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  1. Book ; Online ; Thesis: Cardiovascular risk assessment and biopsychological effects of acute and repeated social stress in German soldiers

    Maier, Tanja [Verfasser]

    2024  

    Author's details Tanja Maier
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language English
    Publisher Universität Ulm
    Publishing place Ulm
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

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  2. Book ; Online: Gender und Fernsehen : Perspektiven einer kritischen Medienwissenschaft

    Maier, Tanja

    2007  

    Keywords Art forms ; Gender ; Medien ; Kultur ; Fernsehen ; Geschlecht ; Medienästhetik ; Cultural Studies ; Medienwissenschaft ; Media ; Culture ; Television ; Media Aesthetics ; Media Studies
    Size 1 electronic resource (280 pages)
    Publisher transcript Verlag
    Publishing place Bielefeld
    Document type Book ; Online
    Note German ; Open Access
    HBZ-ID HT021028563
    ISBN 9783899426892 ; 3899426894
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Thesis: Die Bedeutung zentraler oxytocinerger Neurone bei der Vermittlung der kardiovaskulären Reaktionen und der Verhaltensantwort auf Substanz P im Gehirn der Ratte

    Maier, Tanja

    2004  

    Author's details vorgelegt von Tanja Maier
    Language German
    Size 79 S. : Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Kiel, Univ., Diss., 2004
    HBZ-ID HT014074850
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2004 D 333 order for loan Magazin

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  4. Article ; Online: Equivalence study of extractables from single-use biopharmaceutical manufacturing equipment after X-ray or gamma irradiation.

    Menzel, Roberto / Pahl, Ina / Dorey, Samuel / Maier, Tanja / Hauk, Armin

    International journal of pharmaceutics

    2023  Volume 634, Page(s) 122677

    Abstract: Single-use (SU) devices and assemblies used as manufacturing equipment in the biopharmaceutical industry require comprehensive qualifications. These qualifications include the assessment of compounds released from SU devices in contact with the process ... ...

    Abstract Single-use (SU) devices and assemblies used as manufacturing equipment in the biopharmaceutical industry require comprehensive qualifications. These qualifications include the assessment of compounds released from SU devices in contact with the process fluids, and how these leachable compounds potentially influence process performance, drug product quality, and patient safety. SU suppliers need to provide comprehensive qualification data for several parameters, for both new products and product changes, such as changes in the sterilization process applied to the SU device. The introduction of X-ray irradiation as an alternative to the currently used and established gamma irradiation of SU devices represents a situation where robust data is required to demonstrate equivalency between these two radiation technologies. Here, we present the results of a comprehensive extractables study for three SU components, bags, tubing, and sterilizing grade filters, evaluated after X-ray and gamma-ray irradiation. The selected study conditions were set up to allow a direct comparison of the results from the two sterilization methods, and to allow conclusions to be made on the impact of irradiation type on the polymers and their additives. Orthogonal analytical methods are applied to identify and quantify all organic compounds present. The data package provided here supports risk assessments for application of irradiated SU equipment in biopharmaceutical manufacturing. The formation of reaction products and the fundamental chemical pathways are discussed and found to be independent of the irradiation type. The results demonstrate the equivalency of both irradiation methods for extractables from plastic components used in pharmaceutical and biopharmaceutical manufacturing.
    MeSH term(s) Humans ; Biological Products ; X-Rays ; Plastics ; Polymers/chemistry ; Organic Chemicals ; Drug Contamination ; Drug Packaging ; Pharmaceutical Preparations
    Chemical Substances Biological Products ; Plastics ; Polymers ; Organic Chemicals ; Pharmaceutical Preparations
    Language English
    Publishing date 2023-02-03
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 428962-6
    ISSN 1873-3476 ; 0378-5173
    ISSN (online) 1873-3476
    ISSN 0378-5173
    DOI 10.1016/j.ijpharm.2023.122677
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1409: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Gemeinsam besser werden. Beschaffungscontrolling

    Maier, Tanja

    Führen und Wirtschaften im Krankenhaus

    2017  Volume 34, Issue 5, Page(s) 450

    Language German
    Document type Article
    ZDB-ID 605756-1
    ISSN 0175-4548
    Database Current Contents Medicine

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1949: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Dimethylsilanediol from silicone elastomers: Analysis, release from biopharmaceutical process equipment, and clearance studies.

