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  1. Article: Development of a Fast Fourier Transform-based Analytical Method for COVID-19 Diagnosis from Chest X-Ray Images Using GNU Octave.

    Majumder, Durjoy

    Journal of medical physics

    2022  Volume 47, Issue 3, Page(s) 279–286

    Abstract: Purpose: Many artificial intelligence-based computational procedures are developed to diagnose COVID-19 infection from chest X-ray (CXR) images, as diagnosis by CXR imaging is less time consuming and economically cheap compared to other detection ... ...

    Abstract Purpose: Many artificial intelligence-based computational procedures are developed to diagnose COVID-19 infection from chest X-ray (CXR) images, as diagnosis by CXR imaging is less time consuming and economically cheap compared to other detection procedures. Due to unavailability of skilled computer professionals and high computer architectural resource, majority of the employed methods are difficult to implement in rural and poor economic settings. Majority of such reports are devoid of codes and ignores related diseases (pneumonia). The absence of codes makes limitation in applying them widely. Hence, validation testing followed by evidence-based medical practice is difficult. The present work was aimed to develop a simple method that requires a less computational expertise and minimal level of computer resource, but with statistical inference.
    Materials and methods: A Fast Fourier Transform-based (FFT) method was developed with GNU Octave, a free and open-source platform. This was employed to the images of CXR for further analysis. For statistical inference, two variables, i.e., the highest peak and number of peaks in the FFT distribution plot were considered.
    Results: The comparison of mean values among different groups (normal, COVID-19, viral, and bacterial pneumonia [BP]) showed statistical significance, especially when compared to normal, except between viral and BP groups.
    Conclusion: Parametric statistical inference from our result showed high level of significance (
    Language English
    Publishing date 2022-11-08
    Publishing country India
    Document type Journal Article
    ZDB-ID 1193902-3
    ISSN 1998-3913 ; 0971-6203
    ISSN (online) 1998-3913
    ISSN 0971-6203
    DOI 10.4103/jmp.jmp_26_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A molecular docking-based comparative assessment of various anticholinergic drugs as antidotes to different nerve agent poisoning.

    Das, Bishwajit / Majumder, Durjoy

    Journal of biomolecular structure & dynamics

    2022  Volume 41, Issue 16, Page(s) 7809–7820

    Abstract: Nerve agent poisoning is still a threat to civilization. Nerve agents function by binding with the enzyme acetylcholinesterase irreversibly. Accumulation of acetylcholine in the synapse causes over-stimulation of muscarinic and nicotinic ... ...

    Abstract Nerve agent poisoning is still a threat to civilization. Nerve agents function by binding with the enzyme acetylcholinesterase irreversibly. Accumulation of acetylcholine in the synapse causes over-stimulation of muscarinic and nicotinic acetylcholinergic receptors. Thus miosis, glandular hyper secretion, bronchoconstriction, vomiting, diarrhea and bradycardia occurs (by M1-M5 receptors stimulation); whereas convulsion and seizures occur due to the nicotinic receptors. Atropine is a non-selective muscarinic antagonists but no nicotinic antagonists are known. Seizures are controlled by diazepam. Enzyme aging occurs without treatment which causes the enzyme resistant to oxime therapy. Though numerous wet-lab based works has carried out, however, recent time there is an over-growing trend to make comparative assessment of drugs and toxicants. Here we made a molecular docking based comparative assessments between nerve agents toxicity and efficacy of different drugs to prevent this toxicity. Our results suggest that VX is the most harmful organophosphate nerve agents and HI-6 is the best drug followed by Obidoxime and Pralidoxime to free acetylcholinestarase. Docking results correspond the data trend of different
    Language English
    Publishing date 2022-09-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 49157-3
    ISSN 1538-0254 ; 0739-1102
    ISSN (online) 1538-0254
    ISSN 0739-1102
    DOI 10.1080/07391102.2022.2125904
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Unusual presentation of adenoid cystic carcinoma (ACC) on lip mimicking mucocele: A rare case report with review.

    Majumder, Dipen / Rastogi, Priyanka / Kumar, Sachin / Bhardwaj, Rudra

    Journal of oral and maxillofacial pathology : JOMFP

    2023  Volume 27, Issue 3, Page(s) 605

    Abstract: Adenoid cystic carcinoma (ACC) is a relatively rare, slow-growing low-grade malignant salivary gland tumour with high recurrence. It accounts for 1% of all malignant tumour of the oral and maxillofacial region. A high incidence of cases occurs between ... ...

