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  1. Article ; Online: Is there an association between intimate partner violence and the prevalence of cervical cancer screening in Jordan?

    Urquhart, Grace / Maclennan, Sara J / Guntupalli, Aravinda Meera

    PloS one

    2023  Volume 18, Issue 8, Page(s) e0290678

    Abstract: Background: Major health inequalities exist surrounding the utilisation of cervical cancer screening services globally. Jordan, a low- and middle-income country, has poor screening rates (15.8%), with barriers to accessing services, including lack of ... ...

    Abstract Background: Major health inequalities exist surrounding the utilisation of cervical cancer screening services globally. Jordan, a low- and middle-income country, has poor screening rates (15.8%), with barriers to accessing services, including lack of education. Emerging studies demonstrate that intimate partner violence (IPV) impacts reproductive health decisions. As a large proportion of Jordanian women have reported experiencing IPV, this study examines the association between IPV and cervical cancer screening in Jordan, the first of its kind using national-level data.
    Methods: Using Jordan's Demographic Health Survey 2017-18, cervical cancer screening awareness and self-reported screening were estimated in participants who answered questions on IPV (n = 6679). After applying sample weights, Heckman's two-stage probit model determined the association of awareness and utilisation of cervical cancer screening with experience of IPV, adjusting for the socio-economic factors.
    Results: Of the women with privacy to answer the IPV module, 180 (3.4%) were found to be victims of sexual violence, 691 of physical violence (12.6%) and 935 (16.2%) of emotional violence. Women subjected to sexual violence were less likely to admit to having awareness of a Pap smear test; however, this did not impact screening rates. Victims of emotional violence were more likely to be screened than non-victims. No association between physical violence and cervical cancer screening was found.
    Conclusions: A significant association between cervical screening awareness and IPV demonstrates that cancer screening policies must consider IPV among women to improve screening awareness. The paper further sheds light on the paradoxical association between emotional violence and screening. It is acknowledged this situation may be far worse than reported, as women without autonomy were unlikely to answer IPV questions that may endanger them-targeted surveys on cervical cancer screening warrant further investigation.
    MeSH term(s) Humans ; Female ; Early Detection of Cancer ; Uterine Cervical Neoplasms/diagnosis ; Uterine Cervical Neoplasms/epidemiology ; Jordan/epidemiology ; Prevalence ; Intimate Partner Violence
    Language English
    Publishing date 2023-08-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0290678
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Treatment burden in survivors of prostate and colorectal cancers: a qualitative interview study.

    Adam, Rosalind / Duncan, Lisa / Maclennan, Sara J / Locock, Louise

    BMJ open

    2023  Volume 13, Issue 3, Page(s) e068997

    Abstract: Objectives: Treatment burden is the workload of healthcare and the impact this has on the individual. Treatment burden is associated with poorer patient outcomes in several chronic diseases. Illness burden has been extensively studied in cancer, but ... ...

    Abstract Objectives: Treatment burden is the workload of healthcare and the impact this has on the individual. Treatment burden is associated with poorer patient outcomes in several chronic diseases. Illness burden has been extensively studied in cancer, but little is known about treatment burden, particularly in those who have completed primary treatment for cancer. The aim of this study was to investigate treatment burden in survivors of prostate and colorectal cancers and their caregivers.
    Design: Semistructured interview study. Interviews were analysed using Framework and thematic analysis.
    Setting: Participants were recruited via general practices in Northeast Scotland.
    Participants: Eligible participants were individuals who had been diagnosed with colorectal or prostate cancer without distant metastases within the previous 5 years and their caregivers. Thirty-five patients and six caregivers participated: 22 patients had prostate and 13 had colorectal cancers (six male, seven female).
    Results: The term 'burden' did not resonate with most survivors, who expressed gratitude that time invested in cancer care could translate into improved survival. Cancer management was time consuming, but workload reduced over time. Cancer was usually considered as a discrete episode. Individual, disease and health system factors protected against or increased treatment burden. Some factors, such as health service configuration, were potentially modifiable. Multimorbidity contributed most to treatment burden and influenced treatment decisions and engagement with follow-up. The presence of a caregiver protected against treatment burden, but caregivers also experienced burden.
    Conclusions: Intensive cancer treatment and follow-up regimens do not necessarily lead to perceived burden. A cancer diagnosis serves as a strong motivator to engage in health management, but a careful balance exists between positive perceptions and burden. Treatment burden could lead to poorer cancer outcomes by influencing engagement with and decisions about care. Clinicians should ask about treatment burden and its impact, particularly in those with multimorbidity.
    Trial registration number: NCT04163068.
    MeSH term(s) Humans ; Male ; Prostate ; Prostatic Neoplasms ; Pelvis ; Survivors ; Colorectal Neoplasms
    Language English
    Publishing date 2023-03-03
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2022-068997
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Health status and associated factors of middle-aged and older adult cancer survivors in India: results from the Longitudinal Ageing Study in India.

