LIVIVO - Search results -

Search results

Result 1 - 7 of total 7

Search options

Article ; Online: Detection of Chlamydia trachomatis inside spermatozoa using flow cytometry: Effects of antibiotic treatment (before and after) on sperm count parameters.

Makarounis, Konstantinos / Leventopoulos, Michail / Georgoulias, Georgios / Nikolopoulos, Dimitris / Zeginiadou, Theodosia / Xountasi, Maria / Kotrotsos, Panagiotis / Nosi, Effrosyni / Gennimata, Vasiliki / Venieratos, Dionysios / Protogerou, Vassilis / Tsilivakos, Vassilis

Journal of microbiological methods

2022 Volume 203, Page(s) 106604

Abstract: There is increasing evidence that Chlamydia trachomatis (CT) infection can directly affect male fertility. However, only few have investigated the effects of CT on semen parameters, and mostly with inconclusive results. The main aims of this study were ... ...

Abstract	There is increasing evidence that Chlamydia trachomatis (CT) infection can directly affect male fertility. However, only few have investigated the effects of CT on semen parameters, and mostly with inconclusive results. The main aims of this study were to identify CT inside spermatozoa, and the possible pre and post antibiotic treatment effects on the overall semen parameters. We developed a flow cytometric method for the detection of CT inside spermatozoa (SPI™). Briefly, sperm cells were fixed, membrane permeabilized and DNA was loosened using DNAse. Sperm cells were incubated with a primary monoclonal antibody against CT and with a secondary fluorescent antibody (vs primary), and analysed using a flow cytometer. Of 2415 infertile individuals, 48.61% were found positive for CT. 170 CT+ samples were included in the CT antibiotic treatment study. 78.82% (134/170) of the CT+ showed a significant reduction in the percentage of the iCT infected spermatozoa after the antibiotic treatment; 59.70% (80/134) decreased to non-detectable levels. Spermcount data were also recorded. Spermatozoa morphology (normal and teratozoospermia index, TZI) and motility (fast progressive and non-progressive spermatozoa) were statistically significant altered in CT+ pre-treatment vs control group. CT antibiotic treatment showed statistically significant effects on normal spermatozoa morphology, mid-piece and tail defects, and TZI. The study demonstrated that semen flow cytometric analysis of semen could be a valuable tool for faster and accurate identification of individuals with asymptomatic CT infection. It also identified a positive effect of antibiotic therapy on semen parameters, that could help males with infertility.
MeSH term(s)	Male ; Humans ; Chlamydia trachomatis ; Semen ; Sperm Count ; Infertility, Male/drug therapy ; Infertility, Male/complications ; Flow Cytometry ; Spermatozoa ; Chlamydia Infections ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2022-10-28
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	604916-3
ISSN	1872-8359 ; 0167-7012
ISSN (online)	1872-8359
ISSN	0167-7012
DOI	10.1016/j.mimet.2022.106604
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 1849: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾

Article: Improvement of Sperm Quality in Hyperviscous Semen following DNase I Treatment.

Nosi, Effrosyni / Gritzapis, Angelos D / Makarounis, Konstantinos / Georgoulias, Georgios / Kapetanios, Vasilios / Varla-Leftherioti, Marighoula / Venieratos, Panagiotis / Papanikopoulos, Christodoulos / Konstantinidou, Anastasia / Tsilivakos, Vassilis

International journal of endocrinology

2019 Volume 2019, Page(s) 6325169

Abstract: Semen hyperviscosity impairs sperm motility and can lead to male infertility. This prospective study aimed at assessing the ability of exogenous DNase in improving sperm quality, taking into consideration that DNase has been found in the seminal plasma ... ...

Abstract	Semen hyperviscosity impairs sperm motility and can lead to male infertility. This prospective study aimed at assessing the ability of exogenous DNase in improving sperm quality, taking into consideration that DNase has been found in the seminal plasma of several species and that neutrophils release chromatin in order to trap bacteria. A total of seventy-seven semen samples with high seminal viscosity (HSV) as the study group and sixty-two semen samples with normal seminal viscosity (NSV) as the control group were compared in this analysis. These semen samples were divided into three groups of receiving treatment (a) with DNase I at 37°C for 15 min, (b) by density gradient centrifugation, and (c) with a combination of the above two methods. Following a fifteen-minute treatment of hyperviscous semen, the motility of spermatozoa in 83% of semen samples increased to a statistically significant degree. On the contrary, DNase treatment of semen with normal viscosity had no such effects. The above treatment was also accompanied by a significant increase in the percentage of normal spermatozoa, resulting in a major decrease of the teratozoospermia index. Comparison between semen samples that underwent density gradient centrifugation following DNase I treatment, to those collected after density gradient treatment alone, showed that in the first case the results were more spectacular. The evaluation of each preparation in terms of yield (% total progressively motile sperm count after treatment in relation to the initial total sperm count) revealed that the combined approach resulted in 29.8% vs. 18.5% with density treatment alone (p=0.0121). DNase I treatment results in an improvement of sperm motility and morphology and could be beneficial to men with hyperviscous semen in assisted reproduction protocols.
Language	English
Publishing date	2019-05-29
Publishing country	Egypt
Document type	Journal Article
ZDB-ID	2502951-4
ISSN	1687-8345 ; 1687-8337
ISSN (online)	1687-8345
ISSN	1687-8337
DOI	10.1155/2019/6325169
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Does Varicocele Repair Improve Conventional Semen Parameters? A Meta-Analytic Study of Before-After Data.

