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  1. AU="Mahfouz, Amira Y"
  2. AU="Ayyappan, Sabarish"
  3. AU=Wang Kevin L-C
  4. AU="Lukas T. Hirschwald"
  5. AU="Morley-Davies, A"
  6. AU="Felsberg, Gary J"
  7. AU="Bogen, Oliver"
  8. AU="de Portu, Simona"
  9. AU="Janssens, Rick"

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  1. Artikel ; Online: Efficacy of endophytic bacteria as promising inducers for enhancing the immune responses in tomato plants and managing Rhizoctonia root-rot disease.

    Abbas, Mona M / Ismael, Walaa H / Mahfouz, Amira Y / Daigham, Ghadir E / Attia, Mohamed S

    Scientific reports

    2024  Band 14, Heft 1, Seite(n) 1331

    Abstract: Around the world, a variety of crops, including tomatoes, suffer serious economic losses due to the Rhizoctonia root-rot disease. Herein, Bacillus velezensis, Bacillus megaterium, and Herpaspirillum huttiense isolated from strawberry (Fragaria chiloensis ...

    Abstract Around the world, a variety of crops, including tomatoes, suffer serious economic losses due to the Rhizoctonia root-rot disease. Herein, Bacillus velezensis, Bacillus megaterium, and Herpaspirillum huttiense isolated from strawberry (Fragaria chiloensis var. ananassa) plants were pragmatic as plant growth promotors for battling the Rhizoctonia root rot disease and bringing about defense mechanisms as well as growth promotional strategies in tomato plants. These endophytic bacteria demonstrated potent antifungal activity against R. solani in vitro along in vivo. Data explained that the isolated endophytic bacteria could produce Indole acetic acid, Gibberellic acid GA, and siderophore as well as solubilize phosphate in the soil. The consortium of (Bacillus velezensis, Bacillus megaterium, and Herpaspirillum huttiense) increased the protection % against Rhizoctonia infection by (79.4%), followed by B. velezensis by (73.52%), H. huttiense by (70.5%), and B. megaterium by (67.64%), respectively. There was an increase in soluble proteins and carbohydrates in infected plants treated with a consortium of endophytic bacteria by 30.7% and 100.2% over untreated infected plants, respectively. Applying endophytic bacteria either alone or in combination lowered the level of malondialdehyde MDA and hydrogen peroxide H
    Mesh-Begriff(e) Solanum lycopersicum ; Rhizoctonia ; Hydrogen Peroxide ; Bacteria ; Immunity ; Plant Diseases/prevention & control ; Plant Diseases/microbiology ; Bacillus
    Chemische Substanzen Hydrogen Peroxide (BBX060AN9V)
    Sprache Englisch
    Erscheinungsdatum 2024-01-15
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-51000-8
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Production and characterization of melanin pigment from black fungus Curvularia soli AS21 ON076460 assisted gamma rays for promising medical uses.

    Abd-El-Aziz, Amira S / Abed, Nermine N / Mahfouz, Amira Y / Fathy, Rasha Mohammad

    Microbial cell factories

    2024  Band 23, Heft 1, Seite(n) 68

    Abstract: Owing to the growing need for natural materials in different fields, studying melanin production from biological sources is imperative. In the current study, the extracellular melanin pigment was produced by the fungus Curvularia soli AS21 ON076460. The ... ...

    Abstract Owing to the growing need for natural materials in different fields, studying melanin production from biological sources is imperative. In the current study, the extracellular melanin pigment was produced by the fungus Curvularia soli AS21 ON076460. The factors that affect the production of melanin were optimized by the Plackett-Burman design (P-BD). The effect of gamma irradiation on melanin productivity was investigated. The maximum melanin yield (3.376 mg/L) was elicited by a stimulus of gamma irradiation at 1.0 kGy. The results evoked that, Curvularia soli AS21 ON076460 melanin exhibited excellent antimicrobial activity against all tested bacteria and fungi. Klebsiella pneumoniae ATCC 13883 and P. digitatum were mostly affected by melanin registering the inhibition zone diameters of 37.51 ± 0.012 and 44.25 ± 0.214 mm, respectively. Moreover, Curvularia soli AS21 ON076460 melanin indicated a significant antiviral efficacy (77% inhibition) of Herpes simplex virus (HSV1). The melanin pigment showed antioxidant activities with IC
    Mesh-Begriff(e) Humans ; Melanins ; Gamma Rays ; Fungi/metabolism ; Curvularia/metabolism
    Chemische Substanzen Melanins
    Sprache Englisch
    Erscheinungsdatum 2024-02-26
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2091377-1
    ISSN 1475-2859 ; 1475-2859
    ISSN (online) 1475-2859
    ISSN 1475-2859
    DOI 10.1186/s12934-024-02335-y
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Enhanced Production, Cloning, and Expression of a Xylanase Gene from Endophytic Fungal Strain

