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  1. Article ; Online: An atypical presentation of visceral leishmaniasis mimicking multiple myeloma relapse.

    Benevolo, Giulia / Bertuglia, Giuseppe / Bringhen, Sara / Maletta, Francesca / Bruno, Benedetto

    American journal of hematology

    2023  Volume 99, Issue 1, Page(s) 137–141

    MeSH term(s) Humans ; Leishmaniasis, Visceral/diagnosis ; Multiple Myeloma/diagnosis ; Neoplasm Recurrence, Local
    Language English
    Publishing date 2023-11-20
    Publishing country United States
    Document type Case Reports
    ZDB-ID 196767-8
    ISSN 1096-8652 ; 0361-8609
    ISSN (online) 1096-8652
    ISSN 0361-8609
    DOI 10.1002/ajh.27147
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1251: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Early post-liver transplant use of direct-acting antivirals in naive and NS5A inhibitor-experienced HCV patients.

    Saracco, Margherita / Tandoi, Francesco / Maletta, Francesca / Balagna, Roberto / Romagnoli, Renato / Martini, Silvia

    Journal of viral hepatitis

    2022  Volume 30, Issue 3, Page(s) 201–208

    Abstract: Direct-acting antiviral drugs (DAA) are safe and effective in the HCV population. However, in patients with decompensated cirrhosis and/or active hepatocellular carcinoma or relapse to NS5A inhibitors, response rates are lower and DAA therapy must be ... ...

    Abstract Direct-acting antiviral drugs (DAA) are safe and effective in the HCV population. However, in patients with decompensated cirrhosis and/or active hepatocellular carcinoma or relapse to NS5A inhibitors, response rates are lower and DAA therapy must be postponed until after liver transplant in an era of organ shortage and suboptimal donors. We aimed to assess the prevalence of patients still HCV infected at time of transplantation over the last 3 years in our Center and describe the safety and efficacy of DAA therapy started as soon as possible after surgery. We enrolled all HCV viraemic patients transplanted in our Centre from January 2019 to March 2022. The follow-up was closed in July 2022. Among 490 liver transplants, 49 (10%) patients were still HCV viraemic at operation, 43 naive to DAA and 6 were NS5A-experienced. Median donor age was 64 years; donor risk index was 1.8. In naive patients, sofosbuvir/velpatasvir was started after a median time of 1 day from surgery, while in NS5A-experienced sofosbuvir/velpatasvir/voxilaprevir after 14.5 days (p = .001). Response rate was 98%. 1 NS5A-experienced patient experienced acute cholestatic hepatitis which promptly reverted after permanent DAA discontinuation. Hence, very early post-liver transplant HCV eradication was safe and effective thanks to a close teamwork which involved anaesthesiologists, transplant surgeons and hepatologists.
    MeSH term(s) Humans ; Middle Aged ; Sofosbuvir/therapeutic use ; Antiviral Agents/adverse effects ; Liver Transplantation ; Lactams, Macrocyclic ; Aminoisobutyric Acids ; Cyclopropanes ; Hepatitis C, Chronic/drug therapy ; Neoplasm Recurrence, Local ; Heterocyclic Compounds, 4 or More Rings/therapeutic use ; Drug Therapy, Combination ; Genotype ; Hepacivirus/genetics
    Chemical Substances Sofosbuvir (WJ6CA3ZU8B) ; Antiviral Agents ; velpatasvir (KCU0C7RS7Z) ; Lactams, Macrocyclic ; Aminoisobutyric Acids ; Cyclopropanes ; Heterocyclic Compounds, 4 or More Rings
    Language English
    Publishing date 2022-12-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 1212497-7
    ISSN 1365-2893 ; 1352-0504
    ISSN (online) 1365-2893
    ISSN 1352-0504
    DOI 10.1111/jvh.13782
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4119: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  3. Article: New Onset of Giant Cell Arteritis following ChAdOx1-S (Vaxevria

    Lo Sardo, Luca / Parisi, Simone / Ditto, Maria Chiara / De Giovanni, Rosanna / Maletta, Francesca / Grimaldi, Serena / Brussino, Luisa / Fusaro, Enrico

    Vaccines

    2023  Volume 11, Issue 2

    Abstract: We report a 78-year-old man presenting with persistent headaches in vertex and temporo-parietal area; fatigue, worsening after walking; jaw claudication; scotomas; pharyngodynia; and dry cough after the second dose of the SARS-CoV-2 vaccine (ChAdOx1-S) ... ...