Cannarella, Rossella / Shah, Rupin / Hamoda, Taha Abo-Almagd Abdel-Meguid / Boitrelle, Florence / Saleh, Ramadan / Gul, Murat / Rambhatla, Amarnath / Kavoussi, Parviz / Toprak, Tuncay / Harraz, Ahmed M / Ko, Edmund / Çeker, Gökhan / Durairajanayagam, Damayanthi / Alkahidi, Noora / Kuroda, Shinnosuke / Crafa, Andrea / Henkel, Ralf / Salvio, Gianmaria / Hazir, Berk /

Darbandi, Mahsa / Bendayan, Marion / Darbandi, Sara / Falcone, Marco / Garrido, Nicolas / Kosgi, Raghavender / Sawaid Kaiyal, Raneen / Karna, Keshab / Phuoc, Nguyen Ho Vinh / Birowo, Ponco / Colpi, Giovanni M / de la Rosette, Jean / Pinggera, Germar-Michael / Nguyen, Quang / Zini, Armand / Zohdy, Wael / Singh, Rajender / Saini, Pallavi / Glina, Sidney / Lin, Haocheng / Mostafa, Taymour / Rojas-Cruz, Cesar / Arafa, Mohamed / Calogero, Aldo E / Dimitriadis, Fotios / Kothari, Priyank / Karthikeyan, Vilvapathy Senguttuvan / Okada, Keisuke / Chiba, Koji / Kadıoglu, Ates / Altay, Baris / Turunc, Tahsin / Zilaitiene, Birute / Gokalp, Fatih / Adamyan, Aram / Katz, Darren / Chung, Eric / Mierzwa, Tiago Cesar / Zylbersztejn, Daniel Suslik / Paul, Gustavo Marquesine / Sofikitis, Nikolaos / Sokolakis, Ioannis / Malhotra, Vineet / Brodjonegoro, Sakti Ronggowardhana / Adriansjah, Ricky / Tsujimura, Akira / Amano, Toshiyasu / Balercia, Giancarlo / Ziouziou, Imad / Deswanto, Isaac Ardianson / Martinez, Marlon / Park, Hyun Jun / Bakırcıoglu, Mustafa Emre / Ceyhan, Erman / Aydos, Kaan / Ramsay, Jonathan / Minhas, Suks / Al Hashimi, Manaf / Ghayda, Ramy Abou / Tadros, Nicholas / Sindhwani, Puneet / Ho, Christopher C K / Rachman, Rinaldo Indra / Rodriguez Pena, Marcelo / Motawi, Ahmad / Ponnusamy, Arun Karthik / Dipankar, Satish / Amir, Azwar / Binsaleh, Saleh / Serefoglu, Ege Can / Banthia, Ravi / Khalafalla, Kareim / Basukarno, Ari / Bac, Nguyen Hoai / Singla, Karun / Ambar, Rafael F / Makarounis, Konstantinos / Priyadarshi, Shivam / Duarsa, Gede Wirya Kusuma / Atmoko, Widi / Jindal, Sunil / Arianto, Eko / Akhavizadegan, Hamed / El Bardisi, Haitham / Shoshany, Ohad / Busetto, Gian Maria / Moussa, Mohamad / Jamali, Mounir / Al-Marhoon, Mohamed S / Ruzaev, Mikhail / Farsi, Hasan M A / Mutambirwa, Shingai / Lee, Dong Sup / Kulaksiz, Deniz / Cheng, Yu-Sheng / Bouzouita, Abderrazak / Sarikaya, Selcuk / Kandil, Hussein / Tsampoukas, Georgios / Farkouh, Ala'a / Bowa, Kasonde / Savira, Missy / Mogharabian, Nasser / Le, Tan V / Harjanggi, Maruto / Anh, Dang Tuan / Long, Tran Quang Tien / Soebadi, Mohammad Ayodhia / Hakim, Lukman / Tanic, Marko / Ari, Umut Cagin / Parikh, Firuza R / Calik, Gokhan / Kv, Vinod / Dorji, Gyem / Rezano, Andri / Rajmil, Osvaldo / Tien, Dung Mai Ba / Yuan, Yiming / Lizarraga-Salas, Juan Francisco / Eze, Balantine / Ngoo, Kay Seong / Lee, Joe / Arslan, Umut / Agarwal, Ashok

The world journal of men's health

2023 Volume 42, Issue 1, Page(s) 92–132

Abstract: Purpose: The purpose of this meta-analysis is to study the impact of varicocele repair in the largest cohort of infertile males with clinical varicocele by including all available studies, with no language restrictions, comparing intra-person ... ...

Abstract	Purpose: The purpose of this meta-analysis is to study the impact of varicocele repair in the largest cohort of infertile males with clinical varicocele by including all available studies, with no language restrictions, comparing intra-person conventional semen parameters before and after the repair of varicoceles. Materials and methods: The meta-analysis was performed according to PRISMA-P and MOOSE guidelines. A systematic search was performed in Scopus, PubMed, Cochrane, and Embase databases. Eligible studies were selected according to the PICOS model (Population: infertile male patients with clinical varicocele; Intervention: varicocele repair; Comparison: intra-person before-after varicocele repair; Outcome: conventional semen parameters; Study type: randomized controlled trials [RCTs], observational and case-control studies). Results: Out of 1,632 screened abstracts, 351 articles (23 RCTs, 292 observational, and 36 case-control studies) were included in the quantitative analysis. The before-and-after analysis showed significant improvements in all semen parameters after varicocele repair (except sperm vitality); semen volume: standardized mean difference (SMD) 0.203, 95% CI: 0.129-0.278; p<0.001; I²=83.62%, Egger's p=0.3329; sperm concentration: SMD 1.590, 95% CI: 1.474-1.706; p<0.001; I²=97.86%, Egger's p<0.0001; total sperm count: SMD 1.824, 95% CI: 1.526-2.121; p<0.001; I²=97.88%, Egger's p=0.0063; total motile sperm count: SMD 1.643, 95% CI: 1.318-1.968; p<0.001; I²=98.65%, Egger's p=0.0003; progressive sperm motility: SMD 1.845, 95% CI: 1.537%-2.153%; p<0.001; I²=98.97%, Egger's p<0.0001; total sperm motility: SMD 1.613, 95% CI 1.467%-1.759%; p<0.001; l2=97.98%, Egger's p<0.001; sperm morphology: SMD 1.066, 95% CI 0.992%-1.211%; p<0.001; I²=97.87%, Egger's p=0.1864. Conclusions: The current meta-analysis is the largest to date using paired analysis on varicocele patients. In the current meta-analysis, almost all conventional semen parameters improved significantly following varicocele repair in infertile patients with clinical varicocele.
Language	English
Publishing date	2023-06-22
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2719786-4
ISSN	2287-4690 ; 2287-4208
ISSN (online)	2287-4690
ISSN	2287-4208
DOI	10.5534/wjmh.230034
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Global Practice Patterns and Variations in the Medical and Surgical Management of Non-Obstructive Azoospermia: Results of a World-Wide Survey, Guidelines and Expert Recommendations.

