawley ; MAP Kinase Signaling System ; Sirtuin 1/genetics ; Sirtuin 1/metabolism ; Sirtuin 1/pharmacology ; Constriction ; Neuralgia/etiology ; Neuralgia/metabolism
    Chemische Substanzen Sirtuin 1 (EC 3.5.1.-) ; Sirt1 protein, rat (EC 3.5.1.-)
    Sprache Englisch
    Erscheinungsdatum 2023-02-12
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 3088-0
    ISSN 1554-6578 ; 0022-3069
    ISSN (online) 1554-6578
    ISSN 0022-3069
    DOI 10.1093/jnen/nlad006
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  3. Artikel: Behaviors of two semi-passive oscillating hydrofoils with a tandem configuration

    Ma, Penglei / Wang, Yong / Xie, Yudong / Liu, Guijie

    Energy. 2021 Jan. 01, v. 214

    2021  

    Abstract: Two hydrofoils with a tandem spatial configuration can share the same flow window. The wake vortex interaction and blockage effect have noticeable impacts on the response of two hydrofoils for a semi-passive system. In this study, the responses of two ... ...

    Abstract Two hydrofoils with a tandem spatial configuration can share the same flow window. The wake vortex interaction and blockage effect have noticeable impacts on the response of two hydrofoils for a semi-passive system. In this study, the responses of two oscillating hydrofoils with a tandem arrangement are examined using a numerical approach. The results indicate that the downstream hydrofoil has an inferior energy harvesting performance because it operates in the upstream hydrofoil wake. Several special cases were observed. As a result of a negative interaction in the wake vortices, (i) two hydrofoils were shown to have different heaving equilibrium positions and thus no longer share the flow window; and (ii) the downstream hydrofoil was demonstrated to have a larger heaving amplitude but a lower energy harvesting performance. At a very high oscillation frequency, the downstream hydrofoil tends to incur an irregular response owing to the intense vortex formation and shedding, as well as a constant interaction of the wake vortices. The downstream hydrofoil achieves an unexpectedly better energy harvesting performance due to a favorable interaction of the wake vortices. However, the entire system can’t achieve high efficiency due to the poor energy harvesting performance of the upstream hydrofoil. When two semi-passive oscillating hydrofoils have a tandem configuration, negative wake vortex interactions should be avoided instead of seeking a favorable interaction.
    Schlagwörter behavior ; energy ; energy poverty ; sheds ; windows
    Sprache Englisch
    Erscheinungsverlauf 2021-0101
    Erscheinungsort Elsevier Ltd
    Dokumenttyp Artikel
    ZDB-ID 2019804-8
    ISSN 0360-5442 ; 0360-5442
    ISSN (online) 0360-5442
    ISSN 0360-5442
    DOI 10.1016/j.energy.2020.118908
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  4. Artikel ; Online: Exosomal miR-429 derived from adipose-derived stem cells ameliorated chondral injury in osteoarthritis via autophagy by targeting FEZ2.

    Meng, Chenyang / Na, Yuyan / Han, Changxu / Ren, Yizhong / Liu, Ming / Ma, Penglei / Bai, Rui

    International immunopharmacology

    2023  Band 120, Seite(n) 110315

    Abstract: Background: Osteoarthritis (OA) is the most prevalent musculoskeletal disease, imposing a significant public health burden. Exosomes might be an effective means of treating OA.: Purpose: To investigate the role of exosomes from adipose tissue-derived ...

