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  1. AU="Magami, Shunsuke"
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  1. Article ; Online: A Single-Center Experience of Mechanical Thrombectomy for Cancer-Associated Ischemic Stroke.

    Magami, Shunsuke / Yoshida, Kouhei / Nakao, Yasuaki / Oishi, Hidenori / Yamamoto, Takuji

    Journal of neuroendovascular therapy

    2024  Volume 18, Issue 2, Page(s) 37–46

    Abstract: Objectives: Cancer-associated ischemic stroke tends to extend over multiple vascular territories and develops under poor general conditions. Owing to the rarity of such cases and poor prognoses, no comprehensive studies on mechanical thrombectomy for ... ...

    Abstract Objectives: Cancer-associated ischemic stroke tends to extend over multiple vascular territories and develops under poor general conditions. Owing to the rarity of such cases and poor prognoses, no comprehensive studies on mechanical thrombectomy for cancer-associated ischemic stroke have been reported in Japan. The present study investigated the radiological and clinical characteristics of mechanical thrombectomy in patients with cancer-associated ischemic stroke at our institution.
    Methods: We retrospectively reviewed 108 patients who underwent mechanical thrombectomy for large cerebral artery occlusion between January 1, 2021, and October 31, 2022, at our institution. The characteristics of mechanical thrombectomy in the cancer-associated ischemic stroke group were compared with those in the control group.
    Results: Of the 108 patients (112 procedures), seven patients (eight procedures) with clinically diagnosed cancer-associated ischemic stroke underwent mechanical thrombectomy. Of the eight procedures, six were performed during hospitalization. In contrast, only 10 of 104 procedures were performed in the control group. The in-hospital onset rate was higher in the cancer-associated ischemic stroke group (75.0%) compared to that in the controls (9.6%);
    Conclusion: Cancer-associated ischemic stroke tends to occur during hospitalization. Coagulation disorders associated with cancer, especially adenocarcinoma, may be related to the formation of thrombi with fibrinoplatelet-dominant components, leading to ischemic stroke. The procedural time for mechanical thrombectomy in cancer-associated ischemic stroke tends to be longer.
    Language English
    Publishing date 2024-01-25
    Publishing country Japan
    Document type Journal Article
    ISSN 2186-2494
    ISSN (online) 2186-2494
    DOI 10.5797/jnet.oa.2023-0067
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Cerebrospinal fluid rhinorrhea with meningoencephalocele related to Sternberg's canal: A report of two cases.

    Adachi, Satoshi / Ueno, Hideaki / Magami, Shunsuke / Fujita, Naohide / Nakajima, Shintaro / Ikemura, Ryogo / Ueki, Yasuhito / Takaki, Yuki / Murofushi, Keisuke / Nakao, Yasuaki / Yamamoto, Takuji

    Surgical neurology international

    2023  Volume 14, Page(s) 228

    Abstract: Background: Cerebrospinal fluid (CSF) rhinorrhea with meningoencephalocele (MEC) associated with Sternberg's canal is rare. We treated two such cases.: Case description: A 41-year-old man and a 35-year-old woman presented with CSF rhinorrhea and mild ...

    Abstract Background: Cerebrospinal fluid (CSF) rhinorrhea with meningoencephalocele (MEC) associated with Sternberg's canal is rare. We treated two such cases.
    Case description: A 41-year-old man and a 35-year-old woman presented with CSF rhinorrhea and mild headache worsening with standing posture. Head computed tomography showed a defect close to the foramen rotundum in the lateral wall of the left sphenoid sinus in both cases. Head magnetic resonance (MR) imaging and MR cisternography revealed that brain parenchyma had herniated into the lateral sphenoid sinus through the defect of the middle cranial fossa. The intradural and extradural spaces and bone defect were sealed with fascia and fat through both intradural and extradural approaches. The MEC was cut away to prevent infection. CSF rhinorrhea completely stopped after the surgery.
    Conclusion: Our cases were characterized by empty sella, thinning of the dorsum sellae, and large arteriovenous malformations that suggest chronic intracranial hypertension. The possibility of Sternberg's canal in patients with CSF rhinorrhea with chronic intracranial hypertension should be considered. The cranial approach has the advantages of lower infection risk and the ability to close the defect with multilayer plasty under direct vision. The transcranial approach is still safe if performed by a skillful neurosurgeon.
    Language English
    Publishing date 2023-06-30
    Publishing country United States
    Document type Case Reports
    ISSN 2229-5097
    ISSN 2229-5097
    DOI 10.25259/SNI_260_2023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The effects of A1/A2 astrocytes on oligodendrocyte linage cells against white matter injury under prolonged cerebral hypoperfusion.