Rambhatla, Amarnath / Shah, Rupin / Ziouziou, Imad / Kothari, Priyank / Salvio, Gianmaria / Gul, Murat / Hamoda, Taha / Kavoussi, Parviz / Atmoko, Widi / Toprak, Tuncay / Birowo, Ponco / Ko, Edmund / Arafa, Mohamed / Ghayda, Ramy Abou / Karthikeyan, Vilvapathy Senguttuvan / Russo, Giorgio Ivan / Pinggera, Germar-Michael / Chung, Eric / Harraz, Ahmed M /

Martinez, Marlon / Phuoc, Nguyen Ho Vinh / Tadros, Nicholas / Saleh, Ramadan / Savira, Missy / Colpi, Giovanni M / Zohdy, Wael / Pescatori, Edoardo / Park, Hyun Jun / Fukuhara, Shinichiro / Tsujimura, Akira / Rojas-Cruz, Cesar / Marino, Angelo / Mak, Siu King / Amar, Edouard / Ibrahim, Wael / Sindhwani, Puneet / Alhathal, Naif / Busetto, Gian Maria / Al Hashimi, Manaf / El-Sakka, Ahmed / Ramazan, Asci / Dimitriadis, Fotios / Timpano, Massimiliano / Jezek, Davor / Altay, Baris / Zylbersztejn, Daniel Suslik / Wong, Michael Yc / Moon, Du Geon / Wyns, Christine / Gamidov, Safar / Akhavizadegan, Hamed / Franceschelli, Alessandro / Aydos, Kaan / Quang, Nguyen / Ashour, Shedeed / Al Dayel, Adel / Al-Marhoon, Mohammed S / Micic, Sava / Binsaleh, Saleh / Hussein, Alayman / Elbardisi, Haitham / Mostafa, Taymour / Ramsay, Jonathan / Zachariou, Athanasios / Abdelrahman, Islam Fathy Soliman / Rajmil, Osvaldo / Kalkanli, Arif / Molina, Juan Manuel Corral / Bocu, Kadir / Duarsa, Gede Wirya Kusuma / Çeker, Gökhan / Serefoglu, Ege Can / Bahar, Fahmi / Gherabi, Nazim / Kuroda, Shinnosuke / Bouzouita, Abderrazak / Gudeloglu, Ahmet / Ceyhan, Erman / Hasan, Mohamed Saeed Mohamed / Musa, Muhammad Ujudud / Motawi, Ahmad / Cho, Chak-Lam / Taniguchi, Hisanori / Ho, Christopher Chee Kong / Vazquez, Jesus Fernando Solorzano / Mutambirwa, Shingai / Gungor, Nur Dokuzeylul / Bendayan, Marion / Giulioni, Carlo / Baser, Aykut / Falcone, Marco / Boeri, Luca / Blecher, Gideon / Kheradmand, Alireza / Sethupathy, Tamilselvi / Adriansjah, Ricky / Narimani, Nima / Konstantinidis, Charalampos / Nguyen, Tuan Thanh / Japari, Andrian / Dolati, Parisa / Singh, Keerti / Ozer, Cevahir / Sarikaya, Selcuk / Sheibak, Nadia / Bosco, Ndagijimana Jean / Özkent, Mehmet Serkan / Le, Sang Thanh / Sokolakis, Ioannis / Katz, Darren / Smith, Ryan / Truong, Manh Nguyen / Le, Tan V / Huang, Zhongwei / Deger, Muslim Dogan / Arslan, Umut / Calik, Gokhan / Franco, Giorgio / Rashed, Ayman / Kahraman, Oguzhan / Andreadakis, Sotiris / Putra, Rosadi / Balercia, Giancarlo / Khalafalla, Kareim / Cannarella, Rossella / Tuân, Anh Ðăng / El Meliegy, Amr / Zilaitiene, Birute / Ramirez, Marlene Lizbeth Zamora / Giacone, Filippo / Calogero, Aldo E / Makarounis, Konstantinos / Jindal, Sunil / Hoai, Bac Nguyen / Banthia, Ravi / Peña, Marcelo Rodriguez / Moorthy, Dharani / Adamyan, Aram / Kulaksiz, Deniz / Kandil, Hussein / Sofikitis, Nikolaos / Salzano, Ciro / Jungwirth, Andreas / Banka, Surendra Reddy / Mierzwa, Tiago Cesar / Turunç, Tahsin / Jain, Divyanu / Avoyan, Armen / Salacone, Pietro / Kadıoğlu, Ateş / Gupta, Chirag / Lin, Haocheng / Shamohammadi, Iman / Mogharabian, Nasser / Barrett, Trenton / Danacıoğlu, Yavuz Onur / Crafa, Andrea / Daoud, Salima / Malhotra, Vineet / Almardawi, Abdulmalik / Selim, Osama Mohamed / Moussa, Mohamad / Haghdani, Saeid / Duran, Mesut Berkan / Kunz, Yannic / Preto, Mirko / Eugeni, Elena / Nguyen, Thang / Elshahid, Ahmed Rashad / Suyono, Seso Sulijaya / Parikesit, Dyandra / Nada, Essam / Orozco, Eduardo Gutiérrez / Boitrelle, Florence / Trang, Nguyen Thi Minh / Jamali, Mounir / Nair, Raju / Ruzaev, Mikhail / Gadda, Franco / Thomas, Charalampos / Ferreira, Raphael Henrique / Gul, Umit / Maruccia, Serena / Kanbur, Ajay / Kinzikeeva, Ella / Abumelha, Saad Mohammed / Kosgi, Raghavender / Gokalp, Fatih / Soebadi, Mohammad Ayodhia / Paul, Gustavo Marquesine / Sajadi, Hesamoddin / Gupte, Deepak / Ambar, Rafael F / Sogutdelen, Emrullah / Singla, Karun / Basukarno, Ari / Kim, Shannon Hee Kyung / Gilani, Mohammad Ali Sadighi / Nagao, Koichi / Brodjonegoro, Sakti Ronggowardhana / Rezano, Andri / Elkhouly, Mohamed / Mazzilli, Rossella / Farsi, Hasan M A / Ba, Hung Nguyen / Alali, Hamed / Kafetzis, Dimitrios / Long, Tran Quang Tien / Alsaid, Sami / Cuong, Hoang Bao Ngoc / Oleksandr, Knigavko / Mustafa, Akhmad / Acosta, Herik / Pai, Hrishikesh / Şahin, Bahadır / Arianto, Eko / Teo, Colin / Jayaprakash, Sanjay Prakash / Rachman, Rinaldo Indra / Yenice, Mustafa Gurkan / Sefrioui, Omar / Priyadarshi, Shivam / Tanic, Marko / Alfatlaw, Noor Kareem / Rizaldi, Fikri / Vishwakarma, Ranjit B / Kanakis, George / Cherian, Dinesh Thomas / Lee, Joe / Galstyan, Raisa / Keskin, Hakan / Wurzacher, Janan / Seno, Doddy Hami / Noegroho, Bambang S / Margiana, Ria / Javed, Qaisar / Castiglioni, Fabrizio / Tanwar, Raman / Puigvert, Ana / Kaya, Coşkun / Purnomo, Medianto / Yazbeck, Chadi / Amir, Azwar / Borges, Edson / Bellavia, Marina / Deswanto, Isaac Ardianson / Kv, Vinod / Liguori, Giovanni / Minh, Dang Hoang / Siddiqi, Kashif / Colombo, Fulvio / Zini, Armand / Patel, Niket / Çayan, Selahittin / Al-Kawaz, Ula / Ragab, Maged / Hebrard, Guadalupe Hernández / de la Rosette, Jean / Efesoy, Ozan / Hoffmann, Ivan / Teixeira, Thiago Afonso / Saylam, Barış / Delgadillo, Daniela / Agarwal, Ashok