    Abstract Background: Osteoarthritis (OA) is the most prevalent musculoskeletal disease, imposing a significant public health burden. Exosomes might be an effective means of treating OA.
    Purpose: To investigate the role of exosomes from adipose tissue-derived stromal cells (ADSCs) in OA. We explored whether exosomes from ADSCs could be absorbed by OA chondrocytes, whether there were differences in miR-429 expression in the exosomes of ADSCs and chondrocytes, and whether ADSC exosomal miR-429 could enhance chondrocyte proliferation to exert therapeutic effects in OA.
    Study design: Controlled laboratory study.
    Methods: ADSCs were isolated and cultured from 4-week-old Sprague-Dawley rats. ADSCs and chondrocytes were identified by flow cytometry assay and fluorescent staining, respectively. The exosomes were extracted and identified. Exosome transport was verified by cell staining and co-culture. Beclin 1, collagen II, LC3-II/I, miR-429, and FEZ2 mRNA and protein expression were investigated with real-time PCR and western blotting, respectively. Chondrocyte proliferation was investigated with Cell Counting Kit-8 (CCK-8) assay. The association between miR-429 and FEZ2 was verified with luciferase assay. A rat OA model was established and rat knee joint cartilage tissue was examined with hematoxylin-eosin and toluidine blue staining.
    Results: Both ADSCs and chondrocytes secreted exosomes and ADSC-derived exosomes could be absorbed by the chondrocytes. ADCS exosomes contained higher miR-429 levels than chondrocyte exosomes. The luciferase assay demonstrated that miR-429 directly targeted FEZ2. Compared with the OA group, miR-429 promoted chondrocyte proliferation while FEZ2 decreased it. miR-429 promoted autophagy by targeting FEZ2 to ameliorate cartilage injury. In vivo, miR-429 promoted autophagy to alleviate OA by targeting FEZ2.
    Conclusion: ADSC exosomes could be beneficial for OA and could be absorbed by chondrocytes to promote chondrocyte proliferation through miR-429. miR-429 ameliorated cartilage injury in OA by targeting FEZ2 and promoting autophagy.
    Mesh-Begriff(e) Rats ; Animals ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Cells, Cultured ; Rats, Sprague-Dawley ; Chondrocytes/metabolism ; Osteoarthritis/metabolism ; Autophagy/genetics ; Stem Cells/metabolism
    Chemische Substanzen MicroRNAs
    Sprache Englisch
    Erscheinungsdatum 2023-05-27
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 2043785-7
    ISSN 1878-1705 ; 1567-5769
    ISSN (online) 1878-1705
    ISSN 1567-5769
    DOI 10.1016/j.intimp.2023.110315
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  5. Artikel: Numerical analysis of a tidal current generator with dual flapping wings

    Ma, Penglei / Wang, Yong / Xie, Yudong / Huo, Zhipu

    Energy. 2018 July 15, v. 155

    2018  

    Abstract: Flapping wings, inspired by the mechanism of birds and fish, can act as generators to harvest energy from tidal currents. The hydraulic system is simplified as a spring-damper system to establish the coupling equations relating to the wing motion and the ...

    Abstract Flapping wings, inspired by the mechanism of birds and fish, can act as generators to harvest energy from tidal currents. The hydraulic system is simplified as a spring-damper system to establish the coupling equations relating to the wing motion and the hydrodynamic forces. To provide guidance for design of a fully flow-induced flapping wings energy harvesting system, the behaviors of both system response and energy extraction performance are analyzed using two-dimensional numerical approach. Depending on the rotary actuator radius R, and the volume ratio β between the cylinder and rotary actuator, three distinguishable behaviors are observed in the system response and energy extraction performance. At larger R and smaller β, the dual wings tend to undergo a damped reduction flapping motion because the pitching motion consumes a significant amount of energy. Both decreasing R and increasing β can reduce the energy consumption of the pitching motion, and thus allow the dual wings to achieve a sustainable flapping motion. Although an irregular response can achieve a self-sustained flapping motion, it is unfavorable owing to its unstable power output. The regular response essential for stable energy harvesting is realized over a range of coupling parameters. The energy extraction performance of the system is closely associated with β but also slightly depends on R.
    Schlagwörter birds ; energy ; equations ; fish ; hydrodynamics ; tides
    Sprache Englisch
    Erscheinungsverlauf 2018-0715
    Umfang p. 1077-1089.
    Erscheinungsort Elsevier Ltd
    Dokumenttyp Artikel
    ZDB-ID 2019804-8
    ISSN 0360-5442 ; 0360-5442
    ISSN (online) 0360-5442
    ISSN 0360-5442
    DOI 10.1016/j.energy.2018.05.035
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  6. Artikel: Analysis of a hydraulic coupling system for dual oscillating foils with a parallel configuration

