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  1. Article ; Online: Using interpretable machine learning to extend heterogeneous antibody-virus datasets.

    Einav, Tal / Ma, Rong

    Cell reports methods

    2023  Volume 3, Issue 8, Page(s) 100540

    Abstract: A central challenge in biology is to use existing measurements to predict the outcomes of future experiments. For the rapidly evolving influenza virus, variants examined in one study will often have little to no overlap with other studies, making it ... ...

    Abstract A central challenge in biology is to use existing measurements to predict the outcomes of future experiments. For the rapidly evolving influenza virus, variants examined in one study will often have little to no overlap with other studies, making it difficult to discern patterns or unify datasets. We develop a computational framework that predicts how an antibody or serum would inhibit any variant from
    MeSH term(s) Animals ; Humans ; Ferrets ; Antibodies ; Hemagglutination Inhibition Tests ; Machine Learning ; Oils, Volatile
    Chemical Substances Antibodies ; Oils, Volatile
    Language English
    Publishing date 2023-07-25
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2667-2375
    ISSN (online) 2667-2375
    DOI 10.1016/j.crmeth.2023.100540
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Designing Cancer Warning Labels for Alcoholic Beverages: Examining the Impact of Visual Elements.

    Ma, Zexin / Ma, Rong

    Health education & behavior : the official publication of the Society for Public Health Education

    2023  Volume 50, Issue 5, Page(s) 586–594

    Abstract: Alcohol is a known carcinogen. However, public awareness of cancer risk associated with alcohol use is low. A promising approach to raising awareness is to include cancer warning labels on alcohol-containing products, but there is limited knowledge of ... ...

    Abstract Alcohol is a known carcinogen. However, public awareness of cancer risk associated with alcohol use is low. A promising approach to raising awareness is to include cancer warning labels on alcohol-containing products, but there is limited knowledge of the design and effect of such warnings. The present study investigated the impact of visual elements on the effectiveness of cancer warning labels. In a randomized online experiment, alcohol consumers (
    MeSH term(s) Humans ; Smoking Cessation/psychology ; Alcoholic Beverages/adverse effects ; Alcohol Drinking/adverse effects ; Alcohol Drinking/prevention & control ; Alcohol Drinking/psychology ; Intention ; Ethanol ; Neoplasms/prevention & control
    Chemical Substances Ethanol (3K9958V90M)
    Language English
    Publishing date 2023-05-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1362906-2
    ISSN 1552-6127 ; 1090-1981
    ISSN (online) 1552-6127
    ISSN 1090-1981
    DOI 10.1177/10901981231166696
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Ablation for malignant liver tumor using high-intensity focused ultrasound and radio-frequency: A meta-analysis.

    Lai, Xing / Zhang, Songsong / Gong, Jianping / Ma, Rong

    Technology and health care : official journal of the European Society for Engineering and Medicine

    2024  

    Abstract: Background: Primary liver cancer is a major health issue, so finding the most effective treatment is vital.: Objective: The present meta-analysis compares high-intensity focused ultrasound (HIFU) to radiofrequency (RF) ablation for primary liver ... ...

    Abstract Background: Primary liver cancer is a major health issue, so finding the most effective treatment is vital.
    Objective: The present meta-analysis compares high-intensity focused ultrasound (HIFU) to radiofrequency (RF) ablation for primary liver cancer treatment.
    Methods: PubMed, MEDLINE, CNKI, VIP, and Wanfang were used to search for English and Chinese papers. After carefully confirming data completeness and applying inclusion and exclusion criteria, RevMan 5.3 was used to evaluate the included literature. Data analysis utilized a fixed-effects model for heterogeneity between 0.1 and 0.5.
    Results: The meta-analysis included 304 patients: 119 had HIFU and 185 RF ablation. For primary liver cancer, HIFU and RF ablation were equally efficacious (odds ratio 1.02, 95% confidence interval [0.54, 1.92]). Overall survival, disease-free survival, and complications at 1, 2, and 3 years were not significantly different (odds ratio 0.72, 95% confidence range [0.04, 12.79], P= 0.82).
    Conclusion: The meta-analysis shows no significant difference in efficacy, long-term survival rates, or complication rates between HIFU and RF ablation for primary liver cancer, but more large-scale, high-quality randomized clinical trials are needed to prove their equivalence. Both therapy strategies seem promising, but additional information is needed to determine their respective merits.
    Language English
    Publishing date 2024-02-29
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1159961-3
    ISSN 1878-7401 ; 0928-7329
    ISSN (online) 1878-7401
    ISSN 0928-7329
    DOI 10.3233/THC-230868
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Morphology and Phylogeny Reveal Three New Species of

