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  1. Article: Hypopharyngeal carcinoma: King Faisal Specialist Hospital and Research Centre experience.

    Mahasin, Z / Khan, B

    Annals of Saudi medicine

    2007  Volume 16, Issue 5, Page(s) 539–544

    Abstract: From 1975 to 1985, 202 patients with hypopharyngeal cancer were seen at King Faisal Specialist Hospital and Research Centre (KFSH&RC). The endoscopic investigation showed that 28.3% of these patients had postcricoid carcinoma; 19.85% had pyriform fossa ... ...

    Abstract From 1975 to 1985, 202 patients with hypopharyngeal cancer were seen at King Faisal Specialist Hospital and Research Centre (KFSH&RC). The endoscopic investigation showed that 28.3% of these patients had postcricoid carcinoma; 19.85% had pyriform fossa carcinoma and 52.9% had involvement of both sites. The pathological diagnosis of all cases was squamous cell carcinoma type. The majority of the patients (62.98%) had T4 lesions, which showed a late presentation to KFSH&RC. Information related to survival was available for a smaller number of patients due to many "lost-to-follow-up" cases. The overall median survival time was 8.5 months (1-110 months). The survival rate for each site was calculated, as well as the staging of the disease and treatment modality used. It appeared that pyriform fossa (median 21 months) had the best survival rate. In addition, the earlier the lesion was detected and the more aggressive the treatment applied, the better the survival rate. Fifty percent of the patients receiving radiation therapy and surgery had a five-year survival rate. Factors other than smoking and/or drinking should be looked for in our community as predisposing to this disease in our population.
    Language English
    Publishing date 2007-03-22
    Publishing country Saudi Arabia
    Document type Journal Article
    ZDB-ID 639014-6
    ISSN 0975-4466 ; 0256-4947
    ISSN (online) 0975-4466
    ISSN 0256-4947
    DOI 10.5144/0256-4947.1996.539
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Chronic Invasive Fungal Rhinosinusitis in Immunocompetent Patients: A Retrospective Chart Review.

    Alotaibi, Naif H / Omar, Omar Abu / Altahan, Mays / Alsheikh, Haifa / Al Mana, Fawziah / Mahasin, Zeyad / Othman, Eyas

    Frontiers in surgery

    2020  Volume 7, Page(s) 608342

    Abstract: Objective: ...

    Abstract Objective:
    Language English
    Publishing date 2020-12-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2773823-1
    ISSN 2296-875X
    ISSN 2296-875X
    DOI 10.3389/fsurg.2020.608342
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  3. Article: Primary oral malignant melanoma metastasis to the brain and breast: A case report and literature review.

    Alqahtani, Saad / Alhefdhi, Amal Y / Almalik, Osama / Anwar, Ihab / Mahmood, Rana / Mahasin, Zeyad / Al-Tweigeri, Taher

    Oncology letters

    2017  Volume 14, Issue 2, Page(s) 1275–1280

    Abstract: Primary oral malignant melanoma is a rare tumor, which is estimated to comprise 0.2-8.0% of all melanoma cases. This type of cancer is fairly uncommon, its prognosis is dismal, and it frequently exhibits a biologically aggressive behavior. The common ... ...

    Abstract Primary oral malignant melanoma is a rare tumor, which is estimated to comprise 0.2-8.0% of all melanoma cases. This type of cancer is fairly uncommon, its prognosis is dismal, and it frequently exhibits a biologically aggressive behavior. The common location of primary oral malignant melanoma is the hard palate and maxillary alveolus. In ~85% of cases, the melanoma will metastasize to the liver, lung, bone and brain early in the course of the disease. The present study reports the case of a 50-year-old premenopausal woman who presented with primary oral malignant spindle cell melanoma (T3bN2aM0) and underwent complete surgical resection followed by an adjuvant course of radiation therapy. After 1 year, the patient presented with sudden onset slurred speech, and upon examination, was found to have left-sided hemiparesis and a hard left breast mass. Workup confirmed breast and brain metastasis. The patient developed lung metastasis 4 weeks later and was referred for palliative care.
    Language English
    Publishing date 2017-06-02
    Publishing country Greece
    Document type Journal Article
    ZDB-ID 2573196-8
    ISSN 1792-1082 ; 1792-1074
    ISSN (online) 1792-1082
    ISSN 1792-1074
    DOI 10.3892/ol.2017.6304
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  4. Article: Multiple bilateral orbital abscesses secondary to nasal furunculosis.