    Abstract Adenoid cystic carcinoma (ACC) is a relatively rare, slow-growing low-grade malignant salivary gland tumour with high recurrence. It accounts for 1% of all malignant tumour of the oral and maxillofacial region. A high incidence of cases occurs between the fifth and sixth decades of life. Surgical excision with required radiotherapy, chemotherapy, and combined therapy are possible treatment choices. In this present case, a 36-year-old male patient was diagnosed with ACC on the upper lip. The clinical presentation of this lesion resembled mucocele. There are only a few cases reported of ACC involving the lip. Complete surgical removal was done under local anaesthesia, and post-operative healing was uneventful. After 6 months of follow-up, no sign of recurrence was observed.
    Language English
    Publishing date 2023-09-12
    Publishing country India
    Document type Case Reports
    ZDB-ID 2390999-7
    ISSN 1998-393X ; 0973-029X
    ISSN (online) 1998-393X
    ISSN 0973-029X
    DOI 10.4103/jomfp.jomfp_479_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Assessing water, sanitation and hygiene (WASH) practices and their association with diarrhoea in under-five children in urban Chandernagore: Community-based evidence from a small municipal corporation in Hooghly District of West Bengal, India.

    Chatterjee, Sayantani / Majumder, Debojyoti / Roy, M N

    Journal of water and health

    2023  Volume 21, Issue 10, Page(s) 1530–1549

    Abstract: The study aims to understand the relationship of childhood diarrhoea (under-five children) with water, sanitation and hygiene factors in the light of other contextual factors in an urban setting in the district of Hooghly in West Bengal, India. This ... ...

    Abstract The study aims to understand the relationship of childhood diarrhoea (under-five children) with water, sanitation and hygiene factors in the light of other contextual factors in an urban setting in the district of Hooghly in West Bengal, India. This primary study was carried out by SIGMA Foundation, Kolkata from 4 to 24 January 2023 across 404 households having at least one under-five child. The findings suggested that the water score was 'good' in 85.1% of the households whereas the hand hygiene score was 'good' in 14.6% of households. More than 90% of the households had piped water supply. Less than half of them treated water before consumption among which 45.3% used cloths for straining water; 59.2% of the caregivers followed safe disposal of child's faeces; 66.8% of households had no handwashing arrangement, and 30.5% had taps and wash basins for handwashing; 20.3% of the under-five children had suffered from diarrhoea in the last month before the survey and its prevalence was higher in children aged 12-23 months. Multivariate results suggested diarrhoea prevalence was lower in households that were pucca and had good water and hand hygiene scores, lower in children that had received iron fortification and whose caregivers followed safe child's stool disposal.
    MeSH term(s) Humans ; Child ; Water ; Sanitation/methods ; Diarrhea/epidemiology ; Hygiene ; India/epidemiology
    Chemical Substances Water (059QF0KO0R)
    Language English
    Publishing date 2023-10-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 2123845-5
    ISSN 1996-7829 ; 1477-8920
    ISSN (online) 1996-7829
    ISSN 1477-8920
    DOI 10.2166/wh.2023.262
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Design of a polymer-based cladding mode stripper with a distributed temperature profile.

    Gomes, Vincent Akash / Chowdhury, Sajib / Maity, Shubhranil / Majumder, Debparna / Pal, Debasis / Pal, Atasi

    Applied optics

    2024  Volume 63, Issue 7, Page(s) 1769–1774

    Abstract: An optimized polymer-based fiber cladding mode stripper (CMS) is presented experimentally. A unique partial fiber stripping method is introduced in CMS fabrication to enable distributed power extraction and temperature along the length of the CMS. The ... ...

    Abstract An optimized polymer-based fiber cladding mode stripper (CMS) is presented experimentally. A unique partial fiber stripping method is introduced in CMS fabrication to enable distributed power extraction and temperature along the length of the CMS. The designed CMS based on a 400 µm double-clad fiber (DCF) extracts 300 W of inner cladding power, with an attenuation coefficient of 18.8 dB along with a temperature gradient of 0.17°C/watt. The fabricated CMS is used to develop an all-fiber 150 W thulium fiber laser at 1.94 µm.
    Language English
    Publishing date 2024-03-04
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4522
    ISSN (online) 1539-4522
    DOI 10.1364/AO.514971
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: A Menace without Specific Feature - Scrub Typhus a Reemerging Disease.

