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  1. Book: Hunter's tropical medicine and emerging infectious disease

    Magill, Alan J. / Hunter, George W.

    (ExpertConsult.com)

    2013  

    Title variant Tropical medicine and emerging infectious disease
    Author's details Alan J. Magill
    Series title ExpertConsult.com
    Keywords Tropical medicine ; Emerging infectious diseases
    Subject code 616.9883
    Language English
    Size XXIV, 1190 S. : Ill., graph. Darst., Kt., 29 cm
    Edition 9. ed.
    Publisher Saunders Elsevier
    Publishing place London u.a.
    Publishing country Great Britain
    Document type Book
    Note Previous ed.: 2000. - Includes Internet access
    Accompanying material Zugang zur Internetausgabe über Code
    HBZ-ID HT017480479
    ISBN 978-1-4160-4390-4 ; 1-4160-4390-X
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2009 A 8691 order for loan Magazin
    Zugang zur Internetausgabe über Code aus lizenzrechtlichen Gründen nicht verfügbar
    2012 A 6040 order for loan Magazin
    Zugang zur Internetausgabe über Code aus lizenzrechtlichen Gründen nicht verfügbar

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  2. Article ; Online: Primaquine for prophylaxis of malaria: has the CYP sailed?

    Deye, Gregory A / Magill, Alan J

    Journal of travel medicine

    2014  Volume 21, Issue 1, Page(s) 67–69

    MeSH term(s) Antimalarials/pharmacokinetics ; Antimalarials/therapeutic use ; Biotransformation ; Chemoprevention/methods ; Cytochrome P-450 Enzyme System/metabolism ; Drug Resistance/physiology ; Humans ; Isoenzymes ; Malaria/metabolism ; Malaria/prevention & control ; Post-Exposure Prophylaxis/methods ; Primaquine/pharmacokinetics ; Primaquine/therapeutic use ; Secondary Prevention ; Travel ; Treatment Outcome
    Chemical Substances Antimalarials ; Isoenzymes ; Cytochrome P-450 Enzyme System (9035-51-2) ; Primaquine (MVR3634GX1)
    Language English
    Publishing date 2014-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 1212504-0
    ISSN 1708-8305 ; 1195-1982
    ISSN (online) 1708-8305
    ISSN 1195-1982
    DOI 10.1111/jtm.12080
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  3. Article: Malaria: diagnosis and treatment of falciparum malaria in travelers during and after travel.

    Magill, Alan J

    Current infectious disease reports

    2006  Volume 8, Issue 1, Page(s) 35–42

    Abstract: Plasmodium falciparum is responsible for most of the mortality in travelers related to imported malaria. Problems that occur during travel include the inaccuracy of a microscopic diagnosis of malaria, both false positives and false negatives, when ill ... ...

    Abstract Plasmodium falciparum is responsible for most of the mortality in travelers related to imported malaria. Problems that occur during travel include the inaccuracy of a microscopic diagnosis of malaria, both false positives and false negatives, when ill travelers seek care while abroad. A false positive diagnosis can result in unnecessary parenteral injections that carry a risk of transmission of blood-borne pathogens, receipt of potentially dangerous drugs such as halofantrine, or receipt of fake, counterfeit drugs. Increased morbidity and mortality are associated with delays in diagnosis and initiation of prompt treatment for falciparum malaria. Availability of expert microscopy to confirm the diagnosis of malaria is limited. The presence of splenomegaly and thrombocytopenia are strongly associated with malaria and would justify empiric treatment. The availability of atovaquone-proguanil, a safe and well tolerated oral drug, should prompt a reconsideration of current treatment recommendations that discourage empiric treatment on clinical suspicion alone.
    Language English
    Publishing date 2006-01-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2019948-X
    ISSN 1534-3146 ; 1523-3847
    ISSN (online) 1534-3146
    ISSN 1523-3847
    DOI 10.1007/s11908-006-0033-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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  4. Book: Hunter's tropical medicine and emerging infectious diseases

