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  1. AU="Mahajan, Aman"
  2. AU="Hao, Yanling"
  3. AU="Eing, Lorenz"
  4. AU="Geoffroy, Pierre A"
  5. AU="Chapuis, J"
  6. AU="Berta, László"
  7. AU="Barzilay, Regina"
  8. AU="Schmidt, Michael Rahbek"
  9. AU=Tack J
  10. AU="Oh, Hye Min"
  11. AU=Gaffen Sarah L AU=Gaffen Sarah L
  12. AU="Schmitt, Christine"
  13. AU="McKay, Jackie"
  14. AU="Bellissimo, Catherine A"
  15. AU="Desai, Urja"
  16. AU="Chini, Maria Giovanna"
  17. AU="Xiao, Difei"
  18. AU="Ryan, Chris"
  19. AU="Omar Bazighifan"
  20. AU="Corominas Galbany, Jordi"
  21. AU=Fox Norma E
  22. AU="Hamilton, Shelia M"
  23. AU="Nichols, J Wylie"
  24. AU="Pesce R."
  25. AU="Gambitta, P"
  26. AU="Imran, Aqeel"
  27. AU="Sharma, Yashoda"
  28. AU="Kosai, Jordyn"
  29. AU="Aroca Ferri, María"
  30. AU="Laba, Stephanie"
  31. AU="Kim, Ye-Sel"

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  1. Buch: Transplantation

    Mahajan, Aman

    (Anesthesiology clinics ; volume 35, number 3 (September 2017))

    2017  

    Verfasserangabe editors Aman Mahajan, Christopher Wray
    Serientitel Anesthesiology clinics ; volume 35, number 3 (September 2017)
    Überordnung
    Sprache Englisch
    Umfang xvi Seiten, Seite 366-553, Illustrationen
    Verlag Elsevier
    Erscheinungsort Philadelphia, Pennsylvania
    Erscheinungsland Vereinigte Staaten
    Dokumenttyp Buch
    HBZ-ID HT019470783
    ISBN 978-0-323-55266-0 ; 0-323-55266-8
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  2. Artikel ; Online: Innovations in Practices and Technologies That Will Shape Perioperative Medicine.

    Mahajan, Aman / Mythen, Monty Michael

    Anesthesia and analgesia

    2023  Band 136, Heft 4, Seite(n) 623–626

    Mesh-Begriff(e) Perioperative Medicine
    Sprache Englisch
    Erscheinungsdatum 2023-03-16
    Erscheinungsland United States
    Dokumenttyp Editorial ; Research Support, N.I.H., Extramural
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000006439
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 149: Hefte anzeigen

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  3. Artikel ; Online: In Response.

    Schnetz, Michael P / Mahajan, Aman

    Anesthesia and analgesia

    2023  Band 137, Heft 4, Seite(n) e38

    Sprache Englisch
    Erscheinungsdatum 2023-09-05
    Erscheinungsland United States
    Dokumenttyp Letter ; Comment
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000006631
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  4. Artikel ; Online: Development of Highly Sensitive and Humidity Independent Room Temeprature NO

    Gasso, Sahil / Mahajan, Aman

    ACS sensors

    2022  Band 7, Heft 8, Seite(n) 2454–2464

    Abstract: Room temperature gas sensors have been widely explored in gas sensor technology for real-time applications. However, humidity has found to affect the room temperature sensing and the sensor life, necessitating the development of novel sensing materials ... ...

    Abstract Room temperature gas sensors have been widely explored in gas sensor technology for real-time applications. However, humidity has found to affect the room temperature sensing and the sensor life, necessitating the development of novel sensing materials with high sensitivity and stability under humid conditions at room temperature. In this work, the room temperature sensing performance of a Ti
    Sprache Englisch
    Erscheinungsdatum 2022-08-09
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 2379-3694
    ISSN (online) 2379-3694
    DOI 10.1021/acssensors.2c01213
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Directing ligament-mimetic bi-directional cell organization in scaffolds through zone-specific microarchitecture for ligament tissue engineering.

