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  1. Article ; Online: Mindful eating questionnaire: Validation and reliability in Brazilian adults with type 2 diabetes mellitus.

    Rodrigues, Danielle Aparecida Caetano / Marcadenti, Aline / Machado, Rachel H V / Bersch-Ferreira, Angela C / Gherardi-Donato, Edilaine C S / Quinhoneiro, Driele / Almeida, Jussara Carnevale de / Souza, Viviane Sahade / Souza, Simone Raimondi de / Busnello, Fernanda Michielin / Ferreira, Daniela Corrêa / Bressan, Josefina / Figueiredo, Mariah Oliveira Abreu de / Reis, Nídia Marinho / Consoli, Marcella Lobato Dias / Ferreira, Lívia Garcia

    Appetite

    2024  Volume 195, Page(s) 107228

    Abstract: Objective: The objective was to evaluate the psychometric properties of the Mindful Eating Questionnaire (MEQ) in Brazilian subjects with type 2 diabetes mellitus (T2DM) and validate a Brazilian version of the MEQ for adults with T2DM (MEQ-DM).: ... ...

    Abstract Objective: The objective was to evaluate the psychometric properties of the Mindful Eating Questionnaire (MEQ) in Brazilian subjects with type 2 diabetes mellitus (T2DM) and validate a Brazilian version of the MEQ for adults with T2DM (MEQ-DM).
    Methodology: Baseline data from the multicentre Nutritional Strategy for Glycaemic Control in Patients with Type 2 Diabetes Mellitus (NUGLIC) trial were used. Construct validity was assessed using exploratory factor analysis (EFA). The root mean square error of approximation (RMSEA), comparative fit index (CFI) and Tucker‒Lewis index (TLI) fit indices indicated the adequacy of the model. The reliability of the questionnaire was evaluated considering the different factor loadings. Criterion validity was tested by correlating the MEQ-DM with sociodemographic variables, body mass index (BMI) and physical activity levels.
    Results: A total of 370 participants were included, who were mostly female (60.8 %) and had a median age of 61 (54-67) years. The EFA results supported the two-factor structure of the 25-item MEQ-DM: disinhibition and awareness. The results of the fit indices (RMSEA = 0.04; CFI = 0.95 and TLI = 0.94) and composite reliability (disinhibition = 0.84 and awareness = 0.81) were consistent. The criterion validity analysis indicated a significant association between MEQ-DM scores and age, sex, civil status, education level, BMI and physical activity (p < 0.05).
    Conclusion: When explored with Brazilian adults with T2DM, the MEQ-DM presented a factorial model with two dimensions: disinhibition and awareness. This model must be confirmed in future studies with Brazilians with T2DM.
    MeSH term(s) Aged ; Female ; Humans ; Male ; Middle Aged ; Brazil ; Diabetes Mellitus, Type 2 ; Psychometrics ; Reproducibility of Results ; South American People ; Surveys and Questionnaires ; Mindfulness ; Eating/psychology
    Language English
    Publishing date 2024-01-24
    Publishing country England
    Document type Journal Article ; Validation Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 1461347-5
    ISSN 1095-8304 ; 0195-6663
    ISSN (online) 1095-8304
    ISSN 0195-6663
    DOI 10.1016/j.appet.2024.107228
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Randomized Trial of Effect of Bariatric Surgery on Blood Pressure After 5 Years.

    Schiavon, Carlos A / Cavalcanti, Alexandre B / Oliveira, Juliana D / Machado, Rachel H V / Santucci, Eliana V / Santos, Renato N / Oliveira, Julia S / Damiani, Lucas P / Junqueira, Débora / Halpern, Helio / Monteiro, Frederico de L J / Noujaim, Patricia M / Cohen, Ricardo V / de Sousa, Marcio G / Bortolotto, Luiz A / Berwanger, Otavio / Drager, Luciano F

    Journal of the American College of Cardiology

    2023  Volume 83, Issue 6, Page(s) 637–648

    Abstract: Background: Obesity represents a major obstacle for controlling hypertension, the leading risk factor for cardiovascular mortality.: Objectives: The purpose of this study was to determine the long-term effects of bariatric surgery on hypertension ... ...