    Guntupalli, Aravinda Meera / Selvamani, Y / Maclennan, Sara J / Dilip, T R

    BMC cancer

    2022  Volume 22, Issue 1, Page(s) 1087

    Abstract: Background: The number of persons who have survived cancer has been increasing in India as elsewhere due to advances in detection and treatment of this disease. However, evidence on the standardised number of cancer survivors, their characteristics and ... ...

    Abstract Background: The number of persons who have survived cancer has been increasing in India as elsewhere due to advances in detection and treatment of this disease. However, evidence on the standardised number of cancer survivors, their characteristics and their complex health challenges on a national level does not exist due to data limitations. This study, therefore, examines the profile of cancer survivors and their health status using the recently released Longitudinal Ageing Study in India (LASI) survey data.
    Methods: LASI wave 1 is a cross-sectional nationally representative survey of 65,562 middle and older adults aged 45 and above. We first calculated the socioeconomic, demographic and geographical characteristics of cancer survivors (per 100,000 population). We later estimated the adjusted odds of poor health, sleep problems, depressive symptoms, activities of living limitations (ADL and IADL), and hospitalisation of cancer survivors using multivariable logistic regression analysis.
    Results: According to LASI estimates, there were 2.1 million cancer survivors in India (95% CI 1.8 million to 2.6 million) in 2017-18. Overall, 440 cancer survivors have been identified in this study, with considerable state variations. The number of cancer survivors per 1,00,000 population was relatively more in non-indigenous groups, people with a history of cancer in their families, those who worked earlier but currently not working and those in the richest quintile categories. As compared to those who never had cancer, the cancer survivors are at higher risk of hospitalisation (adjusted odds ratio (aOR) = 2.61 CI 1.86, 3.67), poor self-rated health (aOR = 3.77, CI 2.55, 5.54), depressive symptoms (aOR = 1.53, CI 1.41, 2.05) and sleep problems (aOR = 2.29, CI 1.50, 3.47). They also reported higher ADL (aOR = 1.61, CI 1.11, 2.34) and IADL (aOR = 1.49, CI 1.07, 2.07) limitations. Cancer survivors who had their cancer diagnosis in the past 2 years or a cancer-related treatment in the past 2 years have significantly higher odds of poor health status than middle-aged and older adults without a cancer history.
    Conclusion: Middle-aged and older cancer survivors, particularly those who underwent cancer diagnosis or treatment in the past 2 years, are at a significantly higher risk of experiencing poor self-reported health and other health challenges, suggesting the need for an integrated healthcare approach.
    MeSH term(s) Middle Aged ; Humans ; Aged ; Cross-Sectional Studies ; Cancer Survivors ; Health Status ; Aging ; India/epidemiology ; Neoplasms/epidemiology ; Neoplasms/therapy ; Sleep Wake Disorders
    Language English
    Publishing date 2022-10-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041352-X
    ISSN 1471-2407 ; 1471-2407
    ISSN (online) 1471-2407
    ISSN 1471-2407
    DOI 10.1186/s12885-022-10111-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Patient-centered Care in Maternity Services: A Critical Appraisal and Synthesis of the Literature.

    de Labrusse, Claire / Ramelet, Anne-Sylvie / Humphrey, Tracy / Maclennan, Sara J

    Women's health issues : official publication of the Jacobs Institute of Women's Health

    2016  Volume 26, Issue 1, Page(s) 100–109

    Abstract: Background: Patient-centered care (PCC) has been recognized as a marker of quality in health service delivery. In policy documents, PCC is often used interchangeably with other models of care. There is a wide literature about PCC, but there is a lack of ...

    Abstract Background: Patient-centered care (PCC) has been recognized as a marker of quality in health service delivery. In policy documents, PCC is often used interchangeably with other models of care. There is a wide literature about PCC, but there is a lack of evidence about which model is the most appropriate for maternity services specifically.
    Aim: We sought to identify and critically appraise the literature to identify which definition of PCC is most relevant for maternity services.
    Methods: The four-step approach used to identify definitions of PCC was to 1) search electronic databases using key terms (1995-2011), 2) cross-reference key papers, 3) search of specific journals, and 4) search the grey literature. Four papers and two books met our inclusion criteria.
    Analysis: A four-criteria critical appraisal tool developed for the review was used to appraise the papers and books.
    Main results: From the six identified definitions, the Shaller's definition met the majority of the four criteria outlined and seems to be the most relevant to maternity services because it includes physiologic conditions as well as pathology, psychological aspects, a nonmedical approach to care, the greater involvement of family and friends, and strategies to implement PCC.
    Conclusion: This review highlights Shaller's definitions of PCC as the one that would be the most inclusive of all women using maternity services. Future research should concentrate on evaluating programs that support PCC in maternity services, and testing/validating this model of care.
    MeSH term(s) Delivery of Health Care/methods ; Female ; Humans ; Maternal Health Services/organization & administration ; Patient-Centered Care ; Pregnancy ; Quality of Health Care
    Language English
    Publishing date 2016-01
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1085396-0
    ISSN 1878-4321 ; 1049-3867
    ISSN (online) 1878-4321
    ISSN 1049-3867
    DOI 10.1016/j.whi.2015.09.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Diagnostic and prognostic factors in patients with prostate cancer: a systematic review protocol.

