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  1. Article ; Online: Res-SE-ConvNet: A Deep Neural Network for Hypoxemia Severity Prediction for Hospital In-Patients Using Photoplethysmograph Signal.

    Mahmud, Talha Ibn / Imran, Sheikh Asif / Shahnaz, Celia

    IEEE journal of translational engineering in health and medicine

    2022  Volume 10, Page(s) 4901409

    Abstract: Determining the severity level of hypoxemia, the scarcity of saturated oxygen (SpO2) in the human body, is very important for the patients, a matter which has become even more significant during the outbreak of Covid-19 variants. Although the widespread ... ...

    Abstract Determining the severity level of hypoxemia, the scarcity of saturated oxygen (SpO2) in the human body, is very important for the patients, a matter which has become even more significant during the outbreak of Covid-19 variants. Although the widespread usage of Pulse Oximeter has helped the doctors aware of the current level of SpO2 and thereby determine the hypoxemia severity of a particular patient, the high sensitivity of the device can lead to the desensitization of the care-givers, resulting in slower response to actual hypoxemia event. There has been research conducted for the detection of severity level using various parameters and bio-signals and feeding them in a machine learning algorithm. However, in this paper, we have proposed a new residual-squeeze-excitation-attention based convolutional network (Res-SE-ConvNet) using only Photoplethysmography (PPG) signal for the comfortability of the patient. Unlike the other methods, the proposed method has outperformed the standard state-of-art methods as the result shows 96.5% accuracy in determining 3 class severity problems with 0.79 Cohen Kappa score. This method has the potential to aid the patients in receiving the benefit of an automatic and faster clinical decision support system, thus handling the severity of hypoxemia.
    MeSH term(s) Humans ; Photoplethysmography ; COVID-19/diagnosis ; SARS-CoV-2 ; Neural Networks, Computer ; Oxygen ; Hypoxia/diagnosis ; Hospitals
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2022-10-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2696555-0
    ISSN 2168-2372 ; 2168-2372
    ISSN (online) 2168-2372
    ISSN 2168-2372
    DOI 10.1109/JTEHM.2022.3217428
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: COVID-19: Management.

    Mahmud, Talha / Ansarie, Mosavir

    JPMA. The Journal of the Pakistan Medical Association

    2020  Volume 70Suppl 3, Issue 5, Page(s) S64–S68

    Abstract: Coronavirus disease (COVID-19) has grasped the world including Pakistan. Clinical features of this disease are variable, ranging from asymptomatic to critical disease. In this unprecedented global war, the Pakistan Chest Society has written a guideline ... ...

    Abstract Coronavirus disease (COVID-19) has grasped the world including Pakistan. Clinical features of this disease are variable, ranging from asymptomatic to critical disease. In this unprecedented global war, the Pakistan Chest Society has written a guideline for quick review for the specialists providing care to suspected or confirmed patients. This review highlights the approach to a patient with COVID-19, including definition of the various syndromes of the disease, the abnormal laboratory parameters and outlines the therapeutic measures which are currently under investigation.
    MeSH term(s) Antiviral Agents/adverse effects ; Antiviral Agents/therapeutic use ; Betacoronavirus ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Coronavirus Infections/drug therapy ; Coronavirus Infections/therapy ; Humans ; Monitoring, Physiologic ; Pakistan ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/therapy ; Practice Guidelines as Topic ; Respiratory Distress Syndrome, Adult ; Sepsis
    Chemical Substances Antiviral Agents
    Keywords covid19
    Language English
    Publishing date 2020-06-09
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 603873-6
    ISSN 0030-9982
    ISSN 0030-9982
    DOI 10.5455/JPMA.13
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Pulmonary embolism, thrombocytopenia, and antiphospholipid syndrome.

    Mahmud, Talha

    Journal of Ayub Medical College, Abbottabad : JAMC

    2011  Volume 23, Issue 4, Page(s) 138–141

    Abstract: This case report describes a young non-smoker male masquerading under the diagnosis of community acquired pneumonia who was found to have respiratory symptoms attributed to bilateral pulmonary emboli. There was also evidence of thrombocytopenia and ... ...