    Abstract Background: Obesity represents a major obstacle for controlling hypertension, the leading risk factor for cardiovascular mortality.
    Objectives: The purpose of this study was to determine the long-term effects of bariatric surgery on hypertension control and remission.
    Methods: We conducted a randomized clinical trial with subjects with obesity grade 1 or 2 plus hypertension using at least 2 medications. We excluded subjects with previous cardiovascular events and poorly controlled type 2 diabetes. Subjects were assigned to Roux-en-Y gastric bypass (RYGB) combined with medical therapy (MT) or MT alone. We reassessed the original primary outcome (reduction of at least 30% of the total antihypertensive medications while maintaining blood pressure levels <140/90 mm Hg) at 5 years. The main analysis followed the intention-to-treat principle.
    Results: A total of 100 subjects were included (76% women, age 43.8 ± 9.2 years, body mass index: 36.9 ± 2.7 kg/m
    Conclusions: Bariatric surgery represents an effective and durable strategy to control hypertension and related polypharmacy in subjects with obesity. (GAstric bypass to Treat obEse Patients With steAdy hYpertension [GATEWAY]; NCT01784848).
    MeSH term(s) Humans ; Female ; Adult ; Middle Aged ; Male ; Blood Pressure ; Antihypertensive Agents/therapeutic use ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/surgery ; Diabetes Mellitus, Type 2/drug therapy ; Bariatric Surgery ; Obesity/complications ; Obesity/surgery ; Gastric Bypass/adverse effects ; Gastric Bypass/methods ; Hypertension/drug therapy ; Hypertension/epidemiology ; Risk Factors ; Treatment Outcome ; Obesity, Morbid/surgery
    Chemical Substances Antihypertensive Agents
    Language English
    Publishing date 2023-12-28
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2023.11.032
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Maternal Feeding Practices among Children with Feeding Difficulties-Cross-sectional Study in a Brazilian Reference Center.

    Machado, Rachel H V / Tosatti, Abykeyla M / Malzyner, Gabriela / Maximino, Priscilla / Ramos, Cláudia C / Bozzini, Ana Beatriz / Ribeiro, Letícia / Fisberg, Mauro

    Frontiers in pediatrics

    2018  Volume 5, Page(s) 286

    Abstract: Background: Given the positive influence of responsive caregiving on dietary habits in childhood, to raise awareness of caregivers regarding their behavior is crucial in multidisciplinary care on infant feeding.: Objectives: To identify the most ... ...

    Abstract Background: Given the positive influence of responsive caregiving on dietary habits in childhood, to raise awareness of caregivers regarding their behavior is crucial in multidisciplinary care on infant feeding.
    Objectives: To identify the most common responsive and non-responsive feeding practices in mothers of children with feeding complaints, as well as to seek associations between practices and caregivers' profile.
    Methods: Cross-sectional study with 77 children under 18 years old, with complaints of feeding difficulties. Data were collected during interviews with mothers: child age, gender, duration of exclusive breastfeeding, presence of organic disease, dynamics of bottle use, self-feeding practices and posture at meals, use of appropriate feeding equipment; basic information about the mothers (parity and level of education), caregiver feeding style, presence of coercive feeding, frequency and characteristics of family meals. Statistical analysis considered significance level at 5%.
    Results: The non-responsive profile predominated among mothers (76.2%, with the Authoritarian style being the most prevalent-39.7%). The responsive profile was characterized by absence of coercive feeding, stimulation of self-feeding practices, use of appropriate feeding equipment and meal environment, with interaction at meals. Non-responsive profile consisted of both inadequate environment and posture at meals, use of distraction and coercive feeding, lack of shared meals, and disregard for children's hunger signals. Only the habit of sharing meals with children was associated with mothers' profile, and considered a protection factor against non-responsive care (OR 0.23; 95% CI 0.06-0.88). Both Authoritarian (
    Conclusion: Results highlight the need for educational interventions focused on caregivers' behaviors.
    Language English
    Publishing date 2018-01-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711999-3
    ISSN 2296-2360
    ISSN 2296-2360
    DOI 10.3389/fped.2017.00286
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Delayed Development of Feeding Skills in Children with Feeding Difficulties-Cross-sectional Study in a Brazilian Reference Center.