    Ellatif, Sawsan Abd / Abdel Razik, Elsayed S / Al-Surhanee, Ameena A / Al-Sarraj, Faisal / Daigham, Ghadir E / Mahfouz, Amira Y

    Journal of fungi (Basel, Switzerland)

    2022  Band 8, Heft 5

    Abstract: ... ...

    Abstract Trichoderma
    Sprache Englisch
    Erscheinungsdatum 2022-04-25
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2784229-0
    ISSN 2309-608X ; 2309-608X
    ISSN (online) 2309-608X
    ISSN 2309-608X
    DOI 10.3390/jof8050447
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel: Assessment of probiotic efficacy and anticancer activities of Lactiplantibacillus plantarum ESSG1 (MZ683194.1) and Lactiplantibacillus pentosus ESSG2 (MZ683195.1) isolated from dairy products

    Abd Ellatif, Sawsan A. / Bouqellah, Nahla Alsayed / Abu-Serie, Marwa M. / Razik, Elsayed S. Abdel / AL-surhanee, Ameena A. / Askary, Ahmad El / Daigham, Ghadir E. / Mahfouz, Amira Y.

    Environmental science and pollution research. 2022 June, v. 29, no. 26

    2022  

    Abstract: Resistance to antibiotics is on the rise, and its indiscriminate usage has resulted in human and animal management constraints. In the research for an innovative treatment to diminish antimicrobial resistance, lactic acid bacteria (LAB) throw light on ... ...

    Abstract Resistance to antibiotics is on the rise, and its indiscriminate usage has resulted in human and animal management constraints. In the research for an innovative treatment to diminish antimicrobial resistance, lactic acid bacteria (LAB) throw light on diminishing this problem in public health. As a result, this paper looked at the efficacy of LAB isolates and their active metabolites to combat pathogens, reduce antibiotic use in clinical settings, and explore the anticancer potential of 8 strains of LAB isolated from dairy products. Antifungal and antibacterial potential of LAB isolates against selected crop pathogenic fungi and food pathogenic bacteria had been estimated. Results revealed that all isolates exert antioxidant efficacy relating to DPPH, NO scavenging ability, reducing power, superoxide anion, hydroxyl radical, and anti-lipid peroxidation potential. Additionally, 12B isolate exert the highest anticancer upshot with IC₅₀ values of 43.98 ± 0.4; 36.7 ± 0.6, 43.1 ± 0.8, and 35.1 ± 0.3 μg/ml, versus Caco-2, MCF-7, HepG-2, and PC3 cell lines respectively, whereas 13B isolate significantly had the highest selectivity index between peripheral blood mononuclear cells (PBMCs) and the tested human cancer cell lines compared to 5-fluorouracil. 13B was the most apoptosis-dependent death inducer for all human cancer cell lines besides exerting the lowest percentage of apoptosis against PBMCs suggesting its safety against PBMCs. The most promising strains 12B and 13B were identified by 16S rRNA sequencing as Lactiplantibacillus plantarum ESSG1 (MZ683194.1) and Lactiplantibacillus pentosus ESSG2 (MZ683195.1). LAB and their extracts are superb substitutive, safe, and efficient antimicrobial, antioxidant, and antitumor curative agents.
    Schlagwörter animal husbandry ; antibacterial properties ; antibiotic resistance ; antibiotics ; antioxidant activity ; apoptosis ; death ; fluorouracil ; humans ; hydroxyl radicals ; lactic acid ; metabolites ; neoplasm cells ; peroxidation ; pollution ; probiotics ; public health ; research ; superoxide anion
    Sprache Englisch
    Erscheinungsverlauf 2022-06
    Umfang p. 39684-39701.
    Erscheinungsort Springer Berlin Heidelberg
    Dokumenttyp Artikel
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-022-18537-z
    Datenquelle NAL Katalog (AGRICOLA)

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  5. Artikel ; Online: Immunomodulatory Efficacy-Mediated Anti-HCV and Anti-HBV Potential of Kefir Grains; Unveiling the In Vitro Antibacterial, Antifungal, and Wound Healing Activities.