    Abstract This case report describes a young non-smoker male masquerading under the diagnosis of community acquired pneumonia who was found to have respiratory symptoms attributed to bilateral pulmonary emboli. There was also evidence of thrombocytopenia and proximal deep venous thrombosis of right lower limb. He underwent further investigations and was found to have positive anti-cardiolipin antibodies, lupus anticoagulant and prolonged activated partial thromboplastin time due to antiphospholipid antibody syndrome. This article highlights the importance of consideration of earlier diagnosis in younger patients with congenital thrombophilias that carries potential for prevention and treatment of life threatening thromboembolic manifestations.
    MeSH term(s) Anticoagulants/therapeutic use ; Antiphospholipid Syndrome/complications ; Antiphospholipid Syndrome/diagnosis ; Antiphospholipid Syndrome/drug therapy ; Diagnosis, Differential ; Humans ; Male ; Positron-Emission Tomography ; Pulmonary Embolism/complications ; Pulmonary Embolism/diagnosis ; Pulmonary Embolism/drug therapy ; Radiography, Thoracic ; Thrombocytopenia/complications ; Thrombocytopenia/diagnosis ; Thrombocytopenia/drug therapy ; Tomography, X-Ray Computed ; Ultrasonography, Doppler ; Young Adult
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2011-10
    Publishing country Pakistan
    Document type Case Reports ; Journal Article
    ZDB-ID 2192473-9
    ISSN 1025-9589
    ISSN 1025-9589
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: COVID-19: Management

    Mahmud, Talha / Ansarie, Mosavir

    J Pak Med Assoc

    Abstract: Coronavirus disease (COVID-19) has grasped the world including Pakistan. Clinical features of this disease are variable, ranging from asymptomatic to critical disease. In this unprecedented global war, the Pakistan Chest Society has written a guideline ... ...

    Abstract Coronavirus disease (COVID-19) has grasped the world including Pakistan. Clinical features of this disease are variable, ranging from asymptomatic to critical disease. In this unprecedented global war, the Pakistan Chest Society has written a guideline for quick review for the specialists providing care to suspected or confirmed patients. This review highlights the approach to a patient with COVID-19, including definition of the various syndromes of the disease, the abnormal laboratory parameters and outlines the therapeutic measures which are currently under investigation.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #32515388
    Database COVID19

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  5. Article: An AIDS patient with multiple opportunistic infections.

    Mahmud, Talha

    Journal of Ayub Medical College, Abbottabad : JAMC

    2010  Volume 22, Issue 2, Page(s) 210–213

    Abstract: A patient was diagnosed having advanced acquired immunodeficiency syndrome (AIDS) who suffered from various pulmonary and extrapulmonary infective complications. A number of opportunistic infections were diagnosed and prompt treatment was initiated. Due ... ...

    Abstract A patient was diagnosed having advanced acquired immunodeficiency syndrome (AIDS) who suffered from various pulmonary and extrapulmonary infective complications. A number of opportunistic infections were diagnosed and prompt treatment was initiated. Due to his low CD4+ lymphocyte count that carries a higher morbidity and mortality, he experienced clinical worsening even with treatment and could not survive through this Black Death.
    MeSH term(s) AIDS-Related Opportunistic Infections/diagnosis ; AIDS-Related Opportunistic Infections/microbiology ; AIDS-Related Opportunistic Infections/therapy ; Humans ; Male ; Middle Aged
    Language English
    Publishing date 2010-04
    Publishing country Pakistan
    Document type Case Reports ; Journal Article
    ZDB-ID 2192473-9
    ISSN 1025-9589
    ISSN 1025-9589
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Intractable cough due to endobronchial chondroma.

    Mahmud, Talha / Nasim, Zanobia / Saqib, Muhammad / Fatima, Saira

    Respiratory medicine case reports

    2019  Volume 29, Page(s) 100968

    Abstract: A 62-year-old man, suffering from bronchial asthma was evaluated due to intractable cough. His dyspnea was controlled but cough remained unresponsive to escalation of asthma management steps. Cough occurred in bouts, especially during night time and was ... ...