    Menzel, Roberto / Korzun, André / Golz, Christopher / Maier, Tanja / Pahl, Ina / Hauk, Armin

    International journal of pharmaceutics

    2023  Volume 646, Page(s) 123441

    Abstract: Polysiloxanes are considered one of the most important commercial families of synthetic elastomers. They are frequently employed in biopharmaceutical manufacturing equipment as flexible single-use solutions due to superior material properties and ... ...

    Abstract Polysiloxanes are considered one of the most important commercial families of synthetic elastomers. They are frequently employed in biopharmaceutical manufacturing equipment as flexible single-use solutions due to superior material properties and compatibility with diverse sterilization methods. Extractables and leachables (E&L) testing is essential in qualifying such equipment, involving extraction studies to assess the potential release of compounds from plastic components for risk assessment. Silicone releases oligomeric siloxanes and small hydrolysis products, with dimethylsilanediol (DMSD) being the main hydrolysis product found in significant concentrations in aqueous process solutions. DMSD presents challenges for analysis, requiring specifically tailored analytical methods to detect it, which are commonly not applied in standard E&L screening tests. In biopharmaceutical manufacturing, it is relevant to consider the potential of DMSD to repolymerize into silicone oil when specific process parameters are altered. This may lead to interactions with drug ingredients, including proteins, resulting in the formation of aggregates. We synthesized and characterized DMSD using X-ray structure analysis and established an HPLC method with a refractive index detector to investigate the release of DMSD from commercially available silicone tubing used in drug manufacturing following autoclaving and irradiation. Subsequently, we assessed typical biopharmaceutical downstream operations for effectively removing this compound from the process stream.
    Language English
    Publishing date 2023-09-27
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 428962-6
    ISSN 1873-3476 ; 0378-5173
    ISSN (online) 1873-3476
    ISSN 0378-5173
    DOI 10.1016/j.ijpharm.2023.123441
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1409: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Book: Medien, Öffentlichkeit und Geschlecht in Bewegung

    Maier, Tanja

    Forschungsperspektiven der kommunikations- und medienwissenschaftlichen Geschlechterforschung

    (Critical media studies ; 8)

    2012  

    Title variant kommunikationswissenschaftlichen
    Author's details Tanja Maier ... (Hg.)
    Series title Critical media studies ; 8
    Keywords Communication/Social aspects ; Mass media/Social aspects ; Mass media and public opinion ; Mass media and sex ; Sex differences in mass media ; Sex role in mass media ; Geschlechtsunterschied ; Kommunikationswissenschaft ; Sozialer Wandel ; Öffentlichkeit ; Massenmedien ; Geschlechterforschung ; Soziale Konstruktion
    Language German
    Size 213 S., Ill., 22 cm
    Publisher Transcript
    Publishing place Bielefeld
    Document type Book
    Note Literaturangaben
    ISBN 3837619176 ; 9783837619171
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  8. Book: Medien, Öffentlichkeit und Geschlecht in Bewegung

    Maier, Tanja

    Forschungsperspektiven der kommunikations- und medienwissenschaftlichen Geschlechterforschung

    (Critical media studies ; 8)

    2012  

    Title variant kommunikationswissenschaftlichen
    Author's details Tanja Maier ... (Hg.)
    Series title Critical media studies ; 8
    Keywords Communication/Social aspects ; Mass media/Social aspects ; Mass media and public opinion ; Mass media and sex ; Sex differences in mass media ; Sex role in mass media ; Geschlechtsunterschied ; Kommunikationswissenschaft ; Sozialer Wandel ; Öffentlichkeit ; Massenmedien ; Geschlechterforschung ; Soziale Konstruktion
    Language German
    Size 213 S., Ill., 22 cm
    Publisher Transcript
    Publishing place Bielefeld
    Document type Book
    Note Literaturangaben
    ISBN 3837619176 ; 9783837619171
    Database Former special subject collection: coastal and deep sea fishing

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  9. Article ; Online: X-ray sterilization of biopharmaceutical manufacturing equipment-Extractables profile of a film material and copolyester Tritan™ compared to gamma irradiation.

    Menzel, Roberto / Dorey, Samuel / Maier, Tanja / Pahl, Ina / Hauk, Armin

    Biotechnology progress

    2021  Volume 38, Issue 1, Page(s) e3214

    Abstract: The biopharmaceutical industry gains enormous flexibility in production processes by using sterilized preassembled single-use devices. Gamma irradiation is an established sterilization technology that may be restricted in the future by the availability ... ...