The world journal of men's health

2024

Abstract: Purpose: Non-obstructive azoospermia (NOA) is a common, but complex problem, with multiple therapeutic options and a lack of clear guidelines. Hence, there is considerable controversy and marked variation in the management of NOA. This survey evaluates ... ...

Abstract	Purpose: Non-obstructive azoospermia (NOA) is a common, but complex problem, with multiple therapeutic options and a lack of clear guidelines. Hence, there is considerable controversy and marked variation in the management of NOA. This survey evaluates contemporary global practices related to medical and surgical management for patients with NOA. Materials and methods: A 56-question online survey covering various aspects of the evaluation and management of NOA was sent to specialists around the globe. This paper analyzes the results of the second half of the survey dealing with the management of NOA. Results have been compared to current guidelines, and expert recommendations have been provided using a Delphi process. Results: Participants from 49 countries submitted 336 valid responses. Hormonal therapy for 3 to 6 months was suggested before surgical sperm retrieval (SSR) by 29.6% and 23.6% of participants for normogonadotropic hypogonadism and hypergonadotropic hypogonadism respectively. The SSR rate was reported as 50.0% by 26.0% to 50.0% of participants. Interestingly, 46.0% reported successful SSR in <10% of men with Klinefelter syndrome and 41.3% routinely recommended preimplantation genetic testing. Varicocele repair prior to SSR is recommended by 57.7%. Half of the respondents (57.4%) reported using ultrasound to identify the most vascularized areas in the testis for SSR. One-third proceed directly to microdissection testicular sperm extraction (mTESE) in every case of NOA while others use a staged approach. After a failed conventional TESE, 23.8% wait for 3 months, while 33.1% wait for 6 months before proceeding to mTESE. The cut-off of follicle-stimulating hormone for positive SSR was reported to be 12-19 IU/mL by 22.5% of participants and 20-40 IU/mL by 27.8%, while 31.8% reported no upper limit. Conclusions: This is the largest survey to date on the real-world medical and surgical management of NOA by reproductive experts. It demonstrates a diverse practice pattern and highlights the need for evidence-based international consensus guidelines.
Language	English
Publishing date	2024-04-04
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2719786-4
ISSN	2287-4690 ; 2287-4208
ISSN (online)	2287-4690
ISSN	2287-4208
DOI	10.5534/wjmh.230339
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Global Practice Patterns in the Evaluation of Non-Obstructive Azoospermia: Results of a World-Wide Survey and Expert Recommendations.

Shah, Rupin / Rambhatla, Amarnath / Atmoko, Widi / Martinez, Marlon / Ziouziou, Imad / Kothari, Priyank / Tadros, Nicholas / Phuoc, Nguyen Ho Vinh / Kavoussi, Parviz / Harraz, Ahmed / Salvio, Gianmaria / Gul, Murat / Hamoda, Taha / Toprak, Tuncay / Birowo, Ponco / Ko, Edmund / Arafa, Mohamed / Ghayda, Ramy Abou / Karthikeyan, Vilvapathy Senguttuvan /

