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  1. Article ; Online: Synergistic Effect of

    Aly, Shaza H / Elissawy, Ahmed M / Mahmoud, Abdulla M A / El-Tokhy, Fatma Sa'eed / Mageed, Sherif S Abdel / Almahli, Hadia / Al-Rashood, Sara T / Binjubair, Faizah A / Hassab, Mahmoud A El / Eldehna, Wagdy M / Singab, Abd El-Nasser B

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 7

    Abstract: Glycyrrhiza ... ...

    Abstract Glycyrrhiza glabra
    MeSH term(s) Flavonoids/pharmacology ; Flavonoids/analysis ; Sophora japonica ; Molecular Docking Simulation ; Glycogen Synthase Kinase 3 ; Ointments ; Plant Extracts/pharmacology ; Plant Extracts/chemistry ; Glycyrrhiza/chemistry ; Wound Healing
    Chemical Substances Flavonoids ; Glycogen Synthase Kinase 3 (EC 2.7.11.26) ; Ointments ; Plant Extracts
    Language English
    Publishing date 2023-03-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28072994
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.MO 81: Show issues

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  2. Article ; Online: miRNAs orchestration of cardiovascular diseases - Particular emphasis on diagnosis, and progression.

    Elsakka, Elsayed G E / Abulsoud, Ahmed I / El-Mahdy, Hesham A / Ismail, Ahmed / Elballal, Mohammed S / Mageed, Sherif S Abdel / Khidr, Emad Gamil / Mohammed, Osama A / Sarhan, Omnia M / Elkhawaga, Samy Y / El-Husseiny, Ahmed A / Abdelmaksoud, Nourhan M / El-Demerdash, Aya A / Shahin, Reem K / Midan, Heba M / Elrebehy, Mahmoud A / Doghish, Ayman A / Doghish, Ahmed S

    Pathology, research and practice

    2023  Volume 248, Page(s) 154613

    Abstract: MicroRNAs (miRNAs; miRs) are small non-coding ribonucleic acids sequences vital in regulating gene expression. They are significant in many biological and pathological processes and are even detectable in various body fluids such as serum, plasma, and ... ...

    Abstract MicroRNAs (miRNAs; miRs) are small non-coding ribonucleic acids sequences vital in regulating gene expression. They are significant in many biological and pathological processes and are even detectable in various body fluids such as serum, plasma, and urine. Research has demonstrated that the irregularity of miRNA in multiplying cardiac cells is linked to developmental deformities in the heart's structure. It has also shown that miRNAs are crucial in diagnosing and progressing several cardiovascular diseases (CVDs). The review covers the function of miRNAs in the pathophysiology of CVD. Additionally, the review provides an overview of the potential role of miRNAs as disease-specific diagnostic and prognostic biomarkers for human CVD, as well as their biological implications in CVD.
    Language English
    Publishing date 2023-06-12
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 391889-0
    ISSN 1618-0631 ; 0344-0338
    ISSN (online) 1618-0631
    ISSN 0344-0338
    DOI 10.1016/j.prp.2023.154613
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ud III Zs.20: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: miRNAs orchestration of salivary gland cancer- Particular emphasis on diagnosis, progression, and drug resistance.

    El-Husseiny, Ahmed A / Abdelmaksoud, Nourhan M / Mageed, Sherif S Abdel / Salman, Aya / Zaki, Mohamed Bakr / El-Mahdy, Hesham A / Ismail, Ahmed / Abd-Elmawla, Mai A / El-Husseiny, Hussein M / Abulsoud, Ahmed I / Elshaer, Shereen Saeid / Elsakka, Elsayed G E / Fathi, Doaa / El-Dakroury, Walaa A / Doghish, Ahmed S

    Pathology, research and practice

    2023  Volume 248, Page(s) 154590

    Abstract: Cancer of the salivary glands is one of the five major types of head and neck cancer. Due to radioresistance and a strong propensity for metastasis, the survival rate for nonresectable malignant tumors is dismal. Hence, more research is needed on ... ...

    Abstract Cancer of the salivary glands is one of the five major types of head and neck cancer. Due to radioresistance and a strong propensity for metastasis, the survival rate for nonresectable malignant tumors is dismal. Hence, more research is needed on salivary cancer's pathophysiology, particularly at the molecular level. The microRNAs (miRNAs) are a type of noncoding RNA that controls as many as 30% of all genes that code for proteins at the posttranscriptional level. Signature miRNA expression profiles have been established in several cancer types, suggesting a role for miRNAs in the incidence and progression of human malignancies. Salivary cancer tissues were shown to have significantly aberrant levels of miRNAs compared to normal salivary gland tissues, supporting the hypothesis that miRNAs play a crucial role in the carcinogenesis of salivary gland cancer (SGC). Besides, several SGC research articles reported potential biomarkers and therapeutic targets for the miRNA-based treatment of this malignancy. In this review, we will explore the regulatory impact of miRNAs on the processes underlying the molecular pathology of SGC and provide an up-to-date summary of the literature on miRNAs that impacted this malignancy. We will eventually share information about their possible use as diagnostic, prognostic, and therapeutic biomarkers in SGC.
    MeSH term(s) Humans ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Salivary Gland Neoplasms/diagnosis ; Salivary Gland Neoplasms/genetics ; Salivary Gland Neoplasms/metabolism ; Salivary Glands/pathology ; Head and Neck Neoplasms/pathology ; Drug Resistance ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Gene Expression Regulation, Neoplastic/genetics
    Chemical Substances MicroRNAs ; Biomarkers, Tumor
    Language English
    Publishing date 2023-06-07
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 391889-0
    ISSN 1618-0631 ; 0344-0338
    ISSN (online) 1618-0631
    ISSN 0344-0338
    DOI 10.1016/j.prp.2023.154590
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ud III Zs.20: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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