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Book ; Thesis: Sonographische Untersuchung der Milz beim stumpfen Bauchtrauma

Mahlke, Lutz

eine Normwertbestimmung der Größe

2008

Author's details	vorgelegt von Lutz Mahlke
Subject code	617.026
Language	German
Size	III, 63 Bl. : Ill., graph. Darst.
Edition	[Mikrofiche-Ausg.]
Publishing country	Germany
Document type	Book ; Thesis
Thesis / German Habilitation thesis	Göttingen, Univ., Diss., 2008
HBZ-ID	HT016817931
Database	Catalogue ZB MED Medicine, Health

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Article ; Online: Unravelling variations: an examination of entry point selection in proximal femoral cephalomedullary nailing.

Lisitano, Leonard / Wulff, Laura / Schmidt, Jürgen / Sieland, Christoph / Mahlke, Lutz / Röttinger, Timon / Cifuentes, Jairo / Mayr, Edgar / Rau, Kim

Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology

2024 Volume 25, Issue 1, Page(s) 23

Abstract: Background: The exact positioning of the cephalomedullary (CM) nail entry point for managing femoral fractures remains debatable, with significant implications for fracture reduction and postoperative complications. This study aimed to explore the ... ...

Abstract	Background: The exact positioning of the cephalomedullary (CM) nail entry point for managing femoral fractures remains debatable, with significant implications for fracture reduction and postoperative complications. This study aimed to explore the variability in the selection of the entry point among trauma surgeons, hypothesizing potential differences and their association with surgeon experience. Methods: In this prospective multicenter study, 16 participants, ranging from residents to senior specialists, partook in a simulation wherein they determined the optimal entry point for the implantation of a proximal femoral nail antirotation (PFN-A; DePuy Synthes) in various femora. The inter- and intra-observer variability was calculated, along with comprehensive descriptive statistical analysis, to assess the variability in entry point selection and the impact of surgeon experience. Results: In this study, the mean distance from the selected entry points to the calculated mean entry point was 3.98 mm, with a smaller distance observed among surgeons with more than 500 implantations (ANOVA, p = 0.050). Intra-surgeon variability for identical femora averaged at 5.14 mm, showing no significant differences across various levels of surgical experience or training. Notably, 13.6% of selected entry points would not allow a proper intramedullary positioning of the implant, thereby rendering anatomical repositioning unfeasible. Among these impossible entry points, a significant skew towards anterior placement was observed (70.6% of the impossible entry points), with a smaller fraction being overly lateral (27.5%) or medial (13.7%). On a patient level, the impossibility rate varied widely from 0 to 35% among the different femora examined, with a significantly higher rate seen in younger patients (mean age 55.02 versus 60.32; t-test for independent samples, p = 0.04). Conclusions: Significant variations exist in surgeons' selection of entry points for proximal femoral nailing, underscoring the task's complexity. Experience does not prevent the choice of unfeasible entry points, emphasizing the inadequacy of a universal approach and pointing towards the necessity for a patient-specific strategy for improved outcomes. Trial registration number: DRKS00032465.
MeSH term(s)	Female ; Humans ; Male ; Bone Nails ; Clinical Competence ; Femoral Fractures/surgery ; Fracture Fixation, Intramedullary/methods ; Fracture Fixation, Intramedullary/instrumentation ; Observer Variation ; Prospective Studies
Language	English
Publishing date	2024-04-23
Publishing country	Italy
Document type	Clinical Trial ; Journal Article ; Multicenter Study
ZDB-ID	2043336-0
ISSN	1590-9999 ; 1590-9921
ISSN (online)	1590-9999
ISSN	1590-9921
DOI	10.1186/s10195-024-00760-8
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Chirurgie in der SARS-CoV-2-Pandemie : Empfehlungen zum operativen Vorgehen.

Mahlke, Lutz / Flohé, Sascha / Matthes, Gerrit / Paffrath, Thomas / Wagner, Frithjof / Wölfl, Christoph

Der Unfallchirurg

2020 Volume 123, Issue 7, Page(s) 571–578

Abstract: Background: In February 2020 Germany was also hit by the SARS-CoV‑2 pandemic. Even patients infected by SARS-CoV‑2 or COVID-19 may need operative procedures. Currently, no uniform recommendations exist on precautions to be taken when operating on these ... ...