    Magill, Alan J / Hunter, George W

    2013  

    Title variant Tropical medicine and emerging infectious diseases ; Tropical medicine and emerging infectious disease
    MeSH term(s) Tropical Medicine
    Language English
    Size xxiv, 1190 p. :, ill. (some col.), maps ;, 29 cm.
    Edition 9th ed. /
    Publisher Saunders
    Publishing place New York
    Document type Book
    Note Previous ed.: 2000.
    ISBN 9781416043904 ; 141604390X
    Database Catalogue of the US National Library of Medicine (NLM)

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  5. Book ; Online: Hunter's tropical medicine and emerging infectious diseases

    Hunter, George William / Magill, Alan J

    2013  

    Abstract: Hunter's Tropical Medicine and Emerging Infectious Disease is your comprehensive, go-to resource on the health conditions that arise in the tropics! From infectious diseases through environmental issues, poisoning and toxicology, animal injuries, and ... ...

    Title variant Tropical medicine and emerging infectious diseases
    Author's details Alan J. Magill ... [et al.]
    Abstract Hunter's Tropical Medicine and Emerging Infectious Disease is your comprehensive, go-to resource on the health conditions that arise in the tropics! From infectious diseases through environmental issues, poisoning and toxicology, animal injuries, and nutritional and micronutrient deficiencies, this medical reference book provides you with all the guidance you need to diagnose and manage even the most exotic health concerns. Stay at the forefront of this ever-changing field with Hunter's Tropical Medicine and Emerging Infectious Disease! Understand the common characteristics and methods of transmission for each disease, and learn all the applicable diagnosis, treatment, control, and prevention techniques.Get the information you need in the most organized way with infectious agents arranged by syndromes, as they typically present
    MeSH term(s) Tropical Medicine
    Keywords Emerging infectious diseases ; Tropical medicine
    Language English
    Size Online-Ressource (xxiv, 1190 p), ill. (some col.), maps
    Edition 9th ed
    Publisher Saunders/Elsevier
    Publishing place London ;New York
    Document type Book ; Online
    Note Includes Internet access ; Includes bibliographical references and index ; Previous ed.: 2000
    ISBN 141604390X ; 1455740438 ; 9781416043904 ; 9781455740437
    Database Former special subject collection: coastal and deep sea fishing

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  6. Book ; Online: Hunter's tropical medicine and emerging infectious diseases

    Hunter, George William / Magill, Alan J

    2013  

    Abstract: Hunter's Tropical Medicine and Emerging Infectious Disease is your comprehensive, go-to resource on the health conditions that arise in the tropics! From infectious diseases through environmental issues, poisoning and toxicology, animal injuries, and ... ...

    Title variant Tropical medicine and emerging infectious diseases
    Author's details Alan J. Magill ... [et al.]
    Abstract Hunter's Tropical Medicine and Emerging Infectious Disease is your comprehensive, go-to resource on the health conditions that arise in the tropics! From infectious diseases through environmental issues, poisoning and toxicology, animal injuries, and nutritional and micronutrient deficiencies, this medical reference book provides you with all the guidance you need to diagnose and manage even the most exotic health concerns. Stay at the forefront of this ever-changing field with Hunter's Tropical Medicine and Emerging Infectious Disease! Understand the common characteristics and methods of transmission for each disease, and learn all the applicable diagnosis, treatment, control, and prevention techniques.Get the information you need in the most organized way with infectious agents arranged by syndromes, as they typically present
    MeSH term(s) Tropical Medicine
    Keywords Emerging infectious diseases ; Tropical medicine
    Language English
    Size Online-Ressource (xxiv, 1190 p), ill. (some col.), maps
    Edition 9th ed
    Publisher Saunders/Elsevier
    Publishing place London ;New York
    Document type Book ; Online
    Note Includes Internet access ; Includes bibliographical references and index ; Previous ed.: 2000
    ISBN 141604390X ; 1455740438 ; 9781416043904 ; 9781455740437
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  7. Article: Cutaneous leishmaniasis in the returning traveler.