    Roychowdhury, Sujoy / Ghosh, Shibendu / Majumder, Devjit / Mukhopadhyay, Prabuddha

    The Journal of the Association of Physicians of India

    2022  Volume 69, Issue 12, Page(s) 11–12

    Abstract: Introduction: Scrub typhus is a re-emerging infectious disease. Though considered as disease of rural areas, this disease has been urbanized and the prevalence has broadened further. Disease has been reported with increasing frequency from various parts ...

    Abstract Introduction: Scrub typhus is a re-emerging infectious disease. Though considered as disease of rural areas, this disease has been urbanized and the prevalence has broadened further. Disease has been reported with increasing frequency from various parts of India and has resurgence in north east. It is a disease with multi organ involvement, with or without characteristic eschar and early detection and initial specific treatment is important.
    Material: An observational hospital-based study in patients >18years admitted to a tertiary care center in eastern India. Scrub typhus was diagnosed on basis of symptoms with or without eschar and Scrub IgM. Treated with doxycycline (azithromycin in 3 pregnant patients) & clinical course was monitored. An appropriate correlation measure, based on the natures of the variable under study, (e.g.: rank correlation / Pearson correlation/ point biserial correlation) was estimated and subsequently tested at alpha =0.05 level of significance. A p value <0.05 was taken as significant.
    Observations: A total of 105 patients of scrub typhus were included in present study. It had 66%male and 39% female with the most common age group being 46-60 years. Eschar was found in 33% patients. Neurological manifestation was found in 18% of the patients. Hyponatremia and raised liver enzymes were significantly noticed. 9% patients had Acute respiratory distress syndrome. 4% patients died because of multiorgan dysfunction. Three pregnant patients included in study were treated with azithromycin showed good response and pregnancy outcome was uneventful.
    Conclusions: Scrub typhus is no longer a disease of rural India. Physician should have strong suspicion and needs early attempt to diagnose and treat as mostly the disease is featureless and can be treated easily, but delay in starting treatment raises chances of severe complications like encephalitis, ARDS, Macrophage Activation Syndrome. Disease mostly responded with Azithromycin, Doxycycline.
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Azithromycin/therapeutic use ; Doxycycline/therapeutic use ; Female ; Humans ; Male ; Middle Aged ; Pregnancy ; Scrub Typhus/diagnosis ; Scrub Typhus/drug therapy ; Scrub Typhus/epidemiology ; Tertiary Care Centers
    Chemical Substances Anti-Bacterial Agents ; Azithromycin (83905-01-5) ; Doxycycline (N12000U13O)
    Language English
    Publishing date 2022-01-17
    Publishing country India
    Document type Journal Article ; Observational Study
    ZDB-ID 800766-4
    ISSN 0004-5772
    ISSN 0004-5772
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Mechanistic insight into the synergism of IL-27 and IL-28B in regulation of benzo(a)pyrene-induced lung carcinogenesis associated ROS/NF-κB/NLRP3 crosstalk.

    Majumder, Debabrata / Sarkar, Chaitali / Debnath, Rahul / Tribedi, Prosun / Maiti, Debasish

    Chemico-biological interactions

    2022  Volume 354, Page(s) 109807

    Abstract: Aim: Our previous work depicted that benzo(a)pyrene (BaP)-induced lung cancer associated pulmonary redox imbalance and inflammation were effectively regulated by the combinatorial treatment of IL-27 and IL-28B. So in continuation of that finding the ... ...

    Abstract Aim: Our previous work depicted that benzo(a)pyrene (BaP)-induced lung cancer associated pulmonary redox imbalance and inflammation were effectively regulated by the combinatorial treatment of IL-27 and IL-28B. So in continuation of that finding the present study was designed to reveal the inflammation regulating signaling network modulated by IL-27 and IL-28B treatment related to BaP-induced lung cancer.
    Methods: Male Swiss albino mice were treated with BaP to induce lung tumor. Then they received individual as well as combinatorial treatment of IL-27 and IL-28B. At the end of the experimental schedule, the expression of NF-κB signaling proteins, the formation of NLRP3 inflammasome complex and IL-18; IL-17A expression in the lung were observed using Western blot and RT-PCR. The tissue and serum levels of some proinflammatory cytokines were also studied using ELISA. Mast cell density was also studied using toluidine blue staining procedure.
    Results: Treatment with IL-27 or IL-28B alone was successful to regulate the expression of NF-κB signaling proteins and NLRP3 complex in some cases but best attenuation was observed in animals who received both IL-27 and IL-28B in combination. In combination, it was successful in down-regulating the expression of p-ERK1/2 and in reducing the accumulation of mast cells in the lung tissue associated with BaP-induced lung carcinogenesis. The impaired PPARγ expression was also reinstated upon combination treatment.
    Conclusion: Altogether, the treatment in combination with IL-27 and IL-28B is an effective regimen to attenuate the ROS/NF-κB/NLRP3 axis associated with BaP-induced lung carcinogenesis.
    MeSH term(s) NF-kappa B
    Chemical Substances NF-kappa B
    Language English
    Publishing date 2022-01-07
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 218799-1
    ISSN 1872-7786 ; 0009-2797
    ISSN (online) 1872-7786
    ISSN 0009-2797
    DOI 10.1016/j.cbi.2022.109807
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: A Novel Approach of Diffusion Tensor Visualization Based Neuro Fuzzy Classification System for Early Detection of Alzheimer's Disease.