Title translation	Surgery during the SARS-CoV-2 pandemic : Recommendations on operative procedures.
Abstract	Background: In February 2020 Germany was also hit by the SARS-CoV‑2 pandemic. Even patients infected by SARS-CoV‑2 or COVID-19 may need operative procedures. Currently, no uniform recommendations exist on precautions to be taken when operating on these patients. Furthermore, they may differ from one hospital to another. Methods: The task force COVID-19 of the emergency, intensive and severely injured section of the German Trauma Society (DGU e. V.) has developed consensus-based recommendations on surgical treatment of patients with SARS-CoV‑2 infections. Great importance is placed on the implementation in hospitals at all levels of care. Results: The indications for surgical interventions in patients with COVID-19 infections require an extremely critical evaluation. When indicated these surgical intervention should ideally be performed in a separate operating theater. All personnel involved should wear personal protective equipment with FFP2 masks, face shields and double gloves. The emergency team in the resuscitation bay should generally wear the same personal protective equipment. Special training is mandatory and the exposure of team members should be minimized. Conclusion: The recommendations are principally used for all kinds of surgery and comply with the currently available knowledge. Nevertheless, all recommendations represent a compromise between maximum safety of all medical staff and practicability in the routine hospital workflow.
MeSH term(s)	Betacoronavirus ; COVID-19 ; Coronavirus Infections ; General Surgery ; Germany ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
Keywords	covid19
Language	German
Publishing date	2020-06-02
Publishing country	Germany
Document type	Journal Article ; Review
ZDB-ID	605965-x
ISSN	1433-044X ; 0177-5537
ISSN (online)	1433-044X
ISSN	0177-5537
DOI	10.1007/s00113-020-00830-6
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book: Advanced Trauma Life Support (ATLS)

Arnscheidt, Christian / Kronenberg, Antje / Mahlke, Lutz / Vieten, Markus

2015

Title translation	Advanced Trauma Life Support (ATLS ) <dt.>
Institution	American College of Surgeons / Committee on Trauma
Author's details	American College of Surgeons Committee on Trauma (Hrsg.) Übers. aus dem Engl.: Markus Vieten. Redakt. Bearb.: Antje Kronenberg. Dt. Bearb. und fachl. Begutachtung durch Dt. Gesellschaft für Unfallchirurgie (DGU), vertreten durch : Christian Arnscheidt ... Koordination der fachlichen Begutachtung: Lutz Mahlke
Keywords	Notfalltherapie ; Polytrauma ; Ambulanz
Language	German
Size	XXVIII, 316 S., Ill., graph. Darst., 270 mm x 210 mm
Edition	1., dt. Aufl. auf Grundl. der 9. amerikan. Aufl.
Publisher	Elsevier, Urban & Fischer
Publishing place	München
Document type	Book
Note	Literaturangaben
ISBN	343748205X ; 9783437482052
Database	Former special subject collection: coastal and deep sea fishing

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Article: Chirurgie in der SARS-CoV-2-Pandemie : Empfehlungen zum operativen Vorgehen./ [Surgery during the SARS-CoV-2 pandemic : Recommendations on operative procedures]

Mahlke, Lutz / Flohé, Sascha / Matthes, Gerrit / Paffrath, Thomas / Wagner, Frithjof / Wölfl, Christoph

Unfallchirurg

Abstract: BACKGROUND: In February 2020 Germany was also hit by the SARS-CoV2 pandemic. Even patients infected by SARS-CoV2 or COVID-19 may need operative procedures. Currently, no uniform recommendations exist on precautions to be taken when operating on these ... ...

Abstract	BACKGROUND: In February 2020 Germany was also hit by the SARS-CoV2 pandemic. Even patients infected by SARS-CoV2 or COVID-19 may need operative procedures. Currently, no uniform recommendations exist on precautions to be taken when operating on these patients. Furthermore, they may differ from one hospital to another. METHODS: The task force COVID-19 of the emergency, intensive and severely injured section of the German Trauma Society (DGU e.â¯V.) has developed consensus-based recommendations on surgical treatment of patients with SARS-CoV2 infections. Great importance is placed on the implementation in hospitals at all levels of care. RESULTS: The indications for surgical interventions in patients with COVID-19 infections require an extremely critical evaluation. When indicated these surgical intervention should ideally be performed in a separate operating theater. All personnel involved should wear personal protective equipment with FFP2 masks, face shields and double gloves. The emergency team in the resuscitation bay should generally wear the same personal protective equipment. Special training is mandatory and the exposure of team members should be minimized. CONCLUSION: The recommendations are principally used for all kinds of surgery and comply with the currently available knowledge. Nevertheless, all recommendations represent a compromise between maximum safety of all medical staff and practicability in the routine hospital workflow.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #506029
Database	COVID19