    Magill, Alan J

    Infectious disease clinics of North America

    2005  Volume 19, Issue 1, Page(s) 241–66, x–xi

    Abstract: Infection with protozoan parasites of the genus Leishmania leads to a wide variety of clinical disease syndromes called leishmaniasis, or more appropriately the leishmaniases. The three major clinical syndromes are cutaneous leishmaniasis, mucosal ... ...

    Abstract Infection with protozoan parasites of the genus Leishmania leads to a wide variety of clinical disease syndromes called leishmaniasis, or more appropriately the leishmaniases. The three major clinical syndromes are cutaneous leishmaniasis, mucosal leishmaniasis, and visceral leishmaniasis. All three of these syndromes have been documented in returning travelers. This article focuses on cutaneous leishmaniasis with some comment on mucosal leishmaniasis.
    MeSH term(s) Animals ; Antiprotozoal Agents/therapeutic use ; Humans ; Leishmania/classification ; Leishmaniasis, Cutaneous/diagnosis ; Leishmaniasis, Cutaneous/drug therapy ; Leishmaniasis, Cutaneous/epidemiology ; Leishmaniasis, Cutaneous/pathology ; Travel
    Chemical Substances Antiprotozoal Agents
    Language English
    Publishing date 2005-03
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1077676-x
    ISSN 1557-9824 ; 0891-5520
    ISSN (online) 1557-9824
    ISSN 0891-5520
    DOI 10.1016/j.idc.2004.11.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Se 1187: Show issues Location:
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  8. Article: The prevention of malaria.

    Magill, Alan J

    Primary care

    2003  Volume 29, Issue 4, Page(s) 815–42, v–vi

    Abstract: Long before the advent of modern chemoprophylaxis drugs, many practitioners successfully prevented the debilitating and fatal outcomes associated with infection by the Plasmodium parasites that cause malaria. Today, with effective insect repellents and ... ...

    Abstract Long before the advent of modern chemoprophylaxis drugs, many practitioners successfully prevented the debilitating and fatal outcomes associated with infection by the Plasmodium parasites that cause malaria. Today, with effective insect repellents and several excellent medications available for chemoprophylaxis, there has never been a better array of quality products to prevent mosquito bites and infection and to suppress parasites once in the blood stream; however, there are thousands of imported cases into nonendemic countries and scores of deaths and near-fatal outcomes every year in returning travelers, soldiers, immigrants, and refugees. In this article, the author focuses on practical uses of currently available prevention tools.
    MeSH term(s) Animals ; Anopheles ; Antimalarials/administration & dosage ; Bedding and Linens ; Chemoprevention ; Developing Countries ; Humans ; Insect Bites and Stings/prevention & control ; Insect Repellents ; Malaria/prevention & control ; Primary Health Care ; Primary Prevention/methods ; Protective Clothing ; Travel
    Chemical Substances Antimalarials ; Insect Repellents
    Language English
    Publishing date 2003-03-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 604005-6
    ISSN 1558-299X ; 0095-4543
    ISSN (online) 1558-299X
    ISSN 0095-4543
    DOI 10.1016/s0095-4543(02)00042-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1154: Show issues Location:
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  9. Article ; Online: Review: Malaria chemoprophylaxis for travelers to Latin America.

    Steinhardt, Laura C / Magill, Alan J / Arguin, Paul M

    The American journal of tropical medicine and hygiene

    2011  Volume 85, Issue 6, Page(s) 1015–1024

    Abstract: Because of recent declining malaria transmission in Latin America, some authorities have recommended against chemoprophylaxis for most travelers to this region. However, the predominant parasite species in Latin America, Plasmodium vivax, can form ... ...