    Ma, Penglei / Jianhua Zhang / Yong Wang / Yudong Xie

    Energy. 2018 Jan. 15, v. 143

    2018  

    Abstract: The generators using oscillating foil to extract tidal energy have obvious advantages in shallow water. To get rid of the complicated control system, we proposed a hydraulic system to couple dual foils and realize the self-sustained oscillation motion of ...

    Abstract The generators using oscillating foil to extract tidal energy have obvious advantages in shallow water. To get rid of the complicated control system, we proposed a hydraulic system to couple dual foils and realize the self-sustained oscillation motion of the foil. The coupling equations related to the foils' motion and hydrodynamic are established. Computations are performed using the software Fluent with a NACA0015 foil. A User Defined Function is compiled for iteration. The classical Runge-Kutta method is employed to compute the displacement and moving velocity. Computation results demonstrate that the hydraulic coupling system realizes well the self-sustained oscillation motion of foil instead of external control. The response of the coupling system is independent of the initial pitching angle. The damping coefficients have a significant effect on the response of coupling system. The response of coupling system, oscillation amplitude and frequency, declines with the increasing of damping coefficient, especially at relatively low damping coefficient. The energy consumption of pitching motion most appears in the stage of angle decrease. The evolutions of time-averaged power coefficient and energy harvesting efficiency versus damping coefficient are quite similar to that of the oscillation amplitude and frequency.
    Schlagwörter computer software ; energy ; equations ; hydrodynamics ; water power
    Sprache Englisch
    Erscheinungsverlauf 2018-0115
    Umfang p. 273-283.
    Erscheinungsort Elsevier Ltd
    Dokumenttyp Artikel
    ZDB-ID 2019804-8
    ISSN 0360-5442 ; 0360-5442
    ISSN (online) 0360-5442
    ISSN 0360-5442
    DOI 10.1016/j.energy.2017.10.141
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  7. Artikel ; Online: The Protective Effect of Sulodexide on Acute Lung Injury Induced by a Murine Model of Obstructive Jaundice.

    Ma, Penglei / Long, Yue / Fu, Qiang / Liu, Yanhong / Yang, Yitian / Zhao, Weixing / Liu, Qiangwei / Li, Yang / Mi, Weidong

    Publikation ZURÜCKGEZOGEN

    BioMed research international

    2022  Band 2022, Seite(n) 8717950

    Abstract: Introduction: The effect of sulodexide (SLX) on obstructive jaundice- (OJ-) induced acute lung injury (ALI) in rats was examined in this study.: Methods: In this study, 48 rats were randomly assigned to one of six groups: sham, OJ, OJ+saline, OJ+SLX ( ...

