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  1. Article ; Online: What is your count? An observational study of lymph node counting in 2,028 colorectal cancer resections.

    Srivastava, Shivali / Kak, Ipshita / Major, Pierre / Bonert, Michael

    PloS one

    2024  Volume 19, Issue 2, Page(s) e0295209

    Abstract: Background: Lymph node status and lymph node count (LNC) are predictors of colorectal cancer outcome. Under-sampling of lymph nodes may lead to clinically relevant stage migration.: Methods: Colorectal cancer (CRC) cases with a synoptic report, ... ...

    Abstract Background: Lymph node status and lymph node count (LNC) are predictors of colorectal cancer outcome. Under-sampling of lymph nodes may lead to clinically relevant stage migration.
    Methods: Colorectal cancer (CRC) cases with a synoptic report, accessioned 2012-2020 at a regional laboratory, were extracted and retrospectively studied. LNC, positive lymph node count (PLNC), tumour deposits present (TDpos), and 'y' (staging) prefix (YS) were retrieved and tabulated by pathologist using custom software. Statistical analyses were done with R.
    Data and results: The cohort had 2,543 CRC resections. Seventeen pathologists interpreted >50 cases (range: 56-356) each and collectively saw 2,074. After cases with unavailable data were purged, 2,028 cases remained with 43,996 lymph nodes, of which 2,637/43,996 were positive. 368 cases had a 'y' prefix, and 379 had TDpos. The 17 pathologists' median LNC/case was 19.0 (range: 14.0-24.0), and the mean PLNC per case was 1.4 (range: 1.0-2.0). Kruskal-Wallis rank sum tests showed there were differences in LNC (p<0.001) among pathologists; however, PLNC did not show this association (p = 0.2917). T-tests showed that mean LNC (p<0.001) and PLNC (p<0.035) differed between YS. 138 of 2,028 cases had less than the 12 LNC target. Logistic regression revealed a strong association between meeting the LNC target and pathologist (p<0.001) but TDpos was non-predictive (p = 0.4736).
    Conclusions: Positive lymph node call rate has a good consistency in the laboratory; however, lymph node count varies significantly between pathologists. Standardized counting criteria are needed to improve uniformity and could be aided by synoptic reporting data.
    MeSH term(s) Humans ; Lymph Node Excision ; Retrospective Studies ; Lymph Nodes/surgery ; Lymph Nodes/pathology ; Specimen Handling ; Colorectal Neoplasms/surgery ; Colorectal Neoplasms/pathology ; Neoplasm Staging
    Language English
    Publishing date 2024-02-08
    Publishing country United States
    Document type Observational Study ; Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0295209
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: First record of

    Juhásová, Ľ / Königová, A / Molnár, L / Major, P / Králová-Hromadová, I / Čisovská Bazsalovicsová, E

    Helminthologia

    2023  Volume 60, Issue 4, Page(s) 380–384

    Abstract: An injured young individual of the Eastern Imperial Eagle ( ...

    Abstract An injured young individual of the Eastern Imperial Eagle (
    Language English
    Publishing date 2023-12-31
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2056740-6
    ISSN 1336-9083 ; 0440-6605
    ISSN (online) 1336-9083
    ISSN 0440-6605
    DOI 10.2478/helm-2023-0032
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  3. Article ; Online: Current trends in bariatric surgery in patients older than 65 years in Poland.

    Dowgiałło-Gornowicz, Natalia / Jaworski, Paweł / Lech, Paweł / Major, Piotr

    Polski przeglad chirurgiczny

    2024  Volume 96, Issue 3, Page(s) 1–5

    Abstract: ... Introduction: ... It is already known that bariatric surgery can improve the health and quality of life of morbidly obese patients of all ages. Our population is getting older. That is why the number of bariatric surgeries among obese people over ... ...

    Abstract
    Introduction:
    It is already known that bariatric surgery can improve the health and quality of life of morbidly obese patients of all ages. Our population is getting older. That is why the number of bariatric surgeries among obese people over 65 years of age is systematically increasing.

    Aims:
    The study aims to analyze the management of patients over 65 years of age in Polish bariatric centers.

    Material and methods:
    The study was conducted on representatives from the 30 largest bariatric departments in Poland. By collecting surveys, we aimed to analyze changes in qualifications for surgery and care for elderly patients.