    Sriram, M / Priya, Smriti / Mahajan, Aman / Katti, Dhirendra S

    Biofabrication

    2024  Band 16, Heft 2

    Abstract: Ligament tissues exhibit zone-specific anisotropic cell organization. The cells in ligament-proper are longitudinally oriented, whereas, the cells in epiligament are circumferentially oriented. Therefore, scaffolds developed to regenerate ligament ... ...

    Abstract Ligament tissues exhibit zone-specific anisotropic cell organization. The cells in ligament-proper are longitudinally oriented, whereas, the cells in epiligament are circumferentially oriented. Therefore, scaffolds developed to regenerate ligament tissues should possess adequate architectural features to govern ligament-mimetic bi-directional cell organization. The scaffold architectural features along with ligament-mimetic cell organization may ultimately yield neo-tissues with ligament-like extracellular matrix (ECM) structure and biomechanical properties. Towards this goal, we fabricated a silk/gelatin-based core-shell scaffold (csSG) with zone-specific anisotropic architectural features, wherein, the core of the scaffold possessed longitudinally aligned pores while the shell of the scaffold possessed parallel microgrooves that are aligned circumferentially around the surface of the scaffold. The ligament-mimetic architectural features significantly improved the mechanical properties of the scaffold. Moreover, architectural features of the csSG scaffold governed zone-specific anisotropic organization of cells. The cells in the core were longitudinally oriented as observed in the ligament-proper and the cells on the shell were circumferentially oriented as observed in epiligament. This bi-directional cell orientation partially mimicked the complex cellular network in native ligament tissue. Additionally, both the core and the shell individually supported fibrogenic differentiation of stem cells which further improved their potential for ligament tissue engineering. Further, the aligned pores of the core could govern unidirectional organization of ECM deposited by cells which is crucial for regenerating anisotropic tissues like ligaments. Finally, when implanted subcutaneously in mice, the scaffolds retained their anisotropic architecture for at least 2 weeks, were biocompatible, supported cell infiltration and governed anisotropic organization of cells and ECM. Taken together, the fabricated biomimetic csSG scaffold, through its zone-specific architectural features, could govern ligament-mimetic cellular and ECM organization which is ultimately expected to achieve regeneration of ligament tissues with native-like hierarchical structure and biomechanical properties. Consequently, this study introduces bi-directional structural parameters as design criteria for developing scaffolds for ligament tissue engineering.
    Mesh-Begriff(e) Animals ; Mice ; Tissue Engineering ; Tissue Scaffolds/chemistry ; Biomimetics ; Silk/chemistry ; Ligaments
    Chemische Substanzen Silk
    Sprache Englisch
    Erscheinungsdatum 2024-02-14
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2500944-8
    ISSN 1758-5090 ; 1758-5082
    ISSN (online) 1758-5090
    ISSN 1758-5082
    DOI 10.1088/1758-5090/ad22f2
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Cognitive assessment during awake brain tumor surgery.

    Mahajan, Aman / Mahajan, Charu / Prabhakar, Hemanshu

    Acta neurochirurgica

    2023  Band 165, Heft 9, Seite(n) 2503

    Mesh-Begriff(e) Humans ; Wakefulness ; Brain Neoplasms/surgery ; Neurosurgical Procedures ; Cognition ; Brain Mapping ; Craniotomy
    Sprache Englisch
    Erscheinungsdatum 2023-07-06
    Erscheinungsland Austria
    Dokumenttyp Letter
    ZDB-ID 80010-7
    ISSN 0942-0940 ; 0001-6268
    ISSN (online) 0942-0940
    ISSN 0001-6268
    DOI 10.1007/s00701-023-05688-2
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    Volltext online

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  7. Artikel ; Online: Coronavirus (COVID - 19): Chemical Entities of Biological Interest.