    Wang, Shuo / Jiang, Ning / Ma, Rong

    Journal of fungi (Basel, Switzerland)

    2024  Volume 10, Issue 2

    Abstract: ... ...

    Abstract Cytospora
    Language English
    Publishing date 2024-02-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2784229-0
    ISSN 2309-608X ; 2309-608X
    ISSN (online) 2309-608X
    ISSN 2309-608X
    DOI 10.3390/jof10020139
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Trimethylamine N-oxide, choline and its metabolites are associated with the risk of non-alcoholic fatty liver disease.

    Ma, Rong / Shi, Guangying / Li, Yanfang / Shi, Han

    The British journal of nutrition

    2024  , Page(s) 1–9

    Abstract: It is inconclusive whether trimethylamine N-oxide (TMAO) and choline and related metabolites, namely trimethylamine (TMA), l-carnitine, betaine and dimethylglycine (DMG), are associated with non-alcoholic fatty liver disease (NAFLD). Our objective was to ...

    Abstract It is inconclusive whether trimethylamine N-oxide (TMAO) and choline and related metabolites, namely trimethylamine (TMA), l-carnitine, betaine and dimethylglycine (DMG), are associated with non-alcoholic fatty liver disease (NAFLD). Our objective was to investigate these potential associations. Additionally, we sought to determine the mediating role of TMAO. In this 1:1 age- and sex-matched case-control study, a total of 150 pairs comprising NAFLD cases and healthy controls were identified. According to the fully adjusted model, after the highest tertile was compared with the lowest tertile, the plasma TMAO concentration (OR = 2·02 (95 % CI 1·04, 3·92);
    Language English
    Publishing date 2024-03-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 280396-3
    ISSN 1475-2662 ; 0007-1145
    ISSN (online) 1475-2662
    ISSN 0007-1145
    DOI 10.1017/S0007114524000631
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Independent Validation of the BRENDA-Score Breast Cancer Prognosis Prediction Tool In Chinese Patients.

    Ma, Shao / Liu, Yunxia / Gao, Peng / Ma, Rong

    Clinical breast cancer

    2024  

    Abstract: Background: The BRENDA-Score was developed and used to predict the prognosis of patients with breast cancer (BC). This study was performed to validate the use of this tool in Chinese patients with primary invasive BC patients.: Methods: Patients ... ...

    Abstract Background: The BRENDA-Score was developed and used to predict the prognosis of patients with breast cancer (BC). This study was performed to validate the use of this tool in Chinese patients with primary invasive BC patients.
    Methods: Patients underwent surgery for BC from January 2009 to December 2016. Discrimination was assessed by the area under the receiver operating characteristic (ROC) curve (AUC). Calibrations were assessed by comparing predicted and observed 5-year and 10-year metastasis-free survival (MFS) in the overall cohort and patient subgroups.
    Results: A total of 2029 BC patients were enrolled. Kaplan-Meier analysis revealed significant differences in MFS risk groups (log-rank test P < .01). ROC analysis showed good accuracy for 5-year MFS (AUC 0.779) and fair accuracy for 10-year MFS (AUC 0.728). The BRENDA-Score accurately predicted 5-year and 10-year MFS in the entire cohort and in all other predefined subgroups, except for the 5-year MFS in the subgroup aged<40 years, which was overestimated (differences between the predicted and observed MFS were 6.7%, P < .05). The 5-year MFS rates of ER- positive and ER-negative patients were 90.9% and 80.6%, respectively (P < .05). The 10-year MFS rates of ER-positive and ER-negative patients were 78.0% and 73.7%, respectively (P = .25).
    Conclusions: The BRENDA-Score accurately predicted 5-year and 10-year MFS. The results showed good validity, transportability, and potential clinical value. However, the results for 5-years MFS should be interpreted carefully in patients aged <40 years. After 10 years the value of the ER as a prognostic factor was less important.
    Language English
    Publishing date 2024-02-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2106734-X
    ISSN 1938-0666 ; 1526-8209
    ISSN (online) 1938-0666
    ISSN 1526-8209
    DOI 10.1016/j.clbc.2024.02.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Melatonin's effect on hair follicles in a goat (

