Article ; Online: Vaccine effectiveness against influenza hospitalisation in adults during the 2022/2023 mixed season of influenza A(H1N1)pdm09, A(H3N2) and B circulation, Europe: VEBIS SARI VE hospital network.
Influenza and other respiratory viruses
2024 Volume 18, Issue 2, Page(s) e13255
Abstract: We conducted a multicentre hospital-based test-negative case-control study to measure vaccine effectiveness (VE) against PCR-confirmed influenza in adult patients with severe acute respiratory infection (SARI) during the 2022/2023 influenza season in ... ...
| Abstract | We conducted a multicentre hospital-based test-negative case-control study to measure vaccine effectiveness (VE) against PCR-confirmed influenza in adult patients with severe acute respiratory infection (SARI) during the 2022/2023 influenza season in Europe. Among 5547 SARI patients ≥18 years, 2963 (53%) were vaccinated against influenza. Overall VE against influenza A(H1N1)pdm09 was 11% (95% CI: -23-36); 20% (95% CI: -4-39) against A(H3N2) and 56% (95% CI: 22-75) against B. During the 2022/2023 season, while VE against hospitalisation with influenza B was >55%, it was ≤20% for influenza A subtypes. While influenza vaccination should be a priority for future seasons, improved vaccines against influenza are needed. |
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| MeSH term(s) | Adult ; Humans ; Influenza, Human/epidemiology ; Influenza, Human/prevention & control ; Seasons ; Influenza A Virus, H1N1 Subtype/genetics ; Influenza A Virus, H3N2 Subtype/genetics ; Case-Control Studies ; Vaccine Efficacy ; Influenza Vaccines ; Europe/epidemiology ; Hospitalization ; Hospitals ; Pneumonia ; Vaccination | |||||
| Chemical Substances | Influenza Vaccines | |||||
| Language | English | |||||
| Publishing date | 2024-02-23 | |||||
| Publishing country | England | |||||
| Document type | Journal Article | |||||
| ZDB-ID | 2274538-5 | |||||
| ISSN | 1750-2659 ; 1750-2640 | |||||
| ISSN (online) | 1750-2659 | |||||
| ISSN | 1750-2640 | |||||
| DOI | 10.1111/irv.13255 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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