    Ellatif, Sawsan Abd / Abdel Razik, Elsayed S / Abu-Serie, Marwa M / Mahfouz, Ahmed / Shater, Abdullah F / Saleh, Fayez M / Hassan, Mohamed M / Alsanie, Walaa F / Altalhi, Abdullah / Daigham, Ghadir E / Mahfouz, Amira Y

    Molecules (Basel, Switzerland)

    2022  Band 27, Heft 6

    Abstract: The utilization of fermented foods with health-promoting properties is becoming more popular around the world. Consequently, kefir, a fermented milk beverage made from kefir grains, was shown in numerous studies to be a probiotic product providing ... ...

    Abstract The utilization of fermented foods with health-promoting properties is becoming more popular around the world. Consequently, kefir, a fermented milk beverage made from kefir grains, was shown in numerous studies to be a probiotic product providing significant health benefits. Herein, we assessed the antibacterial and antifungal potential of kefir against a variety of pathogenic bacteria and fungi. This study also showed the effectiveness of kefir in healing wounds in human gastric epithelial cells (GES-1) by (80.78%) compared with control (55.75%) within 48 h. The quantitative polymerase chain reaction (qPCR) results of kefir-treated HCV- or HBV- infected cells found that 200 µg/mL of kefir can eliminate 92.36% of HCV and 75.71% of HBV relative to the untreated infected cells, whereas 800 µg/mL (the highest concentration) completely eradicated HCV and HBV. Moreover, the estimated IC
    Mesh-Begriff(e) Anti-Bacterial Agents/analysis ; Antifungal Agents/analysis ; Humans ; Kefir/analysis ; Probiotics ; Wound Healing
    Chemische Substanzen Anti-Bacterial Agents ; Antifungal Agents
    Sprache Englisch
    Erscheinungsdatum 2022-03-21
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules27062016
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 81: Hefte anzeigen

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  6. Artikel ; Online: Assessment of probiotic efficacy and anticancer activities of Lactiplantibacillus plantarum ESSG1 (MZ683194.1) and Lactiplantibacillus pentosus ESSG2 (MZ683195.1) isolated from dairy products.

    Abd Ellatif, Sawsan A / Bouqellah, Nahla Alsayed / Abu-Serie, Marwa M / Razik, Elsayed S Abdel / Al-Surhanee, Ameena A / Askary, Ahmad El / Daigham, Ghadir E / Mahfouz, Amira Y

    Environmental science and pollution research international

    2022  Band 29, Heft 26, Seite(n) 39684–39701

    Abstract: Resistance to antibiotics is on the rise, and its indiscriminate usage has resulted in human and animal management constraints. In the research for an innovative treatment to diminish antimicrobial resistance, lactic acid bacteria (LAB) throw light on ... ...

    Abstract Resistance to antibiotics is on the rise, and its indiscriminate usage has resulted in human and animal management constraints. In the research for an innovative treatment to diminish antimicrobial resistance, lactic acid bacteria (LAB) throw light on diminishing this problem in public health. As a result, this paper looked at the efficacy of LAB isolates and their active metabolites to combat pathogens, reduce antibiotic use in clinical settings, and explore the anticancer potential of 8 strains of LAB isolated from dairy products. Antifungal and antibacterial potential of LAB isolates against selected crop pathogenic fungi and food pathogenic bacteria had been estimated. Results revealed that all isolates exert antioxidant efficacy relating to DPPH, NO scavenging ability, reducing power, superoxide anion, hydroxyl radical, and anti-lipid peroxidation potential. Additionally, 12B isolate exert the highest anticancer upshot with IC
    Mesh-Begriff(e) Animals ; Anti-Bacterial Agents/pharmacology ; Anti-Infective Agents ; Antioxidants/pharmacology ; Caco-2 Cells ; Dairy Products ; Humans ; Leukocytes, Mononuclear ; Probiotics/pharmacology ; RNA, Ribosomal, 16S/genetics
    Chemische Substanzen Anti-Bacterial Agents ; Anti-Infective Agents ; Antioxidants ; RNA, Ribosomal, 16S
    Sprache Englisch
    Erscheinungsdatum 2022-02-02
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-022-18537-z
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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