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  1. Article: Chronic Invasive Fungal Rhinosinusitis in Immunocompetent Patients: A Retrospective Chart Review.

    Alotaibi, Naif H / Omar, Omar Abu / Altahan, Mays / Alsheikh, Haifa / Al Mana, Fawziah / Mahasin, Zeyad / Othman, Eyas

    Frontiers in surgery

    2020  Volume 7, Page(s) 608342

    Abstract: Objective: ...

    Abstract Objective:
    Language English
    Publishing date 2020-12-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2773823-1
    ISSN 2296-875X
    ISSN 2296-875X
    DOI 10.3389/fsurg.2020.608342
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Primary oral malignant melanoma metastasis to the brain and breast: A case report and literature review.

    Alqahtani, Saad / Alhefdhi, Amal Y / Almalik, Osama / Anwar, Ihab / Mahmood, Rana / Mahasin, Zeyad / Al-Tweigeri, Taher

    Oncology letters

    2017  Volume 14, Issue 2, Page(s) 1275–1280

    Abstract: Primary oral malignant melanoma is a rare tumor, which is estimated to comprise 0.2-8.0% of all melanoma cases. This type of cancer is fairly uncommon, its prognosis is dismal, and it frequently exhibits a biologically aggressive behavior. The common ... ...

    Abstract Primary oral malignant melanoma is a rare tumor, which is estimated to comprise 0.2-8.0% of all melanoma cases. This type of cancer is fairly uncommon, its prognosis is dismal, and it frequently exhibits a biologically aggressive behavior. The common location of primary oral malignant melanoma is the hard palate and maxillary alveolus. In ~85% of cases, the melanoma will metastasize to the liver, lung, bone and brain early in the course of the disease. The present study reports the case of a 50-year-old premenopausal woman who presented with primary oral malignant spindle cell melanoma (T3bN2aM0) and underwent complete surgical resection followed by an adjuvant course of radiation therapy. After 1 year, the patient presented with sudden onset slurred speech, and upon examination, was found to have left-sided hemiparesis and a hard left breast mass. Workup confirmed breast and brain metastasis. The patient developed lung metastasis 4 weeks later and was referred for palliative care.
    Language English
    Publishing date 2017-06-02
    Publishing country Greece
    Document type Journal Article
    ZDB-ID 2573196-8
    ISSN 1792-1082 ; 1792-1074
    ISSN (online) 1792-1082
    ISSN 1792-1074
    DOI 10.3892/ol.2017.6304
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Obstructive endotracheal lesions of thyroid cancer.

    Ahmed, Mohammed / Saleem, Muhammad / Al-Arifi, Abdullah / Almahfouz, Abdulraof / Mahasin, Zeyad / Al-Sobhi, Saif / Ingemansson, Stig / Taibah, Khalid

    The Journal of laryngology and otology

    2002  Volume 116, Issue 8, Page(s) 613–621

    Abstract: Airway invasion is a life-threatening complication of thyroid cancer. An important issue that deserves better attention is the differentiation between the clinical features of tracheal wall invasion versus those of an obstructive endotracheal lesion. We ... ...