    Mahajan, Aman / Gupta, Princy

    Mini reviews in medicinal chemistry

    2021  Band 21, Heft 17, Seite(n) 2497–2506

    Abstract: Virus, a sub-microscopic infectious agent that replicates only inside the living cells of a host, causes viral infection. Currently, the immediate imperative is to control the combat against novel coronavirus outbreak caused by the COVID-19 virus, which ... ...

    Abstract Virus, a sub-microscopic infectious agent that replicates only inside the living cells of a host, causes viral infection. Currently, the immediate imperative is to control the combat against novel coronavirus outbreak caused by the COVID-19 virus, which started in China and spread all over the world. The domain of travelling has emphasized COVID-19 virus prevention as a serious issue for the safety of human beings. The exponential rise in the number of corona patients is a matter of concern for governing bodies of various countries in spite of countless cooperative efforts put in by citizens, organizations and government. India is now among the top worst hit nation in terms of the spread of COVID-19 pandemic. The present article reviews various state-of-art medicinal approaches available that are presently used to control the spread of coronavirus pandemic.
    Mesh-Begriff(e) Animals ; COVID-19/drug therapy ; COVID-19/epidemiology ; COVID-19/virology ; Humans ; India/epidemiology ; SARS-CoV-2/drug effects
    Sprache Englisch
    Erscheinungsdatum 2021-02-05
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2104081-3
    ISSN 1875-5607 ; 1389-5575
    ISSN (online) 1875-5607
    ISSN 1389-5575
    DOI 10.2174/1389557521666210125145700
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel: Cardiopulmonary nerve stimulation as a novel therapy for cardiac autonomic nervous system modulation.

    Salavatian, Siamak / Spinelli, Julio C / Schaefer, Jeremy A / Libbus, Imad / Mahajan, Aman / Armour, J Andrew

    Frontiers in neuroscience

    2024  Band 18, Seite(n) 1377171

    Sprache Englisch
    Erscheinungsdatum 2024-02-28
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2411902-7
    ISSN 1662-453X ; 1662-4548
    ISSN (online) 1662-453X
    ISSN 1662-4548
    DOI 10.3389/fnins.2024.1377171
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  9. Artikel ; Online: Functionally graded hydrogels with opposing biochemical cues for osteochondral tissue engineering.

    Mahajan, Aman / Zaidi, Zahra Sifat / Shukla, Amit / Saxena, Rakshita / Katti, Dhirendra S

    Biofabrication

    2024  

    Abstract: Osteochondral tissue (OC) repair remains a significant challenge in the field of musculoskeletal tissue engineering. OC tissue displays a gradient structure characterised by variations in both cell types and extracellular matrix components from cartilage ...

    Abstract Osteochondral tissue (OC) repair remains a significant challenge in the field of musculoskeletal tissue engineering. OC tissue displays a gradient structure characterised by variations in both cell types and extracellular matrix components from cartilage to the subchondral bone. These functional gradients in the native tissue have been replicated to engineer osteochondral tissue in vitro. While diverse fabrication methods have been employed to create these microenvironments, emulating the natural gradients and effective regeneration of the tissue continues to present a significant challenge. In this study, we present the design and development of an interpenetrating (IPN) hydrogel with opposing dual biochemical gradients with the aim of regenerating the complete osteochondral unit. The gradients of biochemical cues were generated using an in-house built extrusion system in CMC-Silk IPN hydrogel having improved mechanical strength. Firstly, we fabricated a hydrogel that exhibits a smooth transition of sCMC and TGF-β1 (SCT gradient hydrogel) from the upper to the lower region of the IPN hydrogel, with the intent of regenerating the cartilage layer. Secondly, a hydrogel with a HAp gradient (HAp gradient hydrogel) from the lower to the upper region was fabricated to facilitate the regeneration of the subchondral bone layer. Subsequently, we developed a dual biochemical gradient hydrogel with the goal of regenerating the entire osteochondral unit. The fabricated hydrogel demonstrated a smooth transition of sCMC + TGF-β1 and HAp gradients in opposing directions, along with a blend of both the biochemical cues at the interface. The results showed that the hydrogels having biochemical cues corresponding to the three zones (i.e., cartilage, interface and bone) of dual biochemical gradient hydrogel led to differentiation of BMSCs towards their respective lineages, thereby demonstrating their efficacy in directing the fate of progenitor cells. The developed dual gradient hydrogel provided biochemical signals that have the potential to facilitate tissue growth and regeneration of the entire osteochondral tissue with a smooth transition from cartilage (soft) to bone (hard) tissues. In summary, our study provides a simple and innovative method for incorporating biochemical cues into hydrogels. This promising approach is translatable and has the potential to be extrapolated to other interface tissues. .
    Sprache Englisch
    Erscheinungsdatum 2024-05-02
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2500944-8
    ISSN 1758-5090 ; 1758-5082
    ISSN (online) 1758-5090
    ISSN 1758-5082
    DOI 10.1088/1758-5090/ad467e
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  10. Artikel: Extra-Corporeal Membrane Oxygenation in Pregnancy.