    Abstract We report a 78-year-old man presenting with persistent headaches in vertex and temporo-parietal area; fatigue, worsening after walking; jaw claudication; scotomas; pharyngodynia; and dry cough after the second dose of the SARS-CoV-2 vaccine (ChAdOx1-S) administration. Laboratory findings showed an elevated C-reactive protein level and FDG-CT PET showed evidence of active large vessel vasculitis with diffuse abnormal artery uptake. Under suspicion of vasculitis, a temporal arteries biopsy was performed; the histopathologic findings demonstrated the transmural inflammatory infiltrate with giant cells, compatible with giant cell arteritis. Although the overall incidence of vaccine-triggered autoimmunity is low, rheumatologists worldwide should be aware of autoimmune diseases as a new potential adverse event of vaccines.
    Language English
    Publishing date 2023-02-13
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines11020434
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Pancreatic leiomyosarcoma: EUS findings of an uncommon pancreatic mass (with video).

    Gesualdo, Marcantonio / Bertetti, Noemi Sara / Mortara, Umberto / Maletta, Francesca / Moro, Francesco / Sacco, Marco / Bruno, Mauro / De Angelis, Claudio Giovanni / Gaia, Silvia

    Endoscopic ultrasound

    2023  Volume 12, Issue 5, Page(s) 435–436

    Language English
    Publishing date 2023-10-23
    Publishing country China
    Document type Journal Article
    ZDB-ID 2998317-4
    ISSN 2226-7190 ; 2303-9027
    ISSN (online) 2226-7190
    ISSN 2303-9027
    DOI 10.1097/eus.0000000000000037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: 2015 GIPaM Recommendations (developed in 2013; updated December, 2014; updated December, 2015).

    Balmativola, Davide / Maletta, Francesca

    Pathologica

    2016  Volume 108, Issue 1, Page(s) 1–19

    Language English
    Publishing date 2016-03
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 418229-7
    ISSN 1591-951X ; 0031-2983
    ISSN (online) 1591-951X
    ISSN 0031-2983
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 369: Show issues Location:
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  6. Article ; Online: Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features: From Echography to Genetic Profile.

    Maletta, Francesca / Falco, Enrico Costantino / Gambella, Alessandro / Metovic, Jasna / Papotti, Mauro

    The Tohoku journal of experimental medicine

    2020  Volume 252, Issue 3, Page(s) 209–218

    Abstract: In thyroid pathology, the great variety of types and the wide range of aggressiveness of thyroid cancers complicate both diagnosis and management. In 2016, a subset of noninvasive encapsulated follicular variant of papillary thyroid carcinoma was ... ...

    Abstract In thyroid pathology, the great variety of types and the wide range of aggressiveness of thyroid cancers complicate both diagnosis and management. In 2016, a subset of noninvasive encapsulated follicular variant of papillary thyroid carcinoma was reclassified as noninvasive follicular thyroid tumor with papillary-like nuclear features (NIFTP) to reduce overtreatment of this low-risk tumor that follows a benign course after surgery. Starting from a paradigmatic clinical case, in this short review, we will summarize the ultrasonography, cytological, histological and molecular features of this new entity. In the preoperative settings, the recognition of some peculiar elements may only suggest the possibility of a NIFTP, thus favoring a less aggressive surgical approach. However, the diagnosis of NIFTP can only be made after complete resection of the lesion by detecting well-defined inclusion and exclusion histopathological criteria. Since NIFTP is not 'malignant,' surgery may be considered curative with no further treatment or surveillance needed. NIFTP-related issues, including nodule size, multifocality, oncocytic changes, heterogeneous incidence across different geographical areas and its occurrence in the pediatric age, will be discussed.
    MeSH term(s) Adenocarcinoma, Follicular/diagnostic imaging ; Adenocarcinoma, Follicular/genetics ; Cell Nucleus/pathology ; Female ; Genetic Profile ; Geography ; Humans ; Middle Aged ; Neoplasm Staging ; Preoperative Period ; Retrospective Studies ; Thyroid Cancer, Papillary/diagnostic imaging ; Thyroid Cancer, Papillary/genetics ; Thyroid Gland/pathology ; Thyroid Neoplasms/diagnostic imaging ; Thyroid Neoplasms/genetics ; Treatment Outcome ; Ultrasonography/methods
    Language English
    Publishing date 2020-10-03
    Publishing country Japan
    Document type Case Reports ; Journal Article
    ZDB-ID 123477-8
    ISSN 1349-3329 ; 0040-8727
    ISSN (online) 1349-3329
    ISSN 0040-8727
    DOI 10.1620/tjem.252.209
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ua VI Zs.155: Show issues Location:
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  7. Article ; Online: Clinical and Pathological Features and Gene Expression Profiles of Clinically Aggressive Papillary Thyroid Carcinomas.

