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  1. Article ; Online: In Silico

    Hassan, Mohamed M / Hussain, Mohamed A / Ali, Sababil S / Mahdi, Mohammed A

    Cell transplantation

    2023  Volume 32, Page(s) 9636897231184473

    Abstract: ... ...

    Abstract The
    MeSH term(s) Humans ; HLA-DRB1 Chains/genetics ; Mutation ; Arthritis, Rheumatoid ; Biomedical Research ; Lupus Erythematosus, Systemic
    Chemical Substances HLA-DRB1 Chains
    Language English
    Publishing date 2023-06-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1135816-6
    ISSN 1555-3892 ; 0963-6897
    ISSN (online) 1555-3892
    ISSN 0963-6897
    DOI 10.1177/09636897231184473
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3556: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: Advancements in Vaccine Adjuvants: The Journey from Alum to Nano Formulations.

    Moni, Sivakumar S / Abdelwahab, Siddig Ibrahim / Jabeen, Aamena / Elmobark, Mohamed Eltaib / Aqaili, Duaa / Ghoal, Gassem / Oraibi, Bassem / Farasani, Abdulla Mohammed / Jerah, Ahmed Ali / Alnajai, Mahdi Mohammed A / Mohammad Alowayni, Abdul Majeed Hamad

    Vaccines

    2023  Volume 11, Issue 11

    Abstract: Vaccination is a groundbreaking approach in preventing and controlling infectious diseases. However, the effectiveness of vaccines can be greatly enhanced by the inclusion of adjuvants, which are substances that potentiate and modulate the immune ... ...

    Abstract Vaccination is a groundbreaking approach in preventing and controlling infectious diseases. However, the effectiveness of vaccines can be greatly enhanced by the inclusion of adjuvants, which are substances that potentiate and modulate the immune response. This review is based on extensive searches in reputable databases such as Web of Science, PubMed, EMBASE, Scopus, and Google Scholar. The goal of this review is to provide a thorough analysis of the advances in the field of adjuvant research, to trace the evolution, and to understand the effects of the various adjuvants. Historically, alum was the pioneer in the field of adjuvants because it was the first to be approved for use in humans. It served as the foundation for subsequent research and innovation in the field. As science progressed, research shifted to identifying and exploiting the potential of newer adjuvants. One important area of interest is nano formulations. These advanced adjuvants have special properties that can be tailored to enhance the immune response to vaccines. The transition from traditional alum-based adjuvants to nano formulations is indicative of the dynamism and potential of vaccine research. Innovations in adjuvant research, particularly the development of nano formulations, are a promising step toward improving vaccine efficacy and safety. These advances have the potential to redefine the boundaries of vaccination and potentially expand the range of diseases that can be addressed with this approach. There is an optimistic view of the future in which improved vaccine formulations will contribute significantly to improving global health outcomes.
    Language English
    Publishing date 2023-11-09
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines11111704
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Detection of Nonsynonymous Single Variants in Human HLA-DRB1 Exon 2 Associated with Renal Transplant Rejection.

    Hassan, Mohamed M / Hussain, Mohamed A / Ali, Sababil S / Mahdi, Mohammed A / Mohamed, Nouh Saad / AbdElbagi, Hanadi / Mohamed, Osama / Sherif, Asmaa E / Osman, Wadah / Ibrahim, Sabrin R M / Ghazawi, Kholoud F / Miski, Samar F / Mohamed, Gamal A / Ashour, Ahmed

    Medicina (Kaunas, Lithuania)

    2023  Volume 59, Issue 6

    Abstract: ... ...

    Abstract Background
    MeSH term(s) Humans ; HLA-DRB1 Chains/genetics ; Kidney Transplantation/adverse effects ; Case-Control Studies ; HLA Antigens ; Graft Rejection/genetics ; Exons/genetics ; Alleles
    Chemical Substances HLA-DRB1 Chains ; HLA Antigens
    Language English
    Publishing date 2023-06-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina59061116
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6270: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Implementation and evaluation of a Project ECHO telementoring program for the Namibian HIV workforce.

    Bikinesi, Leonard / O'Bryan, Gillian / Roscoe, Clay / Mekonen, Tadesse / Shoopala, Naemi / Mengistu, Assegid T / Sawadogo, Souleymane / Agolory, Simon / Mutandi, Gram / Garises, Valerie / Pati, Rituparna / Tison, Laura / Igboh, Ledor / Johnson, Carla / Rodriguez, Evelyn M / Ellerbrock, Tedd / Menzies, Heather / Baughman, Andrew L / Brandt, Laura /
    Forster, Norbert / Scott, John / Wood, Brian / Unruh, Kenton T / Arora, Sanjeev / Iandiorio, Michelle / Kalishman, Summers / Zalud-Cerrato, Sarah / Lehmer, Jutta / Lee, Stephen / Mahdi, Mohammed A / Spedoske, Samantha / Zuber, Alexandra / Reilley, Brigg / Ramers, Christian B / Hamunime, Ndapewa / O'Malley, Gabrielle / Struminger, Bruce

    Human resources for health

    2020  Volume 18, Issue 1, Page(s) 61

    Abstract: Background: The Namibian Ministry of Health and Social Services (MoHSS) piloted the first HIV Project ECHO (Extension for Community Health Outcomes) in Africa at 10 clinical sites between 2015 and 2016. Goals of Project ECHO implementation included ... ...

    Abstract Background: The Namibian Ministry of Health and Social Services (MoHSS) piloted the first HIV Project ECHO (Extension for Community Health Outcomes) in Africa at 10 clinical sites between 2015 and 2016. Goals of Project ECHO implementation included strengthening clinical capacity, improving professional satisfaction, and reducing isolation while addressing HIV service challenges during decentralization of antiretroviral therapy.
    Methods: MoHSS conducted a mixed-methods evaluation to assess the pilot. Methods included pre/post program assessments of healthcare worker knowledge, self-efficacy, and professional satisfaction; assessment of continuing professional development (CPD) credit acquisition; and focus group discussions and in-depth interviews. Analysis compared the differences between pre/post scores descriptively. Qualitative transcripts were analyzed to extract themes and representative quotes.
    Results: Knowledge of clinical HIV improved 17.8% overall (95% confidence interval 12.2-23.5%) and 22.3% (95% confidence interval 13.2-31.5%) for nurses. Professional satisfaction increased 30 percentage points. Most participants experienced reduced professional isolation (66%) and improved CPD credit access (57%). Qualitative findings reinforced quantitative results. Following the pilot, the Namibia MoHSS Project ECHO expanded to over 40 clinical sites by May 2019 serving more than 140 000 people living with HIV.
    Conclusions: Similar to other Project ECHO evaluation results in the United States of America, Namibia's Project ECHO led to the development of ongoing virtual communities of practice. The evaluation demonstrated the ability of the Namibia HIV Project ECHO to improve healthcare worker knowledge and satisfaction and decrease professional isolation.
    MeSH term(s) Focus Groups ; HIV Infections/drug therapy ; Health Personnel ; Humans ; Program Evaluation ; United States ; Workforce
    Language English
    Publishing date 2020-09-01
    Publishing country England
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S.
    ISSN 1478-4491
    ISSN (online) 1478-4491
    DOI 10.1186/s12960-020-00503-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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