    Kar, Subrata / Majumder, D Dutta

    Journal of Alzheimer's disease reports

    2019  Volume 3, Issue 1, Page(s) 1–18

    Abstract: This study examined early detection of Alzheimer's disease (AD) by diffusion tensor visualization-based methodology and neuro-fuzzy tools. Initially, we proposed a model for the early detection of AD using the measurement of apparent diffusion ... ...

    Abstract This study examined early detection of Alzheimer's disease (AD) by diffusion tensor visualization-based methodology and neuro-fuzzy tools. Initially, we proposed a model for the early detection of AD using the measurement of apparent diffusion coefficient, fractional anisotropy, and gray matter, which can determine neurological disorder patterns and abnormalities in brain white matter. These are used as input parameters into fuzzy tools, and using fuzzy rules, we evaluate the AD score as an output variable that provides a useful platform to physicians in determining the status of the disease. In the second stage, we present an investigative study on AD and used the neuro-fuzzy classification system for pattern recognition of either AD or healthy control. The experimental results are from 20 samples (14 for training, 3 for validation, and 3 for testing) used in an artificial neural network classification system. The neural network is trained with a training algorithm and the performance of the training algorithm is obtained by executing a fuzzy expert system. Out of 20 patients, 9 are AD patients and 11 are healthy control patients. We present a neuro-fuzzy tool as a better classifier for early detection of AD and obtain a satisfactory performance with 100% accuracy.
    Language English
    Publishing date 2019-01-11
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2542-4823
    ISSN (online) 2542-4823
    DOI 10.3233/ADR-180082
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Ultralight crystalline hybrid composite material for highly efficient sequestration of radioiodine.

    Fajal, Sahel / Mandal, Writakshi / Torris, Arun / Majumder, Dipanjan / Let, Sumanta / Sen, Arunabha / Kanheerampockil, Fayis / Shirolkar, Mandar M / Ghosh, Sujit K

    Nature communications

    2024  Volume 15, Issue 1, Page(s) 1278

    Abstract: Considering the importance of sustainable nuclear energy, effective management of radioactive nuclear waste, such as sequestration of radioiodine has inflicted a significant research attention in recent years. Despite the fact that materials have been ... ...

    Abstract Considering the importance of sustainable nuclear energy, effective management of radioactive nuclear waste, such as sequestration of radioiodine has inflicted a significant research attention in recent years. Despite the fact that materials have been reported for the adsorption of iodine, development of effective adsorbent with significantly improved segregation properties for widespread practical applications still remain exceedingly difficult due to lack of proper design strategies. Herein, utilizing unique hybridization synthetic strategy, a composite crystalline aerogel material has been fabricated by covalent stepping of an amino-functionalized stable cationic discrete metal-organic polyhedra with dual-pore containing imine-functionalized covalent organic framework. The ultralight hybrid composite exhibits large surface area with hierarchical macro-micro porosity and multifunctional binding sites, which collectively interact with iodine. The developed nano-adsorbent demonstrate ultrahigh vapor and aqueous-phase iodine adsorption capacities of 9.98 g.g
    Language English
    Publishing date 2024-02-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-024-45581-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Development of Low-ppm CO Sensors Using Pristine CeO

    Majumder, Deblina / Roy, Somenath

    ACS omega

    2018  Volume 3, Issue 4, Page(s) 4433–4440

    Abstract: Mesoporous ... ...

    Abstract Mesoporous CeO
    Language English
    Publishing date 2018-04-24
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.8b00146
    Database MEDical Literature Analysis and Retrieval System OnLINE

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