Saleh, Ramadan / Russo, Giorgio Ivan / Pinggera, Germar-Michael / Chung, Eric / Savira, Missy / Colpi, Giovanni M / Zohdy, Wael / Pescatori, Edoardo / Park, Hyun Jun / Fukuhara, Shinichiro / Tsujimura, Akira / Rojas-Cruz, Cesar / Marino, Angelo / Mak, Siu King / Amar, Edouard / Ibrahim, Wael / Sindhwani, Puneet / Alhathal, Naif / Busetto, Gian Maria / Al Hashimi, Manaf / El-Sakka, Ahmed / Ramazan, Asci / Dimitriadis, Fotios / Timpano, Massimiliano / Jezek, Davor / Altay, Baris / Zylbersztejn, Daniel Suslik / Wong, Michael Yc / Moon, Du Geon / Wyns, Christine / Gamidov, Safar / Akhavizadegan, Hamed / Franceschelli, Alessandro / Aydos, Kaan / Quang, Vinh Nguyen / Ashour, Shedeed / Al Dayel, Adel / Al-Marhoon, Mohamed S / Micic, Sava / Binsaleh, Saleh / Hussein, Alayman / Elbardisi, Haitham / Mostafa, Taymour / Taha, Emad / Ramsay, Jonathan / Zachariou, Athanasios / Abdelrahman, Islam Fathy Soliman / Rajmil, Osvaldo / Kalkanli, Arif / Molina, Juan Manuel Corral / Bocu, Kadir / Duarsa, Gede Wirya Kusuma / Ceker, Gokhan / Serefoglu, Ege Can / Bahar, Fahmi / Gherabi, Nazim / Kuroda, Shinnosuke / Bouzouita, Abderrazak / Gudeloglu, Ahmet / Ceyhan, Erman / Hasan, Mohamed Saeed Mohamed / Musa, Muhammad Ujudud / Motawi, Ahmad / Chak-Lam, Cho / Taniguchi, Hisanori / Ho, Christopher Chee Kong / Vazquez, Jesus Fernando Solorzano / Mutambirwa, Shingai / Gungor, Nur Dokuzeylul / Bendayan, Marion / Giulioni, Carlo / Baser, Aykut / Falcone, Marco / Boeri, Luca / Blecher, Gideon / Kheradmand, Alireza / Sethupathy, Tamilselvi / Adriansjah, Ricky / Narimani, Nima / Konstantinidis, Charalampos / Nguyen, Tuan Thanh / Japari, Andrian / Dolati, Parisa / Singh, Keerti / Ozer, Cevahir / Sarikaya, Selcuk / Sheibak, Nadia / Bosco, Ndagijimana Jean / Özkent, Mehmet Serkan / Le, Sang Thanh / Sokolakis, Ioannis / Katz, Darren / Smith, Ryan / Truong, Manh Nguyen / Le, Tan V / Huang, Zhongwei / Deger, Muslim Dogan / Arslan, Umut / Calik, Gokhan / Franco, Giorgio / Rashed, Ayman / Kahraman, Oguzhan / Andreadakis, Sotiris / Putra, Rosadi / Balercia, Giancarlo / Khalafalla, Kareim / Cannarella, Rossella / Tuân, Anh Ðăng / El Meliegy, Amr / Zilaitiene, Birute / Ramirez, Marlene Lizbeth Zamora / Giacone, Filippo / Calogero, Aldo E / Makarounis, Konstantinos / Jindal, Sunil / Hoai, Bac Nguyen / Banthia, Ravi / Peña, Marcelo Rodriguez / Moorthy, Dharani / Adamyan, Aram / Kulaksiz, Deniz / Kandil, Hussein / Sofikitis, Nikolaos / Salzano, Ciro / Jungwirth, Andreas / Banka, Surendra Reddy / Mierzwa, Tiago Cesar / Turunç, Tahsin / Jain, Divyanu / Avoyan, Armen / Salacone, Pietro / Kadıoğlu, Ateş / Gupta, Chirag / Lin, Haocheng / Shamohammadi, Iman / Mogharabian, Nasser / Barrett, Trenton / Danacıoğlu, Yavuz Onur / Crafa, Andrea / Daoud, Salima / Malhotra, Vineet / Almardawi, Abdulmalik / Selim, Osama Mohamed / Moussa, Mohamad / Haghdani, Saeid / Duran, Mesut Berkan / Kunz, Yannic / Preto, Mirko / Eugeni, Elena / Nguyen, Thang / Elshahid, Ahmed Rashad / Suyono, Seso Sulijaya / Parikesit, Dyandra / Nada, Essam / Orozco, Eduardo Gutiérrez / Boitrelle, Florence / Trang, Nguyen Thi Minh / Jamali, Mounir / Nair, Raju / Ruzaev, Mikhail / Gadda, Franco / Thomas, Charalampos / Ferreira, Raphael Henrique / Gul, Umit / Maruccia, Serena / Kanbur, Ajay / Kinzikeeva, Ella / Abumelha, Saad / Quang, Nguyen / Kosgi, Raghavender / Gokalp, Fatih / Soebadi, Mohammad Ayodhia / Paul, Gustavo Marquesine / Sajadi, Hesamoddin / Gupte, Deepak / Ambar, Rafael F / Sogutdelen, Emrullah / Singla, Karun / Basurkano, Ari / Kim, Shannon Hee Kyung / Gilani, Mohammad Ali Sadighi / Nagao, Koichi / Brodjonegoro, Sakti Ronggowardhana / Rezano, Andri / Elkhouly, Mohamed / Mazzilli, Rossella / Farsi, Hasan M A / Ba, Hung Nguyen / Alali, Hamed / Kafetzis, Dimitrios / Long, Tran Quang Tien / Alsaid, Sami / Cuong, Hoang Bao Ngoc / Oleksandr, Knigavko / Mustafa, Akhmad / Acosta, Herik / Pai, Hrishikesh / Şahin, Bahadır / Arianto, Eko / Teo, Colin / Jayaprakash, Sanjay Prakash / Rachman, Rinaldo Indra / Yenice, Mustafa Gurkan / Sefrioui, Omar / Paghdar, Smit / Priyadarshi, Shivam / Tanic, Marko / Alfatlawy, Noor Kareem / Rizaldi, Fikri / Vishwakarma, Ranjit B / Kanakis, George / Cherian, Dinesh Thomas / Lee, Joe / Galstyan, Raisa / Keskin, Hakan / Wurzacher, Jana / Seno, Doddy Hami / Noegroho, Bambang S / Margiana, Ria / Javed, Qaisar / Castiglioni, Fabrizio / Tanwar, Raman / Puigvert, Ana / Kaya, Coşkun / Purnomo, Medianto / Yazbeck, Chadi / Amir, Azwar / Borges, Edson / Bellavia, Marina / Deswanto, Isaac Ardianson / V, Vinod K / Liguori, Giovanni / Minh, Dang Hoang / Siddiqi, Kashif / Colombo, Fulvio / Zini, Armand / Patel, Niket / Çayan, Selahittin / Al-Kawaz, Ula / Ragab, Maged / Hebrard, Guadalupe Hernández / Hoffmann, Ivan / Efesoy, Ozan / Saylam, Barış / Agarwal, Ashok

The world journal of men's health

2024

Abstract: Purpose: Non-obstructive azoospermia (NOA) represents the persistent absence of sperm in ejaculate without obstruction, stemming from diverse disease processes. This survey explores global practices in NOA diagnosis, comparing them with guidelines and ... ...

