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Article ; Online: Prevalence of poor nutrition status in multiple sclerosis patients assessed by different diagnostic tools.

Mogiłko, Natalia / Malgorzewicz, Sylwia

2023 Volume 70, Issue 2, Page(s) 343–345

Abstract: Patients with multiple sclerosis (MS) present a spectrum of nutritional disorders from obesity to malnutrition. The purpose of this study was an assessment of the nutritional status of MS patients by NRS-2002 and GLIM criteria.: Methods: 147 patients ... ...

Abstract	Patients with multiple sclerosis (MS) present a spectrum of nutritional disorders from obesity to malnutrition. The purpose of this study was an assessment of the nutritional status of MS patients by NRS-2002 and GLIM criteria. Methods: 147 patients were included in the study. The nutritional status was assessed by NRS 2002, GLIM, and body composition analysis. The routine biochemical parameters were measured. Results: Deterioration of the nutritional status was observed in 87.8% of patients. GLIM criteria indicated that 20% of patients were malnourished and 80% were at risk. The percentage of patients with excess body mass was 46.8%, and of underweight patients was 6.6%. The risk of malnutrition was positively associated with low content of adipose tissue (R=-0.24; p=0.00), low BMI (R=-0.22; p=0.00), and higher weight loss in the last 6 months (R=0.47; p=0.00). Additionally, a significant (p<0.05) correlation between malnutrition state and s-albumin (R=-0.2) and CRP (R=0.23) was observed. Conclusion: Overweight and obesity concerned a large proportion of the studied group of MS patients, but this does not exclude the risk of malnutrition. Dietary care and regular outpatient nutritional status assessment should be provided throughout the disease.
MeSH term(s)	Humans ; Nutritional Status ; Prevalence ; Multiple Sclerosis/complications ; Multiple Sclerosis/epidemiology ; Malnutrition/diagnosis ; Malnutrition/epidemiology ; Obesity
Language	English
Publishing date	2023-05-31
Publishing country	Poland
Document type	Journal Article
ZDB-ID	595762-x
ISSN	1734-154X ; 0001-527X
ISSN (online)	1734-154X
ISSN	0001-527X
DOI	10.18388/abp.2020_6578
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Article ; Online: Re. Effectiveness of protein-caloric supplementation in hemodialysis patients to improve the amino acid balance and avoid protein energy wasting: Author's response.

Małgorzewicz, Sylwia

Nutrition (Burbank, Los Angeles County, Calif.)

2018 Volume 62, Page(s) 211

MeSH term(s)	Amino Acids ; Cachexia ; Dietary Supplements ; Humans ; Renal Dialysis
Chemical Substances	Amino Acids
Language	English
Publishing date	2018-11-24
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	639259-3
ISSN	1873-1244 ; 0899-9007
ISSN (online)	1873-1244
ISSN	0899-9007
DOI	10.1016/j.nut.2018.11.008
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Article ; Online: Profiles of Serum Fatty Acids in Healthy Women on Different Types of Vegetarian Diets.

Gogga, Patrycja / Mika, Adriana / Janczy, Agata / Sztendel, Alicja / Sledzinski, Tomasz / Małgorzewicz, Sylwia

Nutrients

2024 Volume 16, Issue 4

Abstract: Background: Plant-based dietary patterns are a source of different amounts and proportions of fatty acids (FAs) from those in traditional diets. Information about the full FAs profile provided by plant-based diets is widely lacking. The aim of this ... ...

Abstract	Background: Plant-based dietary patterns are a source of different amounts and proportions of fatty acids (FAs) from those in traditional diets. Information about the full FAs profile provided by plant-based diets is widely lacking. The aim of this study was to present the exact serum profiles of FAs among people on a plant-based diet compared with omnivorous subjects. Methods: FAs compositions and inflammation statuses (based on serum C-reactive protein (CRP) levels) were studied in serum samples obtained from 102 female volunteers (divided into four groups: vegans, vegetarians, pescatarians, and omnivores). The quality of the volunteers' diets was assessed based on seven-day dietary records. Results: Both vegans and vegetarians had lower total Conclusion: The analysis of serum FAs and CRP levels in vegetarians and vegans suggests that factors other than diet alone influence inflammation and overall health status. Further research on long-term plant-based diet users is needed to better understand this issue, and supplementation with EPA and DHA is worth considering in vegans and vegetarians.
MeSH term(s)	Humans ; Female ; Fatty Acids ; Diet, Vegetarian ; Diet ; Vegetarians ; Diet, Vegan ; Health Status ; Inflammation
Chemical Substances	Fatty Acids
Language	English
Publishing date	2024-02-13
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu16040516
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Article ; Online: Dietary Lipids and Dyslipidemia in Chronic Kidney Disease

Kochan, Zdzislaw / Szupryczynska, Natalia / Malgorzewicz, Sylwia / Karbowska, Joanna

Nutrients. 2021 Sept. 09, v. 13, no. 9

2021

Abstract: The progression of chronic kidney disease (CKD) leads to altered lipid metabolism. CKD patients exhibit high blood triglyceride (TG) levels, reduced concentrations and functionality of high-density lipoproteins (HDL), and elevated levels of atherogenic ... ...