    Results:
    13 of 30 (43.3%) representatives responded to the survey. The remaining centers did not qualify patients over 65 years old for the surgical treatment of obesity. The mean percentage of patients over 65 who underwent bariatric surgery was 2.75. Most representatives (69.2%) chose SG as the procedure of choice in patients over 65 years of age. According to 84.6% of surgeons, age did not matter when qualifying patients over 65 years of age for BS. The majority of surgeons (53.8%) believed that bariatric surgery in older patients was comparable to the one in younger patients. Nine (69.2%) surgeons believed that there should be no age limit for bariatric surgery.

    Conclusions:
    Only almost half of the bariatric centers in Poland perform operations on patients over 65 years of age. Most Polish surgeons claim that operations on older and on younger patients have comparable benefits, and that there is no need for age limit.
    .
    MeSH term(s) Humans ; Poland ; Bariatric Surgery/statistics & numerical data ; Bariatric Surgery/trends ; Male ; Aged ; Female ; Obesity, Morbid/surgery ; Quality of Life
    Language English
    Publishing date 2024-05-09
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 128732-1
    ISSN 2299-2847 ; 0032-373X
    ISSN (online) 2299-2847
    ISSN 0032-373X
    DOI 10.5604/01.3001.0053.9871
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Are the European Society of Cardiology guidelines on lipid-lowering treatment implemented in morbidly obese patients qualified for bariatric surgery?

    Bylica, Jan / Major, Piotr / Grodzicki, Tomasz / Fornal, Maria

    Kardiologia polska

    2023  Volume 81, Issue 7-8, Page(s) 772–774

    MeSH term(s) Humans ; Obesity, Morbid/complications ; Obesity, Morbid/surgery ; Bariatric Surgery ; Treatment Outcome ; Cardiology ; Lipids
    Chemical Substances Lipids
    Language English
    Publishing date 2023-05-24
    Publishing country Poland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 411492-9
    ISSN 1897-4279 ; 0022-9032
    ISSN (online) 1897-4279
    ISSN 0022-9032
    DOI 10.33963/KP.a2023.0120
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Bariatric and Metabolic Surgery in Patients Older than 65 Years - a Multicenter Study.

    Dowgiałło-Gornowicz, Natalia / Lech, Paweł / Major, Piotr

    Obesity surgery

    2023  Volume 33, Issue 10, Page(s) 3106–3111

    Abstract: Introduction: With the increase in life expectancy and a growing number of people suffering from obesity, bariatric and metabolic surgery is becoming a major concern in the elderly population. The study aimed to collect, systematize and present the ... ...

    Abstract Introduction: With the increase in life expectancy and a growing number of people suffering from obesity, bariatric and metabolic surgery is becoming a major concern in the elderly population. The study aimed to collect, systematize and present the available data on the surgical treatment of obesity among Polish patients over 65 years of age.
    Material and methods: A retrospective study analysed patients over 65 years who underwent laparoscopic bariatric procedures in Poland from 2008 to 2022. The efficacy endpoints were percentage of excess weight loss (EWL%), percentage of total weight loss (%TWL), improvement in obesity-related diseases.
    Results: The group consisted of 284 patients (173 women, 60.9%). The mean follow-up was 47.5 months. The mean BMI before surgery was 43.1 kg/m2. 146 (51.4%) patients had T2D, and 244 (85.9%) had HT. The most common procedure was sleeve gastrectomy (82.0%). The mean EWL% after surgery was 50.9%, and the mean TWL% after surgery was 20.6%. There was the statistically significant difference between AGB vs OAGB, SG vs OAGB in %EWL (p = 0.0116, p = 0.009, respectively) and RYGB vs OAGB in %TWL (p = 0.0291). After surgery, 93 patients (63.7%) had complete or partial remission of T2D, and 112 patients (45.9%) had complete or partial remission of HT.
    Conclusion: Bariatric surgery appears to be a safe and effective method of treatment of obesity in patients over 65 years of age. OAGB seems to have better results in weight loss than SG, RYGB, and AGB in older patients.
    MeSH term(s) Humans ; Female ; Aged ; Obesity, Morbid/surgery ; Gastric Bypass/methods ; Retrospective Studies ; Treatment Outcome ; Bariatric Surgery/methods ; Obesity/surgery ; Weight Loss ; Gastrectomy/methods ; Diabetes Mellitus, Type 2/surgery
    Language English
    Publishing date 2023-08-11
    Publishing country United States
    Document type Multicenter Study ; Journal Article
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-023-06750-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: No association between history of psychiatric treatment and postoperative weight reduction after bariatric surgery.