    Mahasin, Z / Saleem, M / Quick, C A

    International journal of pediatric otorhinolaryngology

    2001  Volume 58, Issue 2, Page(s) 167–171

    Abstract: Orbital inflammation secondary to sinus inflammation is a well known entity and has been widely reported. However, nasal furunculosis resulting in orbital inflammation is a rare occurrence. We present a case of a 2-year-old boy who developed multiple ... ...

    Abstract Orbital inflammation secondary to sinus inflammation is a well known entity and has been widely reported. However, nasal furunculosis resulting in orbital inflammation is a rare occurrence. We present a case of a 2-year-old boy who developed multiple bilateral orbital abscesses secondary to nasal furunculosis. To our knowledge such a case has not been reported before.
    MeSH term(s) Abscess/diagnosis ; Abscess/etiology ; Abscess/therapy ; Child, Preschool ; Furunculosis/complications ; Furunculosis/diagnosis ; Furunculosis/therapy ; Humans ; Male ; Nose Diseases/complications ; Nose Diseases/diagnosis ; Nose Diseases/therapy ; Orbital Diseases/diagnosis ; Orbital Diseases/etiology ; Orbital Diseases/therapy ; Staphylococcal Infections/diagnosis ; Staphylococcal Infections/therapy
    Language English
    Publishing date 2001-04-27
    Publishing country Ireland
    Document type Case Reports ; Journal Article
    ZDB-ID 754501-0
    ISSN 1872-8464 ; 0165-5876
    ISSN (online) 1872-8464
    ISSN 0165-5876
    DOI 10.1016/s0165-5876(01)00412-8
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    Zs.A 1507: Show issues Location:
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    Zs.MO 134: Show issues

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  5. Article: Chronic invasive aspergillosis of the paranasal sinuses in immunocompetent hosts from Saudi Arabia.

    Alrajhi, A A / Enani, M / Mahasin, Z / Al-Omran, K

    The American journal of tropical medicine and hygiene

    2001  Volume 65, Issue 1, Page(s) 83–86

    Abstract: In immunocompetent patients, paranasal invasive aspergillosis is rare and has a high recurrence rate. Twenty-three cases of paranasal invasive aspergillosis, involving 14 male and nine female immunocompetent patients were reviewed. All patients were ... ...

    Abstract In immunocompetent patients, paranasal invasive aspergillosis is rare and has a high recurrence rate. Twenty-three cases of paranasal invasive aspergillosis, involving 14 male and nine female immunocompetent patients were reviewed. All patients were cancer-free, HIV-negative, with normal WBC, and none of the patients had received immunosuppressive therapy or corticosteroids. Mean duration of symptoms before diagnosis was 18 months. Aspergillus flavus was the species most frequently isolated. Surgical debridement was performed in all patients followed by antifungal therapy in 18 patients. Mean follow-up duration was 30 months. Fourteen patients relapsed after a mean of 13 months and required an average of 4.3 admissions for repeat surgical evacuation. In a logistic regression model, relapse was not associated with age, duration of symptoms, clinical findings, extent of disease, or mode of therapy. However, patients who were relapse-free tended to have had complete surgical evacuation followed by antifungal therapy.
    MeSH term(s) Adolescent ; Adult ; Antifungal Agents/therapeutic use ; Aspergillosis/drug therapy ; Aspergillosis/surgery ; Aspergillus flavus/growth & development ; Child ; Debridement ; Female ; Humans ; Logistic Models ; Male ; Middle Aged ; Paranasal Sinus Diseases/drug therapy ; Paranasal Sinus Diseases/microbiology ; Paranasal Sinus Diseases/surgery ; Recurrence ; Retrospective Studies ; Risk Factors ; Saudi Arabia
    Chemical Substances Antifungal Agents
    Language English
    Publishing date 2001-08-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2942-7
    ISSN 1476-1645 ; 0002-9637
    ISSN (online) 1476-1645
    ISSN 0002-9637
    DOI 10.4269/ajtmh.2001.65.83
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  6. Article: Superiorly based osteoplastic flap for frontal sinus disease.