Abstract	The progression of chronic kidney disease (CKD) leads to altered lipid metabolism. CKD patients exhibit high blood triglyceride (TG) levels, reduced concentrations and functionality of high-density lipoproteins (HDL), and elevated levels of atherogenic small, dense, low-density lipoproteins (sdLDL). Disorders of lipid metabolism and other metabolic disturbances place CKD patients at high risk for cardiovascular disease (CVD). Extensive evidence supports the cardioprotective effects of unsaturated fatty acids, including their beneficial effect on serum cholesterol and TG levels. Dietary lipids might therefore be especially important in the nutritional management of CKD. We review current dietary recommendations for fat intake by CKD patients and suggest potential nutritional interventions by emphasizing dietary lipids that might improve the blood lipid profile and reduce cardiovascular risk in CKD.
Keywords	blood lipids ; cardioprotective effect ; cardiovascular diseases ; cholesterol ; diet-related diseases ; dietary fat ; dietary recommendations ; fat intake ; high density lipoprotein ; highly unsaturated fatty acids ; hyperlipidemia ; kidney diseases ; lipemic effect ; lipid metabolism ; low density lipoprotein ; nutritional intervention ; triacylglycerols
Language	English
Dates of publication	2021-0909
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article ; Online
ZDB-ID	2518386-2
ISSN	2072-6643
ISSN	2072-6643
DOI	10.3390/nu13093138
Database	NAL-Catalogue (AGRICOLA)

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Article: Impact of allergic diseases on fertility.

Wasilewska, Eliza / Małgorzewicz, Sylwia

Postepy dermatologii i alergologii

2019 Volume 36, Issue 5, Page(s) 507–512

Abstract: The incidence of allergic diseases has been increasing in recent decades, and currently, nearly 30% of the European population suffer from some type of allergy. Also, an increasing number of people are suffering from infertility. Both diseases are ... ...

Abstract	The incidence of allergic diseases has been increasing in recent decades, and currently, nearly 30% of the European population suffer from some type of allergy. Also, an increasing number of people are suffering from infertility. Both diseases are related to the hormonal and immune systems, which prompts the question as to whether there is a causal relationship between allergic disorders and the reproductive system. The purpose of this review is to evaluate whether there is a link between allergic diseases and infertility, using the available literature.
Language	English
Publishing date	2019-11-12
Publishing country	Poland
Document type	Journal Article ; Review
ZDB-ID	2596142-1
ISSN	1642-395X
ISSN	1642-395X
DOI	10.5114/ada.2019.89501
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Article: The influence of nutritional habits, body mass index and intestinal microbiota in mastocytosis on clinical symptoms using conventional culture and next generation sequencing.

Harcęko-Zielińska, Ewelina / Niedoszytko, Marek / Górska, Aleksandra / Małgorzewicz, Sylwia / Gruchała-Niedoszytko, Marta / Bronk, Marek / Dąbrowski, Slawomir / Chełminska, Marta / Jassem, Ewa

Clinical and translational allergy

2024 Volume 14, Issue 1, Page(s) e12310

Abstract: Background: Mastocytosis is a rare neoplastic disease of the bone marrow associated with the proliferation and accumulation of mast cells in various internal organs, including the gastrointestinal tract. There are few studies describing the gut ... ...