    Abstract A 62-year-old man, suffering from bronchial asthma was evaluated due to intractable cough. His dyspnea was controlled but cough remained unresponsive to escalation of asthma management steps. Cough occurred in bouts, especially during night time and was occasionally productive of mucoid sputum. Other than bilateral rhonchi on chest auscultation, remaining systemic examination was unremarkable. CT chest showed a mass lesion in the bronchus intermedius that was confirmed on bronchoscopy and was removed after electrocautery snare excision. Histopathology of the lesion was consistent with endobronchial chondroma. The patient experienced a dramatic resolution of cough post tumor removal. Follow up bronchoscopy after 24 months revealed no tumor recurrence.
    Language English
    Publishing date 2019-11-14
    Publishing country England
    Document type Case Reports
    ZDB-ID 2666110-X
    ISSN 2213-0071
    ISSN 2213-0071
    DOI 10.1016/j.rmcr.2019.100968
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: S

    Alam, Md Jahin / Mohammad, Mir Sayeed / Hossain, Md Adnan Faisal / Showmik, Ishtiaque Ahmed / Raihan, Munshi Sanowar / Ahmed, Shahed / Mahmud, Talha Ibn

    Computers in biology and medicine

    2022  Volume 150, Page(s) 106148

    Abstract: Dermoscopic images ideally depict pigmentation attributes on the skin surface which is highly regarded in the medical community for detection of skin abnormality, disease or even cancer. The identification of such abnormality, however, requires trained ... ...

    Abstract Dermoscopic images ideally depict pigmentation attributes on the skin surface which is highly regarded in the medical community for detection of skin abnormality, disease or even cancer. The identification of such abnormality, however, requires trained eyes and accurate detection necessitates the process being time-intensive. As such, computerized detection schemes have become quite an essential, especially schemes which adopt deep learning tactics. In this paper, a convolutional deep neural network, S
    MeSH term(s) Humans ; Dermoscopy/methods ; Skin Neoplasms/diagnostic imaging ; Neural Networks, Computer ; Skin/diagnostic imaging ; Image Processing, Computer-Assisted/methods
    Language English
    Publishing date 2022-09-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 127557-4
    ISSN 1879-0534 ; 0010-4825
    ISSN (online) 1879-0534
    ISSN 0010-4825
    DOI 10.1016/j.compbiomed.2022.106148
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Co-existent Ascariasis and Multiloculated Tuberculous Pleurisy Treated with Intrapleural Streptokinase.

    Mahmud, Talha / Naeem, Omer Muhammad

    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

    2015  Volume 25 Suppl 2, Page(s) S105–7

    Abstract: This case describes a young male with pleuro-pulmonary tuberculosis having one-week history of fever and hemoptysis along with a multiloculated right sided exudative lymphocytic pleural effusion. His pulmonary diagnostic confusion was due to passage of ... ...

    Abstract This case describes a young male with pleuro-pulmonary tuberculosis having one-week history of fever and hemoptysis along with a multiloculated right sided exudative lymphocytic pleural effusion. His pulmonary diagnostic confusion was due to passage of adult Ascaris lumbricoides per orally but that was found to be of intestinal origin. Pleural tissue histopathology revealed necrotizing granulomatous inflammation and right upper lobe bronchial washings were positive for acid fast bacilli. His multiloculated pleural effusion was successfully resolved with intrapleural streptokinase injections via a 10 French pleural catheter. Treatment with class-I anti-tuberculous drugs led to complete clearance of remaining pleuro-pulmonary shadowing.
    MeSH term(s) Adolescent ; Ascariasis/diagnosis ; Ascariasis/drug therapy ; Coinfection/diagnosis ; Coinfection/drug therapy ; Fibrinolytic Agents/therapeutic use ; Humans ; Male ; Pleural Effusion/drug therapy ; Streptokinase/administration & dosage ; Treatment Outcome ; Tuberculosis, Pleural/diagnosis ; Tuberculosis, Pleural/drug therapy
    Chemical Substances Fibrinolytic Agents ; Streptokinase (EC 3.4.-)
    Language English
    Publishing date 2015-10
    Publishing country Pakistan
    Document type Case Reports ; Journal Article
    ZDB-ID 2276646-7
    ISSN 1681-7168 ; 1022-386X
    ISSN (online) 1681-7168
    ISSN 1022-386X
    DOI 10.2015/JCPSP.S105S107
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: National Registry of Interstitial Lung Disease from Pakistan.