    Ramos, Cláudia C / Maximino, Priscila / Machado, Rachel H V / Bozzini, Ana Beatriz / Ribeiro, Letícia W / Fisberg, Mauro

    Frontiers in pediatrics

    2017  Volume 5, Page(s) 229

    Abstract: Background: Delays in gross motor development, sensory processing issues, and organic and behavioral problems are known to interfere in the development of feeding skills (FS); and-therefore-in the success of the process of feeding a child. Children with ...

    Abstract Background: Delays in gross motor development, sensory processing issues, and organic and behavioral problems are known to interfere in the development of feeding skills (FS); and-therefore-in the success of the process of feeding a child. Children with feeding difficulties (FD) commonly present inadequacy of FS.
    Objectives: Assessment of five FS in Brazilian children with FD, and search of associations with types of FD.
    Methods: Cross-sectional study with 70 children below 10 years old. Data were obtained from medical records: age, gender, age at texture transitions, feeding phase (breastfeeding, weaning to solids or full solids) at first complaint; characteristics of the meal (duration, environment, and shared meals with adults), self-feeding practices, use of feeding equipment and bottle, mouthing, feeding position and FD diagnosis. Skills were categorized according to standards for age. Chi-Square, Anova Test (or non-parametric equivalent) and Multinomial logistic regression tests were used, with a significance level of 5%.
    Results: There was no difference in FS (
    Conclusion: FS development or number of FS inadequateness did not vary according to FD diagnosis. Identification of these inadequacies could help the discussion for multi-professional treatment of patients with FD.
    Language English
    Publishing date 2017-10-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711999-3
    ISSN 2296-2360
    ISSN 2296-2360
    DOI 10.3389/fped.2017.00229
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Effectiveness of a two-component nutritional strategy for blood pressure control in individuals with hypertension users of a public health system: a randomized controlled clinical trial.

    Bersch-Ferreira, Angela C / Machado, Rachel H V / de Oliveira, Júlia S / Santos, Renato H N / da Silva, Lucas R / Mota, Luis G S / Pagano, Raira / Sady, Erica R R / Miyada, Débora H K / Valeis, Nanci / Martins, Pedro N / de Almeida, Jussara C / Marchioni, Dirce M L / Lara, Enilda M S / Gherardi-Donato, Edilaine C S / Quinhoneiro, Driele / Carvalho, Ana Paula P F / Machado, Malaine M A / Gedda, Lana P F /
    Ferro, Camila M B / Carvalho, Ana Clara M S / Feoli, Ana Maria P / Walker, Marthina S / Pinto, Sônia L / Silva, Kellen C / Bruscato, Neide M / Moriguchi, Emilio H / Penafort, Andreza M / Santiago, Rafaelle A / Osório, Denise R D / Rower, Helena B / Barbosa, Marina R / Silva, Joao Gabriel S T da / Weber, Bernardete / Cavalcanti, Alexandre B / Marcadenti, Aline

    Journal of hypertension

    2024  

    Abstract: Objective: To evaluate the effectiveness of a nutritional strategy based on two components and adapted for the public health system on blood pressure, cardiometabolic features, self-care, qualify of life and diet quality in individuals with hypertension. ...

    Abstract Objective: To evaluate the effectiveness of a nutritional strategy based on two components and adapted for the public health system on blood pressure, cardiometabolic features, self-care, qualify of life and diet quality in individuals with hypertension.
    Methods: NUPRESS was an open-label, parallel-group, superiority randomized controlled clinical trial in which participants at least 21 years with hypertension and poorly controlled blood pressure were randomly assigned (1 : 1 allocation ratio) to either an individualized dietary prescription according to nutritional guidelines (control group, n = 205); or a two-component nutrition strategy, including a goal-directed nutritional counseling and mindfulness techniques (NUPRESS [intervention] group, n = 205). Primary outcomes were SBP (mmHg) after 24 weeks of follow up and blood pressure control, defined as either having SBP more than 140 mmHg at baseline and achieving 140 mmHg or less after follow-up or having SBP 140 mmHg or less at baseline and reducing the frequency of antihypertensive drugs in use after follow-up.
    Results: In total, 410 participants were randomized and submitted to an intention-to-treat analysis regarding primary outcomes. Both groups decreased blood pressure, but after adjusting for baseline values, there was no significant difference between them on SBP [intervention-control difference: -0.03 (-3.01; 2.94); P = 0.98] nor blood pressure control [odds ratio 1.27 (0.82; 1.97); P = 0.28]. No differences between groups were also detected regarding secondary and tertiary outcomes.
    Conclusion: There was no difference between a two-component nutritional strategy and an established dietary intervention on blood pressure in participants with hypertension.
    Language English
    Publishing date 2024-02-26
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 605532-1
    ISSN 1473-5598 ; 0263-6352 ; 0952-1178
    ISSN (online) 1473-5598
    ISSN 0263-6352 ; 0952-1178
    DOI 10.1097/HJH.0000000000003703
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Vitamin profile of pregnant women living with HIV/AIDS