    Kudryk, W H / Mahasin, Z

    The Journal of otolaryngology

    1988  Volume 17, Issue 7, Page(s) 395–397

    Abstract: The osteoplastic flap is a widely used technique as an approach to frontal sinus disease. All current textbooks describe the technique with basing the flap inferiorly along the orbital rim and across the naso-frontal suture line. Since 1977, we have had ... ...

    Abstract The osteoplastic flap is a widely used technique as an approach to frontal sinus disease. All current textbooks describe the technique with basing the flap inferiorly along the orbital rim and across the naso-frontal suture line. Since 1977, we have had occasion to base the flap superiorly in eight cases with good results. We feel that the superiorly based flap is ideally indicated in unilateral disease, particularly in the balding male, where a coronal incision would be very obvious. It is also a more direct approach. The skin incision itself can be parallel to the brow or almost identical to a blepharoplasty incision. After the floor of the frontal sinus has been removed (as in a Lynch or Howarth approach), cuts in the anterior wall of the frontal sinus are made under direct vision, and the bone is fractured at the superior extent of the sinus. This is certainly quicker and simpler than the standard approach, where a template is required. The risks of CSF leak are greatly diminished. The surgeon has the option of obliterating the sinus, removing the intersinus septum, or creating a mucoperiosteal flap. Details of the technique and two illustrative cases are presented.
    MeSH term(s) Adult ; Frontal Sinus/surgery ; Humans ; Male ; Paranasal Sinus Diseases/surgery ; Surgical Flaps/methods
    Language English
    Publishing date 1988-12
    Publishing country Canada
    Document type Case Reports ; Journal Article
    ZDB-ID 197688-6
    ISSN 0381-6605
    ISSN 0381-6605
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1130: Show issues Location:
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  7. Article: A pilot study of the relationship between Down's syndrome and hearing loss.

    Kattan, H A / Jarrar, R F / Mahasin, Z Z

    Saudi medical journal

    2000  Volume 21, Issue 10, Page(s) 931–933

    Abstract: Objective: Hearing loss is one of the most common disabilities in children with Down's syndrome. The objective of this study is to investigate the incidence and types of hearing loss in Down's syndrome patients.: Methods: Twenty-six subjects with ... ...

    Abstract Objective: Hearing loss is one of the most common disabilities in children with Down's syndrome. The objective of this study is to investigate the incidence and types of hearing loss in Down's syndrome patients.
    Methods: Twenty-six subjects with Down's syndrome aged between 2 and 17 year old were evaluated during the year 1998, referred randomly by the Pediatric Department and the Down's Syndrome Centre. Screening audiological procedures were used to evaluate these patients, which include behavioral audiometry, play and pure tone audiometry, tympanometry and ABR, which is the measurement of the activity of the auditory pathway structures from the distal auditory nerve to the midbrain using clicks or tonepips.
    Results: The study showed that 35% were found to have normal hearing compared to 4% found to have sensorineural hearing loss, while the majority of patients were found to have a conductive hearing loss (50%).
    Conclusion: Hearing evaluation of children with Down's syndrome revealed a high prevalence of conductive hearing loss. This study proposed that this might be attributed to eustachian tube dysfunction and middle ear ciliary malfunction. Further diagnostic studies need to be carried out.
    MeSH term(s) Acoustic Impedance Tests ; Adolescent ; Audiometry ; Child ; Child, Preschool ; Down Syndrome/complications ; Evoked Potentials, Auditory, Brain Stem ; Hearing Loss, Conductive/diagnosis ; Hearing Loss, Conductive/epidemiology ; Hearing Loss, Conductive/etiology ; Hearing Loss, Sensorineural/diagnosis ; Hearing Loss, Sensorineural/epidemiology ; Hearing Loss, Sensorineural/etiology ; Humans ; Incidence ; Mass Screening/methods ; Pilot Projects ; Prevalence ; Referral and Consultation ; Saudi Arabia/epidemiology
    Language English
    Publishing date 2000-10
    Publishing country Saudi Arabia
    Document type Journal Article
    ZDB-ID 392302-2
    ISSN 1658-3175 ; 0379-5284
    ISSN (online) 1658-3175
    ISSN 0379-5284
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    Zs.B 2330: Show issues Location:
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  8. Article: Leiomyoma of the esophagus and bronchus in a child.