    Metovic, Jasna / Cabutti, Francesco / Osella-Abate, Simona / Orlando, Giulia / Tampieri, Cristian / Napoli, Francesca / Maletta, Francesca / Daniele, Lorenzo / Volante, Marco / Papotti, Mauro

    Endocrine pathology

    2023  Volume 34, Issue 3, Page(s) 298–310

    Abstract: Papillary thyroid carcinoma (PTC) is considered an indolent neoplasm but it may demonstrate aggressive behavior. We aimed to identify clinical and pathological characteristics and molecular signatures associated with aggressive forms of PTCs. We selected ...

    Abstract Papillary thyroid carcinoma (PTC) is considered an indolent neoplasm but it may demonstrate aggressive behavior. We aimed to identify clinical and pathological characteristics and molecular signatures associated with aggressive forms of PTCs. We selected 43 aggressive PTC cases based on the presence of metastases at the time of diagnosis, the development of distant metastasis during follow-up, and/or biochemical recurrence, and 43 PTC patients that were disease-free upon follow-up, matching them according to age, sex, pT, and pN parameters. Twenty-four pairs (a total of 48 cases) and 6 normal thyroid tissues were studied using targeted mRNA screening of cancer-associated genes employing NanoString nCounter
    MeSH term(s) Humans ; Middle Aged ; Thyroid Cancer, Papillary/genetics ; Transcriptome ; Thyroid Neoplasms/pathology ; Carcinoma, Papillary/genetics ; Carcinoma, Papillary/pathology ; Hedgehog Proteins/genetics ; Prognosis
    Chemical Substances Hedgehog Proteins
    Language English
    Publishing date 2023-05-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1033267-4
    ISSN 1559-0097 ; 1046-3976
    ISSN (online) 1559-0097
    ISSN 1046-3976
    DOI 10.1007/s12022-023-09769-x
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    Zs.A 2956: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Solitary fibrous tumor of the thyroid: report of three cases with a focus on cytological features and histological clues for malignancy.

    Santoro, Federica / Linari, Alessandra / Maletta, Francesca / Parente, Renato / Torchio, Bruno / Rossi, Esther Diana / Messuti, Ilaria / Borasi, Andrea / Volante, Marco / Papotti, Mauro

    Virchows Archiv : an international journal of pathology

    2023  Volume 483, Issue 2, Page(s) 245–250

    Abstract: Solitary fibrous tumor is a mesenchymal tumor of intermediate malignant potential characterized by a recurrent NAB2::STAT6 fusion and STAT6 nuclear expression. Primary thyroid solitary fibrous tumor is relatively uncommon, with 45 cases described in the ... ...

    Abstract Solitary fibrous tumor is a mesenchymal tumor of intermediate malignant potential characterized by a recurrent NAB2::STAT6 fusion and STAT6 nuclear expression. Primary thyroid solitary fibrous tumor is relatively uncommon, with 45 cases described in the English literature to date. Although its histologic features are characteristic, its diagnosis in the thyroid can be problematic, especially in small biopsies or cytology specimens. We herein present three new cases of thyroid solitary fibrous tumor, one of which is malignant, with new insights on the morphological spectrum and malignant potential of this tumor. We additionally provide a review of the literature with a focus on the clues and challenges of a preoperative cytological diagnosis of this tumor, which can nowadays be supported by STAT6 nuclear expression, when appropriately suspected.
    MeSH term(s) Humans ; Thyroid Gland/pathology ; Solitary Fibrous Tumors/pathology ; Hemangiopericytoma ; Biopsy ; STAT6 Transcription Factor/genetics ; Biomarkers, Tumor/analysis
    Chemical Substances STAT6 Transcription Factor ; Biomarkers, Tumor
    Language English
    Publishing date 2023-04-20
    Publishing country Germany
    Document type Review ; Case Reports ; Journal Article
    ZDB-ID 1184867-4
    ISSN 1432-2307 ; 0945-6317
    ISSN (online) 1432-2307
    ISSN 0945-6317
    DOI 10.1007/s00428-023-03542-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ud III Zs.10: Show issues Location:
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  9. Article: Endobronchial Inflammatory Myofibroblastic Tumor in a 3-Year-Old Child.

