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  1. Article ; Online: Knowledge and Attitudes of Sexually Transmitted Infections Among High School Students in Sarajevo.

    Mahmutovic Vranic, Sabina / Aljicevic, Mufida / Segalo, Sabina / Joguncic, Anes

    Acta medica academica

    2019  Volume 48, Issue 2, Page(s) 147–158

    Abstract: Objective: The aim of the study was to evaluate knowledge and behavioural risks related to sexually transmitted infection (STIs) among high school students.: Methods: The cross sectional study was conducted among students aged 15-18 years old from ... ...

    Abstract Objective: The aim of the study was to evaluate knowledge and behavioural risks related to sexually transmitted infection (STIs) among high school students.
    Methods: The cross sectional study was conducted among students aged 15-18 years old from two high schools in the Sarajevo Canton in the period from October 2017 to March 2018. An anonymous self-administered questionnaire was used. The survey investigated their socio-demographic characteristics, sexual habits and level of knowledge about STIs. The data were analysed using SPSS version 25 and MS Excel 2016.
    Results: In total 278 high school students participated in the study, with a mean age of 17.79±1.026 years, of which 89 (32%) were male, and 189 (68%) were female. There was no significant difference in age in relation to sex distribution (P=0.074). Regarding the number of participants, 234 (84.2%) were from the dental school, while 44 (15.8%) were from a gimnazija (grammar high school). There was no significant difference in gender-based distribution by school (P=0.080). Students from the grammar high school had significantly better knowledge about the impact of STI on the foetus (P=0.025) and infected individuals (P=0.001), also about the impact of STI on sterility (P=0.005).
    Conclusion: Our study confirmed the need for implementation of sexual education programs in the final grades of elementary school or in first grades of high school, aimed at improving knowledge of sexually transmitted infections and improving sexual and reproductive health.
    MeSH term(s) Adolescent ; Bosnia and Herzegovina ; Cigarette Smoking ; Coitus ; Cross-Sectional Studies ; Female ; Health Knowledge, Attitudes, Practice ; Humans ; Male ; Menarche/physiology ; Sexual Behavior ; Sexual Partners ; Sexually Transmitted Diseases/psychology ; Socioeconomic Factors ; Surveys and Questionnaires ; Underage Drinking
    Language English
    Publishing date 2019-11-11
    Publishing country Bosnia and Herzegovina
    Document type Journal Article ; Multicenter Study
    ZDB-ID 2558604-X
    ISSN 1840-2879 ; 1840-1848
    ISSN (online) 1840-2879
    ISSN 1840-1848
    DOI 10.5644/ama2006-124.253
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Panton-Valentine leukocidin and staphylococcal cassette chromosome mec characterization of community acquired methicillin-resistant Staphylococcus aureus.

    Rebić, Velma / Budimir, Ana / Aljicević, Mufida / Mahmutović Vranić, Sabina / Rebić, Damir

    Central European journal of public health

    2019  Volume 27, Issue 1, Page(s) 58–63

    Abstract: Objectives: Staphylococcus aureus (SA) represents one of the most important microorganism that is part of the normal microflora of humans, but in certain conditions can cause very serious infections. Methicillin-resistant Staphylococcus aureus (MRSA) is ...

    Abstract Objectives: Staphylococcus aureus (SA) represents one of the most important microorganism that is part of the normal microflora of humans, but in certain conditions can cause very serious infections. Methicillin-resistant Staphylococcus aureus (MRSA) is responsible for a wide spectrum of nosocomial and community associated infections worldwide. The aim of this study was to determine community acquired MRSA (CA-MRSA), as well as the frequency of Panton-Valentine leukocidin (PVL) genes and staphylococcal cassette chromosome mec (SCCmec) types in isolates obtained from outpatients in the region of 700,000 people (Canton Sarajevo, Bosnia and Herzegovina) Methods: Our investigation included phenotypic and genotypic markers such as antimicrobial resistance, pulsed-field gel electrophoresis (PFGE), SCC typing, and PVL detection.
    Results: Antimicrobial susceptibility: all MRSA isolates were resistant to the β-lactam antibiotics tested, and all isolates were susceptible to trimethoprim sulphamethoxazole, rifampicin, fusidic acid, linezolid, and vancomycin. After the PFGE analysis, the isolates were grouped into five similarity groups: A-E. The largest number of isolates belonged to one of two groups: C - 60% and D - 27%. In both groups C and D, SCCmec type IV was predominant (60% and 88.8%, respectively). A total of 24% of the isolates had positive expression of PVL genes, while 76% showed a statistically significantly greater negative expression of PVL genes.
    Conclusions: Using combination techniques, we were able to investigate the origin and genetic background of the strains. PFGE analysis revealed two large, genetically related groups of strains consisting of 87 isolates. Our results suggest failure to apply the screening policy, and a lack of knowledge about multiresistant MRSA strains. This study showed the local epidemiological situation which should be the basis of antimicrobial empiric therapy for non-hospitalized patients.
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Bacterial Proteins ; Bacterial Toxins/genetics ; Bosnia and Herzegovina/epidemiology ; Chromosomes ; Community-Acquired Infections/epidemiology ; Community-Acquired Infections/microbiology ; Exotoxins/genetics ; Humans ; Leukocidins/genetics ; Methicillin ; Methicillin-Resistant Staphylococcus aureus/drug effects ; Methicillin-Resistant Staphylococcus aureus/genetics ; Methicillin-Resistant Staphylococcus aureus/isolation & purification ; Microbial Sensitivity Tests ; Penicillin-Binding Proteins ; Staphylococcal Infections/epidemiology ; Staphylococcal Infections/microbiology
    Chemical Substances Anti-Bacterial Agents ; Bacterial Proteins ; Bacterial Toxins ; Exotoxins ; Leukocidins ; Panton-Valentine leukocidin ; Penicillin-Binding Proteins ; mecA protein, Staphylococcus aureus ; Methicillin (Q91FH1328A)
    Language English
    Publishing date 2019-03-29
    Publishing country Czech Republic
    Document type Journal Article
    ZDB-ID 1176053-9
    ISSN 1803-1048 ; 1210-7778 ; 0022-1732
    ISSN (online) 1803-1048
    ISSN 1210-7778 ; 0022-1732
    DOI 10.21101/cejph.a4979
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4008: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article: Staphylococcus aureus carriage among medical students.