Abstract	Purpose: Non-obstructive azoospermia (NOA) represents the persistent absence of sperm in ejaculate without obstruction, stemming from diverse disease processes. This survey explores global practices in NOA diagnosis, comparing them with guidelines and offering expert recommendations. Materials and methods: A 56-item questionnaire survey on NOA diagnosis and management was conducted globally from July to September 2022. This paper focuses on part 1, evaluating NOA diagnosis. Data from 367 participants across 49 countries were analyzed descriptively, with a Delphi process used for expert recommendations. Results: Of 336 eligible responses, most participants were experienced attending physicians (70.93%). To diagnose azoospermia definitively, 81.7% requested two semen samples. Commonly ordered hormone tests included serum follicle-stimulating hormone (FSH) (97.0%), total testosterone (92.9%), and luteinizing hormone (86.9%). Genetic testing was requested by 66.6%, with karyotype analysis (86.2%) and Y chromosome microdeletions (88.3%) prevalent. Diagnostic testicular biopsy, distinguishing obstructive azoospermia (OA) from NOA, was not performed by 45.1%, while 34.6% did it selectively. Differentiation relied on physical examination (76.1%), serum hormone profiles (69.6%), and semen tests (68.1%). Expectations of finding sperm surgically were higher in men with normal FSH, larger testes, and a history of sperm in ejaculate. Conclusions: This expert survey, encompassing 367 participants from 49 countries, unveils congruence with recommended guidelines in NOA diagnosis. However, noteworthy disparities in practices suggest a need for evidence-based, international consensus guidelines to standardize NOA evaluation, addressing existing gaps in professional recommendations.
Language	English
Publishing date	2024-04-03
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2719786-4
ISSN	2287-4690 ; 2287-4208
ISSN (online)	2287-4690
ISSN	2287-4208
DOI	10.5534/wjmh.230333
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Controversy and Consensus on the Management of Elevated Sperm DNA Fragmentation in Male Infertility: A Global Survey, Current Guidelines, and Expert Recommendations.

Farkouh, Ala'a / Agarwal, Ashok / Hamoda, Taha Abo-Almagd Abdel-Meguid / Kavoussi, Parviz / Saleh, Ramadan / Zini, Armand / Arafa, Mohamed / Harraz, Ahmed M / Gul, Murat / Karthikeyan, Vilvapathy Senguttuvan / Durairajanayagam, Damayanthi / Rambhatla, Amarnath / Boitrelle, Florence / Chung, Eric / Birowo, Ponco / Toprak, Tuncay / Ghayda, Ramy Abou / Cannarella, Rossella / Phuoc, Nguyen Ho Vinh /

Dimitriadis, Fotios / Russo, Giorgio I / Sokolakis, Ioannis / Mostafa, Taymour / Makarounis, Konstantinos / Ziouziou, Imad / Kuroda, Shinnosuke / Bendayan, Marion / Kaiyal, Raneen Sawaid / Japari, Andrian / Simopoulou, Mara / Rocco, Lucia / Garrido, Nicolas / Gherabi, Nazim / Bocu, Kadir / Kahraman, Oguzhan / Le, Tan V / Wyns, Christine / Tremellen, Kelton / Sarikaya, Selcuk / Lewis, Sheena / Evenson, Donald P / Ko, Edmund / Calogero, Aldo E / Bahar, Fahmi / Martinez, Marlon / Crafa, Andrea / Nguyen, Quang / Ambar, Rafael F / Colpi, Giovanni / Bakircioglu, Mustafa Emre / Henkel, Ralf / Kandil, Hussein / Serefoglu, Ege Can / Alarbid, Abdullah / Tsujimura, Akira / Kheradmand, Alireza / Anagnostopoulou, Christina / Marino, Angelo / Adamyan, Aram / Zilaitiene, Birute / Ozer, Cevahir / Pescatori, Edoardo / Vogiatzi, Paraskevi / Busetto, Gian Maria / Balercia, Giancarlo / Elbardisi, Haitham / Akhavizadegan, Hamed / Sajadi, Hesamoddin / Taniguchi, Hisanori / Park, Hyun Jun / Maldonado Rosas, Israel / Al-Marhoon, Mohamed / Sadighi Gilani, Mohammad Ali / Alhathal, Naif / Pinggera, Germar-Michael / Kothari, Priyank / Mogharabian, Nasser / Micic, Sava / Homa, Sheryl / Darbandi, Sara / Long, Tran Quang Tien / Zohdy, Wael / Atmoko, Widi / Sabbaghian, Marjan / Ibrahim, Wael / Smith, Ryan P / Ho, Christopher Chee Kong / de la Rosette, Jean / El-Sakka, Ahmed I / Preto, Mirko / Zenoaga-Barbăroșie, Cătălina / Abumelha, Saad Mohammed / Baser, Aykut / Aydos, Kaan / Ramirez-Dominguez, Liliana / Kumar, Vijay / Ong, Teng Aik / Mierzwa, Tiago Cesar / Adriansjah, Ricky / Banihani, Saleem A / Bowa, Kasonde / Fukuhara, Shinichiro / Rodriguez Peña, Marcelo / Moussa, Mohamad / Ari, Umut Çağın / Cho, Chak-Lam / Tadros, Nicholas N / Ugur, Muhammet Rasit / Amar, Edouard / Falcone, Marco / Santer, Frederic Romain / Kalkanli, Arif / Karna, Keshab Kumar / Khalafalla, Kareim / Vishwakarma, Ranjit B / Finocchi, Federica / Giulioni, Carlo / Ceyhan, Erman / Çeker, Gökhan / Yazbeck, Chadi / Rajmil, Osvaldo / Yilmaz, Mehmet / Altay, Baris / Barrett, Trenton L / Ngoo, Kay Seong / Roychoudhury, Shubhadeep / Salvio, Gianmaria / Lin, Haocheng / Kadioglu, Ates / Timpano, Massimiliano / Avidor-Reiss, Tomer / Hakim, Lukman / Sindhwani, Puneet / Franco, Giorgio / Singh, Rajender / Giacone, Filippo / Ruzaev, Mikhail / Kosgi, Raghavender / Sofikitis, Nikolaos / Palani, Ayad / Calik, Gokhan / Kulaksız, Deniz / Jezek, Davor / Al Hashmi, Manaf / Drakopoulos, Panagiotis / Omran, Huda / Leonardi, Sofia / Celik-Ozenci, Ciler / Güngör, Nur Dokuzeylül / Ramsay, Jonathan / Amano, Toshiyasu / Sogutdelen, Emrullah / Duarsa, Gede Wirya Kusuma / Chiba, Koji / Jindal, Sunil / Savira, Missy / Boeri, Luca / Borges, Edson / Gupte, Deepak / Gokalp, Fatih / Hebrard, Guadalupe Hernández / Minhas, Suks / Shah, Rupin