    Miyamoto, Nobukazu / Magami, Shunsuke / Inaba, Toshiki / Ueno, Yuji / Hira, Kenichiro / Kijima, Chikage / Nakajima, Sho / Yamashiro, Kazuo / Urabe, Takao / Hattori, Nobutaka

    Glia

    2020  Volume 68, Issue 9, Page(s) 1910–1924

    Abstract: As oligodendrocyte precursor cells (OPCs) are vulnerable to ischemia, their differentiation to oligodendrocytes (OLG) is impaired in chronic cerebral hypoperfusion. Astrocyte-OLG interaction is important for white matter homeostasis. Recently, reactive ... ...

    Abstract As oligodendrocyte precursor cells (OPCs) are vulnerable to ischemia, their differentiation to oligodendrocytes (OLG) is impaired in chronic cerebral hypoperfusion. Astrocyte-OLG interaction is important for white matter homeostasis. Recently, reactive astrocytes were separated into two types, A1 (cytotoxic) and A2 (neurotrophic). However, their role in prolonged cerebral hypoperfusion remains unclear. We analyzed the effects of interaction between A1-A2 astrocytes and OPC-OLG under hypoperfusion, focusing on mitochondrial migration. As an in vivo model, chronic hypoperfusion model mice were created by bilateral common carotid artery stenosis (BCAS) using microcoils. As a matching in vitro study, rat primary cells were cocultured with a nonlethal concentration of CoCl
    MeSH term(s) Animals ; Astrocytes ; Brain Ischemia ; Carotid Stenosis ; Culture Media, Conditioned/pharmacology ; Disease Models, Animal ; Mice ; Mice, Inbred C57BL ; Oligodendroglia ; Rats ; White Matter
    Chemical Substances Culture Media, Conditioned
    Language English
    Publishing date 2020-02-28
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639414-0
    ISSN 1098-1136 ; 0894-1491
    ISSN (online) 1098-1136
    ISSN 0894-1491
    DOI 10.1002/glia.23814
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The Effects of Astrocyte and Oligodendrocyte Lineage Cell Interaction on White Matter Injury under Chronic Cerebral Hypoperfusion.

    Magami, Shunsuke / Miyamoto, Nobukazu / Ueno, Yuji / Hira, Kenichiro / Tanaka, Ryota / Yamashiro, Kazuo / Oishi, Hidenori / Arai, Hajime / Urabe, Takao / Hattori, Nobutaka

    Neuroscience

    2019  Volume 406, Page(s) 167–175

    Abstract: Oligodendrocytes (OLGs) differentiate from oligodendrocyte-precursor-cells (OPCs) for myelination in white matter. This differentiation is maintained by cell-cell interactions through trophic factors such as brain-derived-neurotrophic-factor (BDNF). ... ...