    Beyer, Katharina / Moris, Lisa / Lardas, Michael / Haire, Anna / Barletta, Francesco / Scuderi, Simone / Vradi, Eleni / Gandaglia, Giorgio / Omar, Muhammad Imran / MacLennan, Steven / Zong, Jihong / Farahmand, Bahman / Maclennan, Sara J / Devecseri, Zsuzsanna / Asiimwe, Alex / Collette, Laurence / Bjartell, Anders / Ndow, James / Briganti, Alberto /
    Van Hemelrijck, Mieke

    BMJ open

    2021  Volume 11, Issue 2, Page(s) e040531

    Abstract: Introduction: As part of the PIONEER (Prostate Cancer Diagnosis and Treatment Enhancement Through the Power of Big Data in Europe) Consortium, we will explore which diagnostic and prognostic factors (DPFs) are currently being researched to previously ... ...

    Abstract Introduction: As part of the PIONEER (Prostate Cancer Diagnosis and Treatment Enhancement Through the Power of Big Data in Europe) Consortium, we will explore which diagnostic and prognostic factors (DPFs) are currently being researched to previously defined clinical and patient-reported outcomes for prostate cancer (PCa).
    Methods and analysis: This research project will follow the following four steps: (1) a broad systematic literature review of DPFs for all stages of PCa, covering evidence from 2014 onwards; (2) discussion of systematic review findings by a multidisciplinary expert panel; (3) risk of bias assessment and applicability with Prediction model Risk Of Bias Assessment Tool criteria, Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) and the Quality In Prognosis Studies tool (QUIPS) and (4) additional quantitative assessments if required.
    Ethics and dissemination: We aim to develop an online tool to present the DPFs identified in this research and make them available across all stakeholders. There are no ethical implications.
    MeSH term(s) Bias ; Europe ; Humans ; Male ; Prognosis ; Prostatic Neoplasms/diagnosis ; Systematic Reviews as Topic
    Language English
    Publishing date 2021-02-11
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2020-040531
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Diagnostic and prognostic factors in patients with prostate cancer: a systematic review.

    Beyer, Katharina / Moris, Lisa / Lardas, Michael / Haire, Anna / Barletta, Francesco / Scuderi, Simone / Molnar, Megan / Herrera, Ronald / Rauf, Abdul / Campi, Riccardo / Greco, Isabella / Shiranov, Kirill / Dabestani, Saeed / van den Broeck, Thomas / Arun, Sujenthiran / Gacci, Mauro / Gandaglia, Giorgio / Omar, Muhammad Imran / MacLennan, Steven /
    Roobol, Monique J / Farahmand, Bahman / Vradi, Eleni / Devecseri, Zsuzsanna / Asiimwe, Alex / Zong, Jihong / Maclennan, Sara J / Collette, Laurence / NDow, James / Briganti, Alberto / Bjartell, Anders / Van Hemelrijck, Mieke

    BMJ open

    2022  Volume 12, Issue 4, Page(s) e058267

    Abstract: Objectives: As part of the PIONEER Consortium objectives, we have explored which diagnostic and prognostic factors (DPFs) are available in relation to our previously defined clinician and patient-reported outcomes for prostate cancer (PCa).: Design: ... ...

    Abstract Objectives: As part of the PIONEER Consortium objectives, we have explored which diagnostic and prognostic factors (DPFs) are available in relation to our previously defined clinician and patient-reported outcomes for prostate cancer (PCa).
    Design: We performed a systematic review to identify validated and non-validated studies.
    Data sources: MEDLINE, Embase and the Cochrane Library were searched on 21 January 2020.
    Eligibility criteria: Only quantitative studies were included. Single studies with fewer than 50 participants, published before 2014 and looking at outcomes which are not prioritised in the PIONEER core outcome set were excluded.
    Data extraction and synthesis: After initial screening, we extracted data following the Checklist for Critical Appraisal and Data Extraction for Systematic Reviews of prognostic factor studies (CHARMS-PF) criteria and discussed the identified factors with a multidisciplinary expert group. The quality of the included papers was scored for applicability and risk of bias using validated tools such as PROBAST, Quality in Prognostic Studies and Quality Assessment of Diagnostic Accuracy Studies 2.
    Results: The search identified 6604 studies, from which 489 DPFs were included. Sixty-four of those were internally or externally validated. However, only three studies on diagnostic and seven studies on prognostic factors had a low risk of bias and a low risk concerning applicability.
    Conclusion: Most of the DPFs identified require additional evaluation and validation in properly designed studies before they can be recommended for use in clinical practice. The PIONEER online search tool for DPFs for PCa will enable researchers to understand the quality of the current research and help them design future studies.
    Ethics and dissemination: There are no ethical implications.
    MeSH term(s) Bias ; Humans ; Male ; Mass Screening ; Prognosis ; Prostatic Neoplasms/diagnosis
    Language English
    Publishing date 2022-04-04
    Publishing country England
    Document type Journal Article ; Systematic Review
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2021-058267
    Database MEDical Literature Analysis and Retrieval System OnLINE

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