The world journal of men's health

2023 Volume 41, Issue 4, Page(s) 809–847

Abstract: Purpose: Sperm DNA fragmentation (SDF) has been associated with male infertility and poor outcomes of assisted reproductive technology (ART). The purpose of this study was to investigate global practices related to the management of elevated SDF in ... ...

Abstract	Purpose: Sperm DNA fragmentation (SDF) has been associated with male infertility and poor outcomes of assisted reproductive technology (ART). The purpose of this study was to investigate global practices related to the management of elevated SDF in infertile men, summarize the relevant professional society recommendations, and provide expert recommendations for managing this condition. Materials and methods: An online global survey on clinical practices related to SDF was disseminated to reproductive clinicians, according to the CHERRIES checklist criteria. Management protocols for various conditions associated with SDF were captured and compared to the relevant recommendations in professional society guidelines and the appropriate available evidence. Expert recommendations and consensus on the management of infertile men with elevated SDF were then formulated and adapted using the Delphi method. Results: A total of 436 experts from 55 different countries submitted responses. As an initial approach, 79.1% of reproductive experts recommend lifestyle modifications for infertile men with elevated SDF, and 76.9% prescribe empiric antioxidants. Regarding antioxidant duration, 39.3% recommend 4-6 months and 38.1% recommend 3 months. For men with unexplained or idiopathic infertility, and couples experiencing recurrent miscarriages associated with elevated SDF, most respondents refer to ART 6 months after failure of conservative and empiric medical management. Infertile men with clinical varicocele, normal conventional semen parameters, and elevated SDF are offered varicocele repair immediately after diagnosis by 31.4%, and after failure of antioxidants and conservative measures by 40.9%. Sperm selection techniques and testicular sperm extraction are also management options for couples undergoing ART. For most questions, heterogenous practices were demonstrated. Conclusions: This paper presents the results of a large global survey on the management of infertile men with elevated SDF and reveals a lack of consensus among clinicians. Furthermore, it demonstrates the scarcity of professional society guidelines in this regard and attempts to highlight the relevant evidence. Expert recommendations are proposed to help guide clinicians.
Language	English
Publishing date	2023-04-20
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2719786-4
ISSN	2287-4690 ; 2287-4208
ISSN (online)	2287-4690
ISSN	2287-4208
DOI	10.5534/wjmh.230008
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Consensus and Diversity in the Management of Varicocele for Male Infertility: Results of a Global Practice Survey and Comparison with Guidelines and Recommendations.

Shah, Rupin / Agarwal, Ashok / Kavoussi, Parviz / Rambhatla, Amarnath / Saleh, Ramadan / Cannarella, Rossella / Harraz, Ahmed M / Boitrelle, Florence / Kuroda, Shinnosuke / Hamoda, Taha Abo-Almagd Abdel-Meguid / Zini, Armand / Ko, Edmund / Calik, Gokhan / Toprak, Tuncay / Kandil, Hussein / Gül, Murat / Bakırcıoğlu, Mustafa Emre / Parekh, Neel / Russo, Giorgio Ivan /

