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  1. Article ; Online: Blood pressure medication should be routinely dosed at bedtime. An internist's critical appraisal of the editorial by Rainhold Kreutz et al. (2020). Blood pressure medication should not be routinely dosed at bedtime. We must disregard the data from the HYGIA project. Blood Pressure. 29 (3):135-136.

    Machado, António Pedro

    Chronobiology international

    2020  Volume 37, Issue 5, Page(s) 767–770

    Abstract: The history of hypertension the past hundred years is a successful story of the fall of myths, beliefs, and assumptions under the weight of evidence. The recent editorial by Kreutz et al. (2020), ...

    Abstract The history of hypertension the past hundred years is a successful story of the fall of myths, beliefs, and assumptions under the weight of evidence. The recent editorial by Kreutz et al. (2020),
    MeSH term(s) Antihypertensive Agents/therapeutic use ; Blood Pressure ; Blood Pressure Monitoring, Ambulatory ; Chronotherapy ; Circadian Rhythm ; Humans ; Hypertension/drug therapy ; Portugal
    Chemical Substances Antihypertensive Agents
    Language English
    Publishing date 2020-07-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 998996-1
    ISSN 1525-6073 ; 0742-0528
    ISSN (online) 1525-6073
    ISSN 0742-0528
    DOI 10.1080/07420528.2020.1781358
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2068: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Book: Guidelines for action plans for animal species

    Machado, Antonio

    planning recovery

    (Nature and environment ; 92)

    2001  

    Author's details by Antonio Machado
    Series title Nature and environment ; 92
    Collection
    Language English
    Size 76 S. : graph. Darst.
    Edition reprint.
    Publisher Council of Europe Publ
    Publishing place Strasbourg
    Publishing country France
    Document type Book
    HBZ-ID HT014862706
    ISBN 92-871-3472-3 ; 978-92-871-3472-1
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    064/965 available for loan (reading room) Freihandmagazin (U1)

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  3. Article ; Online: The time has come to change ambulatory blood pressure monitoring from 24-hour to 48-hour for the diagnosis of hypertension and cardiovascular risk assessment.

    Machado, António Pedro

    Revista portuguesa de cardiologia

    2018  Volume 37, Issue 4, Page(s) 329–331

    Title translation Chegou a altura de abandonar a MAPA de 24 horas e adotar a de 48 horas para o diagnóstico de hipertensão e correta avaliação do risco cardiovascular.
    MeSH term(s) Blood Pressure ; Blood Pressure Monitoring, Ambulatory ; Cardiovascular Diseases ; Humans ; Hypertension ; Risk Factors
    Language Portuguese
    Publishing date 2018-04-21
    Publishing country Spain
    Document type Journal Article ; Comment
    ZDB-ID 2646972-8
    ISSN 2174-2049 ; 2174-2049
    ISSN (online) 2174-2049
    ISSN 2174-2049
    DOI 10.1016/j.repc.2018.03.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Gender differences in the pathway of childhood trauma, impulsivity and adult eating behaviour: a cross-sectional study.

    Machado, Antônio Bonfada Collares / Teruya, Katia Irie / Friedman, Rogério / Weydmann, Gibson Juliano / Remor, Eduardo / Bizarro, Lisiane

    Journal of child and adolescent mental health

    2024  , Page(s) 1–13

    Abstract: Objective: ...

    Abstract Objective:
    Language English
    Publishing date 2024-04-18
    Publishing country South Africa
    Document type Journal Article
    ZDB-ID 2434930-6
    ISSN 1728-0591 ; 1728-0583
    ISSN (online) 1728-0591
    ISSN 1728-0583
    DOI 10.2989/17280583.2023.2293904
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Editorial: Vaginal dysbiosis and biofilms.

    Machado, António / Foschi, Claudio / Marangoni, Antonella

    Frontiers in cellular and infection microbiology

    2022  Volume 12, Page(s) 976057

    MeSH term(s) Biofilms ; Dysbiosis ; Female ; Humans ; Vagina ; Vaginosis, Bacterial
    Language English
    Publishing date 2022-08-09
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2619676-1
    ISSN 2235-2988 ; 2235-2988
    ISSN (online) 2235-2988
    ISSN 2235-2988
    DOI 10.3389/fcimb.2022.976057
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Improved Hypericin solubility via β-cyclodextrin complexation: Photochemical and theoretical study for PDT applications.

