Article ; Online: Unraveling the role of the microbiome in chronic rhinosinusitis.
The Journal of allergy and clinical immunology
2022 Volume 149, Issue 5, Page(s) 1513–1521
Abstract: Chronic rhinosinusitis (CRS) is a complex, heterogenous condition that is likely associated with infectious and inflammatory causative factors. Renewed interest in the role that microbes play in this condition has stemmed from advancements in microbe ... ...
Abstract | Chronic rhinosinusitis (CRS) is a complex, heterogenous condition that is likely associated with infectious and inflammatory causative factors. Renewed interest in the role that microbes play in this condition has stemmed from advancements in microbe identification and parallel research implicating the microbiome as having a role in other chronic inflammatory conditions. This clinical commentary provides a review of the current literature relevant to chronic rhinosinusitis. Particular focus is placed on factors specific to investigation of the sinonasal microbiome, evidence for the role of dysbiosis in the disease state, and influences that may affect the microbiome. Possible mechanisms of disease and therapeutic implications through microbial manipulation are also reviewed, as are deficiencies and limitations of the current body of research. |
---|---|
MeSH term(s) | Chronic Disease ; Dysbiosis ; Humans ; Microbiota ; Rhinitis/drug therapy ; Sinusitis/drug therapy |
Language | English |
Publishing date | 2022-03-14 |
Publishing country | United States |
Document type | Journal Article ; Review ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't |
ZDB-ID | 121011-7 |
ISSN | 1097-6825 ; 1085-8725 ; 0091-6749 |
ISSN (online) | 1097-6825 ; 1085-8725 |
ISSN | 0091-6749 |
DOI | 10.1016/j.jaci.2022.02.022 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
Full text online
More links
Kategorien
In stock of ZB MED Cologne/Königswinter
Uh III Zs.92: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.