    Abstract Airway invasion is a life-threatening complication of thyroid cancer. An important issue that deserves better attention is the differentiation between the clinical features of tracheal wall invasion versus those of an obstructive endotracheal lesion. We present information on the clinical course, diagnostic modalities utilized, management instituted, along with the prognosis, and follow-up data on a group of patients presenting with obstructive endotracheal lesions of thyroid cancer. Two thousand four hundred and eighty-nine thyroid cancer patients were seen at our institution from December 1975 to May 2000. Thirteen patients presented with symptoms of respiratory distress related to obstructive endotracheal lesions. At presentation, 11 patients underwent endoscopic examination. Imaging studies consisting of I123 whole body scan (WBS), computed tomography/magnetic resonance imaging (CT/MRI) of neck and chest, whole body positron emission tomography using 18-fluoro-2-deoxy-D-glucose ((FDG)PET) were done, as also was determination of the tumour markers, serum thyroglobulin (TG) and calcitonin. Patients were followed for one to 108 months after the initial presentation. Intraluminal tracheal obstruction was severe in eight patients; five had near-total-occlusion. Paralysis of the vocal folds was present in five. Evidence of metastatic disease was present in most patients. Dissociation between iodine uptake and TG synthesis was evident in five patients during follow-up. Four patients died of cancer. Of the nine living patients; cancer persisted in six, recurred in two patients, and remitted in one. This study has identified obstructive endotracheal lesion of thyroid cancer as a distinct entity apart from tracheal wall disease. These data provide evidence that intraluminal tracheal invasion of thyroid cancer is an ominous sign and a frequent cause of morbidity.
    MeSH term(s) Aged ; Aged, 80 and over ; Airway Obstruction/pathology ; Airway Obstruction/radiotherapy ; Airway Obstruction/surgery ; Female ; Follow-Up Studies ; Humans ; Iodine Radioisotopes/therapeutic use ; Male ; Middle Aged ; Morbidity ; Neoplasm Invasiveness ; Thyroid Neoplasms/pathology ; Thyroid Neoplasms/radiotherapy ; Thyroid Neoplasms/surgery ; Thyroidectomy ; Tomography, X-Ray Computed ; Tracheal Stenosis/pathology ; Tracheal Stenosis/surgery ; Tracheostomy
    Chemical Substances Iodine Radioisotopes
    Language English
    Publishing date 2002-08
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 218299-3
    ISSN 1748-5460 ; 0022-2151
    ISSN (online) 1748-5460
    ISSN 0022-2151
    DOI 10.1258/00222150260171614
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ul II Zs.64: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: Stage IV oral cavity carcinoma. Is conventional radical treatment an option?

    Al-Rajhi, Nasser / Saleem, Mohammad / Al-Amro, Abdullah S / El-Enbaby, Ashraf M / El-Husseiny, Gamal A / Mahasin, Zeyad Z / Taibah, Kalid M / Al-Zahrani, Ali M

    Saudi medical journal

    2002  Volume 23, Issue 9, Page(s) 1095–1098

    Abstract: Objective: To evaluate the outcome of radical treatment for patients with stage IV squamous cell carcinoma of the oral cavity.: Methods: Using head and neck tumor database, 57 patients with stage IV non-metastatic invasive squamous cell carcinoma of ... ...

    Abstract Objective: To evaluate the outcome of radical treatment for patients with stage IV squamous cell carcinoma of the oral cavity.
    Methods: Using head and neck tumor database, 57 patients with stage IV non-metastatic invasive squamous cell carcinoma of the oral cavity treated with curative intent at King Faisal Specialist Hospital and Research Center, Riyadh, Kingdom of Saudi Arabia, between July 1992 and June 1998, were identified and retrospectively reviewed.
    Results: Our cohort of patients consisted of 33 males and 24 females, with a median age of 65 years. The primary sites were alveolus (26), tongue (22), buccal mucosa (6), floor of mouth (2) and retromolar trigone (one). Definitive radiotherapy was used in 7 patients, surgery in 17 and combined modality in 33. With a median follow-up for surviving patients of 53-months, the actuarial 5-year overall survival and relapse free survival was 20% and 14%. Tumors arising from the alveolus showed a better outcome as compared to the rest of oral cavity sites with an overall survival and relapse free survival of 32% and 26% compared to 8% and 4% (p value=0.0057 and 0.0038).
    Conclusion: Advanced oral cavity tumors are aggressive neoplasms with a poor outcome to conventional treatment modalities. New approaches like neoadjuvant or concurrent chemoradiotherapy with or without surgery need to be considered and evaluated in prospective studies.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Carcinoma, Squamous Cell/mortality ; Carcinoma, Squamous Cell/pathology ; Carcinoma, Squamous Cell/therapy ; Female ; Humans ; Male ; Middle Aged ; Mouth Neoplasms/mortality ; Mouth Neoplasms/pathology ; Mouth Neoplasms/therapy ; Neoplasm Staging ; Retrospective Studies ; Saudi Arabia ; Treatment Outcome
    Language English
    Publishing date 2002-09
    Publishing country Saudi Arabia
    Document type Journal Article
    ZDB-ID 392302-2
    ISSN 1658-3175 ; 0379-5284
    ISSN (online) 1658-3175
    ISSN 0379-5284
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2330: Show issues Location:
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    Zs.MB 6: Show issues

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