    Gusmão, Luiza Araújo / Machado, Antonio Eduardo H / Perussi, Janice Rodrigues

    Photodiagnosis and photodynamic therapy

    2022  Volume 40, Page(s) 103073

    Abstract: Hypericin (HY) is a lipophilic photosensitizer (PS) extensively employed for photodynamic therapy (PDT), presenting high absorption in the visible region, chemical and photostability, as well as a good triplet quantum yield. Supramolecular complexation ... ...

    Abstract Hypericin (HY) is a lipophilic photosensitizer (PS) extensively employed for photodynamic therapy (PDT), presenting high absorption in the visible region, chemical and photostability, as well as a good triplet quantum yield. Supramolecular complexation of photosensitizers into cyclodextrins (CD) is promising to improve their poor solubility, compromising their bioavailability and upcoming applications in PDT. This research produced an inclusion complex between HY and β-CD through the co-solvent method. HY became soluble after inclusion into β-CD cavities, besides retaining its fluorescent and singlet oxygen quantum yields (ϕ
    Language English
    Publishing date 2022-08-20
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2149918-4
    ISSN 1873-1597 ; 1572-1000
    ISSN (online) 1873-1597
    ISSN 1572-1000
    DOI 10.1016/j.pdpdt.2022.103073
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Cinnamomum

    Fernandez-Soto, Paulina / Celi, Diana / Tejera, Eduardo / Alvarez-Suarez, José Miguel / Machado, António

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 2

    Abstract: Horchata, a herbal infusion drink from Ecuador containing a mixture of medicinal plants, has been reported to exhibit anti-inflammatory, analgesic, diuretic, and antioxidant activity. The antibacterial activity of each of the plants contained in the ... ...

    Abstract Horchata, a herbal infusion drink from Ecuador containing a mixture of medicinal plants, has been reported to exhibit anti-inflammatory, analgesic, diuretic, and antioxidant activity. The antibacterial activity of each of the plants contained in the horchata mixture has not been fully evaluated. Thus, in this study, we analysed the antibacterial activity of 21 plants used in horchata, collected from the Ecuadorian Andes region, against bacterial strains of clinical importance. The methanolic extract of
    MeSH term(s) Staphylococcus aureus ; Pelargonium ; Cinnamomum/chemistry ; Methicillin-Resistant Staphylococcus aureus ; Plant Extracts/pharmacology ; Plant Extracts/chemistry ; Tandem Mass Spectrometry ; Gas Chromatography-Mass Spectrometry ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry ; Microbial Sensitivity Tests ; Tannins
    Chemical Substances Plant Extracts ; Anti-Bacterial Agents ; Tannins
    Language English
    Publishing date 2023-01-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28020693
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.MO 81: Show issues

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  8. Article ; Online: Electrocatalytic properties of a novel ruthenium(II) terpyridine-based complex towards CO

    Faustino, Leandro A / Machado, Antonio E H / Maia, Pedro I S / Concepcion, Javier J / Patrocinio, Antonio Otavio T

    Dalton transactions (Cambridge, England : 2003)

    2023  Volume 52, Issue 14, Page(s) 4442–4455

    Abstract: The electrocatalytic properties of Ru complexes are of great technological interest given their potential application in reactions such water splitting and ... ...

    Abstract The electrocatalytic properties of Ru complexes are of great technological interest given their potential application in reactions such water splitting and CO
    Language English
    Publishing date 2023-04-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472887-4
    ISSN 1477-9234 ; 1364-5447 ; 0300-9246 ; 1477-9226
    ISSN (online) 1477-9234 ; 1364-5447
    ISSN 0300-9246 ; 1477-9226
    DOI 10.1039/d3dt00121k
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Genetic legacies of mega-landslides: Cycles of isolation and contact across flank collapses in an oceanic island.