    Kozela, Magdalena / Stepaniak, Urszula / Koziara, Karolina / Karpińska, Izabela / Major, Piotr / Matyja, Maciej

    Eating and weight disorders : EWD

    2024  Volume 29, Issue 1, Page(s) 19

    Abstract: Purpose: The objective of the study was to assess whether the history of psychiatric treatment was associated with (1) body weight and BMI on admission for bariatric surgery, (2) weight loss > 5 kg prior to bariatric surgery, and (3) postoperative body ... ...

    Abstract Purpose: The objective of the study was to assess whether the history of psychiatric treatment was associated with (1) body weight and BMI on admission for bariatric surgery, (2) weight loss > 5 kg prior to bariatric surgery, and (3) postoperative body weight reduction.
    Methods: Data from medical records of all consecutive patients admitted for surgical treatment of obesity in the 2nd Department of General Surgery Jagiellonian University Medical College were obtained. There were 1452 records of patients who underwent bariatric surgery between 2009 and 2021 included in the study.
    Results: History of psychiatric treatment was found in 177 (12%) of the sample and was inversely associated with body weight and BMI on admission for surgery in women. Men with history of psychiatric treatment were 54% less likely to lose > 5 kg before the surgery (OR = 0.46 95% CI = 0.24-0.88). Both in men and women %TWL did not differ significantly by history of psychiatric treatment (Me: 40.7 vs. 45.9; p = 0.130 and Me: 27.0 vs. 23.9; p = 0.383, respectively). After adjustment for covariates no association was found between history of psychiatric treatment and body weight reduction one year after surgery.
    Conclusion: Although men with preoperative history of psychiatric treatment had lower odds of losing weight before the surgery, psychiatric treatment did not differentiate the effectiveness of bariatric treatment in 1 year of observation. Bariatric surgery appears to be an effective obesity care for people treated for mental disorders.
    Level of evidence: III Evidence obtained from cohort or case-control analytic studies.
    MeSH term(s) Male ; Humans ; Female ; Obesity, Morbid/surgery ; Bariatric Surgery/psychology ; Obesity/surgery ; Weight Loss ; Case-Control Studies ; Retrospective Studies ; Treatment Outcome
    Language English
    Publishing date 2024-03-15
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2038625-4
    ISSN 1590-1262 ; 1124-4909
    ISSN (online) 1590-1262
    ISSN 1124-4909
    DOI 10.1007/s40519-024-01645-9
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  7. Article ; Online: Response to: Letter to the Editor to Impact of Intragastric Balloon Placement on the Stomach Wall: A Prospective Cohort Study.

    Rzepa, Anna / Małczak, Piotr / Karpińska, Izabela / Major, Piotr

    Obesity surgery

    2022  Volume 32, Issue 11, Page(s) 3777

    MeSH term(s) Humans ; Gastric Balloon ; Obesity, Morbid/surgery ; Prospective Studies ; Stomach/surgery ; Weight Loss
    Language English
    Publishing date 2022-09-20
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-022-06276-6
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  8. Article ; Online: Particle Size, Mass Concentration, and Microbiota in Dental Aerosols.

    Rafiee, A / Carvalho, R / Lunardon, D / Flores-Mir, C / Major, P / Quemerais, B / Altabtbaei, K

    Journal of dental research

    2022  Volume 101, Issue 7, Page(s) 785–792

    Abstract: Many dental procedures are considered aerosol-generating procedures that may put the dental operator and patients at risk for cross-infection due to contamination from nasal secretions and saliva. This aerosol, depending on the size of the particles, may ...