    Rong, Youjun / Ma, Rong / Zhang, Yanjun / Guo, Zhenhua

    Frontiers in endocrinology

    2024  Volume 15, Page(s) 1361100

    Abstract: Introduction: Melatonin can treat androgenetic alopecia in males. Goats can be used as animal models to study melatonin treatment for human alopecia. In this study, a meta-analysis of melatonin's effects on goat hair follicles was pursued.: Methods: ... ...

    Abstract Introduction: Melatonin can treat androgenetic alopecia in males. Goats can be used as animal models to study melatonin treatment for human alopecia. In this study, a meta-analysis of melatonin's effects on goat hair follicles was pursued.
    Methods: Literature from the last 20 years was searched in Scopus, Science Direct, Web of Science and PubMed. Melatonin's effect on goat hair follicles and litter size were performed through a traditional meta-analysis and trial sequential analysis. A network meta-analysis used data from oocyte development to blastocyst. The hair follicle genes regulated by melatonin performed KEGG and PPI. We hypothesized that there are differences in melatonin receptors between different goats, and therefore completed melatonin receptor 1A homology modelling and molecular docking.
    Results: The results showed that melatonin did not affect goat primary follicle or litter size. However, there was a positive correlation with secondary follicle growth. The goat
    Discussion: Future studies should focus on the relationship between goat SNPs and the effect of embedded melatonin. This study will provide theoretical guidance for the cashmere industry and will be informative for human alopecia research.
    MeSH term(s) Animals ; Humans ; Hair Follicle ; Melatonin/pharmacology ; Receptors, Melatonin/genetics ; Goats/genetics ; Molecular Docking Simulation ; Models, Animal ; Alopecia
    Chemical Substances Melatonin (JL5DK93RCL) ; Receptors, Melatonin
    Language English
    Publishing date 2024-04-02
    Publishing country Switzerland
    Document type Meta-Analysis ; Journal Article
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2024.1361100
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Clinical value of serum LINC02446 and S100B in early diagnosis and prognosis assessment of traumatic brain injury.

    Ma, Rong / Liu, Yu / Mao, Qing

    The International journal of neuroscience

    2024  , Page(s) 1–8

    Abstract: Objective: To detect the expression levels of LINC02446 and S100B in serum of patients with traumatic brain injury (TBI) and explore their values as diagnostic and prognostic indicators for TBI.: Method: Abnormal expressed RNAs in brain injury were ... ...