    Machado, Rachel H.V / Bonafe, Simone / Castelo, Adauto / Patin, Rose V

    e-SPEN, the European e-journal of clinical nutrition and metabolism. 2013 June, v. 8, no. 3

    2013  

    Abstract: BACKGROUND & AIMS: Maternal adequate micronutrient storage contributes to reducing morbidity and mortality of their children during the first two years of life. This study aimed at identifying hypovitaminosises among Brazilian HIV infected pregnant women ...

    Abstract BACKGROUND & AIMS: Maternal adequate micronutrient storage contributes to reducing morbidity and mortality of their children during the first two years of life. This study aimed at identifying hypovitaminosises among Brazilian HIV infected pregnant women and investigating their association with nutritional status, CD4⁺ cell counts, viral load and HAART use. METHODS: Cross-sectional study with 49 HIV infected pregnant women. Inclusion criteria followed: (1) HIV infection laboratory confirmation (HIV and HIV RNA); (2) Confirmed pregnancy, (3) Age above 14 years old; (4) Written consent. Exclusion criteria consisted of at least one of the following: (1) Use of any nutritional/multivitamin supplement (except iron or folinic acid); (2) Presence of nutritional counseling during the current pregnancy; (3) Presence of acute phase opportunistic diseases associated with HIV infection. Patients were evaluated according to anthropometric (gestational BMI, based on the curve of weight gain corrected for gestational age) and laboratory parameters (analysis of vitamin A, E, C, D, B6 and B12, CD4⁺ cell count, viral load, lipid profile, homocysteine and C-reactive protein). Blood samples were collected in 5 mL dry tubes with separating gel, after 12 h fasting. Vitamin profile was measured by HPLC. Results were classified according to abnormal ranges proposed for pregnant women. RESULTS: Low gestational weight was higher in women with CD4⁺ <200 cells/mm³ [OR = 12.5; 95% CI 2,00,77,89; p = 0.007]. Prevalence of abnormal serum concentrations was 38.8% for vitamin D, 14.3% for vitamin A, 22.4% for vitamin E, 12.2% for vitamin C, 53.2% for vitamin B6 and 32.6% for vitamin B12. C-reactive protein was associated with vitamin E [OR = 0.23, 95% CI 0.053, 1.01, p = 0.03] and A [OR = 0.15, 95% CI 0.028, 0.84, p = 0.03]. Homocysteine was not associated with lower vitamin concentrations. Women with optimal B12 levels were 4.3 times more likely to have CD4⁺ >200 cells/mm³ [OR = 0.23, 0.58 to 0.905, 95% CI, p = 0.03]. HIV viral load has not been significantly associated with vitamin concentrations. CONCLUSIONS: There was high prevalence of abnormal concentrations of vitamin A, D, B6 and B12. Nutritional status was associated with CD4⁺ cell count and vitamins were associated with immune function and inflammatory markers. There is need for more studies on this matter in Brazil. Vitamin serum levels should be monitored in these patients during prenatal care, and results underscore the importance of early nutritional intervention to ensure favorable pregnancy and birth outcomes, specially regarding the vitamin profile described here.
    Keywords C-reactive protein ; RNA ; ascorbic acid ; blood serum ; body mass index ; children ; cross-sectional studies ; diet counseling ; fasting ; gels ; gestational age ; high performance liquid chromatography ; homocysteine ; iron ; morbidity ; mortality ; nutritional intervention ; nutritional status ; patients ; pregnancy ; pregnant women ; prenatal care ; pyridoxine ; viral load ; vitamin A ; vitamin B12 ; vitamin D ; vitamin E ; weight gain ; Brazil
    Language English
    Dates of publication 2013-06
    Size p. e108-e112.
    Publishing place Elsevier Ltd
    Document type Article
    ISSN 2212-8263
    DOI 10.1016/j.clnme.2013.03.002
    Database NAL-Catalogue (AGRICOLA)