    Zubairi, Ali Bin Sarwar / Ansarie, Mosavir / Mahmud, Talha / Ashraf, Saadia / Rao, Nisar Ahmed / Javaid, Arshad / Shaheen, Zubair / Khan, Shereen / Khan, Afzaalullah

    Cureus

    2021  Volume 13, Issue 4, Page(s) e14684

    Abstract: Introduction Interstitial lung disease (ILD) is a heterogeneous group of over 200 parenchymal lung diseases with a myriad of etiologies. Interstitial lung disease registries from around the world show varying prevalence and incidence of these diseases. ... ...

    Abstract Introduction Interstitial lung disease (ILD) is a heterogeneous group of over 200 parenchymal lung diseases with a myriad of etiologies. Interstitial lung disease registries from around the world show varying prevalence and incidence of these diseases. The aim of this study was to determine the epidemiology and characteristics of ILD in Pakistan. Methods This web-based registry, which is the first multicenter registry of ILD from Pakistan, recruited patients from 10 centers of five major cities between January 2016 and March 2019. Results A total of 744 patients were enrolled in the registry. The five most frequent ILDs were idiopathic pulmonary fibrosis (IPF) 34.4%, hypersensitivity pneumonitis (HP) - 17.7%, idiopathic nonspecific interstitial pneumonitis (iNSIP) - 16.8%, connective tissue disease-associated ILD (CTD-ILD) - 16.3%, and sarcoidosis - 9.1%. Conclusion Idiopathic pulmonary fibrosis is the most prevalent ILD in Pakistan, followed by HP and iNSIP. An ongoing prospective registry with longitudinal follow-up will help us further elaborate on the clinical characteristics, treatment, and survival outcome of patients with ILD.
    Language English
    Publishing date 2021-04-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.14684
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Simulation training using cadaver sheep chest in pleuroscopy - A step towards skills enhancement.

    Mahmud, Talha / Nasir, Tajwar / Saqib, Muhammad / Aasim, Muhammad / Siddique, Nasir

    JPMA. The Journal of the Pakistan Medical Association

    2017  Volume 67, Issue 4, Page(s) 552–555

    Abstract: Objective: For assessing the use of if simulation training on animal cadavers as a useful tool for training in pleuroscopy.: Methods: The email-based cross-sectional study was conducted in December 2014 at Shaikh Zayed Hospital, Federal Postgraduate ... ...

    Abstract Objective: For assessing the use of if simulation training on animal cadavers as a useful tool for training in pleuroscopy.
    Methods: The email-based cross-sectional study was conducted in December 2014 at Shaikh Zayed Hospital, Federal Postgraduate Medical Institute, Lahore, Pakistan, and comprised respiratory physicians and trainees after their participation in a two-day hands-on training course on pleuroscopy and pleural medical procedures. The responses were analysed and the responses of physicians and trainees were compared.
    Results: Of the 44 individuals who attended the course and were contacted through emails, 38(86.4%) responded, including 20(52.6%) physicians and 18(47.3%) trainees. All the 38(100%) subjects uniformly accepted the utility of simulation training in enhancing education, improving skill, and improving confidence by repeated practice, and felt that the inclusion of animal models for learning fundamental pleuroscopic procedures can help a lot in teaching.
    Conclusions: Animal cadavers can be used as an effective teaching tool for pleuroscopy training.
    MeSH term(s) Animals ; Cadaver ; Humans ; Pulmonary Medicine/education ; Sheep ; Simulation Training/methods ; Thoracoscopy/education
    Language English
    Publishing date 2017-08-24
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 603873-6
    ISSN 0030-9982
    ISSN 0030-9982
    Database MEDical Literature Analysis and Retrieval System OnLINE

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