Tadros, Nicholas / Kadioglu, Ates / Arafa, Mohamed / Chung, Eric / Rajmil, Osvaldo / Dimitriadis, Fotios / Malhotra, Vineet / Salvio, Gianmaria / Henkel, Ralf / Le, Tan V / Sogutdelen, Emrullah / Vij, Sarah / Alarbid, Abdullah / Gudeloglu, Ahmet / Tsujimura, Akira / Calogero, Aldo E / El Meliegy, Amr / Crafa, Andrea / Kalkanli, Arif / Baser, Aykut / Hazir, Berk / Giulioni, Carlo / Cho, Chak-Lam / Ho, Christopher C K / Salzano, Ciro / Zylbersztejn, Daniel Suslik / Tien, Dung Mai Ba / Pescatori, Edoardo / Borges, Edson / Serefoglu, Ege Can / Saïs-Hamza, Emine / Huyghe, Eric / Ceyhan, Erman / Caroppo, Ettore / Castiglioni, Fabrizio / Bahar, Fahmi / Gokalp, Fatih / Lombardo, Francesco / Gadda, Franco / Duarsa, Gede Wirya Kusuma / Pinggera, Germar-Michael / Busetto, Gian Maria / Balercia, Giancarlo / Cito, Gianmartin / Blecher, Gideon / Franco, Giorgio / Liguori, Giovanni / Elbardisi, Haitham / Keskin, Hakan / Lin, Haocheng / Taniguchi, Hisanori / Park, Hyun Jun / Ziouziou, Imad / de la Rosette, Jean / Hotaling, Jim / Ramsay, Jonathan / Molina, Juan Manuel Corral / Lo, Ka Lun / Bocu, Kadir / Khalafalla, Kareim / Bowa, Kasonde / Okada, Keisuke / Nagao, Koichi / Chiba, Koji / Hakim, Lukman / Makarounis, Konstantinos / Hehemann, Marah / Rodriguez Peña, Marcelo / Falcone, Marco / Bendayan, Marion / Martinez, Marlon / Timpano, Massimiliano / Altan, Mesut / Fode, Mikkel / Al-Marhoon, Mohamed S / Sadighi Gilani, Mohammad Ali / Soebadi, Mohammad Ayodhia / Gherabi, Nazim / Sofikitis, Nikolaos / Kahraman, Oğuzhan / Birowo, Ponco / Kothari, Priyank / Sindhwani, Puneet / Javed, Qaisar / Ambar, Rafael F / Kosgi, Raghavender / Ghayda, Ramy Abou / Adriansjah, Ricky / Condorelli, Rosita Angela / La Vignera, Sandro / Micic, Sava / Kim, Shannon Hee Kyung / Fukuhara, Shinichiro / Ahn, Sun Tae / Mostafa, Taymour / Ong, Teng Aik / Takeshima, Teppei / Amano, Toshiyasu / Barrett, Trenton / Arslan, Umut / Karthikeyan, Vilvapathy Senguttuvan / Atmoko, Widi / Yumura, Yasushi / Yuan, Yiming / Kato, Yuki / Jezek, Davor / Cheng, Bryan Kwun-Chung / Hatzichristodoulou, Georgios / Dy, Jun / Castañé, Eduard Ruiz / El-Sakka, Ahmed I / Nguyen, Quang / Sarikaya, Selcuk / Boeri, Luca / Tan, Ronny / Moussa, Mohamad A / El-Assmy, Ahmed / Alali, Hamed / Alhathal, Naif / Osman, Yasser / Perovic, Dragoljub / Sajadi, Hesamoddin / Akhavizadegan, Hamed / Vučinić, Miroslav / Kattan, Said / Kattan, Mohamed S / Mogharabian, Nasser / Phuoc, Nguyen Ho Vinh / Ngoo, Kay Seong / Alkandari, Mohammad H / Alsuhaibani, Shaheed / Sokolakis, Ioannis / Babaei, Mehdi / King, Mak Siu / Diemer, Thorsten / Gava, Marcelo M / Henrique, Raphael / Silva, Rodrigo Spinola E / Paul, Gustavo Marquesine / Mierzwa, Tiago Cesar / Glina, Sidney / Siddiqi, Kashif / Wu, Han / Wurzacher, Jana / Farkouh, Ala'a / Son, Hwancheol / Minhas, Suks / Lee, Joe / Magsanoc, Nikko / Capogrosso, Paolo / Albano, German Jose / Lewis, Sheena E M / Jayasena, Channa N / Alvarez, Juan G / Teo, Colin / Smith, Ryan P / Chua, Jo Ben M / Jensen, Christian Fuglesang S / Parekattil, Sijo / Finelli, Renata / Durairajanayagam, Damayanthi / Karna, Keshab Kumar / Ahmed, Abdelkareem / Evenson, Don / Umemoto, Yukihiro / Puigvert, Ana / Çeker, Gökhan / Colpi, Giovanni M

The world journal of men's health

2022 Volume 41, Issue 1, Page(s) 164–197

Abstract: Purpose: Varicocele is a common problem among infertile men. Varicocele repair (VR) is frequently performed to improve semen parameters and the chances of pregnancy. However, there is a lack of consensus about the diagnosis, indications for VR and its ... ...

Abstract	Purpose: Varicocele is a common problem among infertile men. Varicocele repair (VR) is frequently performed to improve semen parameters and the chances of pregnancy. However, there is a lack of consensus about the diagnosis, indications for VR and its outcomes. The aim of this study was to explore global practice patterns on the management of varicocele in the context of male infertility. Materials and methods: Sixty practicing urologists/andrologists from 23 countries contributed 382 multiple-choice-questions pertaining to varicocele management. These were condensed into an online questionnaire that was forwarded to clinicians involved in male infertility management through direct invitation. The results were analyzed for disagreement and agreement in practice patterns and, compared with the latest guidelines of international professional societies (American Urological Association [AUA], American Society for Reproductive Medicine [ASRM], and European Association of Urology [EAU]), and with evidence emerging from recent systematic reviews and meta-analyses. Additionally, an expert opinion on each topic was provided based on the consensus of 16 experts in the field. Results: The questionnaire was answered by 574 clinicians from 59 countries. The majority of respondents were urologists/uro-andrologists. A wide diversity of opinion was seen in every aspect of varicocele diagnosis, indications for repair, choice of technique, management of sub-clinical varicocele and the role of VR in azoospermia. A significant proportion of the responses were at odds with the recommendations of AUA, ASRM, and EAU. A large number of clinical situations were identified where no guidelines are available. Conclusions: This study is the largest global survey performed to date on the clinical management of varicocele for male infertility. It demonstrates: 1) a wide disagreement in the approach to varicocele management, 2) large gaps in the clinical practice guidelines from professional societies, and 3) the need for further studies on several aspects of varicocele management in infertile men.
Language	English
Publishing date	2022-06-13
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2719786-4
ISSN	2287-4690 ; 2287-4208
ISSN (online)	2287-4690
ISSN	2287-4208
DOI	10.5534/wjmh.220048
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

To top

Your last searches

Search results

Search options

Article ; Online: Detection of Chlamydia trachomatis inside spermatozoa using flow cytometry: Effects of antibiotic treatment (before and after) on sperm count parameters.

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Article: Improvement of Sperm Quality in Hyperviscous Semen following DNase I Treatment.

More links

Kategorien

Order via subito

Article: Does Varicocele Repair Improve Conventional Semen Parameters? A Meta-Analytic Study of Before-After Data.

More links

Kategorien

Order via subito

Article: Global Practice Patterns and Variations in the Medical and Surgical Management of Non-Obstructive Azoospermia: Results of a World-Wide Survey, Guidelines and Expert Recommendations.

More links

Kategorien

Order via subito

Article: Global Practice Patterns in the Evaluation of Non-Obstructive Azoospermia: Results of a World-Wide Survey and Expert Recommendations.

More links

Kategorien

Order via subito

Article: Controversy and Consensus on the Management of Elevated Sperm DNA Fragmentation in Male Infertility: A Global Survey, Current Guidelines, and Expert Recommendations.

More links

Kategorien

Order via subito

Article: Consensus and Diversity in the Management of Varicocele for Male Infertility: Results of a Global Practice Survey and Comparison with Guidelines and Recommendations.

More links

Kategorien

Order via subito