    Noguerales, Víctor / Arjona, Yurena / García-Olivares, Víctor / Machado, Antonio / López, Heriberto / Patiño, Jairo / Emerson, Brent C

    Molecular ecology

    2024  Volume 33, Issue 9, Page(s) e17341

    Abstract: Catastrophic flank collapses are recognized as important drivers of insular biodiversity dynamics, through the disruption of species ranges and subsequent allopatric divergence. However, little empirical data supports this conjecture, with their ... ...

    Abstract Catastrophic flank collapses are recognized as important drivers of insular biodiversity dynamics, through the disruption of species ranges and subsequent allopatric divergence. However, little empirical data supports this conjecture, with their evolutionary consequences remaining poorly understood. Using genome-wide data within a population genomics and phylogenomics framework, we evaluate how mega-landslides have impacted evolutionary and demographic history within a species complex of weevils (Curculionidae) within the Canary Island of Tenerife. We reveal a complex genomic landscape, within which individuals of single ancestry were sampled in areas characterized by long-term geological stability, relative to the timing of flank collapses. In contrast, individuals of admixed ancestry were almost exclusively sampled within the boundaries of flank collapses. Estimated divergence times among ancestral populations aligned with the timings of mega-landslide events. Our results provide first evidence for a cyclical dynamic of range fragmentation and secondary contact across flank collapse landscapes, with support for a model where this dynamic is mediated by Quaternary climate oscillations. The context within which we reveal climate and topography to interact cyclically through time to shape the geographic structure of genetic variation, together with related recent work, highlights the importance of topoclimatic phenomena as an agent of diversification within insular invertebrates.
    MeSH term(s) Animals ; Genetics, Population ; Islands ; Phylogeny ; Weevils/genetics ; Weevils/classification ; Biodiversity
    Language English
    Publishing date 2024-04-04
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1126687-9
    ISSN 1365-294X ; 0962-1083
    ISSN (online) 1365-294X
    ISSN 0962-1083
    DOI 10.1111/mec.17341
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 2005/723: Show issues

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  10. Article ; Online: Proton pump inhibitors and the risk of severe adverse events - A cardiovascular bombshell?

    Cunha, Nelson / Machado, António Pedro

    Revista portuguesa de cardiologia

    2018  Volume 37, Issue 10, Page(s) 859–863

    Abstract: Proton pump inhibitors are currently one of the most prescribed pharmacological classes in developed countries, given their effectiveness and safety profile, which has until now been considered favorable. However, in recent years, several papers have ... ...

    Title translation Inibidores da bomba de protões e o risco de eventos adversos graves – uma bomba cardiovascular?
    Abstract Proton pump inhibitors are currently one of the most prescribed pharmacological classes in developed countries, given their effectiveness and safety profile, which has until now been considered favorable. However, in recent years, several papers have been published that associate prolonged use of these drugs with a wide range of adverse effects, posing doubts about their safety. Among the adverse effects described is an increased risk of cardiovascular events. This relationship was first described in subjects after acute coronary syndrome due to the interference of proton pump inhibitors in the cytochrome P450 2C19 and the conversion of clopidogrel to its active metabolite. More recent studies have also reported this relationship with the use of antiplatelet agents that do not depend on cytochrome P450 2C19 activation. The proposed mechanism is inhibition of dimethylarginine dimethylaminohydrolase, a physiological inhibitor of asymmetric dimethylarginine, which increases plasma concentrations of the latter enzyme, leading to lower levels of nitric oxide. By reviewing in this article the relationship between the use of proton pump inhibitors and increased risk of cardiovascular and cerebrovascular events, the authors aim to alert the medical community to the potentially harmful effects of these drugs, and recommend the setting of a moratorium on their prolonged use.
    MeSH term(s) Humans ; Myocardial Ischemia/chemically induced ; Myocardial Ischemia/epidemiology ; Myocardial Ischemia/mortality ; Proton Pump Inhibitors/adverse effects ; Risk Factors
    Chemical Substances Proton Pump Inhibitors
    Language Portuguese
    Publishing date 2018-05-24
    Publishing country Spain
    Document type Journal Article ; Review
    ZDB-ID 2646972-8
    ISSN 2174-2049 ; 2174-2049
    ISSN (online) 2174-2049
    ISSN 2174-2049
    DOI 10.1016/j.repc.2017.10.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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