    Abstract Because of recent declining malaria transmission in Latin America, some authorities have recommended against chemoprophylaxis for most travelers to this region. However, the predominant parasite species in Latin America, Plasmodium vivax, can form hypnozoites sequestered in the liver, causing malaria relapses. Additionally, new evidence shows the potential severity of vivax infections, warranting continued consideration of prophylaxis for travel to Latin America. Individualized travel risk assessments are recommended and should consider travel locations, type, length, and season, as well as probability of itinerary changes. Travel recommendations might include no precautions, mosquito avoidance only, or mosquito avoidance and chemoprophylaxis. There are a range of good options for chemoprophylaxis in Latin America, including atovaquone-proguanil, doxycycline, mefloquine, and--in selected areas--chloroquine. Primaquine should be strongly considered for nonpregnant, G6PD-nondeficient patients traveling to vivax-endemic areas of Latin America, and it has the added benefit of being the only drug to protect against malaria relapses.
    MeSH term(s) Antimalarials/administration & dosage ; Antimalarials/therapeutic use ; Atovaquone/therapeutic use ; Drug Combinations ; Drug Therapy, Combination ; Humans ; Latin America/epidemiology ; Malaria/epidemiology ; Malaria/parasitology ; Malaria/prevention & control ; Malaria, Vivax/epidemiology ; Malaria, Vivax/prevention & control ; Plasmodium vivax ; Primaquine/therapeutic use ; Proguanil/therapeutic use ; Travel
    Chemical Substances Antimalarials ; Drug Combinations ; atovaquone, proguanil drug combination ; Primaquine (MVR3634GX1) ; Proguanil (S61K3P7B2V) ; Atovaquone (Y883P1Z2LT)
    Language English
    Publishing date 2011-12-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2942-7
    ISSN 1476-1645 ; 0002-9637
    ISSN (online) 1476-1645
    ISSN 0002-9637
    DOI 10.4269/ajtmh.2011.11-0464
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Clinical development of new prophylactic antimalarial drugs after the 5th Amendment to the Declaration of Helsinki.

    Dow, Geoffrey S / Magill, Alan J / Ohrt, Colin

    Therapeutics and clinical risk management

    2009  Volume 4, Issue 4, Page(s) 803–819

    Abstract: Malaria is of continuing concern in nonimmune traveling populations. Traditionally, antimalarial drugs have been developed as agents for dual indications (treatment and prophylaxis). However, since 2000, when the 5th Amendment to the Declaration of ... ...

    Abstract Malaria is of continuing concern in nonimmune traveling populations. Traditionally, antimalarial drugs have been developed as agents for dual indications (treatment and prophylaxis). However, since 2000, when the 5th Amendment to the Declaration of Helsinki (DH2000) was adopted, development of new malaria prophylaxis drugs in this manner has ceased. As a consequence, there may not be any new drugs licensed for this indication in the foreseeable future. Major pharmaceutical companies have interpreted DH2000 to mean that the traditional development paradigm may be considered unethical because of doubt over the likelihood of benefit to endemic populations participating in clinical studies, the use of placebo, and the sustainability of post-trial access to study medications. In this article, we explore the basis of these concerns and suggest that the traditional development paradigm remains ethical under certain circumstances. We also consider alternative approaches that may be more attractive to sponsors as they either do not use placebo, or utilize populations in endemic countries who may unambiguously benefit. These approaches represent the way forward in the future, but are at present unproven in clinical practice, and face numerous regulatory, logistical and technical challenges. Consequently, in the short term, we argue that the traditional clinical development paradigm remains the most feasible approach and is ethical and consistent with the spirit of DH2000 under the appropriate circumstances.
    Language English
    Publishing date 2009-02-05
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2186560-7
    ISSN 1178-203X ; 1176-6336
    ISSN (online) 1178-203X
    ISSN 1176-6336
    DOI 10.2147/tcrm.s1025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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