    Guanà, Riccardo / Carpino, Andrea / Miglietta, Marta / Zambaiti, Elisa / Cerrina, Alessia / Lonati, Luca / Guerrera, Francesco / Vallero, Stefano / Garofalo, Salvatore / Bardessono, Marco / Maletta, Francesca / Shilly, Steffi / Gennari, Fabrizio

    European journal of pediatric surgery reports

    2023  Volume 11, Issue 1, Page(s) e5–e9

    Abstract: Inflammatory myofibroblastic tumor (IMT) is a mesenchymal tumor that can occur at any age. However, it is primarily seen in children, with the most common site being in the lung parenchyma, usually present with rare endobronchial lesions. This case ... ...

    Abstract Inflammatory myofibroblastic tumor (IMT) is a mesenchymal tumor that can occur at any age. However, it is primarily seen in children, with the most common site being in the lung parenchyma, usually present with rare endobronchial lesions. This case reports the incidence in a 3-year-old girl diagnosed with pericardiac pneumonia treated with antibiotics with no clinical improvement. A chest computed tomography (CT) scan identified a 1.5-cm lesion in the left main bronchus. Bronchoscopy revealed complete obstruction of the left main stem bronchus. A left posterolateral thoracotomy was performed. Additionally, a left sleeve upper bronchial resection was conducted under fibroendoscopic control. Definitive histology confirmed IMT. After 2 years of endoscopic follow-up, there is no evidence of recurrence.
    Language English
    Publishing date 2023-03-09
    Publishing country Germany
    Document type Case Reports
    ZDB-ID 2674016-3
    ISSN 2194-7627 ; 2194-7619
    ISSN (online) 2194-7627
    ISSN 2194-7619
    DOI 10.1055/s-0043-1764289
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6998: Show issues Location:
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  10. Article ; Online: Neuroendocrine neoplasms of the appendix, colon and rectum.

    Volante, Marco / Grillo, Federica / Massa, Federica / Maletta, Francesca / Mastracci, Luca / Campora, Michela / Ferro, Jacopo / Vanoli, Alessandro / Papotti, Mauro

    Pathologica

    2021  Volume 113, Issue 1, Page(s) 19–27

    Abstract: Neuroendocrine neoplasms of the appendix, colon and rectum are classified according to the most recent WHO classification as neuroendocrine tumors (NET), neuroendocrine carcinomas (NEC) and mixed neuroendocrine-non neuroendocrine neoplasms (MiNENs). NECs ...

    Abstract Neuroendocrine neoplasms of the appendix, colon and rectum are classified according to the most recent WHO classification as neuroendocrine tumors (NET), neuroendocrine carcinomas (NEC) and mixed neuroendocrine-non neuroendocrine neoplasms (MiNENs). NECs and MiNENs are aggressive neoplasms requiring multimodal treatment strategies. By contrast, NETs are, in most cases, indolent lesions occurring as incidental findings in the appendix or as polyps in the rectum. While most appendiceal and rectal NETs are considered relatively non-aggressive neoplasms, a few cases, may show a more aggressive clinical course. Unfortunately, clinical/pathological characteristics to select patients at high risk of recurrence/metastases are poorly consolidated. Diagnosis is generally easy and supported by the combination of morphology and immunohistochemistry. Differential diagnostic problems are for NECs/MiNENs with poorly differentiated adenocarcinomas, when immunohistochemical neuroendocrine markers are not obviously positive, whereas for NETs they are represented by the rare appendiceal tubular and clear cell variants (which may be confused with non-neuroendocrine cancers) and rectal L-cell tumors which may be chromogranin negative and prostatic marker positive.
    MeSH term(s) Appendix ; Carcinoma, Neuroendocrine/diagnosis ; Colon ; Humans ; Infant, Newborn ; Neoplasm Recurrence, Local ; Neuroendocrine Tumors/diagnosis ; Rectum
    Language English
    Publishing date 2021-03-08
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 418229-7
    ISSN 1591-951X ; 0031-2983
    ISSN (online) 1591-951X
    ISSN 0031-2983
    DOI 10.32074/1591-951X-230
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 369: Show issues Location:
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