    Abstract Objective: To detect the expression levels of LINC02446 and S100B in serum of patients with traumatic brain injury (TBI) and explore their values as diagnostic and prognostic indicators for TBI.
    Method: Abnormal expressed RNAs in brain injury were screened from the dataset GSE1131475. Serums were collected from moderate to severe TBI patients at 1-3 and 4-12 h post injury. Quantitative polymerase chain reaction was used to detect the expression levels of LINC02446 and S100B in serum. The Glasgow Outcome Scale was used for prognostic evaluation. The diagnostic and prognostic efficacy of LINC02446 and S100B in TBI was evaluated using the receiver operating characteristic (ROC) curve.
    Result: The serum expression levels of LINC02446 and S100B in the TBI group were significantly increased. The expression levels of LINC02446 and S100B in the severe TBI group were significantly higher than those in the mild TBI group. ROC curve analysis showed that the combination of LINC02446 and S100B can distinguish TBI patients from healthy controls, as well as mild TBI from moderate to severe TBI. At the 6-month follow-up, the expression levels of LINC02446 and S100B in TBI patients with poor prognosis were significantly higher than those in patients with good prognosis, and ROC results showed their differentiation value. Moreover, the expression level of LINC02446 at 0-3 h can serve as an independent prognostic factor for poor prognosis.
    Conclusion: Serum LINC02446 and S100B hold clinical application value in the diagnosis and prognosis of TBI and are expected to become new potential biomarkers.
    Language English
    Publishing date 2024-04-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 3061-2
    ISSN 1563-5279 ; 1543-5245 ; 0020-7454
    ISSN (online) 1563-5279 ; 1543-5245
    ISSN 0020-7454
    DOI 10.1080/00207454.2024.2341929
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: How are we going to treat Chinese people during the pandemic? Media cultivation of intergroup threat and blame.

    Ma, Rong / Ma, Zexin

    Group processes & intergroup relations : GPIR

    2022  Volume 26, Issue 3, Page(s) 515–533

    Abstract: This study integrates cultivation and intergroup threat theories to examine media cultivation effects during the COVID-19 pandemic. We argue that U.S. media have consistently portrayed China as a threat and target of blame. The cultivation of media has ... ...

    Abstract This study integrates cultivation and intergroup threat theories to examine media cultivation effects during the COVID-19 pandemic. We argue that U.S. media have consistently portrayed China as a threat and target of blame. The cultivation of media has thus resulted in perceived threat of and blame on Chinese people for the COVID-19 pandemic. Results of a cross-sectional survey in two samples (MTurk:
    Language English
    Publishing date 2022-03-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 2021721-3
    ISSN 1461-7188 ; 1368-4302
    ISSN (online) 1461-7188
    ISSN 1368-4302
    DOI 10.1177/13684302221075695
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Social Media Use and Demographics Predicted Knowledge About Alcohol as a Cancer Risk Factor.

    Ma, Rong / Ma, Zexin

    American journal of health promotion : AJHP

    2022  Volume 36, Issue 6, Page(s) 1025–1028

    Abstract: Purpose: To determine whether social media use, alcohol consumption, and sociodemographic factors predicted Americans' knowledge about alcohol-related cancer risk.: Design: Health Information National Trends Survey (2020).: Setting: United States.! ...

    Abstract Purpose: To determine whether social media use, alcohol consumption, and sociodemographic factors predicted Americans' knowledge about alcohol-related cancer risk.
    Design: Health Information National Trends Survey (2020).
    Setting: United States.
    Subjects: A nationally representative sample (
    Measures: Knowledge about cancer risk of beer, wine, and liquor; social media use; demographics; smoking status; alcohol consumption; and cancer history.
    Analysis: Data were analyzed using multinomial multiple logistic regression with jackknife replicate weights.
    Results: Less than a third of U.S. adults (20.34-31.20%) were aware of cancer risk of alcohol. People who watched health-related YouTube videos were more likely to be well-informed (odds ratio [OR] = 1.55 [95% confidence interval 1.01, 2.36] for beer)
    Conclusion: Social media can be a source of both correct information and misinformation about alcohol and cancer risk. Health promotion should target older adults, people with less education, racial minorities, females, and people who consume alcohol.
    MeSH term(s) Aged ; Alcohol Drinking/adverse effects ; Alcohol Drinking/epidemiology ; Alcoholic Beverages ; Demography ; Female ; Humans ; Neoplasms/epidemiology ; Neoplasms/etiology ; Risk Factors ; Social Media ; United States/epidemiology
    Language English
    Publishing date 2022-04-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 645160-3
    ISSN 2168-6602 ; 0890-1171
    ISSN (online) 2168-6602
    ISSN 0890-1171
    DOI 10.1177/08901171221087098
    Database MEDical Literature Analysis and Retrieval System OnLINE

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