    Abstract Introduction: The effect of sulodexide (SLX) on obstructive jaundice- (OJ-) induced acute lung injury (ALI) in rats was examined in this study.
    Methods: In this study, 48 rats were randomly assigned to one of six groups: sham, OJ, OJ+saline, OJ+SLX (0.5 mg/ml/d), OJ+SLX (1 mg/ml/d), and OJ+SLX (2 mg/ml/d). The pathological lung injury was assessed by histological analysis and lung injury grading. ELISA kits were used to evaluate the expression of IL-6, IL-1, TNF-
    Results: The OJ-induced ALI rats showed severe lung injury. The value of IL-6, IL-1
    Conclusion: The results suggested that SLX attenuates OJ-induced ALI in rats by protecting the pulmonary microvascular endothelial barrier.
    Mesh-Begriff(e) Acute Lung Injury/drug therapy ; Acute Lung Injury/etiology ; Animals ; Antioxidants ; Cadherins ; Claudin-5 ; Disease Models, Animal ; Evans Blue/adverse effects ; Glycosaminoglycans/pharmacology ; Interleukin-6 ; Jaundice, Obstructive/complications ; Rats ; Tumor Necrosis Factor-alpha
    Chemische Substanzen Antioxidants ; Cadherins ; Claudin-5 ; Glycosaminoglycans ; Interleukin-6 ; Tumor Necrosis Factor-alpha ; Evans Blue (45PG892GO1) ; glucuronyl glucosamine glycan sulfate (75HGV0062C)
    Sprache Englisch
    Erscheinungsdatum 2022-08-26
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Retracted Publication
    ZDB-ID 2698540-8
    ISSN 2314-6141 ; 2314-6133
    ISSN (online) 2314-6141
    ISSN 2314-6133
    DOI 10.1155/2022/8717950
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  8. Artikel ; Online: Magnetic-acoustic actuated spinous microrobot for enhanced degradation of organic pollutants.

    Yu, Shimin / Liu, Chenlu / Sui, Mingyang / Wei, Haiqiang / Cheng, Haoyuan / Chen, Yujing / Zhu, Yanhe / Wang, Haocheng / Ma, Penglei / Wang, Lin / Li, Tianlong

    Ultrasonics sonochemistry

    2023  Band 102, Seite(n) 106714

    Abstract: A growing interest in the development of efficient strategies for the removal of organic pollutants from polluted water is emerging. As such, artificial micro/nano machines performing excellent water purification tasks have recently attracted more ... ...

    Abstract A growing interest in the development of efficient strategies for the removal of organic pollutants from polluted water is emerging. As such, artificial micro/nano machines performing excellent water purification tasks have recently attracted more research attention of scientists. Hereby a spinous Fe
    Sprache Englisch
    Erscheinungsdatum 2023-12-14
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 1208333-1
    ISSN 1873-2828 ; 1350-4177
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    ISSN 1350-4177
    DOI 10.1016/j.ultsonch.2023.106714
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  9. Artikel ; Online: Ketamine relieves depression-like behaviors induced by chronic postsurgical pain in rats through anti-inflammatory, anti-oxidant effects and regulating BDNF expression.

    Yang, Yitian / Song, Yuxiang / Zhang, Xuan / Zhao, Weixing / Ma, Tao / Liu, Yi / Ma, Penglei / Zhao, Yifan / Zhang, Hong

    Psychopharmacology

    2020  Band 237, Heft 6, Seite(n) 1657–1669

    Abstract: Rationale: Clinically, chronic postsurgical pain (CPSP) is very common. Many CPSP patients may experience depression. Thus far, little is known about the mechanism of the comorbidity of CPSP and depression. Ketamine has been confirmed to possess ... ...