    Abstract Oligodendrocytes (OLGs) differentiate from oligodendrocyte-precursor-cells (OPCs) for myelination in white matter. This differentiation is maintained by cell-cell interactions through trophic factors such as brain-derived-neurotrophic-factor (BDNF). However, differentiation is impaired when white matter injury occurs in a chronic cerebral hypoperfusion model. Thus, we examined the effects of the interaction between astrocyte and oligodendrocyte lineage cells on myelination regarding the mechanism of impairment. A microcoil was applied to the bilateral common carotid arteries in male C57BL/6 mice as an in vivo cerebral chronic hypoperfusion model (BCAS model). A nonlethal concentration of CoCl2 was added to the primary cell culture from the postnatal rat cortex and incubated in vitro. White matter injury progressed in the BCAS model as myelin decreased. The numbers of OPCs and astrocytes increased after the operation, whereas that of OLGs decreased at day 28. BDNF continuously decreased until day 28. Differentiation was disrupted under the stressed conditions in the cell culture, but improved after administration of astrocyte-conditioned medium containing BDNF. Astrocytes with BDNF underwent differentiation, but differentiation was impaired under the stressed conditions due to the reduction of BDNF. We examined S100B regarding the mechanism of impairment. S100B is mainly expressed by mature astrocytes, and has neuroprotective and neurotoxic effects inside and outside of cells. GFAP-positive astrocytes increased in the corpus callosum in the BCAS model, whereas the number of mature astrocytes continued to decrease, resulting in reduced BDNF. The reduction in mature astrocytes due to the discharge of S100B in ischemic conditions caused the reduction in BDNF.
    MeSH term(s) Animals ; Astrocytes/metabolism ; Brain-Derived Neurotrophic Factor/metabolism ; Cell Lineage/physiology ; Cells, Cultured ; Cerebrovascular Circulation/physiology ; Male ; Mice ; Mice, Inbred C57BL ; Neocortex/blood supply ; Neocortex/metabolism ; Oligodendroglia/metabolism ; Rats ; S100 Calcium Binding Protein beta Subunit/metabolism ; White Matter/blood supply ; White Matter/injuries ; White Matter/metabolism
    Chemical Substances Bdnf protein, rat ; Brain-Derived Neurotrophic Factor ; S100 Calcium Binding Protein beta Subunit ; S100b protein, rat
    Language English
    Publishing date 2019-03-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 196739-3
    ISSN 1873-7544 ; 0306-4522
    ISSN (online) 1873-7544
    ISSN 0306-4522
    DOI 10.1016/j.neuroscience.2019.03.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Endovascular parent artery occlusion of proximal posterior cerebral artery aneurysms: a report of two cases.

    Oishi, Hidenori / Tanoue, Shunsuke / Teranishi, Kosuke / Hasegawa, Hiroshi / Nonaka, Senshu / Magami, Shunsuke / Yamamoto, Munetaka / Arai, Hajime

    Journal of neurointerventional surgery

    2016  Volume 8, Issue 6, Page(s) 591–593

    Abstract: We report two cases of proximal posterior cerebral artery (PCA) aneurysms treated with endovascular parent artery occlusion (PAO) with coils. In both cases, selective injection from the 4 F distal access catheter clearly showed the perforating arteries ... ...

    Abstract We report two cases of proximal posterior cerebral artery (PCA) aneurysms treated with endovascular parent artery occlusion (PAO) with coils. In both cases, selective injection from the 4 F distal access catheter clearly showed the perforating arteries arising from the PCA. Case No 1, a 49-year-old woman, was successfully treated with preservation of a paramedian artery. Case No 2, a 54-year-old woman, was treated in the same manner. The patient underwent extensive thalamic infarction after the procedure because of paramedian artery occlusion. Endovascular PAO with coils is feasible for proximal PCA aneurysms; however, preservation of perforating arteries arising from the PCA is mandatory.
    MeSH term(s) Brain Infarction/etiology ; Embolization, Therapeutic/adverse effects ; Endovascular Procedures ; Female ; Humans ; Intracranial Aneurysm/diagnostic imaging ; Intracranial Aneurysm/surgery ; Middle Aged ; Posterior Cerebral Artery/diagnostic imaging ; Posterior Cerebral Artery/surgery ; Thalamus/blood supply ; Thalamus/pathology
    Language English
    Publishing date 2016-06
    Publishing country England
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 2514982-9
    ISSN 1759-8486 ; 1759-8478
    ISSN (online) 1759-8486
    ISSN 1759-8478
    DOI 10.1136/neurintsurg-2015-011762
    Database MEDical Literature Analysis and Retrieval System OnLINE

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