Abstract	Background: Mastocytosis is a rare neoplastic disease of the bone marrow associated with the proliferation and accumulation of mast cells in various internal organs, including the gastrointestinal tract. There are few studies describing the gut microbiome of patients with mastocytosis using next generation sequencing supported using traditional culture methods. The aims of the study were, firstly, the determination of nutrition habits, composition of the intestinal microflora and BMI in mastocytosis, and secondly, analysis of mastocytosis severity and symptoms depending on the composition of the intestinal microflora. Methods: The study included 47 patients with indolent systemic mastocytosis and 18 healthy controls. All participants gave their informed consent to participate in the study. The study consisted of 3 parts: I-clinical assessment, II - examination of the intestinal microflora using the biochemical method, III - 16S rRNA sequencing. Results: The nutrition habits and BMI of mastocytosis patients were similar to controls; however, most patients with mastocytosis had a low dietary vitamin and mineral content. As many as 94.5% of patients had too little fiber intake and mineral content. The most common cause of the abnormal stool test result with traditional culture was a titer of E. coli <10 Conclusions: The nutritional habits and BMI of mastocytosis patients are similar to the general population, except for too little fiber intake and mineral content. The gastrointestinal symptoms of mastocytosis patients may be related to the low richness of microbiota species and the amount of Suterella, Barnesiellaceae, Eubacterium, Odoribacter, Anaerostipes, which correlated with tryptase levels.
Language	English
Publishing date	2024-01-28
Publishing country	England
Document type	Journal Article
ZDB-ID	2630865-4
ISSN	2045-7022
ISSN	2045-7022
DOI	10.1002/clt2.12310
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Article ; Online: Mediterranean, vegetarian and vegan diets as practical outtakes of EAS and ACC/AHA recommendations for lowering lipid profile.

Wojda, Anna / Janczy, Agata / Małgorzewicz, Sylwia

Acta biochimica Polonica

2021 Volume 68, Issue 1, Page(s) 41–48

Abstract: Reduction of total cholesterol (TC) and LDL fraction (LDL-C) may be beneficial towards decreasing the risk of development of cardiovascular diseases (CVD). First and foremost, before implementing or simultaneously with pharmacological treatment, patients ...

Abstract	Reduction of total cholesterol (TC) and LDL fraction (LDL-C) may be beneficial towards decreasing the risk of development of cardiovascular diseases (CVD). First and foremost, before implementing or simultaneously with pharmacological treatment, patients should be informed about lifestyle changes that may be critical to achieving a better lipid profile. Recommendations from ACC/AHA (American College of Cardiology and American Heart Association) and EAS (European Atherosclerosis Society) mainly focus on limitation of saturated fatty acids (SFA) and trans fatty acids (TFA) consumption, but additional support could be considered. This review presents selected guidelines of European scientific societies concerning lipid metabolism disorders. The main aim of this manuscript was to present the guidelines how to provide simple and transparent schemes of management in dyslipidemia therapy. Encouraging patients for increasing the intake of soluble fiber (SF) and phytosterols (PS) may also be promoted for achieving therapeutic goals. In the clinical point of view, restoring an appropriate lipid profile is important because it directly reduces the risk of developing atherosclerotic cardiovascular disease (ASCVD). The EAS and ACC/AHA guidelines introduce several new demands, so far absent from previous recommendations. Mediterranean diet (MD) or vegetarian lifestyles are an example of diet patterns that are deliberated as healthy for cardio-vascular system, since both consist of fresh, unprocessed vegetables and fruits with addition of desirable fats.
MeSH term(s)	American Heart Association ; Atherosclerosis/epidemiology ; Atherosclerosis/prevention & control ; Cholesterol, LDL/blood ; Diet, Healthy/methods ; Diet, Mediterranean ; Diet, Vegan/methods ; Dyslipidemias/blood ; Dyslipidemias/diet therapy ; Dyslipidemias/epidemiology ; Humans ; Risk Factors ; United States/epidemiology
Chemical Substances	Cholesterol, LDL
Language	English
Publishing date	2021-02-05
Publishing country	Poland
Document type	Journal Article ; Practice Guideline ; Review
ZDB-ID	595762-x
ISSN	1734-154X ; 0001-527X
ISSN (online)	1734-154X
ISSN	0001-527X
DOI	10.18388/abp.2020_5515
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Article ; Online: Dietary Lipids and Dyslipidemia in Chronic Kidney Disease.

Kochan, Zdzislaw / Szupryczynska, Natalia / Malgorzewicz, Sylwia / Karbowska, Joanna

Nutrients

2021 Volume 13, Issue 9

Abstract	The progression of chronic kidney disease (CKD) leads to altered lipid metabolism. CKD patients exhibit high blood triglyceride (TG) levels, reduced concentrations and functionality of high-density lipoproteins (HDL), and elevated levels of atherogenic small, dense, low-density lipoproteins (sdLDL). Disorders of lipid metabolism and other metabolic disturbances place CKD patients at high risk for cardiovascular disease (CVD). Extensive evidence supports the cardioprotective effects of unsaturated fatty acids, including their beneficial effect on serum cholesterol and TG levels. Dietary lipids might therefore be especially important in the nutritional management of CKD. We review current dietary recommendations for fat intake by CKD patients and suggest potential nutritional interventions by emphasizing dietary lipids that might improve the blood lipid profile and reduce cardiovascular risk in CKD.
MeSH term(s)	Dyslipidemias/etiology ; Dyslipidemias/prevention & control ; Humans ; Lipids/administration & dosage ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency, Chronic/diet therapy ; Renal Insufficiency, Chronic/metabolism
Chemical Substances	Lipids
Language	English
Publishing date	2021-09-09
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu13093138
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Article ; Online: Fasting and postprandial ghrelin changes in older and younger volunteers.