    Mahmutović Vranić, Sabina / Puškar, Mediha

    Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina

    2012  Volume 9, Issue 2, Page(s) 325–329

    Abstract: Aim: To investigate the frequency of S. aureus isolation from the nose among students in relation to age, gender, and year of the study.: Methods: A retrospective study included 387 students who performed sanitary examination at the Department of ... ...

    Abstract Aim: To investigate the frequency of S. aureus isolation from the nose among students in relation to age, gender, and year of the study.
    Methods: A retrospective study included 387 students who performed sanitary examination at the Department of Microbiology, School of Medicine, University of Sarajevo. The bacterial strains were identified by conventional method and the antibiotic resistance was carried out by disc diffusion method.
    Results: The overall carriage rate of Staphylococcus aureus was 10.6%. S. aureus were isolated in 58.54% female and 41.46% male students (p more than 0.05). S. aureus was isolated in 22 (10.8%) in the age group 22-26, and in 17 (10.2%) students in the age group 27-32 The lowest prevalence of isolates was in the 33-38 age group, with only two (12.5%) (p more than 0.05). According to the year of the study, the greatest number of S. aureus strains was present in the fourth year, 21 (14.5%), while the smallest one was in the sixth year, 4 (3.3%).
    Conclusion: No significant differences were found in the frequency of isolates in relation to age and gender of students, but it was found in relation to the year of the study. The study identifies the importance of medical students as possible agents of transmission in the hospital environment.
    MeSH term(s) Adult ; Carrier State/microbiology ; Female ; Humans ; Male ; Microbial Sensitivity Tests ; Nasal Cavity/microbiology ; Staphylococcus aureus/drug effects ; Staphylococcus aureus/isolation & purification ; Students, Medical ; Young Adult
    Language English
    Publishing date 2012-08
    Publishing country Bosnia and Herzegovina
    Document type Journal Article
    ZDB-ID 2378942-6
    ISSN 1840-2445 ; 1840-0132
    ISSN (online) 1840-2445
    ISSN 1840-0132
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Detection of mycoplasma genitalium in female cervical samples by multitarget real-time PCR.

    Mahmutović-Vranić, Sabina / Beslagić, Edina / Hardick, Justin / Slaković, Maida / Gaydos, Charlotte A

    Bosnian journal of basic medical sciences

    2007  Volume 7, Issue 2, Page(s) 107–110

    Abstract: Mycoplasma genitalum (MG) is associated with variety of urogenital infections such as nongonococcal urethritis (NGU), endometritis and cervicitis. The objective of this study was to demonstrate and evaluate a research polymerase chain reaction (PCR) ... ...

    Abstract Mycoplasma genitalum (MG) is associated with variety of urogenital infections such as nongonococcal urethritis (NGU), endometritis and cervicitis. The objective of this study was to demonstrate and evaluate a research polymerase chain reaction (PCR) assay, for the detection of MG in cervical samples of a tested population of women attending gynecology clinics in Bosnia and Herzegovina. The Multitarget Real-Time (MTRT) PCR, utilizing the ABI 7900HT, the sequence detection system, was performed for the detection of MG. Cervical samples (N=97) from females were divided into three types of patient groups: Group 1: patients who had known abnormal clinical cytology reports (N=34); Group 2: patients who reported a history of genitourinary infections (N=22); and Group 3: patients not in either groups 1 or 2 (N=41). Overall, 14,43% (14/97) of those tested were positive for MG. A positive sample was defined as having a cycle threshold cross point (Ct) < 40,0 with a fluorescent detection comparable to the low positive control utilized during the run. This study validated the use of MTRT PCR as a reliable method for the detection of MG in clinical specimens and should facilitate large-scale screening for this organism.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Cervix Uteri/microbiology ; Cervix Uteri/pathology ; DNA, Bacterial/genetics ; False Positive Reactions ; Female ; Humans ; Mass Screening/methods ; Middle Aged ; Mycoplasma Infections/diagnosis ; Mycoplasma Infections/pathology ; Mycoplasma genitalium/genetics ; Polymerase Chain Reaction/methods ; Sensitivity and Specificity
    Chemical Substances DNA, Bacterial
    Language English
    Publishing date 2007-05
    Publishing country Bosnia and Herzegovina
    Document type Evaluation Studies ; Journal Article
    ZDB-ID 2240029-1
    ISSN 1512-8601
    ISSN 1512-8601
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6314: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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