    Abstract The biopharmaceutical industry gains enormous flexibility in production processes by using sterilized preassembled single-use devices. Gamma irradiation is an established sterilization technology that may be restricted in the future by the availability of
    MeSH term(s) Biological Products ; Polymers ; Sterilization/methods ; X-Rays
    Chemical Substances Biological Products ; Polymers
    Language English
    Publishing date 2021-10-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 165657-0
    ISSN 1520-6033 ; 8756-7938
    ISSN (online) 1520-6033
    ISSN 8756-7938
    DOI 10.1002/btpr.3214
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4253: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Book ; Online: At the Top?

    Maier, Tanja

    mediale Bilder von Personen in Spitzenpositionen der Wissenschaft und Wirtschaft

    (Discussion paper / Wissenschaftszentrum Berlin für Sozialforschung, Forschungsschwerpunkt Gesellschaft und wirtschaftliche Dynamik, Forschungsgruppe Wissenschaftspolitik ; SP III 2013-601)

    2013  

    Abstract: As only few people are in personal contact with leaders in professional organisations of science and the economy, the media plays a central role in communicating scientific and economic issues. Consequently, a great share of public knowledge about ... ...

    Author's details Tanja Maier
    Series title Discussion paper / Wissenschaftszentrum Berlin für Sozialforschung, Forschungsschwerpunkt Gesellschaft und wirtschaftliche Dynamik, Forschungsgruppe Wissenschaftspolitik ; SP III 2013-601
    Abstract As only few people are in personal contact with leaders in professional organisations of science and the economy, the media plays a central role in communicating scientific and economic issues. Consequently, a great share of public knowledge about successful scientists and managers develops on the basis of information provided on a daily basis by journalists. This study thus inquires about the ways in which media representatives portray and problematize leaders in science and the economy. This includes particularly a comparison between the two sectors as well as between gender groups. The study consists of a qualitative discourse analysis of print media articles about leaders in science and the economy in the following newpapers and magazines: FRANKFURTER ALLGEMEINE ZEITUNG, SÜDDEUTSCHE ZEITUNG, DIE TAGESZEITUNG, DIE ZEIT, DER SPIEGEL, FOCUS, CAPITAL, MANAGER MAGAZIN, BILD DER WISSENSCHAFT und SPEKTRUM DER WISSENSCHAFT. This evaluation was conducted over a period of seven months in 2008. In discussing the results of the study, this paper adopts a deconstructive approach to gender studies and frames the discussion on journalism from a cultural perspective.

    Wissen über wissenschaftliche und wirtschaftliche Sachverhalte ist auch medial vermittelt. Nur die wenigsten Menschen haben persönliche Kontakte mit Personen, die in Spitzenpositionen von Wissenschafts- oder Wirtschaftsorganisationen tätig sind. Für große Teile der Öffentlichkeit entsteht das Wissen über erfolgreiche WissenschaftlerInnen und ManagerInnen auf der Grundlage von medialen Repräsentationen, die ihnen der Journalismus täglich zur Verfügung stellt. Die vorliegende Studie fragt danach, wie die Presseberichterstattung Personen in Spitzenpositionen der Wissenschaft und Wirtschaft porträtiert und problematisiert. Dabei werden Vergleiche sowohl zwischen Wissenschaft und Wirtschaft als auch zwischen den Geschlechtern vorgenommen. Die Studie basiert auf einer qualitativen Textanalyse von Printmedien, die sich an der sozialwissenschaftli-chen Diskursanalyse orientiert. Gegenstand der Untersuchung sind Artikel über Personen in Toppositionen von Wissenschaft und Wirtschaft in folgenden Medien: FRANKFURTER ALLGEMEINE ZEITUNG, SÜDDEUTSCHE ZEITUNG, DIE TAGESZEITUNG, DIE ZEIT, DER SPIEGEL, FOCUS, CAPITAL, MANAGER MAGAZIN, BILD DER WISSENSCHAFT und SPEKTRUM DER WISSENSCHAFT. Der Untersuchungszeitraum erstreckt sich über sieben Monate im Jahr 2008. Die Befunde werden vor dem Hintergrund der dekonstruktiven medienwissenschaftlichen Geschlechterforschung und der kulturorientierten Journalismusforschung diskutiert.
    Language German
    Size Online-Ressource (III, 57 S.)
    Publisher WZB
    Publishing place Berlin
    Document type Book ; Online
    Note IMD-Felder maschinell generiert ; Zsfassung in engl. Sprache
    Database ECONomics Information System

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