Dardzińska, Jolanta A / Wernio, Edyta / Małgorzewicz, Sylwia

Minerva endocrinology

2021

Abstract: Background: Little evidence is available on how both forms of ghrelin change during the aging process. Most of the earlier studies measured only total ghrelin levels and mainly in the fasting state. This study aimed to assess periprandial changes of ... ...

Abstract	Background: Little evidence is available on how both forms of ghrelin change during the aging process. Most of the earlier studies measured only total ghrelin levels and mainly in the fasting state. This study aimed to assess periprandial changes of acylated and desacylated ghrelin (AG, DAG) in volunteers aged ≥65 and <65 years and to establish an association between both forms of ghrelin and nutritional status in older volunteers. Methods: Venous blood for serum AG and DAG assays were collected in sixty volunteers after an overnight fast and two hours after the consumption of a standard 300 kcal-mixed meal. In those aged 65 years or more nutritional status was assessed. Results: Levels of DAG and AG were lower in older compared to younger volunteers in the fasting state as well as postprandially. DAG levels after a meal decreased in older, but not in younger subjects. However, significantly higher levels of postprandial AG were found in subjects with a risk of malnutrition and those with reduced appetite in comparison to wellnourished ones. Interestingly, elderly subjects with the lowest insulin and BMI had the lowest fasting AG levels and subjects with too high BMI and hyperinsulinemia presented also the highest fasting AG levels. Conclusions: In older subjects, levels of both forms of ghrelin were lower and differential postprandial AG and DAG responses were observed when compared to younger subjects.
Language	English
Publishing date	2021-04-15
Document type	Journal Article
ISSN	2724-6116
ISSN (online)	2724-6116
DOI	10.23736/S2724-6507.21.03407-6
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Article: Dietary Patterns of Treatment–Resistant Depression Patients

Mechlińska, Agnieszka / Włodarczyk, Adam / Gruchała-Niedoszytko, Marta / Małgorzewicz, Sylwia / Cubała, Wiesław Jerzy

Nutrients. 2022 Sept. 13, v. 14, no. 18

2022

Abstract: Depression is a common mental disorder that occurs all over the world with treatment resistance commonly seen in clinical practice. Ketamine exhibits an antidepressant that is more often used in the case of treatment-resistant depression (TRD) in MDD and ...

Abstract	Depression is a common mental disorder that occurs all over the world with treatment resistance commonly seen in clinical practice. Ketamine exhibits an antidepressant that is more often used in the case of treatment-resistant depression (TRD) in MDD and BP. Research emphasizes that a healthy diet and the nutrients it contains can lower the risk of developing depression and form a strategy that supports conventional treatment. The aim of the study was to evaluate the patients’ diet and to analyze the effect of ketamine on food intake among patients with TRD. The study involved 15 patients suffering from treatment-resistant depression and 15 healthy volunteers. The data required for the analysis were collected using the food frequency questionnaire (FFQ) and 4-day food diaries. The study group was statistically significantly less likely to consume milk and plain milk beverages, plain white cheese, wholemeal bread, various vegetables, wine, and drinks. Our results show several disorders in the eating habits of patients with treatment–resistant depression. After the administration of ketamine, the patients consumed significantly less protein, fats, monounsaturated fatty acids (MUFA) and polyunsaturated fatty acids (PUFA), fiber, tryptophan, vitamins, and minerals compared to the control group. There is a lack of research describing the effects of ketamine on nutrition. In order to confirm the results of the study, more participants are required, and the assessment of food diaries filled in at the patient’s home with a longer interval after the last dose of ketamine as well.
Keywords	antidepressants ; behavior disorders ; food frequency questionnaires ; food intake ; healthy diet ; ketamine ; milk ; patients ; risk ; tryptophan ; white cheeses ; whole wheat bread ; wines
Language	English
Dates of publication	2022-0913
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2518386-2
ISSN	2072-6643
ISSN	2072-6643
DOI	10.3390/nu14183766
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