    Al-Bassam, A / Al-Rabeeah, A / Fouda-Neel, K / Mahasin, Z

    Pediatric surgery international

    1998  Volume 13, Issue 1, Page(s) 45–47

    Abstract: Leiomyomas of the esophagus and/or the bronchus have rarely been reported in children. To our knowledge, the simultaneous presence of this tumor in both the esophagus and a bronchus in a child has not been previously reported. A 7-year old boy presented ... ...

    Abstract Leiomyomas of the esophagus and/or the bronchus have rarely been reported in children. To our knowledge, the simultaneous presence of this tumor in both the esophagus and a bronchus in a child has not been previously reported. A 7-year old boy presented with respiratory and esophageal symptoms and was found to have a leiomyoma of the esophagus and right main bronchus. The esophageal leiomyoma was treated with limited myotomy, but bronchoscopic resection was possible for the bronchial lesion. The postoperative result was excellent, with normal swallowing and no residual respiratory problems at 1-year follow-up.
    MeSH term(s) Bronchial Neoplasms/diagnosis ; Bronchial Neoplasms/surgery ; Child ; Esophageal Neoplasms/diagnosis ; Esophageal Neoplasms/surgery ; Humans ; Leiomyoma/surgery ; Magnetic Resonance Imaging ; Male ; Neoplasms, Multiple Primary/diagnosis ; Neoplasms, Multiple Primary/surgery
    Language English
    Publishing date 1998-01
    Publishing country Germany
    Document type Case Reports ; Journal Article
    ZDB-ID 632773-4
    ISSN 0179-0358
    ISSN 0179-0358
    DOI 10.1007/s003830050241
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  9. Article: Transverse sinus thrombosis and venous infarction of the brain following unilateral radical neck dissection.

    Mahasin, Z Z / Saleem, M / Gangopadhyay, K

    The Journal of laryngology and otology

    1998  Volume 112, Issue 1, Page(s) 88–91

    Abstract: Radical neck dissection is one of the commonest procedures performed in any unit dealing with head and neck surgery. Intracranial complications following this procedure are uncommon. Transverse sinus thrombosis and venous infarction of the brain ... ...

    Abstract Radical neck dissection is one of the commonest procedures performed in any unit dealing with head and neck surgery. Intracranial complications following this procedure are uncommon. Transverse sinus thrombosis and venous infarction of the brain following unilateral radical neck dissection have not been reported in the literature. We present a case in which this complication occurred following an uneventful radical neck dissection.
    MeSH term(s) Aged ; Cerebral Infarction/diagnostic imaging ; Cerebral Infarction/etiology ; Female ; Follow-Up Studies ; Humans ; Magnetic Resonance Imaging ; Neck Dissection/adverse effects ; Sinus Thrombosis, Intracranial/diagnostic imaging ; Sinus Thrombosis, Intracranial/etiology ; Tomography, X-Ray Computed
    Language English
    Publishing date 1998-01
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 218299-3
    ISSN 1748-5460 ; 0022-2151
    ISSN (online) 1748-5460
    ISSN 0022-2151
    DOI 10.1017/s0022215100139994
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  10. Article: Pathologic quiz case 2. Castleman disease (giant lymph node hyperplasia).

    Gangopadhyay, K / Mahasin, Z Z / Kfoury, H

    Archives of otolaryngology--head & neck surgery

    1997  Volume 123, Issue 10, Page(s) 1137, 1139

    MeSH term(s) Adult ; Castleman Disease/diagnosis ; Castleman Disease/pathology ; Diagnosis, Differential ; Female ; Head ; Humans ; Neck
    Language English
    Publishing date 1997-10
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 632721-7
    ISSN 1538-361X ; 0886-4470 ; 2168-6181
    ISSN (online) 1538-361X
    ISSN 0886-4470 ; 2168-6181
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