    Abstract Rationale: Clinically, chronic postsurgical pain (CPSP) is very common. Many CPSP patients may experience depression. Thus far, little is known about the mechanism of the comorbidity of CPSP and depression. Ketamine has been confirmed to possess analgesic and rapid antidepressant effects, but it is unclear whether ketamine can relieve the comorbidity of CPSP and depression.
    Objectives: The present study evaluated the effects of ketamine in rats with the comorbidity of CPSP and depression.
    Methods: We induced CPSP in rats by thoracotomy and screened for rats with or without depression-like phenotype by hierarchical cluster analysis based on the results of depression-related behavioral experiments. Subsequently, rats were intraperitoneally injected with ketamine (20 mg/kg) and were evaluated by mechanical withdrawal threshold, cold hyperalgesia test, sucrose preference test, forced swimming test, and open field test. The inflammatory-related cytokines (IL-1, IL-6, TNF-α, nuclear factor-kappaB), oxidative stress parameters (superoxide dismutase, malondialdehyde, glutathione, catalase), and brain-derived neurotrophic factor (BDNF) in rat hippocampus were detected.
    Results: In the hippocampus of rats with the comorbidity of CPSP and depression, IL-1, IL-6, TNF-α, nuclear factor-kappaB, and malondialdehyde were significantly increased, while superoxide dismutase, glutathione, catalase, and BDNF were significantly decreased. Ketamine relieved depression but did not attenuate hyperalgesia in CPSP rats. Additionally, ketamine reduced proinflammatory cytokines, inhibited oxidative stress, and elevated BDNF levels in rat hippocampus.
    Conclusions: Ketamine can rapidly relieve CPSP-induced depression in rats, which may be related to the reduction of proinflammatory cytokines, regulating oxidative stress and increasing BDNF in the hippocampus.
    Mesh-Begriff(e) Animals ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; Antidepressive Agents/pharmacology ; Antidepressive Agents/therapeutic use ; Antioxidants/pharmacology ; Antioxidants/therapeutic use ; Brain-Derived Neurotrophic Factor/biosynthesis ; Brain-Derived Neurotrophic Factor/genetics ; Depression/drug therapy ; Depression/metabolism ; Depression/psychology ; Gene Expression ; Hippocampus/drug effects ; Hippocampus/metabolism ; Ketamine/pharmacology ; Ketamine/therapeutic use ; Male ; Oxidative Stress/drug effects ; Oxidative Stress/physiology ; Pain, Postoperative/drug therapy ; Pain, Postoperative/metabolism ; Pain, Postoperative/psychology ; Rats ; Rats, Sprague-Dawley
    Chemische Substanzen Anti-Inflammatory Agents ; Antidepressive Agents ; Antioxidants ; Bdnf protein, rat ; Brain-Derived Neurotrophic Factor ; Ketamine (690G0D6V8H)
    Sprache Englisch
    Erscheinungsdatum 2020-03-03
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 130601-7
    ISSN 1432-2072 ; 0033-3158
    ISSN (online) 1432-2072
    ISSN 0033-3158
    DOI 10.1007/s00213-020-05490-3
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  10. Artikel: Energy extraction and hydrodynamic behavior analysis by an oscillating hydrofoil device

    Ma, Penglei / Haibin Liu / Yong Wang / Yudong Xie / Zhihong Yang

    Renewable energy. 2017 Dec., v. 113

    2017  

    Abstract: In this paper, a modified model is proposed for an oscillating foil energy harvesting device, and the corresponding mathematical model is established too. A grid model for foil NACA0015 is built by using dynamic and moving mesh technology of the ... ...

    Abstract In this paper, a modified model is proposed for an oscillating foil energy harvesting device, and the corresponding mathematical model is established too. A grid model for foil NACA0015 is built by using dynamic and moving mesh technology of the Computational Fluid Dynamics (CFD) software FLUENT. To understand the hydrodynamic performance and energy extraction capability of the modified model, the effects of motion parameters (heaving component parameters and pitching component parameters) are investigated. The evolutions of angle of attack and vortex field are examined. The results show that motion radius and heaving amplitude play important roles in impacting the time-averaged power coefficient. As the frequency increases, the peak value of the effective angle of attack is decline. The effect of pitching amplitude is gradually increased on the time-averaged power coefficient. Under the large frequency, the energy extraction efficiency is more sensitive to the motion radius and heaving amplitude. Moreover, there exists an optimal oscillation frequency to achieve a maximum time-averaged power coefficient for each pitching amplitude.
    Schlagwörter computer software ; energy ; foil ; hydrodynamics ; mathematical models ; renewable energy sources
    Sprache Englisch
    Erscheinungsverlauf 2017-12
    Umfang p. 648-659.
    Erscheinungsort Elsevier Ltd
    Dokumenttyp Artikel
    ZDB-ID 2001449-1
    ISSN 0960-1481
    ISSN 0960-1481
    DOI 10.1016/j.renene.2017.06.036
    Datenquelle NAL Katalog (AGRICOLA)

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