    Romenskaya, Tatsiana / Longhitano, Yaroslava / Mahajan, Aman / Savioli, Gabriele / Voza, Antonio / Tesauro, Manfredi / Zanza, Christian

    Journal of clinical medicine

    2024  Band 13, Heft 6

    Abstract: Extracorporeal membrane oxygenation (ECMO) is a cardiac or pulmonary function support system that is used in cases of refractory organ failure in addition to conventional treatment. Currently, Level I evidence is not yet available, which reflects ... ...

    Abstract Extracorporeal membrane oxygenation (ECMO) is a cardiac or pulmonary function support system that is used in cases of refractory organ failure in addition to conventional treatment. Currently, Level I evidence is not yet available, which reflects improved outcomes with ECMO in pregnant women, the use in pregnancy should be indicated in selected cases and only in specialized centers. We searched articles in the most important scientific databases from 2009 until 31 December 2023 consulting also the site ClinicalTrials.com to find out about studies that have been recently conducted or are currently ongoing. We matched the combination of the following keywords: "ECMO and pregnancy", "H1N1 and pregnancy", "COVID-19 and pregnancy", "ARDS and pregnancy", "ECMO and pregnancy AND (cardiac arrest)". We selected the following number of articles for each keyword combination: "ECMO and pregnancy" (665 articles); "ECMO and influenza H1N1" (384 articles); "pregnancy and influenza H1N1" (1006 articles); "pregnancy and ARDS" (2930 articles); "ECMO and pregnancy and ARDS and influenza H1N1" (24 articles); and "[ECMO and pregnancy AND (cardiac arrest)]" (74 articles). After careful inspection, only 43 papers fitted our scope. There are two types of ECMO: venous-venous (VV-ECMO) and venous-arterial (VA-ECMO). The first-one is necessary to cope with severe hypoxia: oxygen-depleted blood is taken from the venous circulation, oxygenated, and carbon dioxide removed from the extracorporeal circuit and returned to the same venous system. The VA-ECMO is a type of mechanical assistance to the circulatory system that allows to put the failing organ at rest by ensuring adequate oxygenation and systemic de-oxygenation, avoiding multi-organ failure. The main indications for ECMO support in pregnant women are cardiogenic shock, acute respiratory distress syndrome (ARDS), pulmonary embolism, and eclampsia. There are also fetal indications for ECMO, and they are fetal distress, hypoxic-ischemic encephalopathy (HIE), and twin-to-twin transfusion syndrome (TTTS). Until now, based on the outcomes of the numerous clinical studies conducted, ECMO has been shown to be a successful therapeutic strategy in cases where medical treatment has been unsuccessful. In well-selected pregnant patients, it appears to be safe and associated with a low risk of maternal and fetal complications. The aim of this review is to report the main properties of ECMO (VV and VA) and the indications for its use in pregnant women.
    Sprache Englisch
    Erscheinungsdatum 2024-03-13
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13061634
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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