    Abstract Many dental procedures are considered aerosol-generating procedures that may put the dental operator and patients at risk for cross-infection due to contamination from nasal secretions and saliva. This aerosol, depending on the size of the particles, may stay suspended in the air for hours. The primary objective of the study was to characterize the size and concentrations of particles emitted from 7 different dental procedures, as well as estimate the contribution of the nasal and salivary fluids of the patient to the microbiota in the emitted bioaerosol. This cross-sectional study was conducted in an open-concept dental clinic with multiple operators at the same time. Particle size characterization and mass and particle concentrations were done by using 2 direct reading instruments: Dust-Trak DRX (Model 8534) and optical particle sizer (Model 3330). Active bioaerosol sampling was done before and during procedures. Bayesian modeling (SourceTracker2) of long-reads of the 16S ribosomal DNA was used to estimate the contribution of the patients' nasal and salivary fluids to the bioaerosol. Aerosols in most dental procedures were sub-PM
    MeSH term(s) Aerosols ; Bayes Theorem ; COVID-19 ; Cross-Sectional Studies ; Humans ; Microbiota ; Particle Size
    Chemical Substances Aerosols
    Language English
    Publishing date 2022-04-06
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80207-4
    ISSN 1544-0591 ; 0022-0345
    ISSN (online) 1544-0591
    ISSN 0022-0345
    DOI 10.1177/00220345221087880
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  9. Article ; Online: The outcomes of Re-Redo bariatric surgery-results from multicenter Polish Revision Obesity Surgery Study (PROSS).

    Łabul, Michał / Wysocki, Michał / Małczak, Piotr / Matyja, Maciej / Dowgiałło-Gornowicz, Natalia / Lech, Paweł / Szymański, Michał / Major, Piotr

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 2699

    Abstract: The increasing prevalence of bariatric surgery has resulted in a rise in the number of redo procedures as well. While redo bariatric surgery has demonstrated its effectiveness, there is still a subset of patients who may not derive any benefits from it. ... ...

    Abstract The increasing prevalence of bariatric surgery has resulted in a rise in the number of redo procedures as well. While redo bariatric surgery has demonstrated its effectiveness, there is still a subset of patients who may not derive any benefits from it. This poses a significant challenge for bariatric surgeons, especially when there is a lack of clear guidelines. The primary objective of this study is to evaluate the outcomes of patients who underwent Re-Redo bariatric surgery. We conducted a retrospective cohort study on a group of 799 patients who underwent redo bariatric surgery between 2010 and 2020. Among these patients, 20 individuals underwent a second elective redo bariatric surgery (Re-Redo) because of weight regain (15 patients) or insufficient weight loss, i.e. < 50% EWL (5 patients). Mean BMI before Re-Redo surgery was 38.8 ± 4.9 kg/m
    MeSH term(s) Humans ; Adult ; Middle Aged ; Obesity, Morbid/surgery ; Retrospective Studies ; Poland ; Obesity/surgery ; Bariatric Surgery/adverse effects ; Treatment Outcome ; Reoperation ; Gastrectomy/methods ; Laparoscopy ; Gastric Bypass/methods
    Language English
    Publishing date 2024-02-01
    Publishing country England
    Document type Multicenter Study ; Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-52817-7
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  10. Article: Current Knowledge and Perceptions of Bariatric Surgery among Diabetologists and Internists in Poland.

    Zawadzka, Karolina / Więckowski, Krzysztof / Stefura, Tomasz / Major, Piotr / Szopa, Magdalena

    Journal of clinical medicine

    2022  Volume 11, Issue 7

    Abstract: Perioperative care and follow-up after bariatric surgery (BS) engage various medical professionals. It is key for them to be well informed about these procedures. However, knowledge and attitudes may be not satisfactory enough to provide proper care. We ... ...

    Abstract Perioperative care and follow-up after bariatric surgery (BS) engage various medical professionals. It is key for them to be well informed about these procedures. However, knowledge and attitudes may be not satisfactory enough to provide proper care. We aimed to assess knowledge and perceptions of BS among diabetologists and internists. A total of 34 diabetologists and 30 internists completed the electronic questionnaire. There were no differences in self-estimated knowledge between them, except regarding items related to the treatment of diabetes and metabolic control. Several misconceptions were identified in the questions testing the understanding of key issues in BS. Most participants considered BS effective in weight loss and metabolic control. A total of 75% highlighted the lack of appropriate equipment for dealing with morbidly obese patients. Interestingly, in a multivariable linear regression model, self-estimated knowledge was the only variable associated with frequency of referrals to bariatric surgeons. A total of 92% of respondents were interested in broadening their knowledge. Guidelines for long-term follow-up and funding were the most frequently chosen topics to explore. The study showed a positive attitude of diabetologists and internists towards surgical treatment of obesity and identified some significant gaps in knowledge. The results may be helpful in planning trainings to provide the best care for patients suffering from morbid obesity.
    Language English
    Publishing date 2022-04-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm11072028
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