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Article ; Online: Salivary Testosterone and Sexual Function and Behavior in Men and Women: Findings from the Third British National Survey of Sexual Attitudes and Lifestyles (Natsal-3).

Macdowall, W G / Clifton, S / Palmer, M J / Tanton, C / Copas, A J / Lee, D M / Mitchell, K R / Mercer, C H / Sonnenberg, P / Johnson, A M / Wellings, K

Journal of sex research

2021  Volume 59, Issue 2, Page(s) 135–149

Abstract: Using data from the third British National Survey of Sexual Attitudes and Lifestyles (Natsal-3) we examined associations between salivary testosterone (Sal-T) and sexual function and behavior. Single morning saliva samples were self-collected from a ... ...

Abstract Using data from the third British National Survey of Sexual Attitudes and Lifestyles (Natsal-3) we examined associations between salivary testosterone (Sal-T) and sexual function and behavior. Single morning saliva samples were self-collected from a subsample of participants aged 18-74 years and analyzed using mass spectrometry. 1,599 men and 2,123 women were included in the analysis (40.6% of those invited to provide a sample). We adjusted for confounders in a stepwise manner: in model 1 we adjusted for age only; model 2 for age, season and relationship status, and model 3 we added BMI and self-reported health. In the fully adjusted models, among men, Sal-T was positively associated with both partnered sex (vaginal sex and concurrent partners) and masturbation. Among women, Sal-T was positively associated with masturbation, the only association with partnered sex was with ever experience of same-sex sex. We found no clear association between Sal-T and sexual function. Our study contributes toward addressing the sparsity of data outside the laboratory on the differences between men and women in the relationship between T and sexual function and behavior. To our knowledge, this is the first population study, among men and women, using a mass spectrometry Sal-T assay to do so.
MeSH term(s) Attitude ; Female ; Health Surveys ; Humans ; Life Style ; Male ; Sexual Behavior ; Sexual Partners ; Testosterone ; United Kingdom/epidemiology
Chemical Substances Testosterone (3XMK78S47O)
Language English
Publishing date 2021-10-11
Publishing country United States
Document type Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID 220889-1
ISSN 1559-8519 ; 0022-4499
ISSN (online) 1559-8519
ISSN 0022-4499
DOI 10.1080/00224499.2021.1968327
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