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  7. Article: Vitamin profile of pregnant women living with HIV/AIDS

    Machado, Rachel H.V. / Bonafe, Simone / Castelo, Adauto / Patin, Rose V.

    e-SPEN, the European e-journal of clinical nutrition and metabolism

    Volume v. 8,, Issue no. 3

    Abstract: BACKGROUND & AIMS: Maternal adequate micronutrient storage contributes to reducing morbidity and mortality of their children during the first two years of life. This study aimed at identifying hypovitaminosises among Brazilian HIV infected pregnant women ...

    Abstract BACKGROUND & AIMS: Maternal adequate micronutrient storage contributes to reducing morbidity and mortality of their children during the first two years of life. This study aimed at identifying hypovitaminosises among Brazilian HIV infected pregnant women and investigating their association with nutritional status, CD4⁺ cell counts, viral load and HAART use. METHODS: Cross-sectional study with 49 HIV infected pregnant women. Inclusion criteria followed: (1) HIV infection laboratory confirmation (HIV and HIV RNA); (2) Confirmed pregnancy, (3) Age above 14 years old; (4) Written consent. Exclusion criteria consisted of at least one of the following: (1) Use of any nutritional/multivitamin supplement (except iron or folinic acid); (2) Presence of nutritional counseling during the current pregnancy; (3) Presence of acute phase opportunistic diseases associated with HIV infection. Patients were evaluated according to anthropometric (gestational BMI, based on the curve of weight gain corrected for gestational age) and laboratory parameters (analysis of vitamin A, E, C, D, B6 and B12, CD4⁺ cell count, viral load, lipid profile, homocysteine and C-reactive protein). Blood samples were collected in 5 mL dry tubes with separating gel, after 12 h fasting. Vitamin profile was measured by HPLC. Results were classified according to abnormal ranges proposed for pregnant women. RESULTS: Low gestational weight was higher in women with CD4⁺ <200 cells/mm³ [OR = 12.5; 95% CI 2,00,77,89; p = 0.007]. Prevalence of abnormal serum concentrations was 38.8% for vitamin D, 14.3% for vitamin A, 22.4% for vitamin E, 12.2% for vitamin C, 53.2% for vitamin B6 and 32.6% for vitamin B12. C-reactive protein was associated with vitamin E [OR = 0.23, 95% CI 0.053, 1.01, p = 0.03] and A [OR = 0.15, 95% CI 0.028, 0.84, p = 0.03]. Homocysteine was not associated with lower vitamin concentrations. Women with optimal B12 levels were 4.3 times more likely to have CD4⁺ >200 cells/mm³ [OR = 0.23, 0.58 to 0.905, 95% CI, p = 0.03]. HIV viral load has not been significantly associated with vitamin concentrations. CONCLUSIONS: There was high prevalence of abnormal concentrations of vitamin A, D, B6 and B12. Nutritional status was associated with CD4⁺ cell count and vitamins were associated with immune function and inflammatory markers. There is need for more studies on this matter in Brazil. Vitamin serum levels should be monitored in these patients during prenatal care, and results underscore the importance of early nutritional intervention to ensure favorable pregnancy and birth outcomes, specially regarding the vitamin profile described here.
    Keywords blood serum ; ascorbic acid ; pregnant women ; cross-sectional studies ; children ; body mass index ; gels ; iron ; patients ; morbidity ; nutritional intervention ; homocysteine ; gestational age ; prenatal care ; fasting ; diet counseling ; RNA ; pregnancy ; mortality ; vitamin A ; vitamin B12 ; weight gain ; vitamin D ; vitamin E ; high performance liquid chromatography ; pyridoxine ; viral load ; C-reactive protein ; nutritional status
    Language English
    Document type Article
    ISSN 2212-8263
    Database AGRIS - International Information System for the Agricultural Sciences and Technology

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