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Article ; Online: Chirurgie in der SARS-CoV-2-Pandemie ; Empfehlungen zum operativen Vorgehen

Mahlke, Lutz / Flohé, Sascha / Matthes, Gerrit / Paffrath, Thomas / Wagner, Frithjof / Wölfl, Christoph

Der Unfallchirurg

2020 Volume 123, Issue 7, Page(s) 571–578

Keywords	Surgery ; Emergency Medicine ; Orthopedics and Sports Medicine ; covid19
Language	German
Publisher	Springer Science and Business Media LLC
Publishing country	us
Document type	Article ; Online
ZDB-ID	605965-x
ISSN	1433-044X ; 0177-5537
ISSN (online)	1433-044X
ISSN	0177-5537
DOI	10.1007/s00113-020-00830-6
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: S2e-Leitlinie „Distale Radiusfraktur“.

Chirurgie (Heidelberg, Germany)

2023 Volume 94, Issue 11, Page(s) 965–966

Title translation	Guideline Report Distal radius fracture.
MeSH term(s)	Humans ; Wrist Fractures ; Radius Fractures/diagnostic imaging ; Radius Fractures/therapy ; Fracture Fixation, Internal
Language	German
Publishing date	2023-10-19
Publishing country	Germany
Document type	News
ISSN	2731-698X
ISSN (online)	2731-698X
DOI	10.1007/s00104-023-01949-z
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Präklinisches Polytrauma-Management

Seekamp, Andreas / Mahlke, Lutz

Notfallmedizin up2date

2006 Volume 1, Issue 02, Page(s) 145–161

Language	German
Publishing date	2006-01-01
Publishing place	Stuttgart ; New York
Document type	Article
ZDB-ID	2255461-0
ISSN	1862-6955 ; 1611-6550
ISSN (online)	1862-6955
ISSN	1611-6550
DOI	10.1055/s-2006-924653
Database	Thieme publisher's database

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Article ; Online: Is dopexamine superior to dopamine in the treatment of multiple trauma patients--a prospective, double-blind, randomised study.

Probst, Christian / Hildebrand, Frank / van Griensven, Martijn / Baur, Hellmut / Mahlke, Lutz / Krettek, Christian / Pape, Hans-Christoph / Grotz, Martin Rolf Wolfgang

Injury

2010 Volume 41, Issue 5, Page(s) 499–505

Abstract: Background: The goal of this prospective, randomised, double-blind clinical trial study was to assess the effects of dopexamine hydrochloride on organ failure, inflammatory mediators and splanchnic oxygenation in blunt multiple trauma patients at high ... ...

Abstract	Background: The goal of this prospective, randomised, double-blind clinical trial study was to assess the effects of dopexamine hydrochloride on organ failure, inflammatory mediators and splanchnic oxygenation in blunt multiple trauma patients at high risk of multiple organ dysfunction syndrome (MODS). Methods: We performed a prospective randomised controlled trial on 30 consecutive blunt multiple trauma patients with ISS>or=16, age 18-60 years and initial blood pressure >or=120 mmHg initially admitted to our level I trauma centre. Patients were randomised to treatment with dopamine (n=15) or dopexamine (n=15) for 48 h after admission. Outcome in terms of mortality, MODS, splanchnic perfusion, complications, duration of stay was statistically analysed. Results: Dopexamine treatment was associated with impaired organ function and an increased duration of ventilation and ICU stay compared with patients who received dopamine treatment. The acute inflammatory response was increased in the Dopexamine group while a decreased pHi and MEGX formation and increased serum lactate levels were measured. Conclusions: The indication to use dopexamine hydrochloride appears questionable. In the absence of an antiinflammatory effect, dopexamine demonstrated a disadvantageous ICU course in regards to the organ function and the duration of treatment. In addition, a decreased pHi and MEGX formation suggested a deterioration of splanchnic oxygenation.
MeSH term(s)	Adolescent ; Adult ; Blood Pressure/drug effects ; Critical Care ; Dopamine/analogs & derivatives ; Dopamine/therapeutic use ; Double-Blind Method ; Female ; Gastric Mucosa/metabolism ; Humans ; Length of Stay ; Lidocaine/analogs & derivatives ; Lidocaine/metabolism ; Male ; Middle Aged ; Multiple Organ Failure/drug therapy ; Multiple Organ Failure/metabolism ; Multiple Organ Failure/mortality ; Multiple Trauma/complications ; Multiple Trauma/metabolism ; Multiple Trauma/mortality ; Oxygen Consumption/drug effects ; Prospective Studies ; Respiration, Artificial ; Splanchnic Circulation/drug effects ; Trauma Severity Indices ; Vasodilator Agents/therapeutic use ; Viscera/blood supply ; Wounds, Nonpenetrating/complications ; Wounds, Nonpenetrating/metabolism ; Wounds, Nonpenetrating/mortality ; Young Adult
Chemical Substances	Vasodilator Agents ; dopexamine (398E7Z7JB5) ; Lidocaine (98PI200987) ; monoethylglycinexylidide (D8Q99HC770) ; Dopamine (VTD58H1Z2X)
Language	English
Publishing date	2010-05
Publishing country	Netherlands
Document type	Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
ZDB-ID	218778-4
ISSN	1879-0267 ; 0020-1383
ISSN (online)	1879-0267
ISSN	0020-1383
DOI	10.1016/j.injury.2009.06.018
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Article ; Online: 30 years of polytrauma care: An analysis of the change in strategies and results of 4849 cases treated at a single institution.

Probst, Christian / Pape, Hans-Christoph / Hildebrand, Frank / Regel, Gerd / Mahlke, Lutz / Giannoudis, Peter / Krettek, Christian / Grotz, Martin Rolf Wolfgang

Injury

2009 Volume 40, Issue 1, Page(s) 77–83

Abstract: The quality and progress of treatment of 4849 multiple trauma patients treated at one institution was reviewed retrospectively. Three periods, 1975-1984 (decade I; n=1469) and 1985-1994 (decade II; n=1937) and 1995-2004 (decade III; n=1443) were compared. ...

Abstract	The quality and progress of treatment of 4849 multiple trauma patients treated at one institution was reviewed retrospectively. Three periods, 1975-1984 (decade I; n=1469) and 1985-1994 (decade II; n=1937) and 1995-2004 (decade III; n=1443) were compared. 65% of multiple trauma patients had cerebral injuries, 58% thoracic trauma and 81% extremity fractures (37% open injuries). Injury combinations decreased during all decades with head/extremity injuries being the most common combination. Throughout the three decades pre-hospital care became more aggressive with an increase of intravenous fluid resuscitation (I: 80%, II: 97%, III: 98%). Chest tube insertion decreased after an initial increase (I: 41%, II: 83%, III: 27%) as well as intubation (I: 82%, II: 94%, III: 59%). Rescue times were progressively shortened. For initial clinical diagnosis of massive abdominal haemorrhage ultrasound (I: 17%, II: 92%, III: 97%) replaced peritoneal lavage (I: 44%, II: 28%, III: 0%). CT-scans were used more frequently for the initial diagnosis of head injuries and other injuries to the trunk throughout the observation time. With regard to complications, acute renal failure decreased by half (I: 8.4%; II: 3.7%; III: 3.9%), ARDS initially decreased but increased again in the last decade (I: 18.1%, II: 13.4%, III: 15.3%), whereas the rate of multiple organ dysfunction syndrome (MODS) increased continuously (I: 14.2%, II: 18.9%, III: 19.8%) probably due to a decline of the mortality rate from 37% in the first to 22% in the second and 18% in the third decade and parallel increase of the time of death. These treatment results summarise the enormous clinical effort as well as medical progress in polytrauma management over the past 30 years. Further reduction of mortality is desirable, but probably only possible when immediate causal therapy of later posttraumatic organ failure can be established.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; Child, Preschool ; Clinical Protocols/standards ; Emergencies ; Emergency Medical Services/trends ; Female ; Fluid Therapy/methods ; Humans ; Infant ; Infant, Newborn ; Male ; Middle Aged ; Multiple Organ Failure/mortality ; Multiple Organ Failure/therapy ; Multiple Trauma/mortality ; Multiple Trauma/surgery ; Multiple Trauma/therapy ; Resuscitation ; Retrospective Studies ; Treatment Outcome ; Wounds, Nonpenetrating/mortality ; Wounds, Nonpenetrating/surgery ; Wounds, Nonpenetrating/therapy
Language	English
Publishing date	2009-01
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	218778-4
ISSN	1879-0267 ; 0020-1383
ISSN (online)	1879-0267
ISSN	0020-1383
DOI	10.1016/j.injury.2008.10.004
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